Keywords: سمیت لیپتو; ceramide; fatty acylcarnitine; lipotoxicity; sphingomyelin;
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Keywords: سمیت لیپتو; HA; hexadecan-1-oic (palmitic) acid; HyA; hexadec-15-yn-1-oic acid; 2-ClHDA; 2-chlorohexadecan-1-al; 2-ClHDyA; 2-chlorohexadec-15-yn-1-al; 2-ClHA; 2-chlorohexadecan-1-oic acid; 2-ClHyA; 2-chlorohexadec-15-yn-1-oic acid; Apoptosis; Blood-brain barrier; Lip
Keywords: سمیت لیپتو; FFA; free fatty acids; IHL; intrahepatic lipids; IMCL; intramyocellular lipids; RQ; respiratory Quotient; T2DM; type 2 diabetes mellitus; Lipotoxicity; Energy expenditure; Type 2 diabetes;
Keywords: سمیت لیپتو; Extracellular vesicles (EVs); Exosomes; Microparticles; Fatty liver diseases; Lipotoxicity; Non-alcoholic steatohepatitis (NASH); Alcoholic steatohepatitis (ASH);
Keywords: سمیت لیپتو; AKI; acute kidney injury; ATP5a1; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha 1; Bax; BCL2 associated X; BUN; blood urea nitrogen; CREA; serum creatinine; CC; creatinine clearance; CCK-8; cell counting kit-8; CD36; cluster of differenti
Keywords: سمیت لیپتو; Lipotoxicity; Lipids; Fatty acid metabolism; Fatty acids; Cells and tissues;
Keywords: سمیت لیپتو; Hyperglycemia; Endothelium; Lipotoxicity; ER stress; Inflammation;
Keywords: سمیت لیپتو; Sleep apnea; Sympathetic nervous system; Lipolysis; Free fatty acid; Lipotoxicity;
Keywords: سمیت لیپتو; Obesity; infertility; lipotoxicity;
Keywords: سمیت لیپتو; 4-HDDE; 4-Hydroxy-2E,6Z-dodecadienal; 4-HHE; 4-Hydroxyl-2E-hexenal, 4-HNE, 4-Hydroxy-2E-nonenal; AGE; Advanced glycation end products; ALE; Advanced lipoxidation end products; AR; aldose reductase; COX; Cyclooxygenase; EET; Epoxyeicosatrienoic acid; ER; E
Keywords: سمیت لیپتو; Triglycerides; Non-esterified fatty acids; Lipotoxicity; Type 2 diabetes;
Keywords: سمیت لیپتو; Stearic acid; Circulating angiogenic cells; Lipotoxicity; Apoptosis; Inflammation;
Keywords: سمیت لیپتو; Fatty acids; Size; Lipid metabolism; Lipotoxicity;
Keywords: سمیت لیپتو; IL-6; interleukin-6; ND; normal diet; HFD; high fat diet; FAs; fatty acids; CD36; cluster of differentiation 36; MCP-1; monocyte chemoattractant protein 1; PPARα; peroxisome proliferator-activated receptor α; CPT-1; carnitine palmitoyltransferase 1; End
Keywords: سمیت لیپتو; Diabetes; Gestational diabetes mellitus; Metabolomics; Meta-inflammation; Tryptophan metabolism; Purine metabolism; Lipotoxicity;
Keywords: سمیت لیپتو; Lipotoxicity; Lipid particles; Saccharomyces cerevisiae; Squalene synthase; Squalene monooxygenase; terbinafine; CFU; colony forming units; ER; endoplasmic reticulum; FA; fatty acids; IC50; concentration causing 50% inhibition of growth; LD; lipid droplet
Keywords: سمیت لیپتو; Insulin resistance; Fatty acid oxidation; Lipotoxicity;
Keywords: سمیت لیپتو; Obesity; Mitochondria; Endoplasmic reticulum; Lipotoxicity; Calcium; Insulin resistance;
Keywords: سمیت لیپتو; Hens; Matrix metalloproteinases; Leukocytes; Lipotoxicity; Ovulation
Keywords: سمیت لیپتو; β-AR; β-adrenergic receptor; 4-HNE; 4-hydroxynonenal; ACC; acetyl-coA carboxylase; ALT; alanine aminotransferase; AMPK; adenosine monophosphate-activated protein kinase; ANOVA; analysis of variance; AST; aspartate transaminase; ATGL; adipose triglycerid
Keywords: سمیت لیپتو; ACSL1; long-chain acyl-CoA synthetase 1; ATGL; adipose triglyceride lipase; CerS5; ceramide synthase 5; CPT; carnitine palmitoyltransferase; DAG; diacylglycerol; DGAT; diacylglycerol acyltransferase; ER; endoplasmic reticulum; ERK; extracellular signal re
