Keywords: Nitro compounds; Natural products; Pharmaceuticals; Stereoselective synthesis; Organocatalysis; Metal catalysis; Nitronates; Nitrile oxides; AIBN; azobisisobutyronitrile; AZADO; 2-azaadamantane-N-oxyl; 9-BBN; 9-borabicyclo[3.3.1]nonane; BINAP; 2,2â²-bis(
مقالات ISI (ترجمه نشده)
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Keywords: Ac; acetyl; acac; acetylacetonate; 9-BBN; 9-borabicyclo[3.3.1]nonane; Bn; benzyl; Boc; tert-butyloxycarbonyl; BOM; benzyloxymethyl; brsm; based on recovered starting material; Bz; benzoyl; CAN; ammonium cerium(IV) nitrate; Cbz; benzyloxycarbonyl; CD; circ
Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors
Keywords: HSP90; Fragment-based drug discovery; Crystallography; CDI; 1,1â²-carbonyldiimidazole; DCM; dichloromethane; DHP; 3,4-dihydro-2H-pyran; DMAP; 4-dimethylaminopyridine; DMF; N,N-dimethylformamide; LHMDS; lithium hexamethyldisilazide;
Novel antiobesity agents: Synthesis and pharmacological evaluation of analogues of Rimonabant and of LH21
Keywords: LH21; 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole; Rimonabant; 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide; CB1; cannabinoid receptor 1; CB2; cannabinoid receptor 2; PPARα; perox
Stereoselective syntheses of naturally occurring 5,6-dihydropyran-2-ones
Keywords: Naturally occurring 5,6-dihydropyran-2-ones; 5,6-Dihydro-α-pyrones; Stereoselective synthesis; Ad; adamantyl; BINAP; 2,2â²-bis(diphenylphosphino)-1,1â²-binaphthalene; BINOL; 1,1â²-bi(2-naphthol); B.Y.; baker's yeast; Bn; benzyl; Bz; benzoyl; Car; 2-ca
Recent advances and applications in 1,2,4,5-tetrazine chemistry
Keywords: Ac; acetyl; Ar; aryl; Bn; benzyl; Boc; tert-butoxycarbonyl; Bu; butyl; Bz; benzoyl; CBz; benzylcarboxy; DABCO; 1,4-diazabicyclo[2.2.2]octane; DBU; 1,8-diazabicyclo[5.4.0]undec-7-ene; DDQ; 2,3-dichloro-5,6-dicyano-1,4-benzoquinone; DMA; N,N-dimethylacetami
LHMDS mediated tandem acylation-cyclization of 2-aminobenzenecarbonitriles with 2-benzymidazol-2-yl acetates: a short and efficient route to the synthesis of 4-amino-3-benzimidazol-2-ylhydroquinolin-2-ones
Keywords: Receptor tyrosine kinases (RTK); 4-Amino-3-benzimidazol-2-ylhydroquinolin-2-one; Tandem acylation-cyclization; LHMDS;
An efficient stereoselective preparation of cis-perfluoroalkenylzinc reagents [(E)-RFCFCFZnCl] by the metallation of 1H,1H-perfluoroalkanes and their derivatization to cis-1-arylperfluoroalkenes [(Z)-RFCFCFAr]
Keywords: 1H,1H-Perfluoroalkanes; 1-Arylperfluoroalkenes; Perfluoroalkenylzinc; 1-Iodoperfluoroalkenes; LHMDS; Dehydrofluorination; Pd(0) coupling
Synthesis of amino- and diaminoconduritols and their applications
Keywords: Conduritols; Conduramines; Diaminoconduritols; Asymmetric synthesis; Ac; acetyl; aq; aqueous; AIBN; 2,2â²-azobis(isobutyronitrile); Bn; benzyl; Boc; tert-butyloxycarbonyl; n-Bu; n-butyl; s-Bu; sec-butyl; t-Bu; tert-butyl; Bz; benzoyl; CAN; ceric ammonium
Use of chiral sulfoxides in asymmetric synthesis
Keywords: Ac; acetyl; Acac; acetylacetone; AIBN; 2,2â²-azobisisobutyronitrile; Ar; aryl; BF3·Et2O; boron trifluoride etherate; BINAP; 2,2â²-bis(diphenylphosphanyl)-1,1â²-binaphthyl; Bn; benzyl; Boc; tert-butoxycarbonyl; Born; borneol; Bu; butyl; Cbz; benzyloxyc
An efficient dehyrohalogenation method for the synthesis of α,β,β-trifluorostyrenes, α-chloro-β,β-difluorostyrenes and E-1-arylperfluoroalkenes
Keywords: 1,2,2-Trifluorostyrene; 1-Chloro-2,2-difluorostyrene; 1-Arylperfluoroalkene; 1-Aryl-1,2,2,2-tetrafluoroethane; 1-Chloro-1-aryl-2,2,2-trifluoroethane; Dehydrofluorination; Dehydrohalogenation; Trifluoromethylketone; LHMDS; DAST;
Synthetic approaches to the 2012 new drugs
Keywords: 1,2-DAP; 1,2-diaminopropane; 1,2-DCE; 1,2-dichloroethane; Ac; acetyl; aq; aqueous; B2(pin)2; bis(pinacolato)diboron; BINAP; 2,2â²-bis(diphenylphosphino)-1,1â²-binaphthyl; BOP; benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophospate; CDI; N