Diethylhexyl phthalate impairs insulin binding and glucose oxidation in Chang liver cells
Keywords: گیرنده انسولین; DEHP; Hepatocytes; Insulin receptor; Glucose oxidation
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Amplification of GC-rich genes by following a combination strategy of primer design, enhancers and modified PCR cycle conditions
Keywords: گیرنده انسولین; Insulin receptor; cSRC kinase; cDNA; Primer free energy (δg); Betaine; Dimethyl sulfoxide (DMSO)
Photoperiodic changes in hypothalamic insulin receptor gene expression are regulated by gonadal testosterone
Keywords: گیرنده انسولین; Photoperiodism; Insulin receptor; Testosterone; Japanese quail; Mediobasal hypothalamus
1,3-Disubstituted-imidazo[1,5-a]pyrazines as insulin-like growth-factor-I receptor (IGF-IR) inhibitors
Keywords: گیرنده انسولین; IGF-IR; IR; Tyrosine kinase inhibitors; Oncology; Imidazopyrazines; Imidazo[1,5-a]pyrazines; Insulin-like growth-factor-I receptor; Insulin receptor
Negative and positive feedback regulation of insulin in glucose-stimulated Ca2+ response in pancreatic beta cells
Keywords: گیرنده انسولین; Insulin; Pancreatic beta cell; Insulin receptor; Glucose-stimulated Ca2+ response; AMP-activated protein kinase
Regulation of SOCS-3 expression by leptin and its co-localization with insulin receptor in rat skeletal muscle cells
Keywords: گیرنده انسولین; Obesity; Leptin; Insulin receptor; SOCS-3
Characterization of the Drosophila insulin receptor promoter
Keywords: گیرنده انسولین; Insulin receptor; Diabetes; Drosophila melanogaster; Transcription
Severe deficiencies of IGF-I, IGF-II, IGFBP-3, ALS and paradoxically high-normal bone mass in a child with insulin-resistance syndrome (Rabson-Mendenhall type)
Keywords: گیرنده انسولین; Growth; Growth hormone; Hyperinsulinism; Diabetes; Insulin receptor; Donahue’s Syndrome; DXA
Testosterone deficiency impairs glucose oxidation through defective insulin and its receptor gene expression in target tissues of adult male rats
Keywords: گیرنده انسولین; Adipose tissue; Glucose oxidation; Insulin receptor; Liver; Orchidectomy; Skeletal muscles; Testosterone
Cinnamon extract and polyphenols affect the expression of tristetraprolin, insulin receptor, and glucose transporter 4 in mouse 3T3-L1 adipocytes
Keywords: گیرنده انسولین; Adipocytes; Angiogenesis; Cinnamon extract; Diabetes; Glucose transporter; Inflammation; Insulin receptor; Obesity; Polyphenol; Tristetraprolin
DM1 CTG expansions affect insulin receptor isoforms expression in various tissues of transgenic mice
Keywords: گیرنده انسولین; Myotonic dystrophy; Trinucleotide repeat; Insulin receptor; Splicing; Transgenic mice
Effect of insulin and 20-hydroxyecdysone in the fat body of the yellow fever mosquito, Aedes aegypti
Keywords: گیرنده انسولین; Insulin receptor; Akt; S6K; Target of rapamycin; RNAi
Human insulin receptor juxtamembrane domain independent insulin signaling
Keywords: گیرنده انسولین; Akt; Insulin signaling; Insulin receptor; Insulin receptor substrate 1; MAP kinase; Tyrosine phosphokinase;
The insulin-like growth factor 1 receptor in cancer: Old focus, new future
Keywords: گیرنده انسولین; Insulin-like growth factor 1 receptor; Insulin receptor; Hybrid receptor; Tyrosine kinase inhibitors; Targeted therapy; Growth factor receptor; Antibody; Cancer
Direct interaction between ER membrane-bound PTP1B and its plasma membrane-anchored targets
Keywords: گیرنده انسولین; Bimolecular Fluorescence Complementation; Insulin receptor; PKC; PTP1B; Src
Insulin receptor substrates 1 and 2 but not Shc can activate the insulin receptor independent of insulin and induce proliferation in CHO-IR cells
Keywords: گیرنده انسولین; Insulin signalling; Insulin receptor; Insulin receptor substrate; IRS1; IRS2; Shc; CHO-IR; Proliferation
shRNA and siRNA delivery to the brain
Keywords: گیرنده انسولین; Blood–brain barrier; RNAi; Endothelium; Transferrin receptor; Insulin receptor; Monoclonal antibody
Hrs is a positive regulator of VEGF and insulin signaling
Keywords: گیرنده انسولین; VEGF receptor 2; Insulin receptor; VEGF signaling; Insulin signaling; Hrs
Novel aspects on signal-transduction in the pancreatic β-cell
Keywords: گیرنده انسولین; Signal-transduction; Insulin release; Inositol phosphates; Ca2+ channel; Apolipoprotein CIII; Apoptosis; Insulin receptor; Islet of Langerhans;
