Keywords: 2ndAb; secondary antibody; AC; assembly compartment; Act D; actinomycin D; AF; Alexa Fluor; CH; cycloheximide; CMV; cytomegalovirus; CTxB; cholera-toxin B-subunit; E; early; EE; early endosome; EGF; epidermal growth factor; EPERC; early-phase endosomal re
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Keywords: Dendritic cells; Immunogenicity; Glioblastoma; Nano-DOX; Drug delivery; Immunogenic cell death; ATP; adenosine triphosphate; BBB; blood-brain barrier; BCA; bicinchoninic acid; 5-(N-dodecanoyl)aminofluorescein; C11-fluor; DC; dendritic cells; MÏ; macropha
Keywords: CCK-8; cell counting kit-8; DAPI; 4,6-diamidino-2-phenylindole; DMEM; dulbecco's modified Eagle's medium; D-MTJ; decellularized myotendinous junction; ECM; extracellular matrix; EGF; epidermal growth factor; EM; elastic modulus; FBS; fetal bovine seru
Keywords: Radiation; Immunotherapy; Dose; Fractionation; MHC-I; major histocompatibility class I; ICAM-1; intercellular adhesion molecules-1; CEA; carcinoembryonic antigen; CTL; cytotoxic T cells; CTLA-4; cytotoxic T-lymphocyte-associated antigen 4; gp 100; glycopr
Keywords: DMC; dimethylcrocetin; CHD; coronary heart disease; LDL; low density lipoprotein; ROS; reactive oxygen species; PCa; prostate cancer; COX-2; cycloxygenase-2; NF-κB; nuclear factor-κB; RAR; retinoid-like receptors; PPARγ; Peroxisome proliferator-activat
Keywords: APM; antigen processing machinery; BMI; body mass index; CTLs; cytotoxic T-cells; DC; dendritic cells; DCA; dichloroacetate; ERK; extracellular signal-regulated kinases; GTN; glyceryl trinitrate; HAT; histone acetyltransferases; HLA; human leukocyte antig
microRNA 125a Regulates MHC-I Expression on Esophageal Adenocarcinoma Cells, Associated With Suppression of Antitumor Immune Response and Poor Outcomes of Patients
Keywords: miR-125; miR-148; Antitumor Immune Response; Immune Checkpoints; CTL; cytotoxic T lymphocytes; CTLA-4; cytotoxic T lymphocyte associated protein 4; EAC; esophageal adenocarcinoma; gMFI; geometric mean fluorescence intensity; HLA-A/B/C; human leukocyte ant
Dysregulated Response of Follicular Helper T Cells to Hepatitis B Surface Antigen Promotes HBV Persistence in Mice and Associates With Outcomes of Patients
Keywords: Viral Hepatitis; Immune Regulation; Neutralizing Antibody Response; Immunotherapy; ADCC; antibody-dependent cell-mediated cytotoxicity; anti-HBs; antibodies specific for hepatitis B surface antigen; ASC; antibody-secreting cell; CHB; chronic hepatitis B;
Redox control of cancer cell destruction
Keywords: ABC transporters; ATP-binding cassette transporters; ADCC; antibody-dependent cell-mediated cytotoxicity; ADCP; antibody-dependent cancer cell phagocytosis; AML; acute myeloid leukemia; APE1; apurinic/apyrimidinic endonuclease 1; ASK-1; apoptosis signal-r
Major findings and recent advances in virus-like particle (VLP)-based vaccines
Keywords: VLP; virus-like particle; CCMV; cowpea chlorotic mottle virus; HBV; hepatitis B virus; PASP; pathogen associated structural pattern; BCR; B cell receptor; APC; antigen presenting cell; LN; lymph node; SCS; sub capsular sinus; DC; dendritic cell; cDC; conv
Neuronal zinc-α2-glycoprotein is decreased in temporal lobe epilepsy in patients and rats
