Keywords: microRNA; Endothelial microparticle; microRNA-126; LRP6; Vascular smooth muscle cell; Human; Mouse; Human coronary artery endothelial cell; Vascular remodeling, diabetes, hyperglycaemic condition; Cell culture; Neointima formation;
مقالات ISI (ترجمه نشده)
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Keywords: AAV4; adeno-associated virus serotype 4; BDNF; brain-derived neurotrophic factor; bFGF; fibroblast growth factor 2; BME; β-mercaptoethanol; BMP; bone morphogenetic protein; Cas9; CRISPR associated protein 9; Cla; claustrum; CN; caudate nucleus; CRISPR; c
Keywords: Alternative splicing; Alzheimer's disease; LRP6; Wnt/β-catenin signaling;
MiR-183 promotes preadipocyte differentiation by suppressing Smad4 in goats
Keywords: PPARγ; peroxisome proliferator-activated receptor γ; C/EBPα; CCAAT/enhancer binding protein α; FAS; fatty acid synthase; TGFβ; transforming growth factor β; LRP6; low density lipoprotein receptor related protein 6; SREBP-1c; sterol regulatory elemen
Lipid rafts disruption induces apoptosis by attenuating expression of LRP6 and survivin in triple negative breast cancer
Keywords: Lipid rafts; Methyl β cyclodextrin; LRP6; Triple negative breast cancer;
Lrp6 is a target of the PTH-activated αNAC transcriptional coregulator
Keywords: αNAC; α chain of nascent polypeptide associated complex; PTH; Parathyroid Hormone; PKA; protein kinase A; ChIP; chromatin immunoprecipitation; ChIP-Seq; ChIP-sequencing; LRP6; Low density lipoprotein receptor-Related Protein 6; iPTH; intermittent PTH; P
Garlic-derived compound S-allylmercaptocysteine inhibits hepatocarcinogenesis through targeting LRP6/Wnt pathway
Keywords: Axin1; axis inhibition protein 1; DKK-1; Dickkopf Wnt signaling pathway inhibitor 1; DVL2; disheveled 2; FADD; Fas-associated protein with death domain; HCC; hepatocellular carcinoma; KD; knock-down; LDH; lactate dehydrogenase; LRP6; low-density lipoprote
MiR-183 inhibits osteosarcoma cell growth and invasion by regulating LRP6-Wnt/β-catenin signaling pathway
Keywords: miR-183; Osteosarcoma; LRP6; Wnt/β-catenin;
Original ArticleSRI36160 is a specific inhibitor of Wnt/β-catenin signaling in human pancreatic and colorectal cancer cells
Keywords: Wnt signaling; Benzimidazole; Niclosamide; Targeted therapy; Drug discovery; APC; adenomatous polyposis coli; CIC; cancer initiating cell; Fzd; frizzled; LRP6; low-density lipoprotein receptor-related protein-6; PDAC; pancreatic ductal adenocarcinoma; PI;
Effects of Klotho on fibrosis and cancer: A renal focus on mechanisms and therapeutic strategies
Keywords: ACE; angiotensin converting enzyme; ADAM; a disintegrin and metalloproteinase; AKI; acute kidney injury; ANGII; angiotensin II; AT1; angiotensin II receptor type 1; AMPKα; AMP-activated protein kinase α; α-SMA; α-smooth muscle actin; CKD; chronic kidn
Down-regulation of Wt1 activates Wnt/β-catenin signaling through modulating endocytic route of LRP6 in podocyte dysfunction in vitro
Keywords: CKD; Chronic kidney disease; LRP; Low density lipoprotein receptor-related protein; Axin; Axis inhibition protein; APC; Adenomatosis polyposis coli; GSK-3β; Glycogen synthase kinase-3β; TCF/LEF; T-cell factor/lymphocyte enhancer factor; Wt1; Wilms' tumo
Blocking of the interaction between Wnt proteins and their co-receptors contributes to the anti-tumor effects of adenovirus-mediated DKK3 in glioblastoma
Keywords: DKK3; Wnt3a; Wnt5a; LRP6; Glioblastoma;
MicroRNA-27a decreases the level and efficiency of the LDL receptor and contributes to the dysregulation of cholesterol homeostasis
Keywords: miR-27a; LDLR; PCSK9; LRP6; LDLRAP1; Cholesterol homeostasis; Atherosclerosis; LDL; low-density lipoprotein; LDL-C; LDL cholesterol; LDLR; LDL receptor; PCSK9; proprotein convertase subtilisin/kexin type 9; LRP6; LDLR-related protein 6; LDLRAP1; LDLR-adap
Pigment Epithelium-Derived Factor (PEDF) Inhibits Wnt/β-catenin Signaling in the Liver
Keywords: Extracellular Matrix; PEDF; Wnt/β-Catenin; BABB; benzyl alcohol/benzyl benzoate; CM; conditioned medium; ECM; extracellular matrix; ERK; extracellular signal-regulated kinase; FDR; false-discovery rate; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GO
