Domoic acid induced seizures progress to a chronic state of epilepsy in rats
Keywords: اسید کرییک; Domoic acid; Amnesic shellfish poison; Epilepsy; Kainic acid; Sea lion;
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Neuroprotective effect of Cu,Zn-superoxide dismutase fused to a TCTP-derived protein transduction domain
Keywords: اسید کرییک; Kainic acid; Paraquat; Protein transduction domain; Superoxide dismutase; Translationally controlled tumor protein
Kainate postconditioning restores LTP in ischemic hippocampal CA1: Onset-dependent second pathophysiological stress
Keywords: اسید کرییک; 2-vessel occlusion; CA1; Kainic acid; LTP; Postconditioning; Spine density
Capsaicin prevents kainic acid-induced epileptogenesis in mice
Keywords: اسید کرییک; Epileptogenesis; Capsaicin; Kainic acid; Hippocampus; Neuroprotection; Electroencephalogram
Fluctuating and constant valproate administration gives equivalent seizure control in rats with genetic and acquired epilepsy
Keywords: اسید کرییک; Absence epilepsy; GAERS; Temporal lobe epilepsy; Kainic acid; Status epilepticus; Slow-release formulation
Ketogenic diet-induced peroxisome proliferator-activated receptor-γ activation decreases neuroinflammation in the mouse hippocampus after kainic acid-induced seizures
Keywords: اسید کرییک; Ketogenic diet; Kainic acid; PPARγ; COX-2; Hippocampus;
Upregulation of arginine vasopressin synthesis in the rat hypothalamus after kainic acid-induced seizures
Keywords: اسید کرییک; Kainic acid; Vasopressin; Paraventricular nucleus; Supraoptic nucleus; NMDA receptor
Neurogenesis in the epileptic brain: a brief overview from temporal lobe epilepsy
Keywords: اسید کرییک; dentate gyrus; seizures; pilocarpine; kainic acid; antiepileptic drugs
Epileptiform response of CA1 neurones to convulsant stimulation by cyclothiazide, kainic acid and pentylenetetrazol in anaesthetized rats
Keywords: اسید کرییک; Epilepsy model; Hippocampus; Convulsant; Cyclothiazide; Kainic acid; Pentylenetetrazol
Kainic acid-induced early genes activation and neuronal death in the medial extended amygdala of rats
Keywords: اسید کرییک; Fos; Kainic acid; Gene activation; Neurodegeneration; Amygdala; Epilepsy; Wistar ratBSTM, medial division of bed nucleus of the stria terminalis; BSTMa, anterior medial bed nucleus of the stria terminalis; BSTMp, posterior medial bed nucleus of the stria
A subset of μ-opioid receptor-expressing cells in the rostral ventromedial medulla contribute to thermal hyperalgesia in experimental neuropathic pain
Keywords: اسید کرییک; CCI, chronic constrictive injury; FJB, Fluoro-Jade B; KA, kainic acid; MOR, μ-opioid receptor; PBS, phosphate–buffered saline; RVM, rostral ventromedial medulla; TPH, tryptophan hydroxylaseChronic constrictive injury; Descending facilitation; Kainic acid;
Store-operated calcium entry modulates neuronal network activity in a model of chronic epilepsy
Keywords: اسید کرییک; SOCE; Store-operated calcium entry; STIM; Stromal interaction molecule; 2-APB; 2-aminoethoxydiphenyl borate; IP3; Inositol 1,4,5-trisphosphate; IP3R; IP3 receptor; ER; Endoplasmic reticulum; SOC; Store-operated channels; ICRAC; Calcium-release activated c
