Keywords: ثبات میکروسکوپی; Matrix metalloproteinase 13; Structure-property relationship; Structure-activity relationship; Microsomal stability; Solubility; Permeability; In vitro and in vivo pharmacokinetics;
مقالات ISI ثبات میکروسکوپی (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: ثبات میکروسکوپی; Trypanosoma brucei; Triazine; Phenotypic screening; Microsomal stability; Cidal efficacy;
Keywords: ثبات میکروسکوپی; Trypanosoma brucei; Dimer; Microsomal stability; Phenotypic screening;
Keywords: ثبات میکروسکوپی; pharmacokinetics; ADME; transporters; CYP enzymes; P-glycoprotein; microsomal stability
Keywords: ثبات میکروسکوپی; Mitochondria; Cytoprotection; Lipid peroxidation; Reactive oxygen species; Microsomal stability
Spiro-1-benzofuranpiperidinylalkanoic acids as a novel and selective sphingosine S1P5 receptor agonist chemotype
Keywords: ثبات میکروسکوپی; S1P5 receptor agonists; Subtype selectivity; Spirocyclic scaffold; Molecular modelling; Homology model; Oral bioavailability; Turbidimetric aqueous solubility; Microsomal stability; Membrane permeation;
Development and validation of a highly sensitive LC–MS/MS-ESI method for quantification of IIIM-019—A novel nitroimidazole derivative with promising action against Tuberculosis: Application to drug development
Keywords: ثبات میکروسکوپی; IIIM-019; Nitroimidazole; LC–MS/MS; Pharmacokinetic study; Microsomal stability
Discovery of novel N,N-3-phenyl-3-benzylaminopropionanilides as potent inhibitors of cholesteryl ester transfer protein in vivo
Keywords: ثبات میکروسکوپی; CETP inhibitor; N,N-3-Phenyl-3-benzylaminopropionanilide derivatives; Microsomal stability; Dose-dependent
II. Discovery of a novel series of CXCR3 antagonists with a beta amino acid core
Keywords: ثبات میکروسکوپی; QFOOZQUUYROMBF-QFIPXVFZSA-N; LJWSTVOVBMILMB-VWLOTQADSA-N; GZIJLFNNAVWXNH-QFIPXVFZSA-N; Chemokine receptor; CXCR3 antagonist; Inflammatory disease; Microsomal stability; Caco-2 permeability;
I. Discovery of a novel series of CXCR3 antagonists. Multiparametric optimization of N,N-disubstituted benzylamines
Keywords: ثبات میکروسکوپی; FDASGQXFJFJJMH-MYIHVTGJSA-N; CQSXEWQTJJBVIV-YBXDKENTSA-N; Chemokine receptor; CXCR3 antagonist; Inflammatory disease; Microsomal stability; Caco-2 permeability;
Optimization of pyrimidinol antioxidants as mitochondrial protective agents: ATP production and metabolic stability
Keywords: ثبات میکروسکوپی; Mitochondria; Cytoprotection; Lipid peroxidation; Reactive oxygen species; Microsomal stability;
Synthesis and SAR of 4-aminocyclopentapyrrolidines as orally active N-type calcium channel inhibitors for inflammatory and neuropathic pain
Keywords: ثبات میکروسکوپی; N-type calcium channels; SAR; Enantiomeric synthesis; Microsomal stability; Analgesia;
Arylpiperazines as fatty acid transport protein 1 (FATP1) inhibitors with improved potency and pharmacokinetic properties
Keywords: ثبات میکروسکوپی; Fatty acid transport protein; High-throughput screening; Microsomal stability; Arylpiperazine;
1,1-Difluoroethyl-substituted triazolothienopyrimidines as inhibitors of a human urea transport protein (UT-B): New analogs and binding model
Keywords: ثبات میکروسکوپی; Urea transport protein; Triazolothienopyrimidine; Microsomal stability; Molecular docking
Optimization of tricyclic Nec-3 necroptosis inhibitors for in vitro liver microsomal stability
Keywords: ثبات میکروسکوپی; Nec-3; Necroptosis; Inhibitors; Structure-activity relationship; Microsomal stability;
1,5-Substituted nipecotic amides: Selective PDE8 inhibitors displaying diastereomer-dependent microsomal stability
Keywords: ثبات میکروسکوپی; Phosphodiesterase 8; Pancreas; Diabetes; Microsomal stability
N-Heteroaryl glycinamides and glycinamines as potent NPY5 antagonists
Keywords: ثبات میکروسکوپی; NPY5; N-Aryl glycinamide; Microsomal stability; Brain penetration;
A general HPLC–UV method for the quantitative determination of curcumin analogues containing the 1,5-diaryl-3-oxo-1,4-pentadienyl pharmacophore in rat biomatrices
Keywords: ثبات میکروسکوپی; Curcumin analogues; HPLC; Microsomal stability; Piperidones; Rat biomatrices; Validation
Discovery and optimization of piperidyl benzamide derivatives as a novel class of 11β-HSD1 inhibitors
Keywords: ثبات میکروسکوپی; 11β-HSD1; Type II diabetes; Insulin sensitivity; Cyclohexyl benzamide; Piperidyl benzamide; PXR; Microsomal stability; Hepatocyte stability
Structure–activity relationship study of EphB3 receptor tyrosine kinase inhibitors
Keywords: ثبات میکروسکوپی; Structure–activity relationship; EphB3; Kinase; Inhibitor; Microsomal stability
Imidazolylpyrimidine based CXCR2 chemokine receptor antagonists
Keywords: ثبات میکروسکوپی; Chemokine; CXCR2; Pyrimidine; Microsomal stability; Oral bioavailability