Keywords: سمیت لیپتو; Facilitated transport; Leptin; Lipotoxicity; Spexin; Weight regain;
Keywords: سمیت لیپتو; Atherosclerosis; Macrophages; Lipotoxicity; Prednisolone; Liposomal nanoparticles; CVD; cardiovascular disease; DPPC; dipalmitoylphosphatidylcholine; DSPE; distearoylphosphatidylethanola-mine; GC; glucocorticoids; LDLr â/â; low-density lipoprotein re
Keywords: سمیت لیپتو; Diabetic cardiomyopathy; Lipotoxicity; Fatty acid oxidation;
Keywords: سمیت لیپتو; LC-SFAs, long-chain saturated fatty acids; MC-SFAs, medium-chain saturated fatty acids; ROS, reactive oxygen species; SFAs, saturated fatty acids; TG, triacylglycerolFatty acid; Lipotoxicity; Laurate; Oleate
Keywords: سمیت لیپتو; Articular cartilage; Polysebacic anhydride; Microparticles; Delivery; Lipotoxicity; Hydrogel;
Keywords: سمیت لیپتو; Diabetic nephropathy; Autophagy; Lipotoxicity; Epithelial-to-mesenchymal transition; Rapamycin;
Keywords: سمیت لیپتو; Apoptosis; Endoplasmic reticulum (ER) stress; Lipotoxicity; INS-1 beta cell; Iron; PalmitateATF6, activating transcription factor-6; CHOP, C/EBP homologous protein; DFO, deferoxamine; DS, deferasirox; ER, endoplasmic reticulum; FFA, free fatty acid; FTH,
Keywords: سمیت لیپتو; adiponectin; cytokines; gut microbiota; lipotoxicity; PNPLA3AGE, Advanced glycation end products; ALT, Alanine aminotransferase; AMPK, AMP-activated protein Kinase; APPL1 and 2, Adaptor protein 1 and 2; ATP, Adenosine tri-phosphatase; BMI, Basal Metabolic
Keywords: سمیت لیپتو; NAFLD; NASH; Lipotoxicity; Free cholesterol; Cholesterol homeostasis; Liver;
Keywords: سمیت لیپتو; Pancreatitis; Obesity; Fibrosis; Lipotoxicity; Outcomes; Multi system organ failure;
Keywords: سمیت لیپتو; BALB; Balb/cJ; Bl6; C57BL/6N; DAG; diacylglycerol; FFA; free fatty acids; FAO; fatty acid oxidation; BCAA; branched-chain amino acids; WAT; white adipose tissue; BAT; brown adipose tissue; ACN; acetonitrile; PPAR-α; peroxisome proliferator-activated rece
Keywords: سمیت لیپتو; Diet-induced obesity; Cardiomyopathy; Cardiac energetics; Lipotoxicity; Calcium homeostasis;
Keywords: سمیت لیپتو; ACAT; acyl-CoA cholesterol acyltransferase; ACC; acetyl CoA carboxylases; ACLY; ATP citrate lyases; ACSL; acyl CoA synthetases long chain family; ADRP; adipose differentiation related protein; AGP; advanced glycation end products; AGPAT; acylglycerophosph
Keywords: سمیت لیپتو; Mitochondrion; Steatosis; Non-alcoholic steatohepatitis (NASH); Lipotoxicity;
Keywords: سمیت لیپتو; Toll-like receptor 4; Unsaturated fatty acids; Saturated fatty acids; Polyunsaturated fatty acids; Inflammation; Lipotoxicity; Endothelial cells; Lipid peroxide;
Keywords: سمیت لیپتو; Nonalcoholic Fatty Liver Disease; Lipotoxicity; Wound-Healing Response; MisrepairNAFL, nonalcoholic fatty liver; NAFLD, nonalcoholic fatty liver disease; NASH, nonalcoholic steatohepatitis; SHH, sonic hedgehog; SMO, smoothened, frizzled class receptor; TN
A critical role for very long-chain fatty acid elongases in oleic acid-mediated Saccharomyces cerevisiae cytotoxicity
Keywords: سمیت لیپتو; FA; fatty acid; CAT; catalase; GPX; glutathione peroxidase; GSH; glutathione; MDA; methane dicarboxylic aldehyde; NAC; N-acetyl cysteine; OLA; oleic acid; PUFA; polyunsaturated fatty acid; ROS; reactive oxygen species; SOD; superoxide dismutase; TBARS; th
Palmitate induces lipoapoptosis in Schwann cells through ROS generation-mediated STAMP2 downregulation
Keywords: سمیت لیپتو; Schwann cells; Lipotoxicity; Palmitate; ROS; STAMP2;
