Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; ERK, extracellular signal-regulated kinase; JNK, c-Jun N-terminal kinase; MAPKs, mitogen-activated protein kinases; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide dye; NSE, neuron-specific enolase; 15d-PGJ2, 15-deoxy-Δ12,14-prostagland
مقالات ISI MAPK ها، کیناز پروتئین پروتئین فعال Mitogen (ترجمه نشده)
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Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; 5-LO, 5-lipoxygenase; AA, arachidonic acid; cys-LTs, cysteinyl-leukotrienes; DMEM, Dulbecco's modified Eagle's medium; EIA, enzyme immunoassay; ERK, extracellular signal-regulated kinases; LTs, leukotrienes; MAPKs, mitogen-activated protein kinases; MPO,
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; Caffeine; Anti-inflammatory; LPS; NF-κB; MAPKsNF-κB, nuclear factor kappa B; MAPKs, mitogen-activated protein kinases; LPS, lipopolysaccharide; NO, nitric oxide; iNOS, nitric oxide synthase; COX-2, cyclooxygenase-2; IL, interleukin; IKK, IκB kinase; IκB,
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; 5-HT, 5-hydroxytryptamine; AD, Alzheimer's disease; ANOVA, analysis of variance; DMSO, dimethylsulfoxide; FST, forced-swim test; i.c.v., intracerebroventicular; i.p., intraperitoneal; LPS, lipopolysaccharide; MAPKs, mitogen-activated protein kinases; s.c.
Dextran sulfate sodium upregulates MAPK signaling for the uptake and subsequent intracellular survival of Brucella abortus in murine macrophages
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; Brucella abortus; Dextran sulfate sodium; Adhesion; Internalization; MacrophageDSS, dextran sulfate sodium; MAPKs, mitogen-activated protein kinases; BCVs, Brucella-containing vacuoles
Flavonoids from Radix Tetrastigmae inhibit TLR4/MD-2 mediated JNK and NF-κB pathway with anti-inflammatory properties
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; RTFs, flavonoids isolated from Radix Tetrastigmae; TLR4, Toll-like receptor 4; MD-2, myeloid differentiation factor-2; NF-κB, nuclear transcription factor-kappa B; MAPKs, mitogen-activated protein kinases; JNK, c-Jun N-terminal kinase; LPS, lipopolysaccha
The dichloromethane fraction from Mahonia bealei (Fort.) Carr. leaves exerts an anti-inflammatory effect both in vitro and in vivo
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; AP-1, activator protein-1; BALF, bronchoalveolar lavage fluid; ELISA, enzyme-linked immunosorbent assay; IRF-3, phosphoinositide-3-kinase-3; LPS, lipopolysaccharide; MAPKs, mitogen-activated protein kinases; MBL-CH, dichloromethane fraction from Mahonia b
Unsaturated but not saturated fatty acids induce transcriptional regulation of CCL2 in pancreatic acini. A potential role in acute pancreatitis
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; AP, acute pancreatitis; CCL2, chemokine (C–C motif) ligand 2; ERK, extracellular signal-regulated kinase; FA, fatty acid; JAK, Janus kinase; JNK, Jun NH2-terminal kinase; LA, linoleic acid; MAPKs, mitogen-activated protein kinases; NF-κB, nuclear factor-k
P38 participates in spermatogenesis and acrosome reaction prior to fertilization in Chinese mitten crab Eriocheir sinensis
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; MAPKs, mitogen-activated protein kinases; AR, acrosome reaction; ERK, extracellular signal-regulated kinase; JNK, c-Jun N-terminal kinase; MAPK14, p38α; Thr-Gly-Tyr, threonine–glycine–tyrosine; AV, acrosomal vesicle; AT, acrosomal tubule; AC, apical cap;
ALPK1 affects testosterone mediated regulation of proinflammatory cytokines production
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; ALPK1, alpha-kinase 1, alpha-protein kinase 1 or lymphocyte α-kinase; hALPK1, human ALPK1; mALPK1, endogenous mouse ALPK1; CMV, cytomegalovirus; EGFP, enhanced green fluorescent protein; MAPKs, mitogen-activated protein kinases; IL-1 beta, interleukin-1 b
The HIF-2alpha dependent induction of PAP and adenosine synthesis regulates glioblastoma stem cell function through the A2B adenosine receptor
