Keywords: Dendritic spine; Synaptic plasticity; Neurodegenerative diseases; Psychiatric disorders; Glutamate receptor; Calcium signaling; ADHD; attention deficit hypersensitive disorders; FXS; Fragile X-syndrome; CNS; central nervous system; GABA; gamma amino butyr
مقالات ISI (ترجمه نشده)
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Keywords: F-actin; actin filaments; G-actin; monomeric globular actin; G-site; G-actin-binding site; TnCl; taurine chloramine; Pi; phosphate; ADF; actin-depolymerizing factor; F-site; F-actin-binding site; HOCl; hypochlorous acid; MetO; methionine sulfoxide; DM; Cy
In vitro inhibitory properties of sesquiterpenes from Chloranthus serratus on cell motility via down-regulation of LIMK1 activation in human breast cancer
Keywords: Chloranthus serratus; Motility; LIM kinase 1; Serralactone A; Breast cancer; ADF; actin depolymerizing factor; CBS; cytoskeleton buffer with sucrose; DMEM; Dulbecco's Modified Eagle Medium; FBS; fetal bovine serum; LIMK1; LIM kinase 1; SERA; serralactone
miR-51 regulates GABAergic synapses by targeting Rab GEF GLO-4 and lysosomal trafficking-related GLO/AP-3 pathway in Caenorhabditis elegans
Keywords: GABA; γ-aminobutyric acid; PTZ; pentylenetetrazole; SNB-1; Synaptobrevin 1; GEF; guaninenucleotide exchange factor; SVs; synaptic vesicles; ACh; acetylcholine; NMJs; neuromuscular junctions; miRNAs; microRNAs; GluR; glutamate receptor; nAChR; neuronal ac
LIM kinase function and renal growth: Potential role for LIM kinases in fetal programming of kidney development
Keywords: Kidney; Nephrogenesis; cofilin1; Limk1; Limk2; Mitosis; Programming;
Anti-glycan antibodies halt axon regeneration in a model of Guillain Barrè Syndrome axonal neuropathy by inducing microtubule disorganization via RhoA-ROCK-dependent inactivation of CRMP-2
Keywords: GBS; Guillain Barrè Syndrome; DRGn; dorsal root ganglion neurons; MTs; microtubules; DRG; dorsal root ganglion; GC; growth cone; CRMP-2; collapsing response mediator protein 2; intraperitoneally; IP; IgG; immunoglobulin G; tubulin GFP; green fluorescent
Overexpression of LIMK1 promotes tumor growth and metastasis in gastric cancer
Keywords: LIMK1; Gastric cancer; FAK/paxillin
AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo
Keywords: 6-OHDA; 6-hydroxydopamine; AAV; adeno-associated viral vector; Bcl-2; B-cell lymphoma 2; CNS; central nervous system; ctl; contralateral; DAPI; 4â²,6-diamidino-2-phenylindole; DIV; day in vitro; DOPAC; 3,4-dihydroxyphenylacetic acid; EGFP; enhanced green
PKA-dependent phosphorylation of LIMK1 and Cofilin is essential for mouse sperm acrosomal exocytosis
Keywords: Small GTPases; Acrosomal exocytosis; Actin; Cofilin; LIMK1; Sperm
Ubiquitin-proteasome-dependent slingshot 1 downregulation in neuronal cells inactivates cofilin to facilitate HSV-1 replication
Keywords: HSV-1; herpes simplex virus 1; F-actin; actin filaments; p-cofilin; phosphorylated cofilin; SSH1; slingshot-1; LIMK1; LIM kinase-1; HSV-1; Cofilin; SSH1; Ubiquitin-proteasome;
Reelin, neuronal polarity and process orientation of cortical neurons
Keywords: Apoer2; apolipoprotein E receptor 2; BDNF; brain-derived neurotrophic factor; cp; cortical plate; Dab1; disabled-1; EBs; end-binding proteins; ECM; extracellular matrix; GEF; Guanine nucleotide exchange factor; imz; intermediate zone; IPCs; intermediate p
