دانلود مقالات ISI درباره Lgic + ترجمه فارسی

مجتمع های پروتئینی به عنوان اهداف دارویی روانپزشکی و عصبی

Protein complexes as psychiatric and neurological drug targets

Keywords: AM; adrenomedulin; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMY; amylin; AT; angiotensin type; β-CCT; beta-carboline-3-carboxylate-t-butyl ester; CT; calcitonin; CTR; calcitonin receptor; CLR; calcitonin receptor-like receptor; DZ; di

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2018 سفارش ترجمه

مس و پروتون به طور مستقیم کانال فعال روی را فعال می کند

Copper and protons directly activate the zinc-activated channel

Keywords: ZAC; zinc-activated channel; LGIC; ligand-gated ion channel; nACh; nicotinic acetylcholine; 5-HT; 5-hydroxytryptamine; GFP; green fluorescent protein; MOPS; 10 3-(N-morpholino)propanesulfonic acid; CTR1; high affinity copper uptake protein 1; GLIC; Gloeob

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

پیگیری پروتئین غشای فردی و بیوشیمی آنها: توانایی مشاهده مستقیم

Tracking individual membrane proteins and their biochemistry: The power of direct observation

Keywords: Single molecule fluorescence imaging; Protein tracking; P2X1; 5HT3; Fluorescence; LGIC; Ligand-gated ion channel; GPCR G-protein coupled receptor; Molecular machine; Stochastic;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

اثرات لیودو کایین بر جریان استیل کولین از مویرگ های نورون گانگلیون سرویکس

Lidocaine effects on acetylcholine-elicited currents from mouse superior cervical ganglion neurons

Keywords: ACh; acetylcholine; IACh; acetylcholine-elicited current; LA; local anaesthetic; LGIC; ligand-gated ion channel; nAChR; nicotinic acetylcholine receptor; QX-222; 2-(trimethylammonio)-N-(2,6-dimethylphenyl) acetamide chloride; QX-314; 2-(triethylammonio)-N

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Auxiliary subunits of AMPA receptors: The discovery of a forebrain-selective antagonist, LY3130481/CERC-611

Keywords: ABHD6; alpha/beta-hydrolase domain-containing protein 6; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionate; CKAMP; cystine-knot AMPAR modulating protein; CNIH; cornichon; CPT1c; carnitine palmitoyltransferase 1C; FRRS1L; ferric chelate reductase 1-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

GABAA receptor: Positive and negative allosteric modulators

Keywords: γ-Aminobutyric acid type A receptors; Inhibitory neurotransmission; CNS depressant drug target; Anxiolytics/sedatives/general anesthetics; Ethanol; GABA; γ-aminobutyric acid; GABAAR; GABAA receptors; LGIC; ligand-gated ion channels; PLGIC; pentameric LG

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Molecular characterization and expression pattern of three GABA receptor-like subunits in the small brown planthopper Laodelphax striatellus (Hemiptera: Delphacidae)

Keywords: GABA; γ-aminobutyric acid; LGIC; ligand-gated ion channel; TM; transmembrane; nAchR; nicotinic acetylcholine receptor; GPCR; G protein-coupled receptor; RDL; resistance to dieldrin; LCCH3; ligand-gated chloride channel homolog 3; GRD; GABA and glycine re

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells

Keywords: Neural induction; Neural progenitor cells; hiPSC; Electron microscopy; Patch clamp; 2D-3D neural induction; AD; Alzheimer's disease; AQP4; Aquaporin 4; ASD; Autism spectrum disorder; bFGF; Basic Fibroblast Growth Factor; CNS; Central Nervous System; D; Da

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

The antidepressant bupropion is a negative allosteric modulator of serotonin type 3A receptors

Keywords: Antidepressant; Bupropion; Hydroxybupropion; 5-HT3A receptors; Pentameric ligand-gated ion channels; 5-HT3AR; 5-hydroxytryptamine type 3A receptor; 5-HT; 5-hydroxytryptamine; ACh; acetylcholine; α-BgTx; α-bungarotoxin; CNS; central nervous system; DA; d

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

GABAA receptor-mediated neurotransmission: Not so simple after all

Keywords: GABA; γ-amino-butyric acid; LGIC; ligand gated ion channel; cAMP; cyclic AMP; 5HT3; 5-hydroxy-triptamine receptor; PKA; protein kinase A; AIS; axon initial segment; CCC; cations chloride cotransporter; NKCC; sodium potassium chloride cotransporter; NCC;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Molecular mechanisms of LL-37-induced receptor activation: An overview

Keywords: AMP; antimicrobial peptide; APD; antimicrobial peptide database; IFN; interferon; DC; dendritic cell; NK-cells; natural killer cells; GPCR; G protein-coupled receptor; RTK; receptor tyrosine kinase; LGIC; ligand-gated ion channel; TLR; toll-like receptor;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

A parallel panning scheme used for selection of a GluA4-specific Fab targeting the ligand-binding domain