Single nucleotide polymorphism in exon 17 of the insulin receptor gene is not associated with polycystic ovary syndrome in a Korean population
Keywords: گیرنده انسولین; Polycystic ovary syndrome; single nucleotide polymorphism; insulin receptor
Effects of hyperglycemia on the differential expression of insulin and insulin-like growth factor-I receptors in human normal peritoneal and adhesion fibroblasts
Keywords: گیرنده انسولین; Peritoneal fibroblasts; adhesion; insulin receptor; IGF-I receptor; hyperglycemia
Atypical protein kinase C in glucose metabolism
Keywords: گیرنده انسولین; PKC; protein kinase C; aPKC; atypical isoforms of PKC; Par6; partitioning-defective protein 6; Par3; partitioning-defective protein 3; PDK-1; 3-phosphoinositide-dependent protein kinase 1; PI3K; phosphatidylinositol 3-kinase; EGFP; enhanced greenfluoresce
Palmitic acid-induced activation of human T-lymphocytes and aortic endothelial cells with production of insulin receptors, reactive oxygen species, cytokines, and lipid peroxidation
Keywords: گیرنده انسولین; T-lymphocytes; Human endothelial cells; Unsaturated fatty acids; Palmitic acid; Oxidative stress; Insulin receptor; Cytokines
Membrane microdomain malfunction and insulin resistance in type 2 diabetes
Keywords: گیرنده انسولین; Insulin receptor; Insulin resistance; Ganglioside GM3; Lipid rafts; Detergent-resistant microdomain (DRM)
Ursolic acid and its derivative inhibit protein tyrosine phosphatase 1B, enhancing insulin receptor phosphorylation and stimulating glucose uptake
Keywords: گیرنده انسولین; PTP1B; Inhibitor; Ursolic acid; Traditional Chinese medicinal herb; Derivative; Competitive; Insulin receptor; Glucose uptake
Endogenous insulin signaling protects cultured neurons from oxygen–glucose deprivation-induced cell death
Keywords: گیرنده انسولین; insulin; insulin receptor; ischemia; oxygen–glucose deprivation; cultured neuronsDIV, days in vitro; ECS, extracellular solution; ELISA, enzyme-linked immunosorbent assay; FITC, fluorescein isothiocyanate; GLUT-4, glucose transporter 4; HEPES, 4-(2-hydrox
A miniaturized cell-based fluorescence resonance energy transfer assay for insulin-receptor activation
Keywords: گیرنده انسولین; Insulin Receptor; FRET; CFP; YFP; HTS; Imaging
Calcineurin dephosphorylates the C-terminal region of filamin in an important regulatory site: A possible mechanism for filamin mobilization and cell signaling
Keywords: گیرنده انسولین; Androgen receptor; Calpain; Calcineurin; Cyclosporin; Filamin; Insulin receptor; NFAT; Pak; Rsk; Tau
Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS
Keywords: گیرنده انسولین; adapter proteins; SH2 domain; Jak2; insulin receptor; crystal structureITC, isothermal titration calorimetry
Rin1 regulates insulin receptor signal transduction pathways
Keywords: گیرنده انسولین; Rin1; Ras; Insulin receptor; Signal transductionRin1, Ras interference 1; EGF, epidermal growth factor; Erk1/2, extracellular signal-regulated kinase; GEF, guanine nucleotide exchange factor; GFP, green fluorescent protein; JNK, Jun N-terminal kinase; p38
Role of Rab5 in insulin receptor-mediated endocytosis and signaling
Keywords: گیرنده انسولین; Signal transduction; Rab5; Endocytosis; Insulin receptor
Insulin and IGF-I phosphorylate eNOS in HUVECs by a caveolin-1 dependent mechanism
Keywords: گیرنده انسولین; eNOS; Caveolin-1; IGF-I receptor; Insulin receptor; HUVECs;
Insulin receptor tyrosine kinase activity and substrate 1 (IRS-1) expression in human myometrium and leiomyoma
Keywords: گیرنده انسولین; Leiomyoma; Myometrium; Insulin receptor; Tyrosine kinase; IRS-1;
Placental insulin and insulin-like growth factor I receptors in normal and preeclamptic pregnancies
Keywords: گیرنده انسولین; Insulin receptor; IGF-1 receptor; Placenta; Preeclampsia;
Analysis of expression of growth factor receptors in replicatively and oxidatively senescent human fibroblasts
Keywords: گیرنده انسولین; Senescence; Oxidative stress; Insulin receptor; Growth factor receptor; MitogenPDGF, platelet-derived growth factor; FGF, fibroblast growth factor; IGF, insulin-like growth factor; EGF, epidermal growth factor; SA-β-gal, senescence associated β-galactosid
IGF-I/insulin hybrid receptors in human endothelial cells
Keywords: گیرنده انسولین; IGF-I receptor; Insulin receptor; Insulin/IGF-I hybrid receptor; Endothelial cells; Human;
