Keywords: بیوسنتز ایزوپرنود; GGDP synthase; Inhibition; Isoprenoid biosynthesis; Bisphosphonate monoester; Prodrug;
مقالات ISI بیوسنتز ایزوپرنود (ترجمه نشده)
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Keywords: بیوسنتز ایزوپرنود; Farnesol; Isoprenoid biosynthesis; Methylerythritol phosphate; Mevalonate; Plants; Protein prenylation; DX; 1-deoxy-d-xylulose; FOS; fosmidomycin; FPP; farnesyl diphosphate; GGPP; geranylgeranyl diphosphate; HMGR; 3-hydroxy-3-methylglutaryl coenzyme A red
α-Methylation enhances the potency of isoprenoid triazole bisphosphonates as geranylgeranyl diphosphate synthase inhibitors
Keywords: بیوسنتز ایزوپرنود; GGDP synthase; Inhibition; Isoprenoid biosynthesis; Triazole; Bisphosphonate;
Bishomoisoprenoid triazole bisphosphonates as inhibitors of geranylgeranyl diphosphate synthase
Keywords: بیوسنتز ایزوپرنود; GGDP synthase; Inhibition; Isoprenoid biosynthesis; Bishomoisoprenoids; Triazole; Bisphosphonate;
HbIDI, SlIDI and EcIDI: A comparative study of isopentenyl diphosphate isomerase activity and structure
Keywords: بیوسنتز ایزوپرنود; Isopentenyl diphosphate isomerase; Isoprenoid biosynthesis; Enzyme structure-activity; Hevea brasiliensis; Solanum lycopersicum; ATR-FTIR; IDI; isopentenyl diphosphate isomerase; IPP; isopentenyl diphosphate; DMAPP; dimethylallyl diphosphate; ATR-FTIR; at
Structure of the GcpE-HMBPP complex from Thermus thermophilius
Keywords: بیوسنتز ایزوپرنود; Isoprenoid biosynthesis; GcpE/IspG; HMBPP; X-ray structure; Drug design;
Inhibition of bacterial mevalonate diphosphate decarboxylase by eriochrome compounds
Keywords: بیوسنتز ایزوپرنود; Mevalonate diphosphate decarboxylase; Mevalonate pathway; Isoprenoid biosynthesis; Enzyme inhibitors;
Kinetic characterization of an oxidative, cooperative HMG-CoA reductase from Burkholderia cenocepacia
Keywords: بیوسنتز ایزوپرنود; Burkholderia cenocepacia; HMG-CoA reductase; Enzyme cooperativity; Isoprenoid biosynthesis;
Geranyl and neryl triazole bisphosphonates as inhibitors of geranylgeranyl diphosphate synthase
Keywords: بیوسنتز ایزوپرنود; Isoprenoid biosynthesis; Inhibition; GGDP synthase; Olefin stereochemistry;
Impact of an intragenic retrotransposon on the structural integrity and evolution of a major isoprenoid biosynthesis pathway gene in Hevea brasiliensis
Keywords: بیوسنتز ایزوپرنود; Farnesyl diphosphate synthase; Hevea brasiliensis; Introns; Isoprenoid biosynthesis; Retrotransposons; SNPs;
Post-translational events and modifications regulating plant enzymes involved in isoprenoid precursor biosynthesis
Keywords: بیوسنتز ایزوپرنود; DMAPP; dimethylallyl diphosphate; FPP; farnesyl diphosphate; GGPP; geranylgeranyl diphosphate; GPP; geranyl diphosphate; HMG-CoA; 3-hydroxy-3-methylglutaryl-coenzyme A; LC; liquid chromatography; ROS; reactive oxygen species; Isoprenoid biosynthesis; Meth
Structure of the GcpE (IspG)-MEcPP complex from Thermus thermophilus
Keywords: بیوسنتز ایزوپرنود; GcpE; (E)-1-hydroxy-2-methyl-but-2-enyl-4-diphosphate synthase; MEP; 2-C-methyl-d-erythritol-4-phosphate; MEcPP; 2-C-methyl-d-erythritol-24-cyclo-diphosphate; HMBPP; (E)-1-hydroxy-2-methyl-but-2-enyl-4-diphosphate; Isoprenoid biosynthesis; GcpE; Iron-su
Growth inhibition of Mycobacterium smegmatis by prodrugs of deoxyxylulose phosphate reducto-isomerase inhibitors, promising anti-mycobacterial agents
