کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2148277 | 1089549 | 2011 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Complexes of mismatched and complementary DNA with minor groove binders. Structures at nucleotide resolution via an improved hydroxyl radical cleavage methodology
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Complexes of mismatched and complementary DNA with minor groove binders. Structures at nucleotide resolution via an improved hydroxyl radical cleavage methodology Complexes of mismatched and complementary DNA with minor groove binders. Structures at nucleotide resolution via an improved hydroxyl radical cleavage methodology](/preview/png/2148277.png)
چکیده انگلیسی
⺠An improved hydroxyl radical cleavage protocol has been developed. ⺠The structures of AC and CC mismatches have been investigated by the new protocol. ⺠The structures of minor groove binder-DNA complexes have also been investigated. ⺠The cleavage results are consistent with predictions from crystal structures. ⺠The presence of an AC or CC mismatch has been found to alter minor groove binding.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mutation Research/Genetic Toxicology and Environmental Mutagenesis - Volume 726, Issue 1, 27 November 2011, Pages 47-53
Journal: Mutation Research/Genetic Toxicology and Environmental Mutagenesis - Volume 726, Issue 1, 27 November 2011, Pages 47-53
نویسندگان
Dobroslawa Bialonska, Kenneth Song, Philip H. Bolton,