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; PAP, prostatic acid phosphatase; HIF1α/2α, hypoxia-inducible factors 1α/2α; GSCs, glioblastoma stem cells; NSCs, neural stem cells; SCM, tumor stem cell propagating medium; MAPKs, mitogen-activated protein kinases; JNK, c-Jun N-terminal kinase; Akt/PKB, p
Fluvastatin inhibits growth and alters the malignant phenotype of the C6 glioma cell line
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; HMG-CoA, 3-hydroxy 3-methyl-glutaryl coenzyme A; MAPKs, mitogen-activated protein kinases; MMPs, matrix metalloproteinases; GPP, geranylpyrophosphate; GGPP, geranylgeranylpyrophosphate; FPP, farnesylpyrophosphate; BrdU, bromodeoxyuridine; MTT, 3-(4,5-dime
Arsenic induces reactive oxygen species-caused neuronal cell apoptosis through JNK/ERK-mediated mitochondria-dependent and GRP 78/CHOP-regulated pathways
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; ROS, reactive oxygen species; MAPKs, mitogen-activated protein kinases; JNK, c-Jun N-terminal kinase; ERK, extracellular signal-related kinase; Nrf2, nuclear-factor-E2-related factor 2; PARP, poly (ADP-ribose) polymerase; NAC, N-acetylcysteine; ER stress,
Saikosaponin A of Bupleurum chinense (Chaihu) elevates bone morphogenetic protein 4 (BMP-4) during hepatic stellate cell activation
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; BMP-4, bone morphogenetic protein-4; TGF-β, transforming growth factor-β; GDFs, growth differentiation factors; ALK, activin receptor-like kinase; MAPKs, mitogen-activated protein kinases; HSCs, hepatic stellate cells; ECM, extracellular matrix; α-SMA, sm
Cucurbitacin D is a new inflammasome activator in macrophages
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; THMs, traditional medicinal herbs; PECs, peritoneal exudate cells; BMDMs, bone marrow derived macrophages; MAPKs, mitogen-activated protein kinases; NALP3, NOD-like receptor family, pyrin domain containing 3; ASC, apoptosis-associated speck-like protein c
Implication of JNK pathway on tau pathology and cognitive decline in a senescence-accelerated mouse model
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; AD, Alzheimer's disease; Cdk5, cyclin-dependent kinase; GSK-3β, glycogen synthase kinase 3 beta; JNK, c-Jun N-terminal kinase; MAPKs, mitogen-activated protein kinases; NFT, neurofibrillary tangles; PHF, paired helical filaments; PP2A, protein phosphatase
Impact of non-thermal plasma treatment on MAPK signaling pathways of human immune cell lines
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; Caspase 3; Jurkat cells; MAPK signaling; Non-thermal plasma; Plasma medicine; THP-1 cells; Wound healingERK, extracellular signal-regulated kinase; HSP27, heat shock protein 27; JNK, c-Jun N-terminal kinase; MAPKs, mitogen-activated protein kinases; MEK,
Anti-inflammatory effect of the hexane fraction from Orostachys japonicus in RAW 264.7 cells by suppression of NF-κB and PI3K-Akt signaling
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; LPS, lipopolysaccharide; NO, nitric oxide; TLR4, toll like receptor 4; iNOS, inducible nitric oxide synthase; COX-2, cyclooxygenase-2; NF-κB, nuclear factor-kappa B; IκBα, inhibitory factor kappa B alpha; MAPKs, mitogen-activated protein kinases; JNK, c-J
Requirement of a dynein light chain in transforming growth factor β signaling in zebrafish ovarian follicle cells
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; TGFβ, transforming growth factor β; TβRII, TGFβ receptor II; TβRI, TGFβ receptor I; RSmads, receptor-activated Smads; MAPKs, mitogen-activated protein kinases; JNK, c-Jun N-terminal kinase; Erk, extracellular signal-regulated kinase; zkm23, zebrafish km23
Involvement of oxidative stress-induced ERK/JNK activation in the Cu2+/pyrrolidine dithiocarbamate complex-triggered mitochondria-regulated apoptosis in pancreatic β-cells
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; DM, diabetes mellitus; PDTC, pyrrolidine dithiocarbamate; LPO, lipid peroxidation; GSH, glutathione; PARP, poly (ADP-ribose) polymerase; NAC, N-acetylcysteine; MAPKs, mitogen-activated protein kinases; ERK, extracellular signal-regulated kinases; JNK, c-j
NF-κB in the mechanism of brain edema in acute liver failure: Studies in transgenic mice