Keywords: GPCR; G-protein coupled receptor; LGIC; ligand-gated ion-channels; VGIC; voltage-gated ion-channels; mAb; monoclonal-antibody; Fab; fragment antigen binding; ELISA; enzyme-linked immunosorbent assay; Glu; glutamate; AMPA receptor; (S)-2-amino-3-(3-hydroxy

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2016 سفارش ترجمه

Invited reviewInvestigating ion channel conformational changes using voltage clamp fluorometry

Keywords: Fluorescence; Voltage clamp; Ion channel; Conformational change; Protein structure; 6TM; 6 transmembrane; fUAA; fluorescent unnatural amino acid; GABAAR; GABA A-type receptor; GlyR; glycine receptor; LGIC; ligand-gated ion channel; MTS; methanethiosulphon

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The coupling interface and pore domain codetermine the single-channel activity of the α7 nicotinic receptor

Keywords: Nicotinic receptor; Patch-clamp; Channel gating; Channel coupling; nAChR; nicotinic acetylcholine receptor; ACh; acetylcholine; α-BTX; alpha-bungarotoxin; LGIC; ligand-gated ion channel; 5-HT3R; serotonin receptor type 3; GABAR; γ-aminobutyric acid rece

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Flexible subunit stoichiometry of functional human P2X2/3 heteromeric receptors

Keywords: Heteromeric P2X receptors; P2X2/3 receptors; Subunit stoichiometry; Mutagenesis; 2-MeSATP; 2-methylthio ATP; ASIC; acid-sensing ion channel; BN-PAGE; blue native PAGE; DRG; dorsal root ganglion; EC50; half maximal effective concentration; FR; fluorescent

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Characterization of cys-loop receptor genes involved in inhibitory amine neurotransmission in parasitic and free living nematodes

Keywords: LGIC; ligand-gated ion channel; LGCC; ligand-gated chloride channel; nAChR; nicotinic acetylcholine receptor; cDNA; copy DNA; RT-PCR; reverse-transcription polymerase chain reaction; RACE; rapid amplification of cDNA ends; TM; transmembrane; bp; base pair

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

N3,N7-diaminophenothiazinium derivatives as antagonists of α7-nicotinic acetylcholine receptors expressed in Xenopus oocytes

Keywords: ACh; acetylcholine; BAPTA; 1,2-bis(o-aminophenoxy) ethane-N,N,N′,Nv-tetraacetic acid; HEPES; 4-(2-hydroxyethyl) piperazineethanesulfonic acid; LGIC; ligand-gated ion channel; nAChR; nicotinic acetylcholine receptor; Phenothiazines; Diaminophenothiaziniu

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Chemotography for multi-target SAR analysis in the context of biological pathways

Keywords: GPCR; G-protein coupled receptor; LGIC; ligand-gated ion channel; SAR; structure-activity relationship; Chemical space; Color; Visualization; Molecular fingerprints; Chemogenomics; Systems pharmacology; Molecular pathways;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

The Haemonchus contortus UNC-49B subunit possesses the residues required for GABA sensitivity in homomeric and heteromeric channels

Keywords: 5-HT3; serotonin (5-hydroxytryptamine)-gated ion channel receptor; AChBP; acetylcholine binding protein; cRNA; copy RNA; LGIC; ligand-gated ion channels; MS-222; 3-aminobenzoic acid ethyl ester, methanesulphonate salt; nAChR; nicotinic acetylcholine recep

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Allosteric modulators induce distinct movements at the GABA-binding site interface of the GABA-A receptor

Keywords: GABAA receptor; Benzodiazepine efficacy; Oocyte expression; Allosteric modulation; Pentobarbital; GABA; BZD; benzodiazepine; GABAR; GABA-A receptor; MTSEA-Biotin; N-biotinaminoethyl methanethiosulfonate; MTSES; 2-sulfonatoethyl methanethiosulfonate; DMCM;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Characterization of a novel tyramine-gated chloride channel from Haemonchus contortus

Keywords: BP; base pairs; cDNA; copy DNA; LGCC; ligand-gated chloride channel; LGIC; ligand-gated ion channel; ML; macrocyclic lactone; RACE; rapid amplification of cDNA ends; SL; spliced leader; SNP; single nucleotide polymorphism; UTR; untranslated region; qRT-PC

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Functional impact of serial deletions at the C-terminus of the human GABAρ1 receptor

Keywords: GFP; LGIC; TM4; Site-directed mutagenesis; Xenopus oocytes

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Importance of the C-terminus of the human 5-HT3A receptor subunit

Keywords: LGIC; 5-HT3A receptor 5-HT3A receptor subunit; C-terminus; Protein folding and stability; HEK; human embryonic kidney; LGIC; ligand-gated ion channel; nAChR; nicotinic acetylcholine receptor; 5-HT; 5-hydroxytryptamine;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Regulatory molecules for the 5-HT3 receptor ion channel gating system

Keywords: 5-HT3 receptor; LGIC; Partial agonist; Ion channels; Molecular modeling

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه