Keywords: کینورینین; VNS; Pediatric; Therapy-resistant seizures; Tryptophan metabolic pathway; Kynurenine; Anthranilic acid;
مقالات ISI کینورینین (ترجمه نشده)
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Keywords: کینورینین; Indoleamine 2,3-dioxygenase; Depressive symptoms; Depression; Tryptophan; Kynurenine; Inflammation
Keywords: کینورینین; Protein drug substance color; N-formylkynurenine; Kynurenine; CHO cell culture; Chemically defined media; Iron
Keywords: کینورینین; Neurodevelopment; Postnatal; Kynurenine; Immune activation; Schizophrenia; Amphetamine; Locomotor activity; Prepulse inhibition; Microdialysis
Keywords: کینورینین; NET; neutrophil extracellular trap; IDO; indoleamine 2,3-dioxygenase; CF; cystic fibrosis; CGD; chronic granulomatous disease; ROS; reactive oxygen species; RLU; relative luminescence unit; CFU; colony-forming unit; AhR; aryl hydrocarbon receptor; HRPO; h
Keywords: کینورینین; IDO; Myelodysplastic syndrome; Kynurenine; Tryptophan; Hematopoiesis;
Keywords: کینورینین; 5-HIAA; 5 hydroxyindoleacetic acid; 5-HT; serotonin; 5-HTT; 5-HT transporter; ACTH; adrenocorticotropic hormone; AIAQ; anger irritability and assault questionnaire; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; BCG; bacille Calmette-Gueri
Keywords: کینورینین; Resveratrol; IDO; Immunomodulation; Tryptophan; Kynurenine
Keywords: کینورینین; Cervical cancer; IDO; Kynurenine; Tryptophan; HPLC
Keywords: کینورینین; Major depressive disorder; Magnetic resonance imaging; Medial prefrontal cortex; Quinolinic acid; Inflammation; Kynurenine
Keywords: کینورینین; Depression; Inflammation; Serotonin; Tryptophan; Kynurenine; Indoleamine 2,3-dioxygenase
Kynurenine pathway changes in late-life depression with memory deficit
Keywords: کینورینین; Late-life depression; Memory deficit; Tryptophan; Kynurenine; Kynurenic acid;
Development of a series of novel o-phenylenediamine-based indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors
Keywords: کینورینین; Indoleamine 2,3-dioxygenase; IDO; IDO1; Immuno-oncology; Kynurenine;
Simultaneous determination of tryptophan, kynurenine, kynurenic acid and two monoamines in rat plasma by HPLC-ECD/DAD
Keywords: کینورینین; Tryptophan; Kynurenine; Kynurenic acid; Depression; HPLC-ECD/DAD;
The anti-inflammatory effect of LMWF5A and N-acetyl kynurenine on macrophages: Involvement of aryl hydrocarbon receptor in mechanism of action
Keywords: کینورینین; NAT; N-acetyl tryptophan; KYN; kynurenine; NAK; N-acetyl kynurenine; HSA; human serum albumin; LMWF5A; low molecular weight fraction of 5% albumin; ESI+; electrospray positive ionization; LCMS; liquid chromatography-mass spectrometry; AhR; aryl hydrocarbo
Cyclic analogue of S-benzylisothiourea that suppresses kynurenine production without inhibiting indoleamine 2,3-dioxygenase activity
Keywords: کینورینین; Kynurenine; Inhibitor; Indoleamine 2; 3-Dioxygenase; Signal transducer and activator of transcription 1; Immunological cancer treatment;
4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy
Keywords: کینورینین; Indoleamine 2,3-dioxygenase; Inhibitor; 4-Bromophenylhydrazinyl benzenesulfonylphenylurea; In vivo target inhibition; Tryptophan; Kynurenine; Anti-tumor;
Aging exacerbates cognitive and anxiety alterations induced by an intracerebroventricular injection of amyloid-β1-42 peptide in mice
Keywords: کینورینین; Alzheimer's disease; Aging; Neuroinflammation; Indoleamine-2,3-dyoxigenase; Kynurenine; Memory; Depression; Anxiety;
Kynurenine pathway changes in late-life depression
Keywords: کینورینین; Late-life depression; Tryptophan; Kynurenine; Kynurenic acid;
Indoleamine 2,3-Dioxygenase 1, Increased in Human Gastric Pre-Neoplasia, Promotes Inflammation and Metaplasia in Mice and Is Associated With Type II Hypersensitivity/Autoimmunity
Keywords: کینورینین; Kynurenine; Gastritis; SPEM; Humoral Immunity; EBV; Epstein-Barr virus; FACS; fluorescence-activated cell sorting; IDO1; indoleamine-2,3-dioxygenase-1; IFN; interferon; MDSC; myeloid-derived suppressor cell; mRNA; messenger RNA; NK; natural killer; PE; ph
Bioenergetics and synaptic plasticity as potential targets for individualizing treatment for depression
