Keywords: AFM; absolute fat mass; ALM; arm lean mass; AUC; area under the curve; β2M; beta-2-microglobulin; BCAA; branch chained amino acids; CCTS; Center for Clinical and Translational Science; CD11b; cluster of differentiation 11b; CD68; cluster of differentiati
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Keywords: CA/CPR; cardiac arrest/cardiopulmonary resuscitation; OGD; oxygen-glucose deprivation; aCSF; artificial cerebrospinal fluid; rtPCR; real-time polymerase chain reaction; MHC II; major histocompatibility complex II; TNF-α; tumor necrosis factor alpha; IL-1
Keywords: 2-DG; 2-deoxy glucose; Akt; protein kinase B; ARDS; acute respiratory distress syndrome; Arg; arginase; BALF; broncho-alveolar lavage fluid; BCG; Bacillus Calmette-Guérin; CD; cluster of differentiation; cGAS; cyclic GMP-AMP synthase; COX-2; cyclooxyge
Keywords: Biological toxins; Ricin; Botulinum neurotoxin; Staphylococcal enterotoxin; Saxitoxin; Standardization; Proficiency testing; AOAC; AOAC International; BoNT; Botulinum neurotoxin; CRM; Certified reference material; CWC; Chemical Weapons Convention; EFSA; E
Keywords: TPP; therapeutic protein product; ADA; anti-drug antibody; mAb; monoclonal antibody; RA; rheumatoid arthritis; MS; multiple sclerosis; IBD; inflammatory bowel disease; NAb; neutralizing ADA; non-NAb; non-neutralizing ADA; PK; pharmacokinetics; PRCA; pure
Keywords: 11β-HSD1; 11β-hydroxysteroid dehydrogenase type 1; BDNF; brain-derived neurotrophic factor; CCI; controlled cortical impact; CD11b; complement receptor 3; CORT; corticosterone; ERK; extracellular signal-regulated protein kinase; GC; glucocorticoid; GLT1
Keywords: Breast cancer; Immune system; Biomarkers; Immunotherapies; Immune checkpoint blockade; Tumor vaccines; ADCC; antibody dependent cellular cytotoxicity; BiTES; bispecific single chain monoclonal antibodies; CAR; T cells engineered to express artificial chim
Keywords: Vaccination; Neonate; Infants; Children; B cells; T cells; Antigen presenting cells; Dendritic cells; immunologic memory; pediatric vaccines; Streptococcus pneumoniae; Haemophilus influenzae; B-cell receptor; MHC II; CD4 T-cells; cytokines; T-cell recepto
Inhibitive Effect of Resveratrol on the Inflammation in Cultured Astrocytes and Microglia Induced by Aβ1-42
Keywords: AD; Alzheimer's disease; Aβ; beta-amyloid; APC; antigen-presenting cell; BACE1; β-site APP cleaving enzyme 1; BBB; blood-brain barrier; CCK; cell-counting kit; CD40; cluster of differentiation 40; CNS; central nervous system; DAPI; 4â²,6-diamidino-
NOD and NOR mice exhibit comparable development of lacrimal gland secretory dysfunction but NOD mice have more severe autoimmune dacryoadenitis
Keywords: CTSS; Cathepsin S; IFN- γ; Interferon-γ; LG; lacrimal gland; LGAC; lacrimal gland acinar cell; MEC; myoepithelial cell; MHC II; major histocompatibility complex II; NOD; Non-Obese Diabetic; NOR; Non-Obese Diabetes Resistant; SG; salivary gland; SMA; α-
Role of thymic B cells in the development of thymus-derived regulatory T cell in vitro
Keywords: Thymic B cells; IMQ; LPS; nTregs; Costimulatory molecules; MHC II;
MiR-212-3p inhibits LPS-induced inflammatory response through targeting HMGB1 in murine macrophages
Keywords: LPS; lipopolysaccharide; TLRs; Toll-like receptors; HMGB1; high mobility group box 1; miRNAs; microRNAs; mRNAs; messenger RNAs; siRNA; small interfering RNA; UTR; untranslated region; Mut; mutated; TNF-α; tumor necrosis factor-alpha; IL-6; interleukin-6;
MHC IIâ, but not MHC II+, hepatic Stellate cells contribute to liver fibrosis of mice in infection with Schistosoma japonicum
Keywords: HSCs; hepatic stellate cells; FCM; flow cytometry; MHC II; major histocompatibility complex class II; α-SMA; alpha-smooth muscle actin; Col1α1; Collagen1α1; Timp1; tissue inhibitor of metalloproteinase-1; PD-L1; programmed death ligand 1; LRAT; lecithi
Immunolocalization of immune cells and cell cycle proteins in the bulbus arteriosus of Atlantic salmon (Salmo salar L.)