Keywords: بیوسنتز ایزوپرنود; Isoprenoid biosynthesis; Prodrug synthesis; Deoxyxylulose 5-phosphate reducto-isomerase; Mycobacterium
Identification of novel small molecule inhibitors of 4-diphosphocytidyl-2-C-methyl-d-erythritol (CDP-ME) kinase of Gram-negative bacteria
Keywords: بیوسنتز ایزوپرنود; Isoprenoid biosynthesis; Gram-negative bacteria; 4-Diphosphocytidyl-2-C-methyl d-erythritol (CDP-ME); CDP-ME kinase; IspE; Yersinia pestis; Biodefense; Anti-terrorism; Small molecule inhibitors; Antibiotics; Antimicrobials
Enzymes of the mevalonate pathway of isoprenoid biosynthesis
Keywords: بیوسنتز ایزوپرنود; Mevalonate pathway; Isoprenoid biosynthesis; HMG-CoA; Sterol biosynthesis;
Functional genetic analysis of the Plasmodium falciparum deoxyxylulose 5-phosphate reductoisomerase gene
Keywords: بیوسنتز ایزوپرنود; DXP; deoxyxylulose 5-phosphate; DXR; deoxyxylulose phosphate reductoisomerase; MEP; 2C-methyl-d-erythritol 5-phosphate; PCR; polymerase chain reaction; Malaria; Isoprenoid biosynthesis; Drug targets;
Synthesis and biological evaluation of a series of aromatic bisphosphonates
Keywords: بیوسنتز ایزوپرنود; Bisphosphonate; GGDPS; Enzyme inhibitor; Isoprenoid biosynthesis; Protein prenylation; Geranylgeranyl diphosphate
The Isogene 1-Deoxy-D-Xylulose 5-Phosphate Synthase 2 Controls Isoprenoid Profiles, Precursor Pathway Allocation, and Density of Tomato Trichomes
Keywords: بیوسنتز ایزوپرنود; Isoprenoid biosynthesis; methyl-D-erythritol 4-phosphate (MEP) pathway; 1-deoxy-D-xylulose 5-phosphate synthase 2 (DXS2); RNA interference (RNAi); trichomes; cross-talk; feedback regulation; GC–C–IRMS
Molecular and functional characterization of a cDNA encoding 4-hydroxy-3-methylbut-2-enyl diphosphate reductase from Dunaliella salina
Keywords: بیوسنتز ایزوپرنود; Carotenogenesis; Dunaliella salina; 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase; Isoprenoid biosynthesis; Methylerythritol phosphate pathwayDXS, 1-deoxy-d-xylulose 5-phosphate synthase; DXR, 1-deoxy-d-xylulose 5-phosphate reductoisomerase; DMAPP, d
Detection of nonsterol isoprenoids by HPLC–MS/MS
Keywords: بیوسنتز ایزوپرنود; Isoprenoid biosynthesis; Mevalonate kinase deficiency; Mass spectrometry; Farnesyl pyrophosphate; Geranylgeranyl pyrophosphate
Ultrafast pyrosequencing of Corynebacterium kroppenstedtii DSM44385 revealed insights into the physiology of a lipophilic corynebacterium that lacks mycolic acids
Keywords: بیوسنتز ایزوپرنود; Corynebacterium kroppenstedtii; Pyrosequencing; Biotin biosynthesis; Isoprenoid biosynthesis; Mevalonate pathway; Mycolic acid biosynthesis; Lipophilism; β-Oxidation
Human mevalonate diphosphate decarboxylase: Characterization, investigation of the mevalonate diphosphate binding site, and crystal structure
Keywords: بیوسنتز ایزوپرنود; Human mevalonate diphosphate decarboxylase; Isoprenoid biosynthesis; Mevalonate pathway; Competitive inhibition; Active site function; Protein structure
Synthesis of β- and γ-oxa isosteres of fosmidomycin and FR900098 as antimalarial candidates
Keywords: بیوسنتز ایزوپرنود; Isoprenoid biosynthesis; Fosmidomycin; DOXP reductoisomerase; Methylerythritol phosphate pathway
Molecular cloning and characterization of two cDNAs encoding 1-deoxy-d-xylulose 5-phosphate reductoisomerase from Hevea brasiliensis