Keywords: کینورینین; Bioenergetics; Stress; Inflammation; Metabolism; Kynurenine; Major depressive disorder (MDD); Bipolar disorder (BD); Proinflammatory cytokine; Hypothalamic-pituitary-adrenal axis (HPA axis); Brain-derived neurotrophic factor (BDNF); Mammalian target of ra
Kynurenine pathway metabolism and the neurobiology of treatment-resistant depression: Comparison of multiple ketamine infusions and electroconvulsive therapy
Keywords: کینورینین; Depression; Ketamine; Cortisol; Immune; Cytokine; Kynurenine;
Probing the structure-function relationship of Mycobacterium leprae HSP18 under different UV radiations
Keywords: کینورینین; sHSP; small heat shock protein; DTT; dithiothreitol; IPTG; isopropyl-β-d-thiogalactoside; bis-ANS; 4,4â²-dianilino-1,1â²-binaphthyl-5,5â²-disulfonic acid, dipotassium salt; NFK; N-formyl kynurenine; Kyn; Kynurenine; Mycobacterium leprae HSP18; Small h
Linking the biological underpinnings of depression: Role of mitochondria interactions with melatonin, inflammation, sirtuins, tryptophan catabolites, DNA repair and oxidative and nitrosative stress, with consequences for classification and cognition
Keywords: کینورینین; Major depressive disorder; Oxidative and nitrosative stress; Kynurenine; Aryl hydrocarbon; Immune-inflammation; Mitochondria; Pathophysiology; Melatonin; Treatment; Classification; Cognition; 3-OH-ANA; 3-hydroxyanthranillic acid; 3-OH-Kyn; 3-hydroxykynure
Glia- and tissue-specific changes in the Kynurenine Pathway after treatment of mice with lipopolysaccharide and dexamethasone
Keywords: کینورینین; Astrocyte; Microglia; Inflammation; Stress; Kynurenine;
Depressive, anxiety and hypomanic symptoms in schizophrenia may be driven by tryptophan catabolite (TRYCAT) patterning of IgA and IgM responses directed to TRYCATs
Keywords: کینورینین; Schizophrenia; Depression; Anxiety; Immune; Inflammation; Indoleamine 2,3-dioxygenase; Kynurenine;
Naringenin protects against oxido-inflammatory aberrations and altered tryptophan metabolism in olfactory bulbectomized-mice model of depression
Keywords: کینورینین; Depression; Olfactory Bulbectomy; Naringenin; Kynurenine; Tryptophan; Serotonin;
The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitis
Keywords: کینورینین; Kynurenine; Monooxygenase; Tryptophan; Substrate; Pancreatitis;
Non-tumor cell IDO1 predominantly contributes to enzyme activity and response to CTLA-4/PD-L1 inhibition in mouse glioblastoma
Keywords: کینورینین; IDO1; Glioma; Tryptophan; Kynurenine; Immunosuppression; IDO2; TDO2;
5-Hydroxytryptophan, a major product of tryptophan degradation, is essential for optimal replication of human parainfluenza virus
Keywords: کینورینین; Tryptophan; ISG; Paramyxovirus; Parainfluenza virus; IDO; 5-HTP; Serotonin; Melatonin; Kynurenine;
Identification and optimization of a novel series of indoleamine 2,3-dioxygenase inhibitors
Keywords: کینورینین; IDO; Kynurenine; Indoleamine 2,3-dioxygenase; Immuno-oncology;
Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors activate the aryl hydrocarbon receptor
Keywords: کینورینین; 1MDT; 1-Methy-D-Tryptophan; 1MLT; 1-Methyl-l-Tryptophan; AHR; Aryl Hydrocarbon Receptor; DMSO; dimethylsulfoxide; DPBS; Dulbecco's Phosphate Buffered Saline; IDO; indoleamine 2,3-dioxygenase; INCB; INCB024360; Kyn; kynurenine; KA; kynurenic acid; NLG; NLG
AHR toxicity and signaling: Role of TIPARP and ADP-ribosylation
Keywords: کینورینین; Aryl hydrocarbon receptor; 2,3,7,8-Tretrachlorodibenzo-p-dioxin; ADP-ribosylation; TCDD-inducible poly-ADP-ribose polymerase; AHR; aryl hydrocarbon receptor; AHRE; AHR response element; ARH; ADP-ribosyl hydrolases; ARNT; AHR nuclear translocator; ARTD; AD
L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences
Keywords: کینورینین; Kynurenine pathway; Indoleamine 2,3-dioxygenase; Kynurenine 3-monooxygenase; Kynurenine aminotransferase; Kynurenine; Kynurenic acid; Quinolinic acid; TRP; l-tryptophan; KP; kynurenine pathway; NAD+; nicotinamide adenine nucleotide; TDO; tryptophan 2,3-di
Kynurenine pathway metabolism and immune activation: Peripheral measurements in psychiatric and co-morbid conditions
Keywords: کینورینین; Kynurenine; Interferon-gamma; Tryptophan; Serotonin; Immune activation; Depression;
Kynurenine pathway metabolism and the microbiota-gut-brain axis