Comparative analysis of the signaling capabilities of the insulin receptor-related receptor
Keywords: گیرنده انسولین; IRR; Insulin receptor; IGF-I receptor; Tyrosine phosphorylation; Signal transduction;
Meg1/Grb10 overexpression causes postnatal growth retardation and insulin resistance via negative modulation of the IGF1R and IR cascades
Keywords: گیرنده انسولین; Meg1/Grb10; Insulin receptor; IGF1 receptor; Postnatal growth retardation; Insulin resistance; Type II diabetes;
Natural anti-diabetic compound 1,2,3,4,6-penta-O-galloyl-d-glucopyranose binds to insulin receptor and activates insulin-mediated glucose transport signaling pathway
Keywords: گیرنده انسولین; Type 2 diabetes; Obesity; Adipogenesis; Polyphenol; Tannic acid; α-PGG; Insulin signaling; Insulin receptor; Glucose transport;
Effect of food restriction on the insulin signalling pathway in rat skeletal muscle and adipose tissue
Keywords: گیرنده انسولین; Food restriction; Insulin; Insulin receptor; IRS-1; Glut4;
Effects of long-term caloric restriction on glucose homeostasis and on the first steps of the insulin signaling system in skeletal muscle of normal and Ames dwarf (Prop1df/Prop1df) mice
Keywords: گیرنده انسولین; Ames dwarf mice; Aging; Caloric restriction; Insulin sensitivity; Insulin receptor; IRS-1; PI 3-kinase;
Involvement of the small protein tyrosine phosphatases TC-PTP and PTP1B in signal transduction and diseases: From diabetes, obesity to cell cycle, and cancer
Keywords: گیرنده انسولین; EGFR; epidermal growth factor receptor; GHR; growth hormone receptor; IGF-IR; insulin-like growth factor I receptor; IR; insulin receptor; IRS; insulin receptor substrate; JAK; janus kinase; KO; knockout; LeptinR; leptin receptor; PDGFR; platelet derived
Insulin signaling is necessary for vitellogenesis in Drosophila melanogaster independent of the roles of juvenile hormone and ecdysteroids: female sterility of the chico1 insulin signaling mutation is autonomous to the ovary
Keywords: گیرنده انسولین; Insulin receptor substrate; Chico; Drosophila; Ovarian development; Receptor mediated endocytosis; IIS; insulin/insulin-like growth factor-like signaling; IGF; insulin-like growth factor; YP; yolk protein; CA; corpora allata; DInr; Drosophila insulin rece
Mutations in insulin signaling pathway alter juvenile hormone synthesis in Drosophila melanogaster
Keywords: گیرنده انسولین; Juvenile hormone; Insulin receptor; Insulin receptor substrate; chico; Corpus allatum; Manduca sexta allatotropin; Aging;
Expression of bFGF and NGF and their receptors in chick's auditory organ following overexposure to noise
Keywords: گیرنده انسولین; bFGF; basic fibroblast growth factor; bFGFR; basic fibroblast growth factor receptor; aFGF; acidic fibroblast growth factor; NGF; nerve growth factor; NGFR; nerve growth factor receptor; BDNF; brain-derived neurotrophic factor; GDNF; glial-cell derived ne
Caloric restriction modulates insulin receptor signaling in liver and skeletal muscle of rat
Keywords: گیرنده انسولین; Caloric restriction; Tyrosine phosphorylation; Insulin receptor; Protein tyrosine phosphatase-1B;
Differential Expression of IGF Components and Insulin Receptor Isoforms in Human Seminoma Versus Normal Testicular Tissue
Keywords: گیرنده انسولین; IGF; insulin receptor; germ cell tumor; seminoma; testis; CP; crossing point; DLK1; delta Drosophila homologue-like 1 gene; IHC; immunohistochemistry; INSL3; insulin-like hormone 3; IR; insulin receptor; IR-A; insulin receptor, isoform A; IR-B; insulin re
Getting rid of caveolins: Phenotypes of caveolin-deficient animals
Keywords: گیرنده انسولین; GPI; Glycosylphosphatidylinositol; DRMs; Detergent Resistant Membranes; IR; Insulin Receptor; VLDL; Very low density lipoprotein; MEFs; Mouse embryonic fibroblasts; Caveolin; Caveolae; Knockout mouse; Metabolic disorder; Signaling;
Early signaling interactions between the insulin and leptin pathways in bovine myogenic cells
Keywords: گیرنده انسولین; IR; insulin receptor kinase; IRS-1; insulin receptor substrate-1; PI; phosphatidylinositol; GLUT4; glucose transporter 4; ObR; leptin receptor; JAK-2; Janus kinase-2; BMC; bovine myogenic cells; Insulin resistance; Signal transduction; Insulin receptor; I
Drug and gene targeting to the brain via blood-brain barrier receptor-mediated transport systems
Keywords: گیرنده انسولین; Blood-brain barrier; Insulin receptor; Transcytosis; RNA interference;