Keywords: AD; Alzheimer's disease; AED; anti-epileptic drug; BSA; bovine serum albumin; cDNA; complementary deoxyribonucleic acid; Co-IP; co-immunoprecipitation; CSF; cerebrospinal fluid; DAB; 3,3-diaminobenzidine; DAPI; 4,6-diamidino-2-phenylindole; FITC; fluore
Contribution of inhibitory receptor TIGIT to NK cell education
Keywords: NK cells; Education; Licensing; MHC-I; TIGIT; CD155;
Full-length ArticleThe hippocampal transcriptomic signature of stress resilience in mice with microglial fractalkine receptor (CX3CR1) deficiency
Keywords: Microglia; CX3CR1; Stress; Chronic unpredictable stress; Depression; Hippocampus; RNA sequencing; Interferon; Neurogenesis; MHC-I; Igf2;
Importance of major histocompatibility complex of class I (MHC-I) expression for astroglial reactivity and stability of neural circuits in vitro
Keywords: MHC-I; Astrocytic reactivity; Neuron; Synapse; β2m silencing;
The anticancer functions of RIG-I-like receptors, RIG-I and MDA5, and their applications in cancer therapy
Keywords: 5â²PP; 5â²-diphosphate; 5â²ppp; 5â²triphosphorylated; Bcl2; B-cell lymphoma-2; BIRC3; baculoviral IAP repeat-containing 3; CARDs; caspase activation and recruitment domains; CRC; colorectal cancer; CTD; C-terminal domain; CTLs; cytotoxic T lymphocytes
HSPA5 Gene encoding Hsp70 chaperone BiP in the endoplasmic reticulum
Keywords: aa; amino acid; ATF6; activating transcription factor 6; BIK; BCL2-interacting killer; BiP; binding immunoglobulin protein; CD86; cluster of differentiation 86; CHOP; CCAAT-enhancer-binding protein homologous protein; Derlin-1; degradation in ER protein 1
TLR4-HMGB1 signaling pathway affects the inflammatory reaction of autoimmune myositis by regulating MHC-I
Keywords: MHC-I; TLR4-HMGB1 signaling pathway; Autoimmune myositis; Proinflammatory cytokines;
Crystal structure of a polypeptide's C-terminus in complex with the regulatory domain of ER aminopeptidase 1
Keywords: ER; endoplasmic reticulum; ERAP1; endoplasmic reticulum aminopeptidase 1; ERAP1_R; ERAP1 regulatory domain; MHC-I; major histocompatibility complex class I; TAP; transporter associated with antigen processing; rmsd; root mean square deviation/displacement
MHC-I promotes apoptosis of GABAergic interneurons in the spinal dorsal horn and contributes to cancer induced bone pain
Keywords: MHC-I; Cancer induced bone pain; GABAergic interneurons; Disinhibition; CD8+ T cells;
C5b-9 deposits on endomysial capillaries in non-dermatomyositis cases
Keywords: C5b-9; Microvascular unit; Muscle disease; Dermatomyositis; MHC-I;
Human liver-resident CD56bright/CD16neg NK cells are retained within hepatic sinusoids via the engagement of CCR5 and CXCR6 pathways
Keywords: Liver immunology; Homing of hepatic NK cells; Cherokees Chemokine receptors; lr-NK cells; liver resident Natural Killer cells; c-NK cells; conventional Natural Killer cells; perf-NK cells; perfusate Natural Killer cells; iNKRs; inhibitory NK cell receptor
HIV-1 Nef: a master manipulator of the membrane trafficking machinery mediating immune evasion
Keywords: AIDS; HIV-1; Nef; MHC-I; Membrane trafficking; Immune evasion;
Identification of SIV Nef CD8+ T cell epitopes restricted by a MHC class I haplotype associated with lower viral loads in a macaque AIDS model
Keywords: HIV; SIV; CD8+ T cell; MHC-I; Epitope;
Dominant contribution of the proteasome and metalloproteinases to TAP-independent MHC-I peptide repertoire
Keywords: MHC-I; Antigen processing; Proteasome; Transporter associated with peptide processing; Endolysosomal vesicles; TAP-L;
