Neuroprotective effects of hesperetin in mouse primary neurones are independent of CREB activation
Keywords: کیناز MAP; Flavonoid; Neurodegeneration; MAP kinase; Luciferase reporter
مقالات ISI کیناز MAP (ترجمه نشده)
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Biphenyl amide p38 kinase inhibitors 2: Optimisation and SAR
Keywords: کیناز MAP; p38 kinase; p38α; p38; CSBP; MAP kinase; Inhibitors; BPA, biphenyl amide; BPAs, biphenyl amides; Protein kinase X-ray structure; Binding mode; Structure-based drug design; Kinase selectivity
Stimulation by vasopressin of ERK phosphorylation and vector-driven water flux in astrocytes is transactivation-dependent
Keywords: کیناز MAP; EGF receptor; MAP kinase; Volume regulation; Water flux
The (pro)renin receptor: A new addition to the renin–angiotensin system?
Keywords: کیناز MAP; Prorenin; Renin; Receptor; Signalling; MAP kinase; Diabetes; Nephropathy; Angiotensin; Transgenic animal
Crystal structure of human mono-phosphorylated ERK1 at Tyr204
Keywords: کیناز MAP; MAP kinase; Extracellular signal-regulated protein kinase; ERK1; Crystal structure
Fluid shear stress inhibits TNF-mediated JNK activation via MEK5–BMK1 in endothelial cells
Keywords: کیناز MAP; Fluid shear stress; Endothelial cells; MAP kinase; TNF; Inflammation
The detergent resistance of Connexin43 is lost upon TPA or EGF treatment and is an early step in gap junction endocytosis
Keywords: کیناز MAP; Gap junction; Connexin43; Detergent resistance; Triton X-100; MAP kinase; EGF; TPA; Degradation; Phosphorylation;
The discovery of (R)-2-(sec-butylamino)-N-(2-methyl-5-(methylcarbamoyl)phenyl) thiazole-5-carboxamide (BMS-640994)—A potent and efficacious p38α MAP kinase inhibitor
Keywords: کیناز MAP; p38; MAP kinase; Aminothiazole; TNF
Angiotensin II induces proliferation of cultured rat astrocytes through c-Jun N-terminal kinase
Keywords: کیناز MAP; Src; PKC; Brainstem; JNK; MAP kinase; Angiotensin II; AT1 receptor;
Involvement of Rho-kinase in prostaglandin F2α-stimulated interleukin-6 synthesis via p38 mitogen-activated protein kinase in osteoblasts
Keywords: کیناز MAP; PGF2α; Rho-kinase; MAP kinase; IL-6; Osteoblast
Lysyl oxidase propeptide inhibits smooth muscle cell signaling and proliferation
Keywords: کیناز MAP; Lysyl oxidase; Lysyl oxidase propeptide; Cell proliferation; Matrix metalloproteinase-9; Map kinase; Cell signaling; Extracellular matrix; Vascular smooth muscle cells; Atherosclerosis; Restenosis; Western blots; Immunohistochemistry;
Syndecan-4 regulates platelet-derived growth factor-mediated MAP kinase activation by altering intracellular reactive oxygen species
Keywords: کیناز MAP; Reactive oxygen species; Syndecan-4; MAP kinase; Platelet-derived growth factor; DCF; fluorescent 2â²,7â²-dichlorofluorescein; ECM; extracellular matrix; FBS; fetal bovine serum; GST; glutathione-S-transferase; PDGF; platelet-derived growth factor; REF;
IL–1β-stimulated activation of ERK1/2 and p38α MAPK mediates the transcriptional up-regulation of IL–6, IL–8 and GRO-α in HeLa cells
Keywords: کیناز MAP; IL–1 receptor; Chemokine; MAP kinase; Inflammation; Epithelial cells
Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode
