Keywords: گیرنده لیپوپروتئین چگالی کم; NAFLD; nonalcoholic fatty liver disease; NASH; nonalcoholic steatohepatitis; FC; free cholesterol; VLDL; very low density lipoprotein; LDL; low density lipoprotein; mTOR; mechanistic target of rapamycin signaling; AMPK; AMP-activated protein kinase; TG; t
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Keywords: گیرنده لیپوپروتئین چگالی کم; Familial hypercholesterolemia; Low density lipoprotein receptor; High resolution melt analysis; Cardiovascular disease; Cholesterol;
Keywords: گیرنده لیپوپروتئین چگالی کم; HMG-CoA R; 3-hydroxy-3-methylglutaryl-coenzyme A reductase; 3α-diol; 5alpha-androstane-3alpha,17beta-diol; 3β-diol; 5alpha-androstane-3beta,17beta-diol; 7α-OH; 7α-hydroxycholesterol; 7β-OH; 7β-hydroxycholesterol; 7-keto; 7-ketocholesterol; 24(S)-OH;
Keywords: گیرنده لیپوپروتئین چگالی کم; Familial hypercholesterolemia; Low density lipoprotein receptor; Lipid-lowering drugs; Guidelines;
Keywords: گیرنده لیپوپروتئین چگالی کم; 27-HC; 27-hydroxycholesterol; ER; estrogen receptor; CYP27A1; cytochrome P450, family 27, subfamily A, polypeptide 1; LXR; liver X receptor; BRCA1 and BRCA2; Breast cancer 1 and 2; LDL; low density lipoprotein; HDL; high density lipoprotein; ApoE; apolipo
Keywords: گیرنده لیپوپروتئین چگالی کم; ACSVL3; acyl-coA synthetase VL3; ALDH1; aldehyde dehydrogenase; ALDOA; aldolase A; ALDOC; aldolase C; AMPK; 5â² AMP-activated protein kinase; ASNS; asparagine synthetase; BTICs; brain tumor initiating cells; 3-BrOP; 3-bromo-2-oxopropionate-1-propyl ester
Keywords: گیرنده لیپوپروتئین چگالی کم; ACC; acetyl CoA carboxylase; ACYL; ATP citrate lyase; Akt2; rac-β-serine-threonine kinase; ALA; α-linolenic acid; ALT; alanine aminotransferase; ARA; arachidonic acid, 20:4,Ï6; AST; aspartate aminotransferase; ATGL; adipocyte triglyceride lipase; CD36;
Keywords: گیرنده لیپوپروتئین چگالی کم; Familial hypercholesterolemia; Mutations; Cascade screening; Index patient; Low density lipoprotein receptor; Apolipoprotein B;
Keywords: گیرنده لیپوپروتئین چگالی کم; APEX; arrayed primer extension; apoB-100; apolipoprotein B-100; apoE; apolipoprotein E; CETP; cholesteryl ester transfer protein; CVDs; cardiovascular diseases; DGGE; denaturing gradient gel electrophoresis; DHPLC; denaturing high performance liquid chrom
Keywords: گیرنده لیپوپروتئین چگالی کم; AMI; acute myocardial infarction; EMT; epithelial-to-mesenchymal transition; APOA1; apolipoprotein A1; LDLR; low density lipoprotein receptor; FGFR1; fibroblast growth factor 1; ACTA2; smooth muscle alpha-actin; EGF; epidermal growth factor; IL1B; IL-1 be
Keywords: گیرنده لیپوپروتئین چگالی کم; Serum lipids; Plasma lipids; Cancer; Lipoproteins; TGs; triglycerides; TG; triglyceride; FFAs; free fatty acids; VLDL; very low density lipoprotein; LDL; low density lipoprotein; HDL; high density lipoprotein; LPL; lipoprotein lipase; LDL-R; low density l
Keywords: گیرنده لیپوپروتئین چگالی کم; CYP7A1; cytochrome P450 family 7 subfamily A polypeptide 1; FXRα; farnesoid X receptor α; HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase; LDLR; low density lipoprotein receptor; PCSK9; proprotein convertase subtilisin/kexin type 9; SREBP2; sterol regul
Keywords: گیرنده لیپوپروتئین چگالی کم; Familial hypercholesterolemia; Arterial calcification; Low density lipoprotein receptor; Animal models; Osteoblasts; Atherosclerosis;
Keywords: گیرنده لیپوپروتئین چگالی کم; Kupffer cell; Lipoprotein metabolism; Liver; Low density lipoprotein receptor; Low density lipoprotein receptor-related protein; Megalin;