Research ArticleTransfer of MHC-class-I molecules among liver sinusoidal cells facilitates hepatic immune surveillance
Keywords: LSEC; liver sinusoidal endothelial cell; HSC; hepatic stellate cell; LSEC; HSC; Cross-presentation; MHC-I;
Interferon-gamma induced cell death: Regulation and contributions of nitric oxide, cJun N-terminal kinase, reactive oxygen species and peroxynitrite
Keywords: AG; aminoguanidine; BrdU; bromodeoxyuridine; DAF2DA; 4, 5-diaminofluorescein diacetate; DCFDA; 2â², 7â²-dichlorofluorescin diacetate; DHR123; dihydrorhodamine 123; FeTPPS; 5,10,15,20-tetrakis(4-sulfonatophenyl) porphyrinato iron (III), chloride; FITC; f
Retrograde response in axotomized motoneurons: Nitric oxide as a key player in triggering reversion toward a dedifferentiated phenotype
Keywords: AVVs; Adenoviruses; C3; component 3; CAMs; cell adhesion molecules; cGMP; cyclic guanosine monophosphate; CNS; central nervous system; HMNs; hypoglossal motoneurons; HN; hypoglossal nucleus; LVV; lentiviral; mFR; mean firing rate; MHC-I; major histocompat
ReviewEndosomal trafficking of open Major Histocompatibility Class I conformers-Implications for presentation of endocytosed antigens
Keywords: EE; early endosome; eLd; empty Ld; fLd; full Ld; IR; internalization rate; MHC-I; Major Histocompatibility Class I; PM; plasma membrane; LE; late endosome; TEE; tubular early endosomes; TfR; transferrin receptor; VEE; vacuolar early endosomes; Endocytosis
Stability of peptide–HLA-I complexes and tapasin folding facilitation – tools to define immunogenic peptides
Keywords: Tapasin; MHC-I; Peptide; Stability; Vaccine
Mucosal associated invariant T cells and the immune response to infection
Keywords: Mucosal associated invariant T (MAIT) cells; iNKT cells; MR1; MHC-I; Mucosal immunity; Mycobacterium tuberculosis
Real-time, high-throughput measurements of peptide–MHC-I dissociation using a scintillation proximity assay
Keywords: MHC-I; Peptide; Stability; Dissociation; Scintillation proximity assay
ER stress impairs MHC Class I surface expression and increases susceptibility of thyroid cells to NK-mediated cytotoxicity
Keywords: BiP; binding protein (GRP78); ER; endoplasmic reticulum; ERAD; ER associated degradation; GRP94; glucose regulated protein 94; HFE; hereditary hemochromatosis protein; HLA-I; human leukocyte antigen-I; IFN-γ; interferon-γ; IL-2; interleukin-2; MHC-I; ma
Segregation of open Major Histocompatibility Class I conformers at the plasma membrane and during endosomal trafficking reveals conformation-based sorting in the endosomal system
Keywords: β2m; β2-microglobulin; BFA; brefeldin A; CTxB; cholera-toxin B subunit; EE; early endosome; EEA1; early endosomal antigen 1; eLd; empty Ld; fLd; full Ld; GM1; ganglioside M1; HC; heavy chain; IR; internalization rate; LBPA; lysobisphosphatidic acid; MHC
DC-expressed MHC class I single-chain trimer-based vaccines prime cytotoxic T lymphocytes against exogenous but not endogenous antigens
Keywords: Single-chain trimer; MHC-I; Melanoma; Dendritic cell; Gene Gun; Tyrosinase-related protein; Tumor antigen; B16
Proteasome inhibitors: Dozens of molecules and still counting
Keywords: Proteasome; Ubiquitin; Inhibitors; Proteasome inhibitors; AAA; ATPases Associated with various cellular Activities; PI; proteasome inhibitor; MM; Multiple Myeloma; UPS; Ubiquitin-proteasome system; MHC-I; Major Histocompatibility Complex I; CT-L, T-L, C
