Keywords: انتگرال; Prototype foamy virus; Integrase; Enzymology; Divalent cation; Retrovirus;
مقالات ISI انتگرال (ترجمه نشده)
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Keywords: انتگرال; Integrase; Avian leukosis virus; Ubiquitination; Non-lysine residues;
Keywords: انتگرال; AIDS; acquired immune deficiency syndrome; ALV; avian leukosis virus; AMV; avian myeloblastosis virus; APOBEC; apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like; ASLV; avian sarcoma leukosis virus; AZT; 3â² -azido-3â² -deoxythymidine; BIV;
Keywords: انتگرال; Retrovirus; Integrase; Protein purification;
Keywords: انتگرال; Endogenous retrovirus; human immunodeficiency virus; integrase; integration; lens-epithelium derived growth factor/p75; nuclear import; nuclear pore proteins; persistence; retrovirus;
Keywords: انتگرال; Topoisomerase; Integrase; Chemotherapy; Natural products; Pharmacology
Keywords: انتگرال; Integrase; Inhibitor; AIDS; HIV; Clinical treatment; Drug resistance
Keywords: انتگرال; HIV-2; Reverse transcriptase; Drug resistance; Protease; Integrase; Entry inhibitors
Keywords: انتگرال; Integrons; Integrase; Antibiotic resistance; Urbanization; Wastewater treatment;
High avidity anti-integrase antibodies discriminate recent and non-recent HIV infection: Implications for HIV incidence assay
Keywords: انتگرال; Recent HIV infection; HIV incidence; Integrase; p31; Anti integrase antibody; ELISA;
Integrase C-terminal residues determine the efficiency of feline foamy viral DNA integration
Keywords: انتگرال; Integrase; Feline foamy virus; C-terminal domain; Point mutant; Viral infectivity;
Performance of Celera RUO integrase resistance assay across multiple HIV-1 subtypes
Keywords: انتگرال; HIV-1 drug resistance; Non-subtype B; Integrase;
Design and synthesis of hybrids of diarylpyrimidines and diketo acids as HIV-1 inhibitors
Keywords: انتگرال; HIV-1 inhibitors; AIDS; Reverse transcriptase; Integrase; Molecular hybridization; Diarylpyrimidines; Diketo acids;
Diversity and evolutionary aspects of mucin binding (MucBP) domain repeats among Lactobacillus plantarum group strains through comparative genetic analysis
Keywords: انتگرال; Lactobacillus paraplantarum; Probiotic; MucBP domain repeat; Adhesion; Integrase; Transposase;
Clinical benefit of dolutegravir in HIV-1 management related to the high genetic barrier to drug resistance
Keywords: انتگرال; ART; antiretroviral therapy; TasP; Treatment-as-Prevention; NRTI; nucleoside reverse transcriptase (RT) inhibitor; NNRTI; non-nucleoside RT inhibitor; PI; protease inhibitor; INSTI; integrase strand transfer inhibitor; RAL; raltegravir; EVG; elvitegravir;
Identification and characterization of mobile genetic elements LINEs from Brassica genome
Keywords: انتگرال; aa; amino acids; BAC; bacterial artificial chromosomes; Bo; Brassica oleracea; Bp; base pair; Br; Brassica rapa; CDD; conserved domain database; CTAB; cetyltrimethylammonim bromide; Cv; cultivar; DIRs; Dictyostelium intermediate repeat sequence; DNA; Deox
Recurrent emergence of structural variants of LTR retrotransposon CsRn1 evolving novel expression strategy and their selective expansion in a carcinogenic liver fluke, Clonorchis sinensis
Keywords: انتگرال; DDH; DNA-DNA hybridization; IN; integrase; IRAP; inter-retrotransposon amplified polymorphism; LINE; long interspersed nuclear element; LTR; long terminal repeat; ORF; open reading frame; PR; protease; RH; RNase H; RT; reverse transcriptase; SINE; short
L368F/V408F double mutant of IBD of LEDGF/p75 retains interaction with M178I mutant of HIV-1 integrase
Keywords: انتگرال; HIV; Integrase; LEDGF/p75; Inter helical loops; M178; L368; IN; integrase; IBD; integrase binding domain; CCD; catalytic core domain;