Keywords: Atlantic salmon; Bulbus arteriosus; Caspase; CD3; HIF1α; Immunohistochemistry; MHC II; TNFα
The arginine methyltransferase PRMT5 regulates CIITA-dependent MHC II transcription
Keywords: Transcriptional regulation; Epigenetics; PRMT5; CIITA; MHC II; Macrophage
Allergic lung inflammation promotes atherosclerosis in apolipoprotein E-deficient mice
Keywords: ALI; allergic lung inflammation; SBP; systolic blood pressure; DBP; diastolic blood pressure; Apoe; apolipoprotein E; SMC; smooth muscle cell; IMT; intima-media thickness; OR; odds ratio; CI; confidential interval; OVA; ovalbumin; MHC II; major histocompa
Single nucleotide polymorphisms in major histocompatibility class II haplotypes are associated with potential resistance to inflammatory bowel disease in German shepherd dogs
Keywords: Canine; GSD; Inflammatory bowel disease; MHC II; DLA II;
MHC II-β chain gene expression studies define the regional organization of the thymus in the developing bony fish Dicentrarchus labrax (L.)
Keywords: MHC II; Dendritic cells; Thymic epithelial cells; Thymus; TeleostAPCs, antigen presenting cells; BSA, bovine serum albumin; CK, cytokeratin; CMB, cortico-medullary border; Ct, threshold cycle; cTECs, cortical thymic epithelial cells; DCs, dendritic cells;
Minocycline protects the immature white matter against hyperoxia
Keywords: CC; corpus callosum; EC; external capsule; FA; fractional anisotropy; IL; interleukin; IFN; interferon; iNOS; inducible NO synthase; MHC II; major histocompatibility class II; MBP; myelin basic protein; MRI; magnet resonance imaging; NGS; normal goat seru
Cross-species association of quail invariant chain with chicken and mouse MHC II molecules
Keywords: Quail; Invariant chain; MHC II; Cross-species; Similarity analysis
Tollip-induced down-regulation of MARCH1
Keywords: Tollip; MARCH1; MHC II; TLR3; Antigen presentationTLR, toll-like receptor; PAMPs, pathogen-associated molecular patterns; TIR, Toll/IL-1 receptor; APCs, antigen presenting cells; SOCS1, suppressor of cytokine signaling 1; Tollip, Toll-interacting protein;
Apicidin and Docetaxel Combination Treatment Drives CTCFL Expression and HMGB1 Release Acting as Potential Antitumor Immune Response Inducers in Metastatic Breast Cancer Cells
Keywords: CTCFL; CTCF-like protein; HDACi; histone deacetylase inhibitors; CT; cancer testis; CRT; calreticulin; HMGB1; high-mobility group box 1 protein; MHC I; major histocompatibility complex class I; DCs; dendritic cells; MTS; 3-(4,5-dimethylthiazol-2-yl)-5-(3-
Proteolytic and non-proteolytic roles of ubiquitin and the ubiquitin proteasome system in transcriptional regulation
Keywords: 19S ATPases; Ubiquitin; Proteasome; CIITA; MHC II
Small molecule modulators of MHC class II antigen presentation: Mechanistic insights and implications for therapeutic application
Keywords: MHC; major histocompatibility complex; MHC II; MHC class II molecules; APC; antigen presenting cells; ER; endoplasmic reticulum; Ii; invariant chain; MIIC; MHC class II-containing compartment; HLA; human leukocyte antigen; DM; HLA-DM; DR; HLA-DR; DR1; DRA
Synthesis and immunomodulatory activity of [60]fullerene–tuftsin conjugates
Keywords: Fullerene C60; Tuftsin; Peritoneal macrophages; Phagocytosis; Chemotaxis; MHC II
Androgens suppress antigen-specific T cell responses and IFN-γ production during intracranial LCMV infection
Keywords: Viral infection; Neuroimmunology; Cytokines; T cells; MHC II; Androgens;
Activin A down-regulates the phagocytosis of lipopolysaccharide-activated mouse peritoneal macrophages in vitro and in vivo
Keywords: Activin; Lipopolysaccharide; Macrophage; Phagocytosis; MHC II; CD14
BiodMHC: an online server for the prediction of MHC class II-peptide binding affinity
Keywords: MHC II; MHC-peptide binding predictions; web server
HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells
Keywords: CIITA; HDAC2-mediated deacetylation; Transcriptional regulation; Protein degradation; RFX5; MHC II; Collagen type I; Smooth muscle cell; Macrophage; Atherogenesis