Keywords: کیناز MAP; p38 kinase; p38 alpha; p38; CSBP; MAP kinase; Inhibitors; Biphenyl amide; BPA; Biphenyl amides; BPAs; Protein kinase X-ray structure; Binding mode; Pharmacophore search; Focused screen; Virtual screening; Structure-based drug design; kinase selectivity
Mechanistic characterization for c-jun-N-Terminal Kinase 1α1
Keywords: کیناز MAP; JNK; MAP kinase; Kinetic mechanism; JIP; ATF2; c-jun
Effect of low pH on organization of the actin cytoskeleton in Saccharomyces cerevisiae
Keywords: کیناز MAP; Saccharomyces cerevisiae; Low pH; Cell wall stress; Actin polarization; Endocytosis; Mitogen activated protein kinase; PI(4,5)P2; Actin cytoskeleton; MAP kinase; Yeast;
Guanosine promotes B16F10 melanoma cell differentiation through PKC–ERK 1/2 pathway
Keywords: کیناز MAP; Guanosine; B16F10 differentiation; Melanoma; MAP kinase; Protein kinase C
Low density lipoproteins transactivate EGF receptor: Role in mesangial cell proliferation
Keywords: کیناز MAP; Low density lipoproteins; Oxidized-low density lipoproteins; MAP kinase; EGF receptor; Mesangial cell proliferation; Glomerular disease; Atherogenic lipoproteins
Signal transduction for formation/release of interleukin-8 caused by a PAR2-activating peptide in human lung epithelial cells
Keywords: کیناز MAP; Proteinase-activated receptor-2; MAP kinase; ERK; JNK; EGF receptor; Tyrosine kinase
Adenosine rescues glioma cells from cytokine-induced death by interfering with the signaling network involved in nitric oxide production
Keywords: کیناز MAP; Adenosine; Glioma; Nitric oxide; iNOS; Cytotoxicity; MAP kinase
AP1 binding site is another target of FGF2 regulation of bone sialoprotein gene transcription
Keywords: کیناز MAP; BSP; bone sialoprotein; FGF2; fibroblast growth factor 2; FRE; FGF response element; bp; base pair(s); nts; nucleotides; PKC; protein kinase C; PKA; cAMP dependent protein kinase; MAP kinase; mitogen activated protein kinase; MEK; MAP kinase kinase; Pit-1
C-reactive protein (CRP) increases VEGF-A expression in monocytic cells via a PI3-kinase and ERK 1/2 signaling dependent pathway
Keywords: کیناز MAP; C-reactive protein; VEGF; Atherosclerosis; MAP kinase
G-protein-dependent and -independent pathways regulate proteinase-activated receptor-2 mediated p65 NFκB serine 536 phosphorylation in human keratinocytes
Keywords: کیناز MAP; PAR-2; proteinase-activated receptor-2; PAR-2 AP; PAR-2 activating peptide; 2f-LIGKV-OH; 2-furoyl-LIGKV-hydroxyl; NFκB; nuclear factor kappa B; IKK; inhibitory kappa B kinase; PKC; protein kinase C; siRNA; small interfering ribonucleic acid; RNAi; ribonu
ATF-1 transcription factor regulates the expression of ccg-1 and cat-1 genes in response to fludioxonil under OS-2 MAP kinase in Neurospora crassa
Keywords: کیناز MAP; Catalase; Circadian rhythm; MAP kinase; Neurospora crassa; Two-component signal transduction
Somatostatin/somatostatin receptor signalling: Phosphotyrosine phosphatases
Keywords: کیناز MAP; Somatostatin; Somatostatin receptors; Phosphotyrosine phosphatase; Cell proliferation; Apoptosis; MAP kinase; SHP-1; SHP-2; DEP-1/PTPη
Signal transduction and gene expression in cultured accessory olfactory bulb neurons
Keywords: کیناز MAP; glutamate; norepinephrine; protein kinase C; MAP kinase; immediate-early gene; c-FosAOB, accessory olfactory bulb; CNC, agonist cocktail (clonidine, N-methyl-d-aspartic acid, cirazoline); DAG, diacylglycerol; Erk, extracellular signal regulated kinase; Et