Protective effect of 2,2′-dithienyl diselenide on kainic acid-induced neurotoxicity in rat hippocampus
Keywords: اسید کرییک; rats; kainic acid; seizures; hippocampus; oxidative stress; seleniumAMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; ANOVA, analysis of variance; DCHF, fluorescent dichlorofluorescein; DCHF-DA, 2′, 7′-dichlorofluorescein diacetate; DNP
Neurodegeneration, Neuroprotection, and Disease-Oriented NeuroscienceResearch PaperDelayed neuroprotection by riluzole against excitotoxic damage evoked by kainate on rat organotypic spinal cord cultures
Keywords: اسید کرییک; spinal cord injury; motoneuron; kainic acid; neuroprotection; excitotoxicity; glutamate; ALS; amyotrophic lateral sclerosis; ANOVA; analysis of variance; DAPI; 4',6-diamidino-2-phenylindole; DIV; days in vitro; DME/HIGH; Dulbecco's modified Eagle's medium
Galantamine potentiates the protective effect of rofecoxib and caffeic acid against intrahippocampal Kainic acid-induced cognitive dysfunction in rat
Keywords: اسید کرییک; Galantamine; Kainic acid; Mitochondria; Oxidative damage; Rofecoxib
Repeated citalopram administration counteracts kainic acid-induced spreading of PSA-NCAM-immunoreactive cells and loss of reelin in the adult mouse hippocampus
Keywords: اسید کرییک; Kainic acid; Epilepsy; Brain plasticity; PSA-NCAM; Reelin; Citalopram
Molecular imaging in neuroscience research with small-animal PET in rodents
Keywords: اسید کرییک; ACh; acetylcholine; BP; binding potential; CBZ; central benzodiazepine; [18F]FDG; 2-deoxy-2-[18F]fluoro-d-glucose; FFMZ; fluoroflumazenil; GABA; γ-aminobutyric acid; 5-HT; 5-hydroxytryptamine (serotonin); KA; kainic acid; mGluRs; metabotropic glutamate r
Hippocampal neuronal death induced by kainic acid and restraint stress is suppressed by exercise
Keywords: اسید کرییک; chronic exercise; kainic acid; restraint stress; CREB; CaMKII; ERK1/2AD, Alzheimer's disease; CaMKII, calcium/calmodulin-dependent protein kinase II; CREB, cAMP response element-binding protein; ERK1/2, extracellular signal-regulated kinase; Gc, glucocort
Prenatal corticosteroid exposure alters early developmental seizures and behavior
Keywords: اسید کرییک; CAN, canrenoic acid; HC, hydrocortisone; HPA, hypothalamus–pituitary–adrenal; KA, kainic acid; MR, mineralocorticoid; NPY, neuropeptide Y; P, postnatal day; PBS, phosphate-buffered saline; RI, retention indexBetamethasone; Hydrocortisone; Kainic acid; Flu
Research ReportChronic electrographic seizure reduces glutamine and elevates glutamate in the extracellular fluid of rat brain
Keywords: اسید کرییک; Glutamate; Glutamine; Extracellular; Kainate; Seizure; Epilepsy; EAAT2; excitatory amino acid transporter subtype 2; ECF; extracellular fluid; GLU; glutamate; GLN; glutamine; GS; glutamine synthetase; HYP; hypersynchronous; KA; kainic acid; LVF; low-volta
An ethnomedicinal, phytochemical and pharmacological profile of Desmodium gangeticum (L.) DC. and Desmodium adscendens (Sw.) DC.