PPARγ enhances IFNγ-mediated transcription and rescues the TGFβ antagonism by stimulating CIITA in vascular smooth muscle cells
Keywords: PPARγ; IFN-γ; TGF-β; CIITA; MHC II; Collagen type I; Transcriptional regulation; Protein degradation; Atherogenesis
Invariant chain+ N2a neuroblastoma cells stably expressing the class II MHC transactivator CIITA fail to stimulate anti-tumor immunity
Keywords: Invariant chain; CIITA; Neuroblastoma; N2a; Tumor vaccine; MHC II
Microglia repetitively isolated from in vitro mixed glial cultures retain their initial phenotype
Keywords: Microglia; Lipopolysaccharide (LPS); Phagocytic; TNFα; IL-6; CD68; CD11b; CD45; MHC II;
ZXDC, a novel zinc finger protein that binds CIITA and activates MHC gene transcription
Keywords: MHC II; Transcriptional regulation; Zinc finger; Molecular biology
MHC class II expression by follicular keratinocytes in canine demodicosis—An immunohistochemical study
Keywords: Demodicosis; MHC II; Canine; Immunohistochemistry; Keratinocyte; Skin
Microglia serve as a neuroimmune substrate for stress-induced potentiation of CNS pro-inflammatory cytokine responses
Keywords: Stress; CNS; Pro-inflammatory cytokines; Interleukin 1-β; Microglia; MHC II; CD200; Sensitization; Priming
Immune cell involvement in dorsal root ganglia and spinal cord after chronic constriction or transection of the rat sciatic nerve
Keywords: Neuroinflammation; Macrophage; Microglia; Astrocyte; OX-42 (CD11b); MHC I; MHC II; ED1 (CD68); CD8+ T-cells; CD4+ macrophages
mRNA up-regulation of MHC II and pivotal pro-inflammatory genes in normal brain aging
Keywords: Aging; Macrophage; Microglia; Immune; Pro-inflammatory; MHC II; Hippocampus
Rapid isolation of highly enriched and quiescent microglia from adult rat hippocampus: Immunophenotypic and functional characteristics
Keywords: Microglia; Isolation; Density gradient; Percoll; Immunophenotype; In situ; CD11b; MHC II
Uneven distribution of MHC class II epitopes within the influenza virus
Keywords: T cells; MHC II; Influenza; Vaccination
BCG vaccination of guinea pigs modulates Mycobacterium tuberculosis-induced CCL5 (RANTES) production in vitro and in vivo
Keywords: Macrophage; IFNγ; Pleurisy; MHC II; CCL5; Mycobacterium
Monocyte-derived dendritic cells
Keywords: DC; dendritic cell; MHC II; MHC class II; Dendritic cells; Monocytes; DC precursors;
West Nile premembrane-envelope genetic vaccine encoded as a chimera containing the transmembrane and cytoplasmic domains of a lysosome-associated membrane protein: increased cellular concentration of the transgene product, targeting to the MHC II compartm
Keywords: preM-E; premembrane-envelope; LAMP; lysosome-associated membrane protein; MHC; major histocompatibility complex; MIICs; MHC II-containing compartments; H-2M; peptide editor; WN; West Nile virus; JE; Japanese encephalitis virus; pVax-WN; pVAX WN preM-E DNA
Prostaglandin E2 modulation of gene expression in an Atlantic salmon (Salmo salar) macrophage-like cell line (SHK-1)
Keywords: Real-time PCR; Gene expression; Cytokines; IL-1β; TNFα; MHC I; MHC II; TGFβ; COX-2; Inflammation; Macrophage-like cell line; Prostaglandin E2; Atlantic salmon;
Role of double-stranded RNA and Npro of classical swine fever virus in the activation of monocyte-derived dendritic cells
Keywords: Pestivirus; Classical swine fever virus; Npro; Double-stranded RNA; Dendritic cell; Interferon-α/β; CD80/86; MHC II; Innate immunity;
Functional identification of kinases essential for T-cell activation through a genetic suppression screen
Keywords: GSE; genetic suppressor element; STE; homologs to yeast sterile7, sterile 11, and sterile 20 kinases; CAMK; calcium/calmodulin-dependent-like protein kinases; AGC; containing PAK, PKG, and PKC kinase families; CMGC; containing CDK, MAPK, GSK3, and CLK kin
The role of inflammation in Alzheimer's disease
Keywords: αBTx; α-bungarotoxin; Aβ; beta-amyloid protein; ACh; acetylcholine; AChBP; acetylcholine-binding protein; AChR; nicotinic acetylcholine receptor; AD; Alzheimer's disease; AICD; amyloid precursor protein intracellular domain; AP; amyloid P; APP; amyloid