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; ALF, acute liver failure; ALT, alanine aminotransferase; AST, aspartate aminotransferase; iNOS, nitric oxide synthase; MAPKs, mitogen-activated protein kinases; NF-κB, nuclear factor-κB; NOX, NADPH oxidase; TAA, thioacetamide; Tg, transgenic; WT, wild typ
Mitochondrial ERK plays a key role in delta-opioid receptor neuroprotection against acute mitochondrial dysfunction
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; DOR, delta-opioid receptor; NaN3, sodium azide; DADLE, [d-Ala2, d-Leu5] enkephalin; MAPKs, mitogen-activated protein kinases; NTI, naltrindole; 5-HD, 5-hydroxydecanoic acid sodium salt; LDH, lactate dehydrogenase; TMRE, tetramethylrhodamine ethyl ester; R
Involvement of oxidative stress-mediated ERK1/2 and p38 activation regulated mitochondria-dependent apoptotic signals in methylmercury-induced neuronal cell injury
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; LPO, lipid peroxidation; PARP, poly (ADP-ribose) polymerase; NAC, N-acetylcysteine; MAPKs, mitogen-activated protein kinases; ERK, extracellular signal-regulated kinases; JNK, c-Jun N-terminal kinases; MMP, mitochondrial membrane potential; ROS, reactive
Arsenic induces pancreatic β-cell apoptosis via the oxidative stress-regulated mitochondria-dependent and endoplasmic reticulum stress-triggered signaling pathways
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; ROS, reactive oxygen species; MDA, malondialdehyde; MAPKs, mitogen-activated protein kinases; PARP, poly(ADP-ribose) polymerase activation; ER stress, endoplasmic reticulum stress; GRP, glucose-regulated protein; CHOP, C/EBP homologue protein; XBP-1, X-bo
Taurine suppresses doxorubicin-triggered oxidative stress and cardiac apoptosis in rat via up-regulation of PI3-K/Akt and inhibition of p53, p38-JNK
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; CAT, catalase; DOX, doxorubicin; GSH, glutathione; GSSG, glutathione disulfide; GPx, glutathione peroxidase; HDL, high-density lipoprotein; LDH, lactate dehydrogenase; MDA, malondialdehyde; MAPKs, mitogen-activated protein kinases; NF-κB, nuclear factor k
Mechanisms of hepatocyte growth factor-mediated signaling in differentiation of pancreatic ductal epithelial cells into insulin-producing cells
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; PDEC, pancreatic ductal epithelial cell; HGF, hepatocyte growth factor; MAPKs, mitogen-activated protein kinases; PI3K, the phosphoinositide-3 kinase; MEK, MAP kinase kinase; ERK, extracellular signal-regulated protein kinase; JNK, c-Jun N-terminal kinase
Hypoxia induces up-regulation of progranulin in neuroblastoma cell lines
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; FTD, frontotemporal dementia; GLUT-1, glucose transporter 1; GSH, reduced glutathione; GSSG, oxidized glutathione; H2O2, hydrogen peroxide; MAPKs, mitogen-activated protein kinases; MEK, (MAPK)/extracellular signal-regulated kinase kinase; PGRN, progranul
Chitosan oligosaccharides suppressant LPS binding to TLR4/MD-2 receptor complex
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; TLR4, Toll-Like receptor 4; MD-2, myeloid differentiation factor 2; COS, chitosan oligosaccharides; LPS, lipopolysaccharide; PMB, polymyxin B; MAPKs, mitogen-activated protein kinases; NF-κB, nuclear factor-κBLPS; IL-1β; Chitosan oligosaccharides; MAPKs;
Inhibition of cadmium-induced apoptosis by glutathione S-transferase P1 via mitogen-activated protein kinases and mitochondrial pathways
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; GSTP1, glutathione S-transferase P1; MAPKs, mitogen-activated protein kinases; ERK, extracellular signal-regulated kinase; JNK, c-Jun N-terminal kinase; ROS, reactive oxygen species; PI, propidium iodide; ΔΨm, mitochondria transmembrane potentialApoptosis
The classical NFκB pathway is required for phloroglucinol-induced activation of murine lymphocytes
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; NFκB, nuclear factor-κB; MAPKs, mitogen-activated protein kinases; PG, phloroglucinol; MMP, matrix metalloproteinases; MTT, 3-[4,5-dimethylthiazole-2-yl]-2,5 diphenyltetrazoliumbromide; DMSO, dimethylsulfoxide; TPCK, N-p-Tosyl-L-phenylalanine chloromethyl
