Keywords: شیار کوچک; Ferulago macrocarpa (Fenzl) Boiss.; Grandivittin; DNA binding; Minor groove; Molecular docking
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Design, synthesis, nuclear localization, and biological activity of a fluorescent duocarmycin analog, HxTfA
Keywords: شیار کوچک; Duocarmycins; Tafuramycin A; Cytotoxic; Antimalarial; Vaccine; Minor groove; Adenine-N3; Alkylating agent;
Dimerization and DNA recognition rules of mithramycin and its analogues
Keywords: شیار کوچک; DNA binding; Natural product; Minor groove; Anticancer agent; Metal ion coordination
Effect of temperature on the structure and hydration layer of TATA-box DNA: A molecular dynamics simulation study
Keywords: شیار کوچک; Molecular dynamics simulations; DNA; TATA-box; Major groove; Minor groove
AzaHx, a novel fluorescent, DNA minor groove and G·C recognition element: Synthesis and DNA binding properties of a p-anisyl-4-aza-benzimidazole-pyrrole-imidazole (azaHx-PI) polyamide
Keywords: شیار کوچک; AzaHx; Hx-amides; DNA; Sequence recognition; Minor groove; Distamycin; Polyamides; Hoechst 33258
DNA as a target for antimicrobials
Keywords: شیار کوچک; DNA; Antimicrobial; Antibiotic; Intercalation; Minor groove; Major groove;
Design, synthesis, and DNA binding characteristics of a group of orthogonally positioned diamino, N-formamido, pyrrole- and imidazole-containing polyamides
Keywords: شیار کوچک; Polyamides; Diamino; Minor groove; Sequence specificity; Core rules;
Hx-amides: DNA sequence recognition by the fluorescent Hx (p-anisylbenzimidazole)•pyrrole and Hx•imidazole pairings
Keywords: شیار کوچک; Hx-amides; DNA; Sequence recognition; Minor groove; Distamycin; Hoechst 33258
Zinc(II) complexes of Pro-Gly and Pro-Leu dipeptides: Synthesis, characterization, in vitro DNA binding and cleavage studies
Keywords: شیار کوچک; Dipeptide complexes; Hydrolytic cleavage; Minor groove; T4 DNA ligase; Molecular docking
Programmable DNA-binding small molecules
Keywords: شیار کوچک; Polyamide; Transcription; Minor groove; DNA binding
Determination of the drug–DNA binding modes using fluorescence-based assays
Keywords: شیار کوچک; Nucleic acid; Drug–DNA interaction; Fluorescence; Intercalation; Minor groove; Tricyclic antidepressants; Antiprotozoal drug and antibiotic; Food colorants
Stabilization of DNA duplex by 2-substituted adenine as a minor groove modifier
Keywords: شیار کوچک; DNA; Minor groove; Modified nucleoside; π-Stacking; Ethynyl linker
Synthesis and biophysical evaluation of 3′-Me-α-l-LNA – Substitution in the minor groove of α-l-LNA duplexes
Keywords: شیار کوچک; α-l-LNA; 3′-Me-α-l-LNA; Minor groove; Thermal stability
Design, synthesis and DNA binding properties of orthogonally positioned diamino containing polyamide f-IPI
Keywords: شیار کوچک; Polyamides; Minor groove; Gene regulation; DNA binding; ACGCGT
Complexes of mismatched and complementary DNA with minor groove binders. Structures at nucleotide resolution via an improved hydroxyl radical cleavage methodology
Keywords: شیار کوچک; DNA; Minor groove; Lesion; DNA repair; Hydroxyl radical; Fluorescence; Mismatch;
A novel achiral seco-cyclopropylpyrido[e]indolone (CPyI) analog of CC-1065 and the duocarmycins: Synthesis, DNA interactions, in vivo anticancer and anti-parasitic evaluation
Keywords: شیار کوچک; Duocarmycins; Centanamycin; Achiral; Minor groove; DNA; Alkylation; Adenine-N3; Anticancer; Anti-parasite; Antimalaria; Antitrypanosoma; Antileishmania;
Design, synthesis and biological evaluation of a novel series of anthrapyrazoles linked with netropsin-like oligopyrrole carboxamides as anticancer agents
Keywords: شیار کوچک; Netropsin; DNA; Minor groove; Intercalator; Anthrapyrazole; Anticancer; Topoisomerase I; Topoisomerase II; Cytotoxic
Triple recognition of B-DNA
Keywords: شیار کوچک; Neomycin; DNA recognition; Intercalation; Minor groove; Major groove;
DNA minor groove binders: Back in the groove
Keywords: شیار کوچک; Minor groove; Trabectidin; Irofulven; Brostallicin; Alkylators
2-Aminopurine/cytosine base pair containing oligonucleotides: Fluorescence spectroscopy studies on DNA–polyamide binding
Keywords: شیار کوچک; Fluorescence; Polyamide; Minor groove; 2-Aminopurine; Gene regulation
DNA A-tracts bending: Polarization effects on electrostatic interactions across their minor groove
Keywords: شیار کوچک; DNA electrostatics; Minor groove; Polarization interactions; DNA bending
Molecular modelling methods for prediction of sequence-selectivity in DNA recognition
Keywords: شیار کوچک; DNA; Molecular modelling; Minor groove; Hoechst 33258; Sequence selectivity
Property of the M-DNA probed by a minor groove binding dye 4â²,6-diamidino-2-phenylindole
Keywords: شیار کوچک; DNA; M-DNA; Minor groove; 4â²,6-Diamidino-2-phenylindole; Polarized spectroscopy; Binding mode;
Two closely related nickel complexes have different effects on DNA damage and cell viability
Keywords: شیار کوچک; Nickel complex; DNA damage; Comet assay; Cytotoxic; Genotoxic; Intercalation; Minor groove; Carcinogenicity
Synthesis and DNA binding properties of pyrrole amino acid-containing peptides
Keywords: شیار کوچک; Pyrrole amino acid; DNA binding; Minor groove; Distamycin analogues;