Inactivation of brain Cofilin-1 by age, Alzheimer's disease and γ-secretase
Keywords: AD; Alzheimer's disease; APP; amyloid precursor protein; APP/PS1; APPKM670/671NL/PS1L166P transgenic mice; APPKO; amyloid precursor protein knockout mice; Aβ; Amyloid-β peptides; Cofilin1; Cofilin isoform 1; CpdE; Compound E; DIV; days in vitro; DMSO; d
Hippocampal subregion-specific microRNA expression during epileptogenesis in experimental temporal lobe epilepsy
Keywords: miRNAs; microRNAs; DG; dentate gyrus; PHC; parahippocampal cortex; MAPK; mitogen-activated protein kinase; TGFβ; transforming growth factor beta; mTOR; mammalian target of rapamycin; TLE; temporal lobe epilepsy; SE; status epilepticus; RIN; RNA Integrity
BDNF mechanisms in late LTP formation: A synthesis and breakdown
Keywords: Brain-derived neurotrophic factor (BDNF); TrkB signaling; Synaptic plasticity; Long-term potentiation (LTP); Protein synthesis; Translation control; Cytoskeletal dynamics; Arc; activity-regulated cytoskeleton-associated protein; AS; Angelman syndrome; AS-
BDNF-induced local protein synthesis and synaptic plasticity
Keywords: Brain-derived neurotrophic factor (BDNF); Synaptic plasticity; Long-term potentiation (LTP); Translation; RNA transport; ADF; actin-depolymerizing factor; A2RE; heterogeneous nuclear ribonucleoprotein (hnRNP) A2 response element; Arc; activity-regulated c
Epilepsy and microRNA
Keywords: Ago; Argonaute proteins; DCX; doublecortin; HMGB1; high mobility group box 1; i.c.v.; intracerebroventricular; LNA; Locked-nucleic acid; Limk1; Lim-domain containing kinase 1; miRNA; MicroRNA; RISC; RNA-induced silencing complex; TLE; temporal lobe epilep
Modulation of cofilin phosphorylation by inhibition of the Lim family kinases
Keywords: LIMK1; LIMK2; Cofilin phosphorylation; Actin cytoskeleton;
The hallmarks of CDKN1C (p57, KIP2) in cancer
Keywords: AML; acute myeloid leukemia; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma-x long; BCR-ABL; breakpoint cluster region-V-abl Abelson murine leukemia viral oncogene homolog 1; bHLH; basic helix-loop-helix; BWS; Beckwith-Wiedemann Syndrome; CDK; cy
Serine phosphorylation regulates disabled-1 early isoform turnover independently of Reelin
Keywords: ApoER2; apolipoprotein E receptor 2; CsA; cyclosporine A; Cdk; cyclin dependent kinase; Dab1; Disabled-1; CHX; cycloheximide; CPTS; 3,4',4â³,4-copper phthalocyanine tetrasulfonic acid, tetrasodium salt; CsA; cyclosporine A; ED; embryonic day; GSK3; glyco
Pathway-based genome-wide association analysis identified the importance of EphrinA-EphR pathway for femoral neck bone geometry
Keywords: PAK1; p21-activated kinase 1; FAK1; PTK2 protein tyrosine kinase 2; EphA7; Eph receptor A7; PIK3CG; phosphoinositide-3-kinase, catalytic, gamma; PAK7; p21-activated kinase 7; RASA1; RAS p21 protein activator 1; FYN; FYN oncogene related to SRC, FGR, YES;
DGCR6L, a novel PAK4 interaction protein, regulates PAK4-mediated migration of human gastric cancer cell via LIMK1
Keywords: PAK4; DGCR6L; Migration; LIMK1; F-actin;
High glucose increases phosphocofilin via phosphorylation of LIM kinase due to Rho/Rho kinase activation in cultured pig proximal tubular epithelial cells
Keywords: Cofilin; LIMK1; RhoA/Rho kinase; High glucose; PTECs
The phosphorylation of p25/TPPP by LIM kinase 1 inhibits its ability to assemble microtubules
Keywords: LIMK1; p25-TPPP; Microtubules; Phosphorylation; Expression pattern;