Sall2 knockdown exacerbates palmitic acid induced dysfunction and apoptosis of pancreatic NIT-1 beta cells
Keywords: سمیت لیپتو; PA; palmitic acid; NEFA; non-esterified fatty acid; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; shRNA; short hairpin RNA; CCK8; cell counting assay kit-8; Pdx-1; pancreatic and duodenal homeobox factor 1; MafA; V-maf musculoaponeuro
(p-ClPhSe)2 stabilizes metabolic function in a rat model of neuroendocrine obesity induced by monosodium glutamate
Keywords: سمیت لیپتو; Obesity; Organoselenium; Hypothalamic regulation; Metabolic disorder; Lipotoxicity; Monosodium glutamate;
Inhibition of central de novo ceramide synthesis restores insulin signaling in hypothalamus and enhances β-cell function of obese Zucker rats
Keywords: سمیت لیپتو; Ceramide; Lipotoxicity; Hypotalamus; Insulin resistance; Insulin secretion; IR; insulin resistance; HFD; high fat diet; T2D; Type 2 diabetes mellitus; PKCs; proteins kinase C; ER; endoplasmic reticulum; CerS; ceramide Synthase; Thr-308; Threonine 308; Ser
MicroRNAs in the pathogenesis and treatment of progressive liver injury in NAFLD and liver fibrosis
Keywords: سمیت لیپتو; ApoB; apolipoprotein B; CBDL; common bile duct ligation; CCl4; carbon tetrachloride; CPT1; peroxisome carnitine palmitoyl transferase 1; CREBH; cAMP responsive element binding protein H; DNL; de novo lipogenesis; ECM; extracellular matrix; ER; endoplasmic
Adiponectin receptor agonist AdipoRon decreased ceramide, and lipotoxicity, and ameliorated diabetic nephropathy
Keywords: سمیت لیپتو; 8-epi-PGF2α; 8-epi-prostaglandin F2α; 8-OH-dG; 8-hydroxy-2-deoxyguanosine; ACC; Acetyl-CoA carboxylase; AdipoR1 and AdipoR2; Adiponectin receptors 1 and 2; AMPK; AMP-dependent kinase; CKD; Chronic kidney disease; COL IV; Type IV collagen; eNOS; Endothel
Arctigenin protects against steatosis in WRL68 hepatocytes through activation of phosphoinositide 3-kinase/protein kinase B and AMP-activated protein kinase pathways
Keywords: سمیت لیپتو; Arctigenin; Lipotoxicity; Steatosis; Inflammation; Nonalcoholic fatty liver disease; ACC1; acetylcoenzyme A carboxylase 1; ACO; acyl-CoA oxidase; ATG; arctigenin; CPT-1; carnitine palmitoyltransferase 1; FAS; fatty acid synthase; MDA; malondialdehyde; NAF
Hsp72 protects against liver injury via attenuation of hepatocellular death, oxidative stress, and JNK signaling
Keywords: سمیت لیپتو; Lipotoxicity; Drug-induced injury; JNK; MCD; DDC;
Palmitate lipotoxicity in enteric glial cells: Lipid remodeling and mitochondrial ROS are responsible for cyt c release outside mitochondria
Keywords: سمیت لیپتو; Palmitate; Lipotoxicity; Cardiolipin; Mitochondrial ROS; Cytochrome c; Enteric glial cells;
Egr-1 transactivates WNT5A gene expression to inhibit glucose-induced β-cell proliferation
Keywords: سمیت لیپتو; β-cell; Wnt5a; Egr-1; Glucolipotoxicity; Lipotoxicity; Saturated fatty acids;
Lipid droplets induced by secreted phospholipase A2 and unsaturated fatty acids protect breast cancer cells from nutrient and lipotoxic stress
Keywords: سمیت لیپتو; AA; arachidonic acid; AMPK; AMP-dependent protein kinase; ATGL; adipose triglyceride lipase; cPLA2α; cytosolic group IVA PLA2; CPT1; carnitine O-palmitoyltransferase 1; CPT1A; the liver isoform of CPT1; DGAT1; diacylglycerol acyltransferase 1; DHA; docos
Oleic acid protects saturated fatty acid mediated lipotoxicity in hepatocytes and rat of non-alcoholic steatohepatitis
Keywords: سمیت لیپتو; Oleic acid; Palmitic acid; Olive oil; Lipotoxicity; Non-alcoholic steatohepatitis;