Keywords: جهش KRAS; Non-small cell lung cancer; KRAS mutation; Chemotherapy; Outcome; Type of KRAS mutation;
مقالات ISI جهش KRAS (ترجمه نشده)
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Keywords: جهش KRAS; Autoimmune pancreatitis; Endoscopic ultrasound-guided fine-needle aspiration; Cytology; KRAS mutation;
Keywords: جهش KRAS; Non-small-cell lung cancer; KRAS mutation; Circulating tumor cells; Circulating tumor DNA;
Keywords: جهش KRAS; EGFR mutation; KRAS mutation; ROS1; Non-small cell lung cancer
KRAS and 2 rare PI3KCA mutations coexisting in a metastatic colorectal cancer patient with aggressive and resistant disease
Keywords: جهش KRAS; mCRC; KRAS mutation; PI3KCA mutation; FIr-B/FOx; Anti-VEGF; Anti-EGFR;
ERBB2 mutation: A promising target in non-squamous cervical cancer
Keywords: جهش KRAS; ICC; invasive cervical cancer; HPV; human papillomavirus; IHC; immunohistochemistry; FISH; fluorescence in situ hybridization; TKIs; tyrosine kinase inhibitors; Cervical cancer; ERBB2 mutation; PIK3CA mutation; KRAS mutation; Targeted therapy;
KRAS mutation and immunohistochemical profile in intraductal papillary neoplasm of the intrahepatic bile ducts
Keywords: جهش KRAS; KRAS mutation; Immunohistochemical profile; Intraductal papillary neoplasm of bile duct; Malignant progression;
Phase 2 Study of the HSP-90 Inhibitor AUY922 in Previously Treated and Molecularly Defined Patients with Advanced Non-Small Cell Lung Cancer
Keywords: جهش KRAS; NSCLC; AUY922; HSP90 inhibitor; EGFR mutation; KRAS mutation; ALK rearrangement;
KRAS targeting antibody synergizes anti-cancer activity of gemcitabine against pancreatic cancer
Keywords: جهش KRAS; Pancreatic cancer; KRAS mutation; Antibody drug;
Cytostatic hydroxycoumarin OT52 induces ER/Golgi stress and STAT3 inhibition triggering non-canonical cell death and synergy with BH3 mimetics in lung cancer
Keywords: جهش KRAS; KRAS mutation; Non-small cell lung cancer; Coumarin; STAT3; BH3 mimetics; Immunogenic cell death;
Carcinoma seroso peritoneal y adenocarcinoma mucinoso apendicular sincrónicos. Estudio inmunohistoquÃmico y molecular
Keywords: جهش KRAS; Carcinoma sincrónico; Mutación de KRAS; Adenocarcinoma mucinoso apendicular; Carcinoma seroso peritoneal; Synchronous carcinoma; KRAS mutation; Mucinous appendicular adenocarcinoma; Serous peritoneal carcinoma;
Original articleEGFR and KRAS molecular genotyping for pulmonary carcinomas: Feasibility of a simple and rapid technique implementable in any department of pathology
Keywords: جهش KRAS; Lung cancer; Molecular pathology; EGFR mutation; KRAS Mutation; Fully automated real-time PCR;
Original ArticleThe HSP90 inhibitor, NVP-AUY922, attenuates intrinsic PI3K inhibitor resistance in KRAS-mutant non-small cell lung cancer
Keywords: جهش KRAS; NSCLC; HSP90 inhibitor; PI3K inhibitor; KRAS mutation; Combination therapy; NSCLC; non-small cell lung cancer; CI; combination index;
Radiosensitivity of Colon and Rectal Lung Oligometastasis Treated With Stereotactic Ablative Radiotherapy
Keywords: جهش KRAS; Colon cancer; High radiation dose; KRAS mutation; Rectal cancer; Survival;
Leptomycin B reduces primary and acquired resistance of gefitinib in lung cancer cells
Keywords: جهش KRAS; CRM1; chromosome region maintenance 1; EGFR; epidermal growth factor receptor; EMT; epithelial-mesenchymal transition; LMB; leptomycin B; MTT; 3-(4,5-dimetrylthiazol)-2,5-diphenyltetrazolium bromide; NSCLC; non-small cell lung cancer; TKIs; tyrosine kinas
KRAS Mutations in Canine and Feline Pancreatic Acinar Cell Carcinoma
