Keywords: Merlin; Conformation; Phosphorylation; Lats2; Cell proliferation;
مقالات ISI (ترجمه نشده)
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Hypermethylated LATS2 gene with decreased expression in female breast cancer: A case control study from North India
Keywords: LATS2; Large associated tumor suppressor 2; YAP; Yes associated Protein; Real time PCR; MS PCR (methylation specific PCR); Immunohistochemistry; Tumor biomarkers;
MiR-93-5p promotes gastric cancer-cell progression via inactivation of the Hippo signaling pathway
Keywords: GC; Gastric cancer; FAT4; Protocadherin Fat 4; LATS2; Large tumor suppressors 2; CDX2; Caudal-related homeobox transcription factor; FOXM1; Fork head box M1; CTGF; Connective tissue growth factor; CYR61; Cysteine-rich angiogenic inducer 61; RUNX3; Runt-re
Engineered exosomes: A new promise for the management of musculoskeletal diseases
Keywords: Engineered exosomes; Drug delivery; Musculoskeletal diseases; Regenerative medicine; Oncology; Immune system regulation; 3â²UTR; 3â²untranslated regions; 6-OHDA; 6-hydroxydopamine; APC; adenomatous polyposis coli; BRD7; bromo-domain-containing protein 7
Deubiquitylating enzymes as cancer stem cell therapeutics
Keywords: Protein-IPSC; protein-induced pluripotent stem cells; CSCs; cancer stem cells; DUBs; deubiquitylating enzymes; ESCs; embryonic stem cells; PTMs; post-translational modifications; AML; acute myelogenous leukemia; USP/UBP; ubiquitin-specific processing prot
The Hippo pathway in normal development and cancer
Keywords: BC; breast cancer; CRC; colorectal cancer; CSCs; cancer stem cells; EMT; epithelial-mesenchymal transition; GPCRs; G-protein-coupled receptors; HCC; hepatocellular carcinoma; LATS1; large tumor suppressor 1; LATS2; large tumor suppressor 2; MOB1A; MOB kin
DDK Promotes Tumor Chemoresistance and Survival via Multiple Pathways
Keywords: DDK; DBF4-dependent kinase; LATS2; large tumor suppressor kinase 2; TCGA; The Cancer Genome Atlas;
Original ArticleA miR-135b-TAZ positive feedback loop promotes epithelial-mesenchymal transition (EMT) and tumorigenesis in osteosarcoma
Keywords: OS; TAZ; microRNA; LATS2; APC; GSK-3β; Tumorigenesis;
The characterisation of LATS2 kinase regulation in Hippo-YAP signalling
Keywords: LATS2; large tumour suppressor 2; MST1/2; mammalian serine/threonine Ste20-like kinases 1/2; MOB; Mps one binder; NDR; nuclear Dbf2-related; NTR; N-terminal regulatory region; HM; hydrophobic motif; PIF; PDK1-interacting fragment; PRK2; PKC related kinase
Sphingosylphosphorylcholine regulates the Hippo signaling pathway in a dual manner
Keywords: Sphingosylphosphorylcholine; Lats2; Yap; S1P2; Proliferation;
miR-107 and miR-25 simultaneously target LATS2 and regulate proliferation and invasion of gastric adenocarcinoma (GAC) cells
Keywords: Gastric adenocarcinoma; miR-107; miR-25; LATS2;
Expression of LATS family proteins in ovarian tumors and its significance
Keywords: Ovarian serous tumors; Ovarian mucinous tumors; Clear cell carcinoma; LATS1; LATS2
MicroRNA-181b promotes ovarian cancer cell growth and invasion by targeting LATS2
Keywords: miR-181b; LATS2; Ovarian cancer; Proliferation; Invasion;
A review of the current understanding and clinical utility of miRNAs in esophageal cancer
Keywords: miRNA/miR; MicroRNA [ribonucleic acid]; EAC; Esophageal adenocarcinoma; BE; Barrett's esophagus; LGD; Low grade dysplasia; HGD; High grade dysplasia; ESCC; Esophageal squamous cell carcinoma; NE; Normal epithelium; qRT-PCR; Quantitative reverse transcript
Mechanism of folate deficiency-induced apoptosis in mouse embryonic stem cells: Cell cycle arrest/apoptosis in G1/G0 mediated by microRNA-302a and tumor suppressor gene Lats2
Keywords: mESCs; mouse embryonic stem cells; hESCs; human embryonic stem cells; GO; gene ontology; FDR; false discovery rate; ECCs; embryonic carcinoma cells; iPSCs; induced pluripotent stem cells; Folate deficiency; miR-302a; Apoptosis; Cell cycle; Lats2;
p53: Guardian of ploidy
Keywords: Aneuploidy; Tetraploidy; p53; Lats2; Genomic instability; Oncogenic H-Ras;
Identification of LATS transcriptional targets in HeLa cells using whole human genome oligonucleotide microarray
Keywords: CTP, cytidine triphospate; LATS, Large Tumor Suppressor; MEFs, mouse embryonic fibroblasts; siRNA, small-interfering RNA; qRT-PCR, quantitative reverse transcriptase polymerase chain reactionLATS1; LATS2; Microarray; Tumor suppressor; Cell proliferation;
LATS2 tumour specific mutations and down-regulation of the gene in non-small cell carcinoma
Keywords: LATS2; NSCLC; P53; K-RAS; MDM2; Mutation; Squamous; RT-PCR
MicroRNA-373 (miR-373) post-transcriptionally regulates large tumor suppressor, homolog 2 (LATS2) and stimulates proliferation in human esophageal cancer
Keywords: miRNA, microRNA; LATS2, large tumor suppressor, homolog 2; ESCC, esophageal squamous cell carcinoma; RT-PCR, reverse transcription-polymerase chain reaction; pre-miR, precursor microRNA; miCHIP, miRNA chipEsophageal cancer; LATS2; MicroRNA; MiR-373; Proli
LATS2–Ajuba complex regulates γ-tubulin recruitment to centrosomes and spindle organization during mitosis
Keywords: CIAP, calf intestine alkaline phosphatase; GST, glutathione-S-transferase; MEF, mouse embryonic fibroblast; RNAi, RNA interference; siRNA, short interference RNA; γ-TuRC, γ-tubulin ring complexMitosis; LATS2; Ajuba; Centrosome; Spindle organization
Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma
Keywords: Astrocytoma; LATS1; LATS2; Methylation; Methylation-specific PCR (MSP)