Keywords: گیرنده لیپوپروتئین چگالی کم; ABC; ATP binding cassette transporter; AMPK; AMP kinase; AP; activator protein; Akt; protein kinase B; Apo; apolipoprotein; apoB48R; apolipoprotein B48 receptor; CD; cluster of differentiation; CM; chylomicrons; CMR; chylomicron remnants; COX; cyclooxygen
Keywords: گیرنده لیپوپروتئین چگالی کم; AD; Alzheimer's disease; Aβ; β amyloid peptide; ERT; estrogen replacement therapy; ESR; estrogen receptor; E1; estrone; E2; estradiol; E3; estriol; CYP; cytochrome P450; CYP11A1; cytochrome P450 cholesterol side chain cleavage enzyme; HSD-3β; 3β-hydro
Keywords: گیرنده لیپوپروتئین چگالی کم; CAD; Coronary artery disease; CHD; Coronary heart disease; CVD; Cardiovascular disease; GP; Genetic profiles; HWE; Hardy-Weinberg equilibrium; INE; National Institute of Statistics; LD; Linkage disequilibrium; LDLR; Low density lipoprotein receptor; MAF;
Ordered opening of LDL receptor binding domain of human apolipoprotein E3 revealed by hydrogen/deuterium exchange mass spectrometry and fluorescence spectroscopy
Keywords: گیرنده لیپوپروتئین چگالی کم; Apolipoprotein E3; Helix bundle opening; LDL receptor; Hydrogen deuterium exchange mass spectrometry; Fluorescence spectroscopy; Lipoprotein binding; apoE3; apolipoprotein E3; CD; circular dichroism; CT; C-terminal; GdnHCl; guanidine hydrochloride; FI; fl
Jatrophane diterpenoids from Euphorbia helioscopia and their lipid-lowering activities
Keywords: گیرنده لیپوپروتئین چگالی کم; Euphorbia helioscopia; Jatrophanes; Hyperlipidemia; Lipid-lowering; LDL receptor; CVD; cardiovascular disease; CHD; coronary heart disease; LDL; low density lipoprotein; LDL-C; low density lipoprotein cholesterol; LDLR; low density lipoprotein receptor; H
LDL Receptor Gene-ablated Hamsters: A Rodent Model of Familial Hypercholesterolemia With Dominant Inheritance and Diet-induced Coronary Atherosclerosis
Keywords: گیرنده لیپوپروتئین چگالی کم; LDL receptor; Golden Syrian hamster; Hyperlipidemia; Atherosclerosis; CRISPR/Cas9; ApoB; apolipoprotein B; ApoE; Apolipoprotein E; CETP; cholesteryl ester transfer protein; CAD; coronary artery disease; CD; chow diet; CHD; cardiovascular heart diseases; C
Ganoderic Acid A improves high fat diet-induced obesity, lipid accumulation and insulin sensitivity through regulating SREBP pathway
Keywords: گیرنده لیپوپروتئین چگالی کم; Ganoderic Acid A; SREBPs; Obesity; Insulin resistance; Lipid accumulation; ABCA1; ATP-binding cassette transporter 1; ACC; acetyl-CoA carboxylase; ACO; acyl-CoA oxidase; BAT; brown adipose tissue; CPT1; carntine palmitoyltransferase 1; CYP7A1; cholesterol
Part A: Temporal and dose-dependent transcriptional responses in the liver of fathead minnows following short term exposure to the polycyclic aromatic hydrocarbon phenanthrene
Keywords: گیرنده لیپوپروتئین چگالی کم; SREBF1; sterol regulatory element binding transcription factor 1; FASN; fatty acid synthase; HSD17B12; hydroxysteroid (17-beta) dehydrogenase 12; ACACA; acetyl-CoA carboxylase alpha; CYB5A; cytochrome b5 type A (microsomal); SLC27A4; solute carrier family
Part B: Morphometric and transcriptomic responses to sub-chronic exposure to the polycyclic aromatic hydrocarbon phenanthrene in the fathead minnow (Pimephales promelas)