Ephedrannin A and B from roots of Ephedra sinica inhibit lipopolysaccharide-induced inflammatory mediators by suppressing nuclear factor-κB activation in RAW 264.7 macrophages
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; LPS, lipopolysaccharide; NO, nitric oxide; TNF-α, tumor necrosis factor alpha; IL-1β, interleukin-1 beta; IKK-β, IκB kinase beta; NF-κB, nuclear factor-kappa B; MAPKs, mitogen-activated protein kinases; MKK, MAPK kinase; IFN-γ, interferon gamma; iNOS, ind
Flavocoxid counteracts muscle necrosis and improves functional properties in mdx mice: A comparison study with methylprednisolone
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; AA, arachidonic acid; CK, creatine kinase; COX, cyclooxygenase; GRAS, generally recognized as safe; H&E, hematoxylin-eosin; I-κB, inhibitory protein κB; IKK, I-κB kinase; LOX, lipoxygenase; LTB4, leukotriene B4; MAPKs, mitogen-activated protein kinases; N
Ginkgo biloba extract confers protection from cigarette smoke extract-induced apoptosis in human lung endothelial cells: Role of heme oxygenase-1
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; Ginkgo biloba extract; Cigarette smoke; Heme oxygenase-1; Oxidative stress; Apoptosis; Endothelial cellsEGb, Ginkgo biloba extract; CSE, cigarette smoke extract; HPAECs, human pulmonary artery endothelial cells; MAPKs, mitogen-activated protein kinases; N
Oxidized LDL affects smooth muscle cell growth through MAPK-mediated actions on nuclear protein import
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; LDL, Low density lipoprotein; oxLDL, oxidized low density lipoprotein; naLDL, native low density lipoprotein; VSMC, vascular smooth muscle cells; NPI, nuclear protein import; NPC, nuclear pore complex; MAPKs, mitogen-activated protein kinases; PCNA, Proli
Tissue distribution and proinflammatory cytokine gene expression following acute oral exposure to deoxynivalenol: Comparison of weanling and adult mice
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; AUCs, areas under the curve; DON, deoxynivalenol; HS, high sensitivity; MAPKs, mitogen-activated protein kinases; PBS, phosphate buffered saline; TDIs, tolerable daily intakesDeoxynivalenol; Trichothecene; Mycotoxin; Age; Toxicokinetics; Cytokine
Serum starvation induces H2AX phosphorylation to regulate apoptosis via p38 MAPK pathway
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; IR, ionizing radiation; UV, ultraviolet; MEFs, mouse embryonic fibroblasts; MAPKs, mitogen-activated protein kinases; TBST, Tris-buffered saline containing Tween 20H2AX; Apoptosis; p38; MAPK
Knockdown of Snail, a novel zinc finger transcription factor, via RNA interference increases A549 cell sensitivity to cisplatin via JNK/mitochondrial pathway
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; MAPKs, mitogen-activated protein kinases; JNK, c-Jun N-terminal kinase; NSCLC, non-small-cell lung cancer; EMT, epithelial-mesenchymal transition; TNFR, tumor necrosis factor receptorsSnail; RNA interference; Cisplatin; Sensitivity; Epithelial-mesenchymal
Programmed cell death and differential JNK, p38 and ERK response in a prenatal acute hypoxic hypoxia model
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; ED, embryonic day; p-h, post-hypoxia; MAPKs, mitogen-activated protein kinases; SAPKs, stress-activated protein kinasesMAPKs; Hypoxia; Programmed cell death; Chick optic lobe; CNS development
Dipyrithione inhibits lipopolysaccharide-induced iNOS and COX-2 up-regulation in macrophages and protects against endotoxic shock in mice
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; PTS2, dipyrithione; LPS, lipopolysaccharide; iNOS, inducible nitric oxide synthase; NO, nitric oxide; COX-2, cyclooxygenase-2; STAT1, signal transducers and activators of transcription 1; MAPKs, mitogen-activated protein kinases; NF-κB, nuclear factor κB;
The activation of ERK1/2 and p38 mitogen-activated protein kinases is dynamically regulated in the developing rat visual system
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; dLGN, dorso-lateral geniculate nucleus; ERK1/2, extracellular signal-regulated kinases 1/2; INTOD, integrated optical density; JNK/SAPK, c-Jun amino-terminal kinases or stress-activated protein kinases; MAPKs, mitogen-activated protein kinases; p38 kinase
