Keywords: ایندولامین 2،3-دی اکسیژناز 1; Indoleamine 2,3-dioxygenase 1; Imidazothiazoles; Multicomponent reactions; Cancer immunotherapy;
مقالات ISI ایندولامین 2،3-دی اکسیژناز 1 (ترجمه نشده)
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Keywords: ایندولامین 2،3-دی اکسیژناز 1; 3-HK; 3-hydroxykynurenine; 3-NP; 3-nitropropionic acid; 6âOHDA; 6-hydroxidopamine; AADC; aromatic amino acid decarboxylase; ACA; anterior cerebral artery; ADP; adenosine-5â²-diphosphate; ALDH; aldehyde dehydrogenases; ALS; amyotrophic lateral sclerosis
Keywords: ایندولامین 2،3-دی اکسیژناز 1; DSS; dextran sulfate sodium; UC; ulcerative colitis; Pal; palmatine; IBD; inflammatory bowel disease; UPLC-MS; ultra-performance liquid chromatography coupled with mass spectrometry; DAI; assessment of disease activity index; SASP; sulfasalazine; H&E; hem
Keywords: ایندولامین 2،3-دی اکسیژناز 1; Immune escape; Crystal structures; IDO1 inhibitors; Cancer immunotherapy; KP; kynurenine pathway; Trp; tryptophan; KYN; kynurenine; IDO1; indoleamine 2,3-dioxygenase 1; IDO2; indoleamine 2,3-dioxygenase 2; TDO; tryptophan 2,3-dioxygenase; IFN; interferon;
Keywords: ایندولامین 2،3-دی اکسیژناز 1; Chronic rhinosinusitis with nasal polyps; aryl hydrocarbon receptor (AhR); kynurenine; mast cell; calmodulin-dependent protein kinase II (CaMKII); AhR; Aryl hydrocarbon receptor; BMMCs; Bone marrow-derived mast cells; CaMKII; Calmodulin-dependent protei
Keywords: ایندولامین 2،3-دی اکسیژناز 1; Corneal endotheliitis; Corneal endothelial cell; Cytomegalovirus; Cytotoxic T lymphocyte reaction; Endotheliitis; Infection; Type I interferon; Innate immune response; Antigen presentation; CMV; cytomegalovirus; HCEn cell; human corneal endothelial cell;
Keywords: ایندولامین 2،3-دی اکسیژناز 1; M-CSF; macrophage colony-stimulating factor; IFN-γ; interferon-gamma; M-MÏ; macrophage differentiated from CD14 positive monocytes in the presence of M-CSF; Mγ-MÏ; macrophage differentiated from CD14 positive monocytes in the presence of M-CSF and IFN
microRNA 125a Regulates MHC-I Expression on Esophageal Adenocarcinoma Cells, Associated With Suppression of Antitumor Immune Response and Poor Outcomes of Patients
Keywords: ایندولامین 2،3-دی اکسیژناز 1; miR-125; miR-148; Antitumor Immune Response; Immune Checkpoints; CTL; cytotoxic T lymphocytes; CTLA-4; cytotoxic T lymphocyte associated protein 4; EAC; esophageal adenocarcinoma; gMFI; geometric mean fluorescence intensity; HLA-A/B/C; human leukocyte ant
Design, synthesis and structure-activity relationship study of novel naphthoindolizine and indolizinoquinoline-5,12-dione derivatives as IDO1 inhibitors
Keywords: ایندولامین 2،3-دی اکسیژناز 1; Indoleamine 2,3-dioxygenase 1; Cancer immunotherapy; Naphthoindolizine; Indolizinoquinoline-5,12-dione derivatives;
Design, synthesis and biological evaluation of novel naphthoquinone derivatives as IDO1 inhibitors
Keywords: ایندولامین 2،3-دی اکسیژناز 1; Indoleamine 2,3-dioxygenase 1; Cancer immunotherapy; Naphthoquinone derivatives; Tryptophan 2,3-dioxygenase;