A QSAR study of integrase strand transfer inhibitors based on a large set of pyrimidine, pyrimidone, and pyridopyrazine carboxamide derivatives
Keywords: انتگرال; QSAR; Integrase; Carboxamides; HIV-1; OPS; PLS;
The N-terminus of IntDOT forms hydrophobic interactions during Holliday Junction resolution
Keywords: انتگرال; Conjugative transposon; Integrative and conjugative element; CTnDOT; Integrase;
New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H
Keywords: انتگرال; HIV; Integrase; Ribonuclease H; RNase H; Diketoacid; Inhibition;
Development of a phenotypic susceptibility assay for HIV-1 integrase inhibitors
Keywords: انتگرال; HIV-1; Integrase; Phenotypic resistance; Geno2pheno; Cross-resistance; Dolutegravir;
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication
Keywords: انتگرال; Sennoside A; HIV-1; Reverse transcriptase; Antiviral activity; Plant extracts; Dual inhibitor; DKA; diketo acid; EC50; HIV-1 replication by 50%; HAART; Highly Active Anti-Retroviral Therapy; HIV-1; Human Immunodeficiency Virus type 1; IN; integrase; INIs;
Computational and synthetic approaches for developing Lavendustin B derivatives as allosteric inhibitors of HIV-1 integrase
Keywords: انتگرال; HIV-1; Integrase; LEDGF/p75; ALLINI; Computational studies; IN-LEDGF/p75 binding; ALLINI; allosteric integrase inhibitor; CCD; catalytic core domain; CTD; C-terminal domain; IBD; IN-binding domain; IN; Integrase; INLAIs; Integrase lens epithelium-derived
2-hydroxyisoquinoline-1,3(2H,4H)-diones (HIDs) as human immunodeficiency virus type 1 integrase inhibitors: Influence of the alkylcarboxamide substitution of position 4
Keywords: انتگرال; HIV-1 integrase; Two-metal binding pharmacophore; Antiretroviral; 2-hydroxyisoquinoline-1,3(2H,4H)-diones; AZT; azidothymidine; CPE; cytopathic effect; CYP; cytochrome P450; FC; fold-change in EC50 relative to wild-type strain of HIV-1; FDA; food and drug
Advances in rationally designed dual inhibitors of HIV-1 reverse transcriptase and integrase
Keywords: انتگرال; HIV; AIDS; Reverse transcriptase; Integrase; Rational drug design; Dual inhibitors;
Synthesis and evaluation of C2-carbon-linked heterocyclic-5-hydroxy-6-oxo-dihydropyrimidine-4-carboxamides as HIV-1 integrase inhibitors
Keywords: انتگرال; HIV-1; Integrase; Strand transfer; Inhibitor; Pyrimidine-4-carboxamide
Identification of minority resistance mutations in the HIV-1 integrase coding region using next generation sequencing
Keywords: انتگرال; Hiv-1; Integrase; Illumina MiSeq; Deep sequencing; Minority variants; Resistance;
Discovery of N-aryl-naphthylamines as in vitro inhibitors of the interaction between HIV integrase and the cofactor LEDGF/p75
Keywords: انتگرال; Integrase; LEDGF/p75; LEDGINs; N-aryl-naphthylamine; IN; integrase; vDNA; viral DNA; 3â²-P; 3â²-processing; ST; strand transfer; LEDGF; lens epithelium-derived growth factor; IBD; integrase binding domain; CCD; catalytic core domain; PPI; protein-prot
Crystal structure of the bacteriophage P2 integrase catalytic domain
Keywords: انتگرال; Integrase; Tyrosine recombinase; Bacteriophage P2; Integration; Site-specific recombination;
Discordant predictions of residual activity could impact dolutegravir prescription upon raltegravir failure
Keywords: انتگرال; dolutegravir; resistance; HIV-1; interpretation; integrase; treatment;
Anti-HIV diarylpyrimidine-quinolone hybrids and their mode of action
Keywords: انتگرال; Diarylpyrimidine-quinolone hybrids; HIV-1 reverse transcriptase; Integrase; Anti-HIV;
Enhancement of chitosan-mediated gene delivery through combination with phiC31 integrase
Keywords: انتگرال; Polymers; Chitosan; Gene therapy; Gene delivery; Integrase
Anti-HIV-1 activity of a tripodal receptor that recognizes mannose oligomers
Keywords: انتگرال; Antiviral agents; AIDS; HIV; Integrase; Polyphenols