Specific cerebral heat shock proteins and histamine receptor cross-talking mechanisms promote distinct lead-dependent neurotoxic responses in teleosts
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; Cim, cimetidine; CP, central posterior thalamic nucleus; Dm, dorsomedial telencephalic region; DP, dorsal posterior thalamic nucleus; HA, histamine; HSP, heat shock protein; MAPKs, mitogen-activated protein kinases; MAT, maximum acceptable toxicant; NAT,
Anticancer mechanisms of YC-1 in human lung cancer cell line, NCI-H226
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; bFGF, basic fibroblast growth factor; DMSO, dimethyl sulfoxide; ERK, extracellular signal-regulated kinase; FBS, fetal bovine serum; FACS, fluorescence-activated cell sorter; JNK, c-Jun NH2-terminal kinase; MAPKs, mitogen-activated protein kinases; MMPs,
Influence of deoxynivalenol on NF-κB activation and IL-8 secretion in human intestinal Caco-2 cells
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; DON, deoxynivalenol; MAPKs, mitogen-activated protein kinases; NF-κB, nuclear factor κB; IBDs, inflammatory bowel diseases; IL-1β, interleukin-1β; TNF-α, tumor necrosis factor α; LPS, lipopolysaccharides; IL-8, interleukin 8; IκB, inhibitor of κB; LDH, la
Inhibitors of c-Jun N-terminal kinases—JuNK no more?
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; CVB3, Coxsackievirus B3; HIV, Human immunodeficiency virus; JNKs, c-Jun N-terminal kinases; MAPKs, mitogen-activated protein kinases; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PARP-1, poly(ADP-ribose) polymerase-1; PDB, Protein DataBase; ROS, Re
Some advances in plant stress physiology and their implications in the systems biology era
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; LEA, late-embryogenesis abundant protein; MAPKs, mitogen-activated protein kinases; ROS, reactive oxygen species; ABA, abiscisic acid; PA, phosphatidic acid; POD, peroxidase; CAT, catalase; SOD, superoxide dismutase; MDA, malondialdehydeCrop; Stress physi
Eleutherococcus senticosus extract attenuates LPS-induced iNOS expression through the inhibition of Akt and JNK pathways in murine macrophage
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; LPS, lipopolysaccharides; MAPKs, mitogen-activated protein kinases; iNOS, inducible nitric oxide synthase; COX-2, cyclooxygenase-2; JNK, c-Jun N-terminal kinase; Akt, anti-apoptosis mediator protein kinase B; ERK, extracellular signal-regulated kinasesEle
The nitric oxide prodrug, V-PYRRO/NO, mitigates arsenic-induced liver cell toxicity and apoptosis
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; ERKs, extracellular signal-regulated kinases; cGMP, cyclic guanosine 3′,5′-monophosphate; LC50, lethal concentration 50%; JNK, c-Jun N-terminal kinase; MAPKs, mitogen-activated protein kinases; MT, metallothionein; NO, nitric oxide; TRL, 1215, rat liver e
Mycotoxin fumonisin B1 alters cellular redox balance and signalling pathways in rat liver and kidney
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; FB1, fumonisin B1; ROS, reactive oxygen species; GSH, glutathione; GSSG, glutathione disulphide; γ-GCS, γ-glutamylcysteine synthetase; MAPKs, mitogen-activated protein kinases; Hsps, heat shock proteins; ERK, extracellular signal-regulated kinase; JNK, c-
Cellular response to infrared radiation involves retrograde mitochondrial signaling
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; DCF, 2’,7-dichlorofluorescein; DCFDA, 2’,7-dichlorofluorescein diacetate; ETC, electron transport chain; MAPKs, mitogen-activated protein kinases; MMP-1, matrix metalloproteinase-1; PBS, phosphate-buffered saline; PGC-1, peroxisome proliferator-activated
Curcumin, a Curcuma longa constituent, acts on MAPK p38 pathway modulating COX-2 and iNOS expression in chronic experimental colitis
Keywords: MAPK ها، کیناز پروتئین پروتئین فعال Mitogen; CD, Crohn's disease; COX, Cyclo-oxygenase; CUR, Curcumin; HETAB, Hexadecyl-trimethylammonium bromide; IBD, Inflammatory bowel disease; IFN, Interferon; IL, Interleukin; JNK, c-Jun N-terminal kinase; MAPKs, Mitogen-activated protein kinases; MPO, Myelopero