Keywords: کینورینین; Tryptophan; Kynurenine; Stress; Immune system; Microbiota-gut-brain-axis; Behaviour; BBB; blood brain barrier; CNS; central nervous system; DSM; diagnostic and statistical manual; ENS; enteric nervous system; GABA; gamma-aminobutyric acid; GF; germfree; G
Microbial regulation of hippocampal miRNA expression: Implications for transcription of kynurenine pathway enzymes
Keywords: کینورینین; Microbiota; microRNA; Hippocampus; Kynurenine; Germ-free; Sex;
Characterization of N-Acetyl-Tryptophan Degradation in Protein Therapeutic Formulations
Keywords: کینورینین; HPLC (high-performance/pressure liquid chromatography); oxidation; excipients; chemical stability; formulation; analytical chemistry; AAPH; 2,2â²-Azobis(2-amidinopropane) dihydrochloride; DiOia; dioxyindolylalanine; HSA; human serum albumin; ICH; Interna
Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain
Keywords: کینورینین; 3-HK; 3-hydroxy-kynurenine; FST; forced swim test; HAAO; 3-hydroxyanthralinic acid dioxygenase; i.c.v; intracerebroventricular; IDO; indoleamine 2,3-dioxygenase; IL; interleukin; KMO; kynurenine 3-monooxygenase; KYN; kynurenine; KYNA; kynurenic acid; KYNU
Glial and tissue-specific regulation of Kynurenine Pathway dioxygenases by acute stress of mice
Keywords: کینورینین; Stress; Ido; Tdo; Kynurenine; Astrocyte; Liver;
Augmentation of antidepressant effects of venlafaxine by agomelatine in mice are independent of kynurenine pathway
Keywords: کینورینین; Agomelatine; Venlafaxine; Chronic forced swim test; Tail suspension test; Kynurenine; Tryptophan
Analysis of amino acids in human blood using UHPLC-MS/MS: Potential interferences of storage time and vacutainer tube in pre-analytical procedure
Keywords: کینورینین; AA; amino acid; KIM-1; kidney injury molecule-1; NGAL; neutrophil gelatinase-associated lipocalin; Ala; alanine; Met; methionine; Trp; tryptophan; Ile; isoleucine; Leu; leucine; CLSI; Clinical and Laboratory Standards Institute; Ser; serine; Cys; cysteine
Burkholderia pseudomallei kynB plays a role in AQ production, biofilm formation, bacterial swarming and persistence
Keywords: کینورینین; Kynurenine; Anthranilate; Virulence factors; Antibiotic tolerance; Quorum sensing;
LC/MS-based metabolomics strategy to assess the amelioration effects of ginseng total saponins on memory deficiency induced by simulated microgravity
Keywords: کینورینین; Ach; acetylcholine; AD; Alzheimer's disease; Asn; asparagine; Asp; aspartic acid; BC; behavioral research control group; BH; behavioral research HU group; BHG; behavioral research HU plus GTS treatment group; CORT; corticosterone; DA; dopamine; DHBA; dihy
Multiprobe molecular imaging of an NMDA receptor hypofunction rat model for glutamatergic dysfunction
Keywords: کینورینین; BPnd; non-displacable binding potential; CG; cingulate cortex; CP; caudate putamen; CT; computed tomography; Ctrl; control; Ctrl-PBO; placebo-treated control cohort; Ctrl-NAc; NAc-treated control cohort; FOV; field of view; GSH; glutathion; HC; hippocampu
Kynurenine pathway metabolism following prenatal KMO inhibition and in Mecp2+/â mice, using liquid chromatography-tandem mass spectrometry
Keywords: کینورینین; Kynurenine; Kynurenic acid; Quinolinic acid; Tryptophan metabolism; Rett syndrome;
The novel KMO inhibitor CHDI-340246 leads to a restoration of electrophysiological alterations in mouse models of Huntington's disease
Keywords: کینورینین; Kynurenine; Kynurenic acid; Inhibitor; Huntington's disease; Quinolinic acid; Pharmacodynamic; Neurodegeneration; Q175; R6/2;
Kynurenine causes vasodilation and hypotension induced by activation of KCNQ-encoded voltage-dependent K+ channels
Keywords: کینورینین; Hypotension; Kynurenine; Vasodilation; Voltage-dependent K+ channels encoded by the KCNQ gene family
Neuropeptide Y administration reverses tricyclic antidepressant treatment-resistant depression induced by ACTH in mice
Keywords: کینورینین; Serotonin; Hypothalamic-pituitary-adrenocortical; Kynurenine; Neurotrophins; BDNF; Indoleamine 2,3-dioxygenase;
The aryl hydrocarbon receptor (AhR) mediates resistance to apoptosis induced in breast cancer cells
Keywords: کینورینین; AhR; aryl hydrocarbon receptor; ER; estrogen receptor; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; MNF; 3â²methyl-4â²nitroflavone; COX-2; cyclooxygenase-2; IDO; indoleamine 2, 3-dioxygenase; Kyn; kynurenine; MNF; 3â²methoxy-4â²nitroflavone; TGFα; tran