دانلود مقالات ISI درباره Mdc1 + ترجمه فارسی

ReviewTranscription and DNA Damage: Holding Hands or Crossing Swords?

Keywords: DSBs; DNA double-strand breaks; DDR; DNA damage response; MRN; MRE11-RAD50-NBS1; ATM; ataxia telangiectasia mutated; MDC1; mediator of DNA-damage checkpoint; 53BP1; p53-binding protein; NHEJ; non-homologous end joining; ncRNA; non-coding RNA; HR; homo

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

MDC1-AS, an antisense long noncoding RNA, regulates cell proliferation of glioma

Keywords: Glioma; Long non-coding RNA MDC1-AS; MDC1; Cell proliferation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Mdc1 modulates the interaction between TopBP1 and the MRN complex during DNA damage checkpoint responses

Keywords: Mdc1; TopBP1; MRN complex; Nbs1; DNA damage checkpoint; DSB; double-stranded DNA break; Mdc1; mediator of DNA damage checkpoint protein 1; Chk1; checkpoint kinase 1; ATM; ataxia-telangiectasia mutated; ATR; ATM and Rad3-related; IR; ionizing radiation; si

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Emerging role of protein phosphatases changes the landscape of phospho-signaling in DNA damage response

Keywords: 53BP1; p53 binding protein 1; ATM; ataxia-telangiectasia mutated; ATR; ataxia telangiectasia and Rad3 related; BLM; blooms syndrome RecQ helicase-like, human homolog of SGS1; BRCA1; breast cancer 1, early onset; CDC; cell division cycle; CDK; cyclin depen

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Increased CD1c+ mDC1 with mature phenotype regulated by TNFα-p38 MAPK in autoimmune ocular inflammatory disease

Keywords: mDC1; myeloid dendritic cells 1; HCs; healthy controls; MoDCs; monocyte-derived dendritic cells; PBMCs; peripheral blood mononuclear cells; Th; T helper; DCs; dendritic cells; mDCs; myeloid dendritic cells; pDCs; plasmacytoid dendritic cells; Lin1; lineag

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Protein kinase CK2 is required for the recruitment of 53BP1 to sites of DNA double-strand break induced by radiomimetic drugs

Keywords: DSBs; DNA double-strand breaks; NHEJ; non-homologous end-joining; HR; homologous recombination; NCS; neocarzinostatin; ATM; ataxia telangiectasia mutated; MDC1; mediator of DNA damage checkpoint; 53BP1; p53-binding protein 1; BRCA1; breast cancer type 1 s

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Histone deacetylase inhibitor (HDACI) mechanisms of action: Emerging insights

Keywords: HDAC inhibitor; DNA damage response; DNA repair; Cell cycle checkpoints; Apoptosis; Rational combinations; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; APAF-1; apoptotic protease activating factor 1; ASK1; apoptosis signal-regulating ki

دانلود رایگان متن کامل مقاله ISI 78 صفحه سال انتشار : 2014 سفارش ترجمه

Targeting DNA damage response: Threshold, chromatin landscape and beyond

Keywords: DSBs; double strand breaks; γ-H2AX; phosphorylation of histone variant H2AX in Ser139; SUMO; small ubiquitin modifier; ROS; reactive oxygen species; IR; ionizing radiation; Tip60; Tat-interactive 60; HAT; histone acetyltransferase; HDAC; histone deacetyl

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

DNA double‐strand break response in stem cells: Mechanisms to maintain genomic integrity

Keywords: ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related protein; BRCA1; breast cancer type 1 susceptibility protein; CtBP; C-terminal binding protein; CtIP; CTBP interacting protein; DDR; DNA damage response; DNA-PK; DNA-dependent

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Double strand break repair functions of histone H2AX

Keywords: Mammalian DSB repair; H2AX; MDC1; 53BP1; BRCA1; Mre11/Rad50/Nbs1; Histone code; Homologous recombination; Non-homologous end joining; Single strand annealing

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Dimerization, but not phosphothreonine binding, is conserved between the forkhead-associated domains of Drosophila MU2 and human MDC1

Keywords: MU2, mutator 2; MDC1, mediator of DNA damage checkpoint protein 1; FHA, forkhead-associated; DDR, DNA damage response; DSB, double-strand breakX-ray crystallography; DNA damage response; Forkhead-associated domain; MDC1; Molecular evolution

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Three-dimensional imaging reveals the spatial separation of γH2AX–MDC1–53BP1 and RNF8–RNF168–BRCA1-A complexes at ionizing radiation-induced foci

Keywords: DNA damage; Ionizing radiation; Nuclear foci; γH2AX; MDC1; RNF8; RNF168; 53BP1; Abraxas (CCDC98); BRCA1; BRCC36; Merit40 (NBA1); RAP80

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The application of modular protein domains in proteomics