Keywords: اسید کرییک; AA; arachidonic acid; ABTS; 2,2â²-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid); AChE; acetylcholinesterase; AL; alcohol; ALP; alkaline phosphatase; ASP; aspirin; BST; brine shrimp lethality bioassay; CAT; catalase; ChTX; charybdotoxin; CNS; central
Kudzu root: Traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases
Keywords: اسید کرییک; ACE2; angiotensin-converting enzyme 2; ADP; adenosine diphosphate; AGE; advanced glycation end-products; APV; DL-2-amino-5-phosphonovaleric acid; AT1; angiotensin II type I receptor; Aβ25-35; β-amyloid; Bcl-2; B-cell leukemia/lymphoma-2; BKCa; large-con
Altered expression of sphingosine kinase 1 and sphingosine-1-phosphate receptor 1 in mouse hippocampus after kainic acid treatment
Keywords: اسید کرییک; Kainic acid; Sphingosine kinase 1; Sphingosine-1-phosphate receptor 1; Hippocampus; Mice;
Neuroprotective effects of FK506 against excitotoxicity in organotypic hippocampal slice culture
Keywords: اسید کرییک; FK506; Kainic acid; Organotypic hippocampal slice culture; Neuroprotection
Challenge dose of methamphetamine affects kainic acid-induced seizures differently depending on prenatal methamphetamine exposure, sex, and estrous cycle
Keywords: اسید کرییک; Methamphetamine; Kainic acid; Seizures; Sex difference; Estrous cycle
Anticonvulsant effects of methyl ethyl ketone and diethyl ketone in several types of mouse seizure models
Keywords: اسید کرییک; Anticonvulsant; Ketone body; Pentylenetetrazole; Kainic acid; Electroshock-induced convulsion; Methyl-6,7-dimethoxy-4-ethyl-β-carboline-3-carboxylate
Neuroprotective effects of stanniocalcin 2 following kainic acid-induced hippocampal degeneration in ICR mice
Keywords: اسید کرییک; Stanniocalcin 2; Kainic acid; Microglial activation; BV2 cells
Effects of early postnatal caffeine exposure on seizure susceptibility of rats are age- and model-dependent
Keywords: اسید کرییک; Caffeine; Development; Rat; Seizures; N-Methyl-d-aspartate; Kainic acid
Cognitive, Behavioral, and Systems NeuroscienceResearch PaperProlactin reduces the damaging effects of excitotoxicity in the dorsal hippocampus of the female rat independently of ovarian hormones
Keywords: اسید کرییک; prolactin; hippocampus; excitotoxicity; kainic acid; seizure; KA; kainic acid; Neu-N; neuronal nuclei; OVX; ovariectomized; PRL; prolactin; PRL-R; prolactin receptor;
Kainic acid and 3-Nitropropionic acid induced expression of laminin in vascular elements of the rat brain
Keywords: اسید کرییک; Laminin; Kainic acid; 3-NPA; Fluoro-Jade C; Neurodegeneration
Cyto-, axo- and dendro-architectonic changes of neurons in the limbic system in the mouse pilocarpine model of temporal lobe epilepsy
Keywords: اسید کرییک; BDNF; brain-derived neurotrophic factor; CB; calbindin; BLA; basolateral amygdala; ChAT; choline acetyltransferase; CR; calretinin; CTB; cholera toxin B subunit; Dsub; dorsal subiculum; EC; entorhinal cortex; EEG; electroencephalography; fMRI; functional
Aggrecan expression, a component of the inhibitory interneuron perineuronal net, is altered following an early-life seizure
Keywords: اسید کرییک; Aggrecan; Perineuronal net; Extracellular matrix; Hippocampus; Kainic acid; Neonatal seizure; Interneurons; Parvalbumin;
Diurnal rhythms of spontaneous recurrent seizures and behavioral alterations of Wistar and spontaneously hypertensive rats in the kainate model of epilepsy
Keywords: اسید کرییک; Wistar rats; Spontaneous hypertensive rats; Kainic acid; Diurnal rhythms; Recurrent spontaneous seizures; Open field; Elevated plus maze; Hole board;
Increased sensitivity to kainic acid in a genetic model of reduced NMDA receptor function
Keywords: اسید کرییک; Schizophrenia; Glutamate; Kainic acid; NMDA receptor; Hippocampus; Cerebral cortex; Kainic acid antagonist
Neuroprotective potential of mGluR5 antagonist MTEP: effects on kainate-induced excitotoxicity in the rat hippocampus
Keywords: اسید کرییک; 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]-pyridine (MTEP); mGlu5 antagonist; kainic acid; hippocampus; excitotoxicity; neuroprotection
