Keywords: قطر متوسط ذرات; Ï; density; Ïapp; apparent density; Ïbulk; bulk density; A200; fumed silica Aerosil® 200 Pharma; C; engineering strain; CNC; cellulose nanocrystals; d50%; median particle diameter; E; porosity of the compact; E0; initial porosity of the powder bed; f;