Keywords: گیرنده لیپوپروتئین چگالی کم; PNPLA2; patatin-like phospholipase domain containing 2; APOE; apolipoprotein E; NPC1; Niemann-Pick disease, type C1; LCAT; lecithin-cholesterol acyltransferase; DGAT1; diacylglycerol O-acyltransferase 1; LRP1; low density lipoprotein-related protein 1 (al
Ablating both Fabp1 and Scp2/Scpx (TKO) induces hepatic phospholipid and cholesterol accumulation in high fat-fed mice
Keywords: گیرنده لیپوپروتئین چگالی کم; 3αHSD; 3alpha-hydroxysteroid reductase; ABCA1; ATP-binding cassette sub-family A member 1; ABCG1; 4, 5 or 8, ATP-binding cassette sub-family G member 1,4, 5 or 8; ACAT2; acetyl-CoA acetyltransferase (Soat2 gene); ACC1; acetyl-CoA carboxylase (Acaca gene)
Deletion of JNK2 prevents vitamin-D-deficiency-induced hypertension and atherosclerosis in mice
Keywords: گیرنده لیپوپروتئین چگالی کم; 1,25(OH)2D; 1,25-dihydroxy vitamin D; 25(OH)D; 25-hydroxy vitamin D; CVD; cardiovascular disease; CD36; cluster of differentiation 36; CHOP; CEBP homologous protein; eNOS; endothelial nitric oxide synthase; ER; endoplasmic reticulum; HTN; hypertension; IC
The challenges and promise of targeting the Liver X Receptors for treatment of inflammatory disease
Keywords: گیرنده لیپوپروتئین چگالی کم; ABC; ATP-Binding Cassette; DR4; direct repeat 4; ER; endoplasmic reticulum; HDL; high density lipoprotein; LDLR; low density lipoprotein receptor; LXR; Liver X Receptor; LXRE; LXR response element; NCoR; nuclear co-repressor; NPC1L1; Niemann-Pick C1-like
Activation of Nrf2 signaling by natural products-can it alleviate diabetes?
Keywords: گیرنده لیپوپروتئین چگالی کم; Nrf2; type 2 diabetes; natural products; hyperglycemia; cellular stress; insulin sensitivity; β-cell function; vascular complications; AGE; advanced glycation end products; AhR; arylhydrocarbon receptor; AMPK; AMP-activated kinase; ARE; antioxidant respo
Apolipoprotein mediates soft-shelled turtle systemic septicemia spherical virus (STSSSV) infection
Keywords: گیرنده لیپوپروتئین چگالی کم; STSSSV; soft-shelled turtle systemic septicemia spherical virus; PApoB; Pelodiscus sinensis apolipoprotein B; ApoB; apolipoprotein B; STSS; soft-shelled turtle systemic septicemia; Ab; antibody; VOPBA; viral overlay protein binding assay; PBS; phosphate b
Prenatal betaine exposure alleviates corticosterone-induced inhibition of CYP27A1 expression in the liver of juvenile chickens associated with its promoter DNA methylation
Keywords: گیرنده لیپوپروتئین چگالی کم; SREBP; sterol regulator element-binding protein; HMGCR; 3-hydroxy-3-methylglutaryl coenzyme A reductase; CYP7A1; cholesterol-7alpha-hydroxylase; CYP27A1; cholesterol-27alpha-hydroxylase; ACAT1; acetyl-CoA cholesterol acyltransferase 1; LDLR; low density l
The efficacy advantage of evolocumab (AMG 145) dosed at 140Â mg every 2Â weeks versus 420Â mg every 4Â weeks in patients with hypercholesterolemia: Evidence from a meta-analysis
Keywords: گیرنده لیپوپروتئین چگالی کم; ApoB/ApoA-I; Apolipoprotein B/Apolipoprotein A-I; ALT; Alanine aminotransferase; AST; Aspartate aminotransferase; CI; Confidence interval; CVD; Cardiovascular disease; CHD; Coronary heart disease; AMG 145; Evolocumab; Q2W; Every 2Â weeks; Q4W; Every 4Â we
Improvement of the omega 3 index of healthy subjects does not alter the effects of dietary saturated fats or n-6PUFA on LDL profiles
Keywords: گیرنده لیپوپروتئین چگالی کم; Lipids; Omega-3 polyunsaturated fatty acids; Saturated fatty acids; Nuclear magnetic resonance spectroscopy; Lipoprotein profiles; 18:2n-6; linoleic acid; 22:6n-3; docosahexaenoic acid; 20:5n-3; eicosapentaenoic acid; BMI; body mass index; CVD; cardiovasc