Keywords: pTyr; phosphotyrosine; PTM; post-translational modification; MS; mass spectrometry; PSSM; position specific scoring matrix; SH2; Src homology 2; SH3; Src homology 3; WW; tryptophan tryptophan; PDZ; post synaptic density protein 95-disks large protein 4-zo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

The in vivo dynamic interplay of MDC1 and 53BP1 at DNA damage-induced nuclear foci

Keywords: DNA damage; Ionizing radiation; Nuclear foci; Dynamics; MDC1; 53BP1;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

MDC1 is ubiquitylated on its tandem BRCT domain and directly binds RAP80 in a UBC13-dependent manner

Keywords: BRCT; BRCA1 C-terminus; DDR; DNA damage response; DSB; DNA double-strand break; DUB; deubiquitinase; FHA; forkhead associated; GST; glutathione S-transferase; a.a.; amino acids; NCS; neocarzinostatin; IP; immunoprecipitate; IR; ionizing radiation; PTM; po

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

DNA repair in the context of chromatin: New molecular insights by the nanoscale detection of DNA repair complexes using transmission electron microscopy

Keywords: DNA double-strand break repair; Non-homologous end-joining; Transmission electron microscopy; Ku70–Ku80 heterodimer; γH2AX; MDC1; 53BP1

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Radiation-Induced Survivin Nuclear Accumulation is Linked to DNA Damage Repair

Keywords: Survivin; Colorectal cancer; DNA repair; DNA-PKcs; MDC1; Phospho-histone H2AX;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Many roads lead to primary autosomal recessive microcephaly

Keywords: 53BP1; tumor-suppressor protein p53 binding protein 1; APC; anaphase-promoting complex; ASPM; abnormal spindle-like, microcephaly associated protein; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and RAD3-related protein; BACH1; BRCA1-ass

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2010 سفارش ترجمه

14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response

Keywords: DNA damage response; Phosphopeptide-binding; FHA domain; BRCT domain; 14-3-3; BRCA1; MDC1; 53BP-1; RNF8

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Allergen-enhanced thrombomodulin (blood dendritic cell antigen 3, CD141) expression on dendritic cells is associated with a TH2-skewed immune response

Keywords: Dendritic cells; thrombomodulin; allergy; BDCA3; Blood dendritic cell antigen 3/thrombomodulin; DC; Dendritic cell; FACS; Fluorescence-activated cell sorting; HDM; House dust mite; mDC1; Myeloid dendritic cell type 1; mDC2; Myeloid dendritic cell type 2;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

The radioprotector Bowman–Birk proteinase inhibitor stimulates DNA repair via epidermal growth factor receptor phosphorylation and nuclear transport

Keywords: BBI; EGFR; TP53; DNA repair; MDC1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Nbs1-dependent binding of Mre11 to adenovirus E4 mutant viral DNA is important for inhibiting DNA replication

Keywords: Adenovirus; E4 mutant; DNA replication; DNA binding; DNA damage response; MRN complex; Mdc1

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

RAP80 and RNF8, key players in the recruitment of repair proteins to DNA damage sites

Keywords: Double-strand breaks; RAP80; RNF8; Ubiquitination; CCDC98/Abraxas; BRCA1; UIM; MDC1

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Protein trafficking in response to DNA damage

Keywords: ARF; alternative reading frame; ATM; ataxia telangiectasia mutated kinase; ATR; ataxia telangiectasia RAD3-related kinase; DSB; DNA double-strand breaks; Mdm2; murine double minute; MMC; mitomycin C; MDC1; Mediator of DNA damage checkpoint protein 1; PARP

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Genistein-induced neuronal apoptosis and G2/M cell cycle arrest is associated with MDC1 up-regulation and PLK1 down-regulation

Keywords: SK-N-MC Neuroblastoma; Genistein; Apoptosis; Cell cycle arrest; MDC1; PLK1; Chk2

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

The DNA damage response during an unperturbed S-phase

Keywords: A-T; Ataxia-Telangiectasia; ATM; Ataxia-Telangiectasia Mutated; ATR; ATM and Rad3 related (mec1); DSBs; double-strand breaks; ssDNA; single strand DNA; PIKK; phosphoinositol kinase like kinase; IR; ionizing radiation; UV; ultraviolet; HU; hydroxyure

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

The cellular Mre11 protein interferes with adenovirus E4 mutant DNA replication

Keywords: Adenovirus; E4 mutant; DNA replication; Double strand break repair; Mre11; Damage response; Mdc1

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Differences in DNA double strand breaks repair in male germ cell types: Lessons learned from a differential expression of Mdc1 and 53BP1

Keywords: Mdc1; 53BP1; Rad51; Meiosis; Spermatogenesis; DNA repair;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

γH2AX and MDC1: Anchoring the DNA-damage-response machinery to broken chromosomes

Keywords: DNA double-strand breaks; Chromatin; Histone H2AX; MDC1; DNA damage checkpoint; DNA repair; Foci; Genome stability

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه