Design, synthesis and biological evaluation of novel mansonone E derivatives prepared via CuAAC click chemistry as topoisomerase II inhibitors
Keywords: Mansonone E; Antitumour; Click chemistry; Topoisomerase; Cytotoxic activity; HPLC; High Performance Liquid Chromatography; HRMS; High Resolution Mass Spectrometer; MTT; methyl thiazolyl tetrazolium; NMR; nuclear magnetic resonance; Topo; topoisomerase; ME