Hypercholesterolemia Causes Circadian Dysfunction: A Potential Risk Factor for Cardiovascular Disease
Keywords: گیرنده لیپوپروتئین چگالی کم; Hypercholesterolemia; Circadian rhythms; Clock gene; Low density lipoprotein receptor;
Purinergic P2Y receptors: Molecular diversity and implications for treatment of cardiovascular diseases
Keywords: گیرنده لیپوپروتئین چگالی کم; ADP; adenosine 5â²-diphosphate; AgRP; agouti-related peptide; AMPK; 5â²-AMP-activated protein kinase; ApnA; diadenosine polyphosphate; ApoE; apolipoprotein E; AT1R; angiotensin II type 1 receptor; ATP; adenosine 5â²-triphosphate; BN-PAGE; blue native-p
Air particulate matter induced oxidative stress and inflammation in cardiovascular disease and atherosclerosis: The role of Nrf2 and AhR-mediated pathways
Keywords: گیرنده لیپوپروتئین چگالی کم; HDL; high density lipoprotein; apoE; apolipoprotein E; UFP; ultrafine particles; CD40; cluster of differentiation 40; HUVEC; human umbilical vein endothelial cells; HMEC; human microvascular endothelial cells; BAEC; bovine aortic endothelial cells; mRNA;
Metabolic roles of poly(ADP-ribose) polymerases
Keywords: گیرنده لیپوپروتئین چگالی کم; ABCA1; ATP-binding cassette sub-family A member 1; ACACA; acetyl-CoA carboxylase alpha; ACBD3; acyl-CoA binding domain containing 3; ACLY; ATP citrate lyase; ADP; adenosine diphosphate; ADPR; ADP-ribose; AFLD; alcoholic fatty liver disease; AIF; apoptosis
New insights into cellular cholesterol acquisition: promoter analysis of human HMGCR and SQLE, two key control enzymes in cholesterol synthesis
Keywords: گیرنده لیپوپروتئین چگالی کم; ChIP-seq; chromatin immunoprecipitation-sequencing; DHCR7; 7-dehydrocholesterol reductase; DHCR24; 24-dehydrocholesterol reductase; EMSA; electrophoretic mobility shift assay; FCLPDS; fetal calf lipoprotein-deficient serum; FCS; fetal calf serum; HMGCR; 3
Culturing of HepG2 cells with human serum improve their functionality and suitability in studies of lipid metabolism
Keywords: گیرنده لیپوپروتئین چگالی کم; CYP; cytochrome P450; LDLR; low density lipoprotein receptor; MTP; microsomal triglyceride transfer protein; PCSK9; proprotein subtilisin/kexin type 9; HepG2; Human serum; FBS; Lipoproteins; Bile acids;
Crabapple fruit extracts lower hypercholesterolaemia in high-fat diet-induced obese mice
Keywords: گیرنده لیپوپروتئین چگالی کم; Crabapple; Hyperlipidaemia; Hypercholesterolaemia; Metabolic syndrome; Anti-oxidation; CYP7A1; Procyanidin (PubChem CID: 107876); Epicatechin (PubChem CID: 72276); Isoastilbin (PubChem CID: 10114809); Quercetin 3-O-glucoside (PubChem CID: 44258003); Avicu
miRNA and cholesterol homeostasis
Keywords: گیرنده لیپوپروتئین چگالی کم; miRNA; microRNA; SREBP; sterol regulatory element-binding protein; SCAP; SREBP cleavage-activating protein; Ago; Argonaute family protein; RISC; RNA-induced-silencing-complex; Fbxw7; F-box and WD repeat domain containing 7; NAFLD; non-alcoholic fatty live
Streptococcal serum opacity factor promotes cholesterol ester metabolism and bile acid secretion in vitro and in vivo
Keywords: گیرنده لیپوپروتئین چگالی کم; Bmax; maximum uptake; C; cholesterol; CE; cholesteryl ester; CERM; cholesteryl ester rich microemulsion; FBS; fetal bovine serum; FC; free cholesterol; GC-MS; gas chromatography-mass spectrometry; HDL; high density lipoprotein; HPTLC; high performance
Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes
Keywords: گیرنده لیپوپروتئین چگالی کم; ABC; ATP-binding cassette transporter; AGPAT2; 1-acylglycerol-3-phosphate O-acyltransferase; AhR; arylhydrocarbon receptor; AKR1C1; aldo-keto reductase 1C1; APO; apolipoprotein; ASBT; apical sodium dependent bile acid transporter; BAs; bile acids; BSEP; b
Cyp3a deficiency enhances androgen receptor activity and cholesterol synthesis in the mouse prostate
Keywords: گیرنده لیپوپروتئین چگالی کم; AR; androgen receptor; ARE; androgen response element; ChIP; chromatin immunoprecipitation; CYP3A; cytochrome P450 3A; Ddt; D-dopachrome tautomerase; Hmgcr; HMG-CoA reductase; Hmgcs1; HMG-CoA synthase 1; HPLC; high-performance liquid chromatography; Ldlr;
Research ArticleHematopoietic overexpression of Cyp27a1 reduces hepatic inflammation independently of 27-hydroxycholesterol levels in Ldlrâ/â mice
Keywords: گیرنده لیپوپروتئین چگالی کم; NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; KC; Kupffer cell; 27HC; 27-hydroxycholesterol; Ldl; low density lipoprotein receptor; HFC; high-fat high-cholesterol; Wt; wild type; tp; transplanted; TG; triglycerides; FFA; f
How do eggs get fat? Insights into ovarian fatty acid accumulation in the shortfinned eel, Anguilla australis
Keywords: گیرنده لیپوپروتئین چگالی کم; 11-KT; 11-ketotestosterone; apoB; apolipoprotein B; BSA; bovine serum albumin; LPL; lipoprotein lipase; LDL; low density lipoprotein; LDLr; low density lipoprotein receptor; PBS; phosphate-buffered saline; PFA; paraformaldehyde; VLDL; very-low density lip
The closed conformation of the LDL receptor is destabilized by the low Ca++ concentration but favored by the high Mg++ concentration in the endosome
Keywords: گیرنده لیپوپروتئین چگالی کم; Low density lipoprotein receptor; Surface plasmon resonance; Binding; Endosome;
MMP-2 inhibits PCSK9-induced degradation of the LDL receptor in Hepa1-c1c7 cells
Keywords: گیرنده لیپوپروتئین چگالی کم; Matrix metalloproteinase-2; Sterol-regulatory element binding protein; Low density lipoprotein receptor; Pro-protein convertase subtilisin/kexin type 9; Cholesterol; Atherosclerosis;
Behavioral stress reduces RIP140 expression in astrocyte and increases brain lipid accumulation
Keywords: گیرنده لیپوپروتئین چگالی کم; ABCA; ATP-binding cassette transporter; ABCG1; ATP-binding cassette sub-family G; ApoE; Apolipoprotein E; CYP46; cholesterol 24S-hydroxylase; CYP51; Sterol 14 alpha-demethylase; ER; endoplasmic reticulum; FSS; forced swim stress; H2O2; Hydrogen peroxide;
Molecular characterization and RNA interference analysis of vitellogenin receptor from Nilaparvata lugens (Stål)
Keywords: گیرنده لیپوپروتئین چگالی کم; Nilaparvata lugens; Low density lipoprotein receptor; Vitellogenin receptor; Reproduction; RNAi; Juvenile hormone
Activation of mTORC1 disrupted LDL receptor pathway: A potential new mechanism for the progression of non-alcoholic fatty liver disease
Keywords: گیرنده لیپوپروتئین چگالی کم; Inflammation; Mammalian target of rapamycin complex 1; Low density lipoprotein receptor; Non-alcoholic fatty liver disease; Cholesterol homeostasis
High fructose consumption induces DNA methylation at PPARα and CPT1A promoter regions in the rat liver
Keywords: گیرنده لیپوپروتئین چگالی کم; Epigenetics; Metabolic syndrome; Nutrition; Corn syrup; Gene expression; Dyslipidemia; PPARα; peroxisome proliferator-activated receptor α; CPT1&Agr; carnitine palmitoyltransferase 1A; LDLR; low density lipoprotein receptor; MTTP; microsomal triglycerid