Keywords: مصرف اکسیژن میتوکندری; 8-oxodG; 8-oxo-7,8-dihydro-2â²deoxyguanosine; BER; base excision repair; DR; dietary restriction; %FRL; percentage free radical leak; IGF; insulin-like growth factor; IIS; insulin/insulin-like growth factor signaling; MetR; methionine restriction; mtDNA;