Keywords: بیوسنتز ایزوپرنود; 1-Deoxy-d-xylulose 5-phosphate reductoisomerase; Ethylene or ethephon; Hevea brasiliensis; Isoprenoid biosynthesis; Rubber biosynthesisCDP-Star, disodium 2-chloro-5-(4-methoxyspiro{1,2-dioxetane-3,2′-(5′-chiro)tricyclo[3.3.1.13,7]decan}-4-yl)-1-phenyl pho
Isoprenoid biosynthesis via the methylerythritol phosphate pathway: GcpE and LytB, two novel iron–sulphur proteins
Keywords: بیوسنتز ایزوپرنود; Isoprenoid biosynthesis; Methylerythritol phosphate pathway; GcpE; LytB; Iron–sulphur proteinsBiosynthèse des isoprénoïdes; Voie du méthylérythritol phosphate; GcpE; LytB; Protéines fer–soufre
The methylerythritol phosphate pathway for isoprenoid biosynthesis in coccidia: Presence and sensitivity to fosmidomycin
Keywords: بیوسنتز ایزوپرنود; Apicomplexa; Coccidia; Cryptosporidium parvum; Cryptosporidium hominis; Eimeria tenella; Plasmodium falciparum; Toxoplasma gondii; Fosmidomycin; Isoprenoid biosynthesis; MEP; methylerythritol phosphate; MVA; mevalonic acid; RT-PCR; reverse transcription-p
Purification, properties and heteromeric association of type-1 and type-2 lepidopteran farnesyl diphosphate synthases
Keywords: بیوسنتز ایزوپرنود; Farnesyl diphosphate synthase; Lepidoptera; Juvenile hormone; Isoprenoid biosynthesis
The Crystal Structure of Human Isopentenyl Diphosphate Isomerase at 1.7 Å Resolution Reveals its Catalytic Mechanism in Isoprenoid Biosynthesis
Keywords: بیوسنتز ایزوپرنود; IPP, isopentenyl diphosphate; DMAPP, dimethylallyl diphosphateisopentenyl diphosphate isomerase; isoprenoid biosynthesis; IPP isomerase; isomerization; crystal structure
Dynamic pathway allocation in early terpenoid biosynthesis of stress-induced lima bean leaves
Keywords: بیوسنتز ایزوپرنود; Phaseolus lunatus; Léguminosae; Lima bean; Isoprenoid biosynthesis; Cross talk; 1-Deoxy-d-xylulose; Mevalonate; Terpenoids; Volatiles; Isotopically labeled; Inhibitors; IRMS; Isotopic discrimination;
Reconstitution of an apicoplast-localised electron transfer pathway involved in the isoprenoid biosynthesis of Plasmodium falciparum
Keywords: بیوسنتز ایزوپرنود; DMAPP, dimethylallyl diphosphate; DOXP, 1-deoxy-d-xylulose-5-phosphate; Fd, ferredoxin; FNR, ferredoxin-NADP+ reductase; HMBPP, (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate; IPP, isopentenyl diphosphateMalaria; Apicoplast; Isoprenoid biosynthesis; Ferred
Sensing cell stress and transformation through Vγ9Vδ2 T cell-mediated recognition of the isoprenoid pathway metabolites
Keywords: بیوسنتز ایزوپرنود; Immunology; T lymphocytes; Gamma/delta T cell receptor; Isoprenoid biosynthesis; ABP; aminobiphosphonate; Ag; antigen; ApoA1; apolipoprotein A1; AS; ATP synthase; DC; dendritic cell; DMAPP; dimethylallyl pyrophosphate; DOXP; 1-deoxy-d-xylulose-5-phosphate
A spectrophotometric assay for the determination of 4-diphosphocytidyl-2-C-methyl-d-erythritol kinase activity
Keywords: بیوسنتز ایزوپرنود; 4-Diphosphocytidyl-2-C-methyl-d-erythritol kinase; Spectrophotometric assay; Pyruvate kinase; Lactate dehydrogenase; Isoprenoid biosynthesis; 2-C-methyl-d-erythritol 4-phosphate;
A colorimetric assay for the determination of 4-diphosphocytidyl-2-C-methyl-d-erythritol 4-phosphate synthase activity
Keywords: بیوسنتز ایزوپرنود; 4-Diphosphocytidyl-2-C-methyl-d-erythritol 4-phosphate synthase; Colorimetric assay; Malachite green; Pyrophosphatase; Isoprenoid biosynthesis; 2-C-Methyl-d-erythritol 4-phosphate pathway;