
A C-terminally amidated analogue of ShK is a potent and selective blocker of the voltage-gated potassium channel Kv1.3
Keywords: TEM, effector memory T-cells; Kv, voltage-gated K+ channel; ShK, K+ channel toxin from Stichodactyla helianthus; ShK-amide, C-terminally amidated ShK; ShK-K-amide, ShK with a C-terminal Lys and amide; MD, molecular dynamics; PMF, potential of mean forceSh