Role of immunolglobulin-like transcript family receptors and their ligands in suppressor T-cell–induced dendritic cell tolerization
Keywords: ILT family; DC tolerization; Suppressor T cells; MHC-I; CD1d
Simultaneous assessment of CD4 and MHC-I downregulation by Nef primary isolates in the context of infection
Keywords: HIV-1; Nef; MHC-I; CD4
Classical and non-classical Major Histocompatibility Complex class I gene expression in in vitro derived bovine embryos
Keywords: Oocyte; Preimplantation Embryo; mRNA; Development; MHC-I
Ecto-F1-ATPase and MHC-class I close association on cell membranes
Keywords: ApoA1; apolipoprotein A-I; β2m; beta-2-microglobulin; α-F1, β-F1; alpha and beta subunits of F1 domain of ATP synthase; EBV-B; Epstein-Barr virus-immortalized B cell line; TAP; transporter associated with antigen processing; MHC-I; MHC-class I antige
Molecular modelling of co-receptor CD8αα and its complex with MHC class I and T-cell receptor in sea bream (Sparus aurata)
Keywords: Sparus aurata; Molecular modelling; Protein structure; CD8; T-cell receptor; MHC-I
Progressive myopathy with up-regulation of MHC-I associated with statin therapy
Keywords: Myopathy; Statin; ER stress; MHC-I;
In vitro atrazine exposure affects the phenotypic and functional maturation of dendritic cells
Keywords: Atrazine; Pesticide immunotoxicity; Dendritic cells; Maturation; MHC-I;
Immunological validation of the EpitOptimizer program for streamlined design of heteroclitic epitopes
Keywords: MHC-I; major histocompatibility complex I; TYRP1; tyrosinase-related protein 1; PSMA; human prostate-specific membrane antigen; PSMAee; epitope enriched PSMA; APCs; antigen presenting cells; T Cells; Antigens/peptides/epitopes; Tumor immunity; Vaccination
CD4 and MHC-I downregulation are conserved in primary HIV-1 Nef alleles from brain and lymphoid tissues, but Pak2 activation is highly variable
Keywords: Human Immunodeficiency Virus type 1 (HIV-1); Nef; Brain; Lymph node; CD4; MHC-I; Pak2
ICAM-1 inhibits the homocluster formation of MHC-I in colon carcinoma cells
Keywords: ICAM-1; MHC-I; Receptor clustering; RNA interference; FRET; Flow cytometry; Confocal microscopy; Membrane protein association; Colon carcinoma
T-cell epitope repertoire as predicted from human and viral genomes
Keywords: MHC-I; Peptide; Repertoire; Self; Immunome;
The three-dimensional structure of β2 microglobulin: Results from X-ray crystallography
Keywords: r.m.s.; root mean square; β2m; β2 microglobulin; MHC-I; human class I Major Histocompatibility Complex; DRA; dialysis related amyloidosis; H31Y-β2m; the His31 â Tyr β2m mutant; β2 microglobulin; Class I major histocompatibility complex; Dialysis
Ligand recognition by antigen-presenting cell C-type lectin receptors
Keywords: APC; antigen-presenting cell; BDCA; blood DC antigen; CLR; C-type lectin receptor; CRD; carbohydrate recognition domain; DC; dendritic cell; FN-II; fibronectin type II; ICAM; intercellular adhesion molecule; ITAM; immunotyrosine activatory motif; MÃ; mac
The poxviral scrapin MV-LAP requires a myxoma viral infection context to efficiently downregulate MHC-I molecules
Keywords: Poxviruses; Myxomatosis; Myxoma virus; MHC-I; Regulation; Cell surface receptors; Virulence; Viral proteins; Ubiquitin;