Lactulose: Production, purification and potential applications
Keywords: مکانیسم عمل; Lactulose; Production; Purification; Analysis; Mechanism of action; Applications;
مقالات ISI مکانیسم عمل (ترجمه نشده)
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Atomic force microscopy analysis shows surface structure changes in carvacrol-treated bacterial cells
Keywords: مکانیسم عمل; Atomic force microscopy; Carvacrol; Cell envelope; Essential oils; Food-borne bacteria; Mechanism of action;
Virucidal mechanism of action of NVC-422, a novel antimicrobial drug for the treatment of adenoviral conjunctivitis
Keywords: مکانیسم عمل; Adenovirus; Conjunctivitis; Mechanism of action; Virucidal; Antimicrobial;
Recent advances in understanding the antibacterial properties of flavonoids
Keywords: مکانیسم عمل; Flavonoids; Antibacterial; Structure–activity; Mechanism of action; Synergy; Antivirulence
Plant cell membrane as a marker for light-dependent and light-independent herbicide mechanisms of action
Keywords: مکانیسم عمل; Plasma membrane; Mode of action; Herbicide; Mechanism of action; Light-dependent; Light-independent; Electrolyte leakage; Conductivity; Peroxidation;
Potential biocontrol activity of a strain of Pichia guilliermondii against grey mold of apples and its possible modes of action
Keywords: مکانیسم عمل; Biological control; Botrytis cinerea; Hydrolytic enzymes; Induced resistance; Mechanism of action; Pichia guilliermondii
Organometallic ruthenium-based antitumor compounds with novel modes of action
Keywords: مکانیسم عمل; Ruthenium complexes; Mechanism of action; Cancer
Antiepileptic drug therapy: Does mechanism of action matter?
Keywords: مکانیسم عمل; Antiepileptic drugs; Mechanism of action; Epileptogenesis; Antiepileptogenesis; Disease modification; Epilepsy; Pharmacokinetics; Pharmacodynamics; Interactions; Treatment;
A review of topical negative pressure therapy in wound healing: sufficient evidence?
Keywords: مکانیسم عمل; Topical negative pressure therapy; Surgical wounds; Mechanism of action
Antiepileptic drug therapy the story so far
Keywords: مکانیسم عمل; Antiepileptic drugs; Mechanism of action; Epilepsy; Pharmacoresistance; Prognosis
In vitro determination of the uterine stimulatory effect of the aqueous leaf extract of Ficus exasperata
Keywords: مکانیسم عمل; Ficus exasperata (Moraceae); Uterus; Mechanism of action; Phentolamine; Diphenhydramine; Verapamil; Atropine; Indomethacin;
Spanish women's attitudes towards post-fertilization effects of birth control methods
Keywords: مکانیسم عمل; Mechanism of action; Informed choice; Contraception
Antiviral efficacy of EICAR against canine distemper virus (CDV) in vitro
Keywords: مکانیسم عمل; Canine distemper virus; Paramyxoviridae; Antiviral activity; Ribavirin; EICAR; Mechanism of action
2-Methoxyestradiol—Biology and mechanism of action
Keywords: مکانیسم عمل; 2-Methoxyestradiol; Biology; Mechanism of action
Studies on the action mechanism of benzoylurea insecticides to inhibit the process of chitin synthesis in insects: A review on the status of research activities in the past, the present and the future prospects
Keywords: مکانیسم عمل; Diflubenzuron; Mechanism of action; Sulfonylurea receptor; Insect chitin synthesis; Target site;
Enterobacterial tumor colonization in mice depends on bacterial metabolism and macrophages but is independent of chemotaxis and motility
Keywords: مکانیسم عمل; Cancer; Enterobacteria; Chemotaxis; Macrophage; Metabolism; Mechanism of action
Superinduction of estrogen receptor mediated gene expression in luciferase based reporter gene assays is mediated by a post-transcriptional mechanism
Keywords: مکانیسم عمل; Estrogen reporter gene assay; Genistein; Superinduction; Mechanism of action; Metabolism; Proliferation; Artefact
Mechanism of action of insecticidal secondary metabolites of plant origin
Keywords: مکانیسم عمل; Chemical ecology; Insecticide; Botanicals; Plant allelochemicals; Toxicity; Plant protection; Insect pest management; Mechanism of action; Acetylcholine; Octopamine; GABA
Hormonal evaluation and midcycle detection of intrauterine glycodelin in women treated with levonorgestrel as in emergency contraception
Keywords: مکانیسم عمل; Hormonal emergency contraception; Levonorgestrel; Glycodelin; Mechanism of action