Identification and preliminary structure-activity relationships of 1-Indanone derivatives as novel indoleamine-2,3-dioxygenase 1 (IDO1) inhibitors
Keywords: ایندولامین 2،3-دی اکسیژناز 1; Indoleamine 2,3-dioxygenase 1; Inhibitors; 1-Indanone derivatives; Structure-activity relationships;
Discovery of potent IDO1 inhibitors derived from tryptophan using scaffold-hopping and structure-based design approaches
Keywords: ایندولامین 2،3-دی اکسیژناز 1; Indoleamine 2,3-dioxygenase 1; Scaffold-hopping; Electrostatic potentials calculation; Induced fit docking; QM/MM;
Discovery of imidazoleisoindole derivatives as potent IDO1 inhibitors: Design, synthesis, biological evaluation and computational studies
Keywords: ایندولامین 2،3-دی اکسیژناز 1; Indoleamine 2,3-dioxygenase 1; Imidazoleisoindole; Induced fit docking; QM/MM calculation;
Discovery and evaluation of inhibitors to the immunosuppressive enzyme indoleamine 2,3-dioxygenase 1 (IDO1): Probing the active site-inhibitor interactions
Keywords: ایندولامین 2،3-دی اکسیژناز 1; IDO; Indoleamine 2,3-dioxygenase; Molecular modeling; Drug screening; Inhibitors; Mutagenesis; ACSRC; Auckland Cancer Society Research Centre; BF; benzofurazan; C129A; alanine-replacement IDO1 mutant of Cys129; GSH; reduced glutathione; IDO1; indoleamine
Systematic study of imidazoles inhibiting IDO1 via the integration of molecular mechanics and quantum mechanics calculations
Keywords: ایندولامین 2،3-دی اکسیژناز 1; Indoleamine 2,3-dioxygenase 1; Molecular dynamics simulation; MM/PBSA free energy calculation; Quantum mechanics; QM/MM optimization; Nonbonding interaction analysis;
Nitrobenzofurazan derivatives of Nâ²-hydroxyamidines as potent inhibitors of indoleamine-2,3-dioxygenase 1
Keywords: ایندولامین 2،3-دی اکسیژناز 1; Nâ²-hydroxyamidines; Mechanism-based drug design; IDO1 inhibition; High selectivity; Low cytotoxicity; IDO1; indoleamine 2,3-dioxygenase 1; TDO; tryptophan 2,3-dioxygenase; L-Trp; L-tryptophan; HTS; High throughput screening; UV-Vis; ultraviolet-visi
Peripheral indoleamine 2,3-dioxygenase 1 is required for comorbid depression-like behavior but does not contribute to neuropathic pain in mice
Keywords: ایندولامین 2،3-دی اکسیژناز 1; Neuropathic pain; Depression; Interleukin-1; Indoleamine 2,3-dioxygenase 1; Liver; Brain;
Bisphenol A suppresses Th1-type immune response in human peripheral blood mononuclear cells in vitro
Keywords: ایندولامین 2،3-دی اکسیژناز 1; BPA; bisphenol A; CTB; Cell-Titer Blue; EDTA; ethylenediaminetetraacetate; ELISA; enzyme-linked immunosorbent assay; FBS; fetal bovine serum; IDO-1; indoleamine 2,3-dioxygenase 1; GTP-GCH-I; GTP-cyclohydrolase; IFN-γ; interferon-γ; Kyn/Trp; kynurenine t
The hippocampus and TNF: Common links between chronic pain and depression
Keywords: ایندولامین 2،3-دی اکسیژناز 1; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid; AR; adrenergic receptor; BDNF; brain-derived neurotrophic factor; CNS; central nervous system; CREB; cAMP response element-binding protein; cAMP; cyclic adenosine monophosphate; ERK; extracellu