Keywords: جهش KRAS; companion animal; KRAS mutation; model; pancreatic acinar cell carcinoma;
Case report: Durable response to afatinib in a patient with lung cancer harboring two uncommon mutations of EGFR and a KRAS mutation
Keywords: جهش KRAS; EGFR mutation; KRAS mutation; Afatinib; Non-small cell lung cancer; Tyrosine kinase inhibitor;
The clinical significance of K-ras mutation in endometrial “surface epithelial changes” and their associated endometrial adenocarcinoma
Keywords: جهش KRAS; Surface epithelial changes; Endometrial carcinoma; KRAS mutation
Targeting KRAS for diagnosis, prognosis, and treatment of pancreatic cancer: Hopes and realities
Keywords: جهش KRAS; Pancreatic ductal adenocarcinoma; KRAS mutation; Quantitative PCR; Solid pancreatic masses; Prognosis; MEK inhibitors;
Large Cell Neuroendocrine Carcinoma of the Lung: Clinico-Pathologic Features, Treatment, and Outcomes
Keywords: جهش KRAS; Brain metastases; KRAS mutation; Platinum-etoposide chemotherapy; Small cell lung carcinoma; Stage IV;
Efficacy of Pemetrexed-Based Chemotherapy in Patients with ROS1 Fusion-Positive Lung Adenocarcinoma Compared with in Patients Harboring Other Driver Mutations in East Asian Populations
Keywords: جهش KRAS; EGFR mutation; EML4-ALK fusion; KRAS mutation; pemetrexed-based therapy; ROS1 fusion;
The HSP90 inhibitor, NVP-AUY922, sensitizes KRAS-mutant non-small cell lung cancer with intrinsic resistance to MEK inhibitor, trametinib
Keywords: جهش KRAS; NSCLC; HSP90 inhibitor; MEK inhibitor; KRAS mutation; Combination therapy;
Mathematical modeling of drug resistance due to KRAS mutation in colorectal cancer
Keywords: جهش KRAS; Colorectal cancer; Mathematical model; Monoclonal antibody resistance; KRAS mutation;
Programmed Cell Death Ligand 1 Expression in Resected Lung Adenocarcinomas: Association with Immune Microenvironment
Keywords: جهش KRAS; KRAS mutation; Lung adenocarcinoma; PD-L1; Smoking; Tumor microenvironment;
A teenager with lung mucinous adenocarcinoma harboring a KRAS mutation arising in type 1 congenital cystic adenomatoid malformation (CCAM)
Keywords: جهش KRAS; Invasive mucinous adenocarcinoma; Teenager; Type I Congenital cystic adenomatoid malformation (CCAM); KRAS mutation; Lung adenocarcinoma;
Improved sensitivity of circulating tumor DNA measurement using short PCR amplicons
Keywords: جهش KRAS; Plasma; cfDNA; KRAS mutation; qPCR;
Diagnostic application of KRAS mutation testing in uterine microglandular proliferations
Keywords: جهش KRAS; KRAS mutation; Microglandular hyperplasia; Endometrial adenocarcinoma; Endometrial complex mucinous lesions; Single-starnd conformation polymorphism
Epidemiological-molecular evidence of metabolic reprogramming on proliferation, autophagy and cell signaling in pancreas cancer
Keywords: جهش KRAS; Pancreas cancer; Cancer metabolism; KRAS mutation; Autophagy; Glycolysis;
Monotherapy Administration of Sorafenib in Patients With Non–Small Cell Lung Cancer (MISSION) Trial : A Phase III, Multicenter, Placebo-Controlled Trial of Sorafenib in Patients with Relapsed or Refractory Predominantly Nonsquamous Non–Small-Cell Lung Can
Keywords: جهش KRAS; Non-small-cell lung cancer; Molecular targeted therapy; Sorafenib; KRAS mutation; EGFR mutation
Expression of PD-1 and Its Ligands, PD-L1 and PD-L2, in Smokers and Never Smokers with KRAS-Mutant Lung Cancer
Keywords: جهش KRAS; PD-1; PD-L1; PD-L2; KRAS mutation; Lung cancer; Cancer immunotherapy
KRAS insertions in colorectal cancer: What do we know about unusual KRAS mutations?