Development of an integrase-based ELISA for specific diagnosis of individuals infected with HIV
Keywords: انتگرال; HIV detection; Integrase; p31; ELISA; False positive;
HIV-1-infected patients with advanced disease failing a raltegravir-containing salvage regimen in São Paulo, Brazil
Keywords: انتگرال; HIV-1; Brazil; Integrase; Raltegravir; Genotype; Resistance
In vitro analysis of the susceptibility of HIV-1 subtype A and CRF01_AE integrases to raltegravir
Keywords: انتگرال; Subtype A HIV-1; CRF01_AE HIV-1; Integrase; Raltegravir; Inhibition
Short CommunicationPharmacokinetics and dose-range finding toxicity of a novel anti-HIV active integrase inhibitor
Keywords: انتگرال; Integrase; Antiviral drug development; Pharmacokinetics; Toxicokinetics;
COP9 signalosome subunit 6 binds and inhibits avian leukosis virus integrase
Keywords: انتگرال; Integrase; Retrovirus; Avian leukosis virus; COP9 signalosome subunit 6
A study of effects of peptide fragments of bovine and human lactoferrins on activities of three key HIV-1 enzymes
Keywords: انتگرال; HIV-1; Lactoferrin; Integrase; Reverse transcriptase
Naphthyridinone (NTD) integrase inhibitors 4. Investigating N1 acetamide substituent effects with C3 amide groups
Keywords: انتگرال; Naphthyridinone; Integrase; HIV-1;
Structure-based predictors of resistance to the HIV-1 integrase inhibitor Elvitegravir
Keywords: انتگرال; Integrase; Elvitegravir; Genotype-phenotype correlation; Resistance; Computational mutagenesis; Statistical learning models;
Pyridopyrimidinone inhibitors of HIV-1 RNase H
Keywords: انتگرال; HIV; AIDS; Reverse transcriptase; Integrase; Two-metal binder; EndonucleaseADME, absorption, distribution, metabolism, excretion; AIDS, acquired immunodeficiency syndrome; Cl, clearance; CLND, chemi-luminescent nitrogen detection; DIPEA, diisopropyl ethyl
Design and discovery of 5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamide inhibitors of HIV-1 integrase
Keywords: انتگرال; CPE; cytopathic effect; LEDGF/p75; lens epithelium-derived growth factor; DMAD; dimethylacetylenedicarboxylate; IN; integrase; PK; pharmacokinetics; PD; pharmacodynamics; RAL; raltegravir; ELV; elvitegravir; HIV-1 integrase inhibitors; INSTIs; 5-Hydroxy-6
A comparative study of class 1 integrons in Acinetobacter baumannii
Keywords: انتگرال; DNA, deoxyribonucleic acid; MDR, multidrug resistance; IntI, integrase; HGT, horizontal gene transfer; IS, insertion sequence; AbaRs, antibiotic resistance islandsAcinetobacter baumannii; Integron; Integrase
Targeted gene integration using the combination of a sequence-specific DNA-binding protein and phiC31 integrase
Keywords: انتگرال; Genomic integration; Site-specific integration; Integrase; DNA-binding protein; Gene therapy;
Specific features of HIV-1 integrase inhibition by bisphosphonate derivatives
Keywords: انتگرال; HIV; Integrase; Bisphosphonates; Inhibitors; SARHAART, highly active antiretroviral therapy; IN, integrase; BP, bisphosphonate; INSTI, integrase strand transfer inhibitor; LEDGF, lens epithelium derived growth factor; RT, reverse transcriptase; VDPA, viny
Retrospective on the all-in-one retroviral nucleocapsid protein
Keywords: انتگرال; RV; retroviruses; CA; capsid; MA; matrix; NC; nucleocapsid; RT; reverse transcriptase; IN; integrase; PBS; primer binding site; gRNA; genomic RNA; DLS; dimer linkage structure; DIS; dimer initiation sequence; MuLV; murine leukemia virus; MoMuLV; Moloney M
Inhibition of HIV-1 integrase dimerization and activity with crosslinked interfacial peptides
Keywords: انتگرال; HIV; Integrase; Dimer; Inhibition;
Notable difference in anti-HIV activity of integrase inhibitors as a consequence of geometric and enantiomeric configurations
Keywords: انتگرال; Integrase; Anti-HIV; Enantiomers; Drug discovery; Cytochrome P450 isozymes;