Antimicrobial mechanism of pore-forming protegrin peptides: 100 pores to kill E. coli
Keywords: مکانیسم عمل; Antimicrobial peptides; Mechanism of action; Multiscale model;
Plethora of agents, plethora of targets, plethora of side effects in metastatic renal cell carcinoma
Keywords: مکانیسم عمل; VEGF; Anti-angiogenic drugs; Mechanism of action; Side effects; Renal cell carcinoma
Histone deacetylase inhibitors: A chemical genetics approach to understanding cellular functions
Keywords: مکانیسم عمل; Histone deacetylase; DNA double strand break; HDAC inhibitor; Mechanism of action; Apoptosis; Suberoylanilide hydroxamic acid
Overlapping and distinct mechanisms of action of multiple sclerosis therapies
Keywords: مکانیسم عمل; Multiple sclerosis; Interferon-beta; Glatiramer acetate; Mitoxantrone; Natalizumab; Combination therapy; Mechanism of action
Topoisomerase II inhibition by the bioactivated benzene metabolite hydroquinone involves multiple mechanisms
Keywords: مکانیسم عمل; Benzene; Topoisomerase II; Leukemia; Mechanism of action
Resistencia a la aspirina: prevalencia, mecanismos de acción y asociación con eventos tromboembólicos. Revisión narrativa
Keywords: مکانیسم عمل; Ácido acetilsalicÃlico; Resistencia a fármacos; EpidemiologÃa; Mecanismo de acción; Factores de riesgo; Enfermedad cardiovascular; Revisión; Acetylsalicylic acid; Drug resistance; Epidemiology; Mechanism of action; Risk factors; Cardiovascular disea
Pulmonary Infectious Complications of Tumor Necrosis Factor Blockade
Keywords: مکانیسم عمل; Tumor necrosis factor; Infection; Tuberculosis; Granuloma; Etanercept; Infliximab; Adalimumab; Mechanism of action;
Targeting B cells in immune-mediated inflammatory disease: A comprehensive review of mechanisms of action and identification of biomarkers
Keywords: مکانیسم عمل; Mechanism of action; Rheumatoid arthritis; Systemic lupus erythematosus; Sjögren's syndrome; Biomarker; B cell-targeting drugs; ACPA; anti-citrullinated peptide antibody; ACR; American College of Rheumatology; APRIL; a proliferation-inducing ligand; BCMA
Resistance to aspirin: Prevalence, mechanisms of action and association with thromboembolic events. A narrative review
Keywords: مکانیسم عمل; Acetylsalicylic acid; Drug resistance; Epidemiology; Mechanism of action; Risk factors; Cardiovascular disease; Review; Ácido acetilsalicÃlico; Resistencia a fármacos; EpidemiologÃa; Mecanismo de acción; Factores de riesgo; Enfermedad cardiovascular;
Chemical target and pathway toxicity mechanisms defined in primary human cell systems
Keywords: مکانیسم عمل; Cell-based assay; Endothelial cell; Epithelial cell; Human; Inflammation; Mechanism of action; Microtubule; Mitochondria; Smooth muscle cell; Toxicity pathway
A review of prostaglandin analogs in the management of patients with pulmonary arterial hypertension
Keywords: مکانیسم عمل; Prostacyclin; Treatment; Mechanism of action; Pharmacokinetics; Pulmonary Arterial Hypertension
Mineral Trioxide Aggregate: A Comprehensive Literature Review—Part III: Clinical Applications, Drawbacks, and Mechanism of Action
Keywords: مکانیسم عمل; Apical plug; clinical application; drawbacks; mechanism of action; MTA; perforation; pulp capping; pulpotomy; root-end filling; vital pulp therapy
Inhibition of JAK kinases in patients with rheumatoid arthritis: scientific rationale and clinical outcomes
Keywords: مکانیسم عمل; Janus Kinase (JAK) inhibition; rheumatoid arthritis; clinical effects; mechanism of action
Prediction of drug-related cardiac adverse effects in humans-B: Use of QSAR programs for early detection of drug-induced cardiac toxicities
Keywords: مکانیسم عمل; AERS; BioEpisteme™; Clinical indication; Drug-induced cardiac toxicity; Drug-related adverse effect; In silico; Leadscope FDA Model Applier; MC4PC; Mechanism of action; QSAR; Quantitative structure–activity relationship; SRS; Therapeutic target
Immunosuppression Armamentarium in 2010: Mechanistic and Clinical Considerations
Keywords: مکانیسم عمل; Immunosuppressive treatment; Pediatric transplantation; Solid-organ transplantation; Induction; Maintenance immunosuppression; Mechanism of action; Side effects;
Prediction of drug-related cardiac adverse effects in humans—A: Creation of a database of effects and identification of factors affecting their occurrence
Keywords: مکانیسم عمل; AERS; BioEpisteme™; Clinical indication; Drug-induced cardiac toxicity; Drug-related adverse effect; In silico; Mechanism of action; MedDRA; QSAR; Quantitative structure–activity relationships; SRS; Therapeutic target
Link of the mechanisms of action of glatiramer acetate to its long-term clinical data
Keywords: مکانیسم عمل; Multiple sclerosis; Clinical trials; Interferon-beta; Glatiramer acetate; Long-term outcome; Mechanism of action;
Emergence of Crohn's Disease During Treatment with the Anti-Tumor Necrosis Factor Agent Etanercept for Ankylosing Spondylitis: Possible Mechanisms of Action
Keywords: مکانیسم عمل; Crohn's disease; inflammation; ankylosing spondylitis; tumor necrosis factor-alpha antagonist; biologic therapy; inflammatory bowel disease; mechanism of action
Genomics: Applications in mechanism elucidation
Keywords: مکانیسم عمل; Mechanism of action; Drug discovery; Genomics; Drug target; Small molecule drugs; Molecular interactions; Pharmacogenomics
Mecanismos de acción de los antimicrobianos
Keywords: مکانیسم عمل; Antimicrobianos; Mecanismo de acción; Pared cellular; Membrana citoplásmica; Síntesis proteica; ADN; Vías metabólicasAntimicrobial agents; Mechanism of action; Cell wall; Cytoplasmic membrane; Protein synthesis; DNA; Metabolic pathways
Structure–activity relationships of 4-N-substituted ferroquine analogues: Time to re-evaluate the mechanism of action of ferroquine
Keywords: مکانیسم عمل; Bioorganometallic chemistry; Antimalarial; Ferroquine; Lipophilicity; Mechanism of action
Antimalarial activities of ferroquine conjugates with either glutathione reductase inhibitors or glutathione depletors via a hydrolyzable amide linker
Keywords: مکانیسم عمل; Bioorganometallics; Dual drugs; Hemozoin; Glutathione reductase; Mechanism of action
Peptide microarrays for detailed, high-throughput substrate identification, kinetic characterization, and inhibition studies on protein kinase A
Keywords: مکانیسم عمل; Peptide microarray; PKA; cAMP-dependent protein kinase A; Substrate identification; Enzymology; Michaelis constant; Kinetics; Mechanism of action; IC50; Staurosporin; PKA inhibitor peptide; AMP–PNP
Use and abuse of pyrethrins and synthetic pyrethroids in veterinary medicine
Keywords: مکانیسم عمل; Pyrethrins; Pyrethroids; Mechanism of action; Toxicokinetics; Toxicity; Laboratory and domestic animals
Recommendations on the Use of Botulinum Toxin in the Treatment of Lower Urinary Tract Disorders and Pelvic Floor Dysfunctions: A European Consensus Report
Keywords: مکانیسم عمل; Botulinum toxin; Bladder; Urethra; Children; Prostate; Pelvic floor; Mechanism of action
Identification of structure–activity relationships for adverse effects of pharmaceuticals in humans: Part C: Use of QSAR and an expert system for the estimation of the mechanism of action of drug-induced hepatobiliary and urinary tract toxicities
Keywords: مکانیسم عمل; Adverse drug effects; AERS; Clinical indication; Computational toxicology; Drug-induced kidney toxicity; Drug-induced liver toxicity; In silico; Mechanism of action; Pharmaceutical patent; Post-market reporting; Quantitative structure–activity relationshi
Therapeutic anti-inflammatory mechanism of action of Type I interferons
Keywords: مکانیسم عمل; Type I interferon; Mechanism of action; Anti-inflammatory; Interferon-alpha; Interferon-beta; Interferon-tau
Monoclonal antibodies in the treatment of lymphoid malignancies
Keywords: مکانیسم عمل; Rituximab; Lymphoma patients; Mechanism of action;
Piperidine dispiro-1,2,4-trioxane analogues
Keywords: مکانیسم عمل; Hydrogen peroxide; 1,2,4-Trioxane; Endoperoxide; Antimalarial; Mechanism of action
Antifungal canthin-6-one series accumulate in lipid droplets and affect fatty acid metabolism in Saccharomyces cerevisiae
Keywords: مکانیسم عمل; Canthin-6-one; Saccharomyces cerevisiae; Mechanism of action; Lipid metabolism
Additive interaction between peripheral and central mechanisms involved in the antinociceptive effect of diclofenac in the formalin test in rats
Keywords: مکانیسم عمل; Diclofenac; Antinociception; Formalin test; Mechanism of action; Isobolographic analysis; Additive interaction;