Keywords: جهش KRAS; Molecular pathology; Genetics; KRAS mutation; Colorectal cancer
High-stage urachal adenocarcinoma can be associated with microsatellite instability and KRAS mutations
Keywords: جهش KRAS; Urachal carcinoma; Microsatellite instability; KRAS mutation; BRAF mutation; BRAF V600E; Cancer
MEK inhibition in non-small cell lung cancer
Keywords: جهش KRAS; KRAS mutation; Targeted therapy; MEK inhibition; Selumetinib; Trametinib; Clinical trials;
Multiplex detection of KRAS mutations by a matrix-assisted laser desorption/ionization-time of flight mass spectrometry assay
Keywords: جهش KRAS; KRAS mutation; EGFR; RFMP; KRAS mutation testing;
Clinical and the Prognostic Characteristics of Lung Adenocarcinoma Patients with ROS1 Fusion in Comparison with Other Driver Mutations in East Asian Populations
Keywords: جهش KRAS; EGFR mutation; EML4-ALK fusion; KRAS mutation; lung adenocarcinoma; ROS1 fusion; reverse transcription-polymerase chain reaction
KRAS-G12C Mutation Is Associated with Poor Outcome in Surgically Resected Lung Adenocarcinoma
Keywords: جهش KRAS; KRAS mutation; Lung adenocarcinoma; Prognostic markers;
Subtype-specific KRAS mutations in advanced lung adenocarcinoma: A retrospective study of patients treated with platinum-based chemotherapy
Keywords: جهش KRAS; Non-small cell lung cancer; Advanced-stage lung adenocarcinoma; Platinum-based chemotherapy; KRAS mutation;
Reliability of EGFR and KRAS mutation analysis on fine-needle aspiration washing in non-small cell lung cancer
Keywords: جهش KRAS; Non-small cell lung cancer; EGFR mutation; KRAS mutation; Cytology; Fine-needle aspiration; Mutation analysis;
The KRAS mutation detection within the initial management of patients with metastatic colorectal cancer: A status report in France in 2011
Keywords: جهش KRAS; Anti-EGFR; Monoclonal antibody; Genotyping; KRAS mutation; Colorectal cancer;
Distribution of KRAS and BRAF mutations in Moroccan patients with advanced colorectal cancer
Keywords: جهش KRAS; BRAF mutation; KRAS mutation; Colorectal cancerMutation du BRAF; Mutation du KRAS; Cancer colorectal
Concurrent Molecular Alterations in Tumors With Germ Line Epidermal Growth Factor Receptor T790M Mutations
Keywords: جهش KRAS; Concurrent mutations; Familial lung cancer; Germline EGFR mutations; KRAS mutation; Lung cancer prevention;
The KRAS StripAssay for detection of KRAS mutation in Egyptian patients with colorectal cancer (CRC): A pilot study
Keywords: جهش KRAS; Colorectal cancer; KRAS mutation; KRAS StripAssay
Stage III & IV colon and rectal cancers share a similar genetic profile: a review of the Oregon Colorectal Cancer Registry
Keywords: جهش KRAS; Colorectal cancer; BRAF mutation; KRAS mutation; MET mutation; NRAS mutation; PIK3CA mutation
The prognostic value of KRAS mutated plasma DNA in advanced non-small cell lung cancer
Keywords: جهش KRAS; Non-small cell lung cancer; NSCLC; Prognostic marker; KRAS mutation; Plasma KRAS; EGF system
The dominant role of G12C over other KRAS mutation types in the negative prediction of efficacy of epidermal growth factor receptor tyrosine kinase inhibitors in non–small cell lung cancer
Keywords: جهش KRAS; KRAS mutation; non–small cell lung cancer; targeted treatment of NSCLC; EGFR tyrosine kinase inhibitors; predictive factor
Influence of anatomical subsite on the incidence of microsatellite instability, and KRAS and BRAF mutation rates in patients with colon carcinoma
Keywords: جهش KRAS; Colon carcinoma; Colonic subsite; MSI; KRAS mutation; BRAF mutation
Treatment Decisions After Diagnosis of Metastatic Colorectal Cancer
Keywords: جهش KRAS; Bevacizumab; Cetuximab; First-line treatment; KRAS mutation; Panitumumab
Impact of Systematic EGFR and KRAS Mutation Evaluation on Progression-Free Survival and Overall Survival in Patients with Advanced Non–Small-Cell Lung Cancer Treated by Erlotinib in a French Prospective Cohort (ERMETIC Project—Part 2)
Keywords: جهش KRAS; Non–small cell lung cancer; Tyrosine kinase inhibitor treatment; Epidermal growth factor mutation; KRAS mutation; Prognostic factor; Prospective cohort
EGFR and KRAS mutations in metastatic lung adenocarcinomas
Keywords: جهش KRAS; EGFR mutation; KRAS mutation; Metastatic non–small cell lung cancer; Lung adenocarcinoma
Detection of DNA mutations by fluorescence resonance energy transfer-based preferential homoduplex formation assay
Keywords: جهش KRAS; Competitive hybridization; KRAS mutation; PHFA; FRET