Protein kinase Cdelta is associated with 14-3-3 phosphorylation in seizure-induced neuronal death
Keywords: اسید کرییک; Apoptosis; Epilepsy; Kainic acid; Protein kinase Cdelta; 14-3-3;
An arcuate-ventrolateral periaqueductal gray reciprocal circuit participates in electroacupuncture cardiovascular inhibition
Keywords: اسید کرییک; Glutamatergic receptors; Acetylcholine; Kainic acid; Kynurenic acid; Retrograde tracer
Sinapic acid attenuates kainic acid-induced hippocampal neuronal damage in mice
Keywords: اسید کرییک; Sinapic acid; Kainic acid; NeuroprotectionSA, sinapic acid; KA, kainic acid; AD, Alzheimer’s disease; PD, Parkinson’s disease; Aβ, amyloid-β peptide; NT, nitrotyrosine; NOS, nitric oxide synthase; NO, nitric oxide; iNOS, inducible nitric oxide synthase; n
Kainate-induced delayed onset of excitotoxicity with functional loss unrelated to the extent of neuronal damage in the in vitro spinal cord
Keywords: اسید کرییک; spinal cord injury; kainic acid; kainate; fictive locomotion; motoneuron; organotypic cultureAPV, aminophosphonovalerate; ANOVA, analysis of variance; CNQX, 6-cyano-7-nitroquinoxaline-2,3-dione; CTR, control; CV, coefficient of variation; DAPI, 4′,6-diami
Neuroprotection by glutamate receptor antagonists against seizure-induced excitotoxic cell death in the aging brain
Keywords: اسید کرییک; Kainic acid; MK-801; NBQX; Neuronal damage; Hippocampus; Mouse strain
Molecular NeuroscienceResearch PaperThe time-dependent effect of lipopolysaccharide on kainic acid-induced neuronal death in hippocampal CA3 region: possible involvement of cytokines via glucocorticoid
Keywords: اسید کرییک; LPS; kainic acid; hippocampus; cytokines; glucocorticoid; neuronal death; ANOVA; analysis of variance; EDTA; ethylenediamine tetra acetic acid; Gc; glucocorticoid; GFAP; glial fibrillary acidic protein; GR; glucocorticoid receptor; IR; immunoreactivities;
Fcγ receptors contribute to pyramidal cell death in the mouse hippocampus following local kainic acid injection
Keywords: اسید کرییک; gamma subunit of FcRs; FcγRlll; FcγRllB; parvalbumin neuron; B6; C57BL/6N; COX-2; cyclooxygenase-2; DAB; 2,3,3â²-diaminobenzidine tetrahydrochloride; FcγRs; receptors for Fc portion of immunoglobulin G (IgG); FcRγ; gamma subunit coupled with FcγRl a
Levetiracetam suppresses development of spontaneous EEG seizures and aberrant neurogenesis following kainate-induced status epilepticus
Keywords: اسید کرییک; Status epilepticus; Kainic acid; Ectopic granule cell; Neurogenesis; Levetiracetam; Adult rat
Spatial memory is enhanced in long-living Ames dwarf mice and maintained following kainic acid induced neurodegeneration
Keywords: اسید کرییک; Ames dwarf; Hippocampus; Spatial memory; Barnes maze; Kainic acid
The hippocampus of Ames dwarf mice exhibits enhanced antioxidative defenses following kainic acid-induced oxidative stress
Keywords: اسید کرییک; Ames dwarf; Hippocampus; Oxidative stress; Glutathione; Glutathione peroxidase; Kainic acid;
Lactation is a natural model of hippocampus neuroprotection against excitotoxicity
Keywords: اسید کرییک; Hippocampus; Lactation; Neuroprotection; Excitotoxicity; Kainic acid; Fluoro-Jade C
Ketogenic diet attenuates kainic acid-induced hippocampal cell death by decreasing AMPK/ACC pathway activity and HSP70
Keywords: اسید کرییک; Ketogenic diet; Kainic acid; AMPK; ACC; HSP70; Hippocampus;
Antiepileptic potential and behavioral profile of l-pGlu-(2-propyl)–l-His–l-ProNH2, a newer thyrotropin-releasing hormone analog
Keywords: اسید کرییک; NP-647; Thyrotropin-releasing hormone analog; Epilepsy; Pentobarbital; Functional observation battery; Picrotoxin; Kainic acid; Pentylenetetrazole; Locomotion
Kainic acid intraocular injections during the postnatal critical period induce plastic changes in the visual system
Keywords: اسید کرییک; Plasticity; Optic nerve; Development; Kainic acid; Visual system; Postnatal critical period
Neuro-protective effects of carbamazepine on sleep patterns and head and body shakes in kainic acid-treated rats
Keywords: اسید کرییک; Carbamazepine; Kainic acid; Sleep; Head and body shakes; 5-HT; Rat