Rottlerin induces Wnt co-receptor LRP6 degradation and suppresses both Wnt/β-catenin and mTORC1 signaling in prostate and breast cancer cells
Keywords: 4E-BP1; eukaryotic initiation factor 4E binding protein 1; AMPK; 5â²-AMP-activated protein kinase; APC; adenomatous polyposis coli; CK1; casein kinase 1; CM; conditioned medium; eIF4E; eukaryotic initiation factor 4E; GSK3β; glycogen synthase kinase-3β
Inhibition of Wnt/β-catenin pathway by niclosamide: A therapeutic target for ovarian cancer
Keywords: Ovarian cancer; Cancer stem cells; LRP6; Wnt/β-catenin; Niclosamide; Chemoresistance
Syndecan-4 inhibits Wnt/β-catenin signaling through regulation of low-density-lipoprotein receptor-related protein (LRP6) and R-spondin 3
Keywords: Wnt; Syndecan-4; LRP6; Fibronectin; R-spondin;
Role of the Rap2/TNIK kinase pathway in regulation of LRP6 stability for Wnt signaling
Keywords: Rap2 GTPase; LRP6; TNIK; Wnt signaling; Xenopus;
Cripto-1 enhances the canonical Wnt/β-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors
Keywords: TDGF-1; teratocarcinoma-derived growth factor-1; CFC; Cripto-1/FRL1/Cryptic; GPI; glycosylphosphatidylinositol; TGF-β; transforming growth factor-β; GDF; growth differentiation factor; Tcf; T-cell factor; Fz; frizzled; LRP; low-density lipoprotein recep
CTGF/CCN2 activates canonical Wnt signalling in mesangial cells through LRP6: Implications for the pathogenesis of diabetic nephropathy
Keywords: Connective tissue growth factor; Wnt; Glycogen synthase kinase 3β; β-Catenin; LRP6; Diabetic nephropathy
Lrp5 and Lrp6 redundantly control skeletal development in the mouse embryo
Keywords: Wnt; Lrp5; Lrp6; β-catenin; α-catenin; Osteoblast; Mouse; Chondrocyte;
Urban planning of the endoplasmic reticulum (ER): How diverse mechanisms segregate the many functions of the ER
Keywords: ACS4/FACL4; acyl-CoA synthase 4; ACAT/SOAT; acyl-CoA cholesteryl acyl transferase; AMFR; autocrine motility factor receptor; BAP31; B-cell receptor-associated protein of 31Â kDa; BiP; immunoglobulin binding protein; CHOP; CCAAT/enhancer binding protein (C
The expression and distribution of Wnt and Wnt receptor mRNAs during early sea urchin development
Keywords: Axis specification; Polarity; Early patterning; Wnt signaling; Wnt; Frizzled; LRP6; β-Catenin; Dishevelled; Maternal mRNA; Sea urchin; Protein degradation; Micromeres
Detection of endogenous LRP6 expressed on human cells by monoclonal antibodies specific for the native conformation
Keywords: Wnt; LRP6; Monoclonal antibody
The role of the Ser/Thr cluster in the phosphorylation of PPPSP motifs in Wnt coreceptors
Keywords: Wnt signaling pathway; LRP6; GSK3β; CK1; Biochemical role; Phosphorylation; β-Catenin
Thiazolidinediones Downregulate Wnt/β-Catenin Signaling Via Multiple Mechanisms in Breast Cancer Cells
Keywords: PPARγ; thiazolidinedione; troglitazone; breast cancer; Wnt; β-catenin; TCF4; frizzled-1; LRP6; Akt
Receptors of anthrax toxin and cell entry
Keywords: Anthrax toxin; Receptors; Endocytosis; LRP6; ARAP3
Multiple PPPS/TP motifs act in a combinatorial fashion to transduce Wnt signaling through LRP6
Keywords: Wnt; LRP6; β-Catenin; Nuclear signaling; Cancer
Radiographic osteoarthritis at three joint sites and FRZB, LRP5, and LRP6 polymorphisms in two population-based cohorts
Keywords: Polymorphism; Osteoarthritis; Wnt; FRZB; LRP5; LRP6
Wnt/Lrp/β-catenin signaling suppresses adipogenesis by inhibiting mutual activation of PPARγ and C/EBPα
Keywords: Wnt/β-catenin signaling; Lrp6; PPARγ; C/EBPα; Adipogenesis
GRB10 binds to LRP6, the Wnt co-receptor and inhibits canonical Wnt signaling pathway
Keywords: GRB10; Wnt; LRP6; β-Catenin; Axin
Wise retained in the endoplasmic reticulum inhibits Wnt signaling by reducing cell surface LRP6
Keywords: Wnt; LRP6; Wise; Signaling; Endoplasmic reticulum; USAG-1; Ectodin;
Wnt-independent activation of β-catenin mediated by a Dkk1-Fz5 fusion protein
Keywords: Wnt signaling; Lrp5; Lrp6; Dkk1; Frizzled; Dishevelled; Wnt;
The duality of β-catenin function: A requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm
Keywords: Lens induction; Lens development; Morphogenesis; β-catenin; Pax6; Lrp6; Wnt signaling; Ectopic lentoid bodies;