
Regioselective synthesis of 3,4-diaryl-5-unsubstituted isoxazoles, analogues of natural cytostatic combretastatin A4
Keywords: 3,4-Diarylisoxazoles; Nitrostilbenes; Microtubule destabilization; Sea urchin embryo; CA4; Combretastatin A-4; SAR; Structure-activity relationship; GBKHOHLOCMEYNJ-UHFFFAOYSA-M; FQHUHJSBBHMRCS-UHFFFAOYSA-N; JLRWQGZARABRGN-UHFFFAOYSA-N; BUUYQSHIWZQFEM-UHFF