Rapid CB1 cannabinoid receptor desensitization defines the time course of ERK1/2 MAP kinase signaling
Keywords: کیناز MAP; Cannabinoids; MAP kinase; Desensitization; Internalization; Phosphorylation; βarrestin;
1-Bromopropane induces macrophage activation via extracellular signal-regulated kinase 1/2 MAPK and NF-κB pathways
Keywords: کیناز MAP; 1-Bromopropane; Inducible nitric oxide synthase; NF-κB; MAP kinase;
Iron chelator differentially activates macrophage inflammatory protein-3α/CCL20 in immortalized and malignant human oral keratinocytes
Keywords: کیناز MAP; Iron chelator; Oral cancer; Immortalized keratinocytes; CCL20; MAP kinase; NF-κB
Activation of the progesterone-signaling pathway by methyl-β-cyclodextrin or steroid in Xenopus laevis oocytes involves release of 45-kDa Gαs
Keywords: کیناز MAP; Xenopus laevis; Oocyte; Ovarian follicle cells; Methyl-β-cyclodextrin; Progesterone; MAP kinase; Mos; Gαs; Oocyte maturation
Bacopa monniera ameliorates amnesic effects of diazepam qualifying behavioral-molecular partitioning
Keywords: کیناز MAP; amnesia; benzodiazepine; behavioral-molecular; Bacopa monniera; diazepam; water maze; cAMP; cyclic adenosine monophosphate; CREB; cAMP response element binding protein; ELT; escape latency time; ERK; extracellular signal-regulated kinase; iNOS; inducible
Quantitative measurement of epidermal growth factor receptor–mitogen-activated protein kinase signal transduction using a nine-plex, peptide-based immunoassay
Keywords: کیناز MAP; Immunoassay; Phosphorylation; Multiplex; MAP kinase; Epidermal growth factor receptor; MEK; ERK
The mitogen-activated protein kinase MpkA of Aspergillus fumigatus regulates cell wall signaling and oxidative stress response
Keywords: کیناز MAP; Aspergillus fumigatus; MAP kinase; Cell wall integrity; Oxidative stress; Virulence
Timing differences of signaling response in neuron cultures activated by glutamate analogue or free radicals
Keywords: کیناز MAP; Glutamate; MAP kinase; c-jun; p53; Oxidative stress
The scaffold protein JSAP1 regulates proliferation and differentiation of cerebellar granule cell precursors by modulating JNK signaling
Keywords: کیناز MAP; Granule cell precursor; MAP kinase; Scaffold protein; Signal transduction; Sonic hedgehog
Distinct MAPK signaling pathways, p21 up-regulation and caspase-mediated p21 cleavage establishes the fate of U937 cells exposed to 3-hydrogenkwadaphnin: Differentiation versus apoptosis
Keywords: کیناز MAP; 3-hydrogenkwadaphnin; Apoptosis; Caspase; Differentiation; Leukemia; MAP kinase; p21Cip/WAF1
Activation of p38 and JNK MAPK pathways abrogates requirement for new protein synthesis for phorbol ester mediated induction of select MMP and TIMP genes
Keywords: کیناز MAP; MMP; TIMP; Expression profiling; MAP kinase; Protein synthesis inhibition; Fibroblast
Adoptive passive transfer of rabbit β1-adrenoceptor peptide immune cardiomyopathy into the Rag2−/− mouse: Participation of the ER stress
Keywords: کیناز MAP; Cardiomyopathy; Endoplasmic reticulum; Metoprolol; Severe combined immunodeficiency mouse; Apoptosis; MAP kinase; Caspase-12 small-interfering RNA
Tristetraprolin regulates TNF TNF-α mRNA stability via a proteasome dependent mechanism involving the combined action of the ERK and p38 pathways
Keywords: کیناز MAP; MAP Kinase; Post-transcriptional regulation; Proteasome; TNF-α; Tristetraprolin;
The candidate MAP kinase phosphorylation substrate DPL-1 (DP) promotes expression of the MAP kinase phosphatase LIP-1 in C. elegans germ cells
Keywords: کیناز MAP; C. elegans; Germline; MAP kinase; LIP-1 phosphatase; E2F/DP;
Pharmacology of 5HT2C receptor-mediated ERK1/2 phosphorylation: Agonist-specific activation pathways and the impact of RNA editing
Keywords: کیناز MAP; Serotonin receptor; RNA editing; Stimulus trafficking; MAP kinase; Receptor theory
Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling
Keywords: کیناز MAP; ASK1; MAP kinase; p38; JNK; ROS; Apoptosis; Innate immunity; TLR4; Signalosome
Promotion of neurite outgrowth by fibroblast growth factor receptor 1 overexpression and lysosomal inhibition of receptor degradation in pheochromocytoma cells and adult sensory neurons
Keywords: کیناز MAP; FGFR1; MAP kinase; leupeptin; lysosome; sensory neurons; axonal growthDRG, dorsal root ganglia; ERK, extracellular signal-regulated kinase; FGF, fibroblast growth factor; FGFR, fibroblast growth factor receptor; FGFR1L, fibroblast growth factor receptor 1
IL-1β expression in Int407 is induced by flagellin of Vibrio cholerae through TLR5 mediated pathway
Keywords: کیناز MAP; Vibrio cholerae; IL-1β; Flagellin; Int407; TLR5; NF-κB; MAP kinase
Distinct activation patterns of EGF receptor signaling in the homoplastic evolution of eggshell morphology in genus Drosophila
Keywords: کیناز MAP; Drosophila melanogaster; Drosophila virilis; Drosophila melanica; Homoplastic evolution; Oogenesis; Eggshell; Dorsal appendage; EGFR signaling; MAP kinase; Rhomboid
Regulation of cardiac excitation and contraction by p21 activated kinase-1
Keywords: کیناز MAP; Protein phosphatase 2A; L-type Ca2+-channel; Sarcomeric protein phosphorylation; Ryanodine receptor; AC; denylate cyclase; Ad; adenovirus; BK channel; Ca2+-activated K+ currents; B(PR55); PP2A regulatory subunits; Bâ²(PR61); PP2A regulatory subunits; Bâ
Nitric oxide-proton stimulation of trigeminal ganglion neurons increases mitogen-activated protein kinase and phosphatase expression in neurons and satellite glial cells
Keywords: کیناز MAP; MAP kinase; MAP kinase phosphatase; trigeminal ganglion neurons; nitric oxide; protons; glia; CGRP; calcitonin gene-related peptide; DAPI; 4â²,6-diamidino-2-phenylindole; ERK; extracellular signal-regulated kinases; HBS; Hepes-buffered saline; Hepes; 4-(
Role of mTOR in anticancer drug resistance: Perspectives for improved drug treatment
Keywords: کیناز MAP; mTOR; Drug resistance; p70S6K1; PI3K; AKT; MAP kinase; VEGF; CCI-779; RAD001 (everolimus); AP-23573; Neurofibromatosis 1
Regulation of smooth muscle by inducible nitric oxide synthase and NADPH oxidase in vascular proliferative diseases
Keywords: کیناز MAP; Smooth muscle; Nitric oxide; iNOS; Superoxide; NADPH oxidase; Protein kinase C; MAP kinase; NF-κB; Free radicals
Dissecting lipid raft facilitated cell signaling pathways in cancer
Keywords: کیناز MAP; Cancer; Catenin; Caveolin-1; CD44; Ceramide; EGFR; Cholesterol; E-cadherin; Ezrin; FAS/CD95; FASL; Focal adhesion kinase; H-ras; Integrin; Lipid rafts; Matrix metalloproteinases (MMPs); Proteomics; Signal transduction; Sphingomyelin; uPA; uPAR; MAP kinase