Keywords: ANOVA; analysis of variance; CS; conditioned stimulus; CTA; conditioned taste aversion; MDZ; midazolam; NAL; naloxone; PBN; parabrachial nucleus; PBS; phosphate buffered saline; TR; taste reaction; US; unconditioned stimulus; Saccharin; Lithium chloride;
مقالات ISI (ترجمه نشده)
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Keywords: Anxiety; Benzodiazepine; Electrical stimulation; Fear; Inferior colliculus; Midazolam; BZD; Benzodiazepine; EAS; Encephalic Aversion System; EPM; Elevated plus maze; ICd; dorsal part of inferior colliculus; ICv; ventral part of inferior colliculus; MDZ; M
Keywords: BLM; Bilayer Lipid Membrane; MDZ; Midazolam; MDZH+Clâ; Midazolam Hydrochloride; FDD; Frequency Dependent Dispersion; Midazolam; BLM; Nonspecific action; Impedance spectroscopy; Capacitance;
Keywords: CLP; clonazepam; CLZ; clorazepate; DZP; diazepam; FB; felbamate; LEV; levetiracetam; LTG; lamotrigine; LZP; lorazepam; MDZ; midazolam; MTX; methosuximide; OXC; oxcarbazepine; PB; phenobarbital; PD; pyridoxine; PHT; phenytoin; PT; pentobarbital; TPM; topir
A UHPLC-MS/MS method coupled with liquid-liquid extraction for the quantitation of phenacetin, omeprazole, metoprolol, midazolam and their metabolites in rat plasma and its application to the study of four CYP450 activities
Keywords: ACE; acetaminophen; PHE; phenacetin; OHOME; 5â²-hydroxy omeprazole; OME; omeprazole; OHMET; α-hydroxy metoprolol; MET; metoprolol; OHMDZ; 1â²-hydroxy midazolam; MDZ; midazolam; CYP450; Probe drug; Metabolite; UHPLC-MS/MS; DDI; 3-n-butylphthalide;
Ketamine-induced hypnosis and neuroplasticity in mice is associated with disrupted p-MEK/p-ERK sequential activation and sustained upregulation of survival p-FADD in brain cortex: Involvement of GABAA receptor
Keywords: Ketamine; Hypnosis; Neuroplasticity; MEK-ERK; FADD; NF-kB; Mouse brain; CNS; central nervous system; Elk-1; nuclear substrate belonging to the family of ETS domain-containing transcription factors; ERK; extracellular signal-regulated kinase; FADD; Fas-ass
Effects of tomato juice on the pharmacokinetics of CYP3A4-substrate drugs
Keywords: Food-drug interactions; Tomato juice; Grapefruit juice; Nifedipine; Midazolam; Pharmacokinetic interactions; TJ; tomato juice; GFJ; grapefruit juice; NFP; nifedipine; MDZ; midazolam; AUC; area under the concentration-time curve; CYP; cytochrome P450;
Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity
Keywords: MPS; microphysiological system; LDH; lactate dehydrogenase; ALT; alanine aminotransferase; BNF; beta-naphthoflavone; Rif; rifampin; EROD; ethoxyresorufin-O-deethylase; CYPs; cytochrome P450s; HNF4α; hepatocyte nuclear factor 4 alpha; MDZ; midazolam; AFB;
Challenges in assignment of allosteric effects in cytochrome P450-catalyzed substrate oxidations to structural dynamics in the hemoprotein architecture
Keywords: Cytochrome P450; Allosteric effects; Cooperativity; Key determinants; Molecular modeling; 1PB; 1-pyrenebutanol; 4MP; 4-methylpyrazole; 7BQ; 7-benzyloxyquinoline; 7EC; 7-ethoxycoumarin; 7EFC; 7-ethoxy-4-trifluoromethylcoumarin; 9AP; 9-aminophenanthrene; 9E
Simulations of Cytochrome P450 3A4-Mediated Drug-Drug Interactions by Simple Two-Compartment Model-Assisted Static Method
Keywords: bioavailability; cytochrome P450; drug interaction; dynamic simulation; first pass metabolism; hepatic clearance; intestinal metabolism; pharmacokinetics; simulations; parallel tube model; Ae (Ae,oral); dose fractions of urinary excreted unchanged drug af
Role of cytochrome P450-mediated metabolism and identification of novel thiol-conjugated metabolites in mice with phenytoin-induced liver injury
Keywords: ABT; 1-aminobenzotriazole; ALT; alanine aminotransferase; BSO; l-buthionine-(S,R)-sulfoximine; Cys; cysteine; DPH; phenytoin; γ-GCS; γ-glutamilcysteine synthetase; 4â²-HPPH; 5-(4â²-hydroxyphenyl)-5-phenylhydantoin; MDZ; midazolam; NAC; N-acetylcystein
Glycyrrhizin accelerates the metabolism of triptolide through induction of CYP3A in rats
Keywords: TWHF; Tripterygium wilfordii Hook F; TP; triptolide; GL; glycyrrhizin; KCZ; ketoconazole; MDZ; midazolam; OH-MDZ; 1׳-hydroxymidazolam; IS; internal standard; AUCâ; area under curve from dosing time extrapolated to infinity; MRTâ; mean residence time
Modulation of haloperidol-induced catalepsy in rats by GABAergic neural substrate in the inferior colliculus
Keywords: IC; inferior colliculus; MDZ; midazolam; MK-801; (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]-cyclohepten-5,10-imine maleate; NMDA; N-methyl-d-aspartate; PD; Parkinson's disease; SNpr; substantia nigra pars reticulata; haloperidol; catalepsy; GABA; midazo
Vagus nerve stimulation for drug-resistant Epilepsia Partialis Continua: Report of four cases
Keywords: EPC; Epilepsia Partialis Continua; VNS; vagus nerve stimulation; RE; Rasmussen's encephalitis; ACDs; anticonvulsant drugs; SE; status epilepticus; MDZ; midazolam; CBZ; carbamazepine; OXC; oxcarbamazepine; TPM; topiramate; LVT; leviracetam; VPA; valproic a
Induction of cytochrome P450 3A by Shexiang Baoxin Pill and its main components
Keywords: P450; cytochrome P450; CYP3A; cytochrome P450 3A; DDI; drug-drug interaction; TCM; traditional Chinese medicine; SBP; Shexiang Baoxin Pill; MDZ; midazolam; CHD; coronary heart diseases; MUS; muscone; TES; testosterone; GRf; ginsenoside Rf; GRg1; ginseno
Prenatal ethanol exposure attenuates GABAergic inhibition in basolateral amygdala leading to neuronal hyperexcitability and anxiety-like behavior of adult rat offspring
Keywords: anxiety-like behavior; prenatal EtOH exposure; basolateral amygdale complex; GABA; evoked potential; dysinhibition; ACSF; artificial cerebrospinal fluid; BEC; blood ethanol contentration; BLA; basolateral amygdala complex; BMI; bicuculline methiodide; EC;
Differential effect of Shenmai injection, a herbal preparation, on the cytochrome P450 3A-mediated 1â²-hydroxylation and 4-hydroxylation of midazolam
Keywords: SMI; Shenmai injection; MDZ; midazolam; 1â²-OH MDZ; 1â²-hydroxymidazolam; 4-OH MDZ; 4-hydroxymidazolam; TG; total ginsenoside; OTS; ophiopogon total saponins; OTF; ophiopogon total flavone; KTZ; ketoconazole; RLM; rat liver microsomes; HLM; human liver