Keywords: متوسیمین; DNA damage; Elimination reactions; Abasic site; Artificial nuclease; High-throughput screen; AP; Apurinic/Apyrimidinic Site; APE1; Apurinic/Apyrimidinic Endonuclease 1; BER; Base Excision Repair; Fpg; Formamidopyrimidine DNA glycosylase; FITC; Fluorescein
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Inhibitors of nuclease and redox activity of apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1)
Keywords: متوسیمین; Apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1); Apurinic/apyrimidinic (AP) site; Base excision repair (BER); DNA repair; Inhibitors; Methoxyamine; Lucanthone; E3330;
Identification of 3,4-dihydro-2H-thiochromene 1,1-dioxide derivatives with a phenoxyethylamine group as highly potent and selective α1D adrenoceptor antagonists
Keywords: متوسیمین; Phenoxyethylamine derivatives; Selective human α1D adrenoceptor antagonist; 3,4-Dihydro-2H-thiochromene 1,1-dioxide; Ligand-lipophilicity efficiency (LLE); AR; Adrenoceptor; BH3; borane; Boc2O; di-tert-butyl bicarbonate; t-BuXphos; 2-di-tert-butylphosp
Experimental radiotherapyRadiosensitization of non-small-cell lung cancer cells and xenografts by the interactive effects of pemetrexed and methoxyamine
Keywords: متوسیمین; Radiosensitization; Pemetrexed; Methoxyamine; Non-small-cell lung cancer;
Differential effects of methoxyamine on doxorubicin cytotoxicity and genotoxicity in MDA-MB-231 human breast cancer cells
Keywords: متوسیمین; DNA repair; Methoxyamine; Doxorubicin; Base excision repair; Micronuclei; APE1;
Development of a new application of the comet assay to assess levels of O6-methylguanine in genomic DNA (CoMeth)
Keywords: متوسیمین; BER; base excision repair; BG; O6-benzylguanine; Mx; methoxyamine; MMS; methyl methanesulfonate; MMR; mismatch repair; MNU; N-methyl-N-nitrosourea; MPG; N-methylpurine-DNA glycosylase; O6meG; O6-methylguanine; MGMT; O6-methylguanine-DNA methyltransferase;
Development and validation of an LC–MS/MS method for pharmacokinetic study of methoxyamine in phase I clinical trial
Keywords: متوسیمین; Methoxyamine; Temozolomide; LC–MS/MS; DNA base-excision-repair inhibitor; Pharmacokinetic study
Trypanosoma brucei AP endonuclease 1 has a major role in the repair of abasic sites and protection against DNA-damaging agents
Keywords: متوسیمین; AP; apurinic/apyrimidinic; TBAPE1; Trypanosoma brucei AP endonuclease 1; LMAP; Leishmania major AP endonuclease; exoIII; exonuclease III; endoIV; endonuclease IV; OGG1; 8-oxoguanine DNA glycosylase 1; NTH1; endonuclease III; BSD; blasticidin S transferase
Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: Use of APE1 small molecule inhibitors to delineate APE1 functions
Keywords: متوسیمین; APE1; human apurinic (apyrimidinic) endonuclease/redox effector factor; WT-APE1; wild type APE1; C65-APE1; repair competent/redox deficient APE1; 177/226-APE1; repair deficient/redox competent APE1; MX; methoxyamine; BQP; 3-[5-(2,3-dimethoxy-6-methyl-1,4-
Development and validation of an HPLC-UV method for the analysis of methoxyamine using 4-(diethylamino)benzaldehyde as a derivatizing agent
Keywords: متوسیمین; Methoxyamine; 4-(Diethylamino)benzaldehyde; 4-(Diethylamino)benzaldehyde o-methyloxime; Liquid chromatography; Ultraviolet detection; DNA base excision repair;
Quantification of DNA strand breaks and abasic sites by oxime derivatization and accelerator mass spectrometry: Application to γ-radiation and peroxynitrite
Keywords: متوسیمین; DNA damage; Strand breaks; Abasic sites; Accelerator mass spectrometry; Methoxyamine; Oxime derivatization;