دانلود مقالات ISI درباره MM، میلوم چندگانه + ترجمه فارسی

تجزیه و تحلیل هزینه-اثربخشی هپارین با وزن مولکولی پایین در مقایسه با آسپیرین ترومبوفیلاکسیس در بیماران تازه تشخیص داده شده با مولتیپل میلوما

Cost-effectiveness analysis of low-molecular-weight heparin versus aspirin thromboprophylaxis in patients newly diagnosed with multiple myeloma

Keywords: MM، میلوم چندگانه; TE, Venous thromboembolic events; MM, multiple myeloma; IMiDs, Immunomodulatory drugs; LMWH, low-molecular weight heparin; QALYs, quality-adjusted life years; PE, pulmonary embolism; DVT, deep venous thrombosis; AT, arterial thrombosis; AMI, acute myocard

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

مهار فعالیت پروتئازوم استاندارد مثل تایپوگرافی، سمیت سلولی ناشی از دوکسوروبیسین را در کاردیومیوسیتهای اولیه تشدید می کند

Inhibition of chymotryptic-like standard proteasome activity exacerbates doxorubicin-induced cytotoxicity in primary cardiomyocytes

Keywords: MM، میلوم چندگانه; DOX, doxorubicin; MM, multiple myeloma; UPS, ubiquitin-proteasome system; ANT, anthracyclin; ROS, reactive oxygen species; SP, standard proteasome; IP, immunoproteasome; PI, proteasome inhibitor; CM, cardiomyocyte; ABP, activity-based probeProteasome; Sub

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

بیمار، پزشک و عوامل زمینه ای در تصمیم گیری درمانی در افراد مسن که به تازگی تشخیص داده شده اند با میلوما علامت دار

Patient, physician and contextual factors are influential in the treatment decision making of older adults newly diagnosed with symptomatic myeloma

Keywords: MM، میلوم چندگانه; TDM, treatment decision making; MM, multiple myeloma; QOL, quality of life; HSCT, hematopoietic stem cell transplantation; RCT, randomized controlled trials; HDT, high dose therapyMultiple myeloma; Older adults; Treatment decision making; Decision making

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

The evaluation of NT-proCNP, C-reactive protein and serum amyloid A protein concentration in patients with multiple myeloma undergoing stem cell transplantation

Keywords: MM، میلوم چندگانه; MM, multiple myeloma; NT-proCNP, amino-terminal pro C-type natriuretic peptide; ASCT, autologous stem cell transplantation; CRP, C-reactive protein; SAA, serum amyloid A protein; TNF-β, tumor necrosis factor-β; ANP, atrial natriuretic peptide; BNP, brain

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Does AL amyloidosis have a unique genomic profile? Gene expression profiling meta-analysis and literature overview

Keywords: MM، میلوم چندگانه; ALA, immunoglobulin light chain amyloidosis; AL, amyloidosis; MM, multiple myeloma; MGUS, monoclonal gammopathy of undetermined significance; PC, plasma cell; SAM, Significant Analysis of Microarrays; PAM, prediction analysis of microarrays; MDS, multidim

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Comparison of chest-CT findings of Influenza virus-associated pneumonia in immunocompetent vs. immunocompromised patients

Keywords: MM، میلوم چندگانه; AML, acute myelogenous leukemia; MM, multiple myeloma; MDS, myelodysplastic syndrome; NHL, non-Hodgkin lymphoma; CLL, chronic lymphocytic leukemia; ALL, acute lymphocytic leukemia; PRCA, pure red cell aplasia; CML, chronic myelogenous leukemia; PCNSL, pri

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

The proteasome inhibitor bortezomib induces testicular toxicity by upregulation of oxidative stress, AMP-activated protein kinase (AMPK) activation and deregulation of germ cell development in adult murine testis

Keywords: MM، میلوم چندگانه; BTZ, bortezomib; UPS, ubiquitin and proteasome dependent proteolytic system; MM, multiple myeloma; i.p., intraperitoneally; T, testosterone; LH, luteinizing hormone; FSH, follicle-stimulating hormone; SCs, radioimmunoassay (RIA) Sertoli cells; GCs, germ c

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Targeting the Pro-Survival Protein MET with Tivantinib (ARQ 197) Inhibits Growth of Multiple Myeloma Cells 12

Keywords: MM، میلوم چندگانه; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; GSK-3β, glycogen synthase kinase-3; HGF, hepatocyte growth factor; IC50, half maximal inhibitory concentration; MAPK, mitogen-activated protein kinase; MET, MNNG HOS transforming gene; MM, multiple myeloma;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Investigation of circulating lncRNAs in B-cell neoplasms

Keywords: MM، میلوم چندگانه; CLL, Chronic Lymphocytic Leukemia; MM, Multiple Myeloma; LncRNA, Long non-coding RNA; TUG1, Taurine Up-regulated Gene 1; MALAT1, Metastasis Associated Lung Adenocarcinoma Transcript 1; HOTAIR, HOX Antisense Intergenic RNA; GAS5, Growth Arrest Specific 5;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Evaluation of digital images for identification and characterization of monoclonal immunoglobulins by immunofixation

Keywords: MM، میلوم چندگانه; LR, Low Resolution; HR, High Resolution; IFX, Immunofixation; SPE, Serum Protein Electrophoresis; MM, Multiple Myeloma; CR, Complete Response; VGPR, Very Good Partial Response; MGUS, Monoclonal Gammopathy of Undetermined Significance; OS, Overall Survival

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Pneumococcal vaccine responses in elderly patients with multiple myeloma, Waldenstrom’s macroglobulinemia, and monoclonal gammopathy of undetermined significance

Keywords: MM، میلوم چندگانه; PPV, 23-valent pneumococcal polysaccharide vaccine; PCV7, 7-valent pneumococcal conjugate vaccine; MGUS, monoclonal gammopathy of undetermined significance; IgG, immunoglobulin G; OPA, opsonophagocytic killing assay; MM, multiple myeloma; WM, Waldenstrom’

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

An activated JAK/STAT3 pathway and CD45 expression are associated with sensitivity to Hsp90 inhibitors in multiple myeloma

Keywords: MM، میلوم چندگانه; MM, Multiple myeloma; Hsp90, Heat shock protein 90 kD; Hsp90-Is, Hsp90 inhibitors; STAT3C, Constitutively active STAT3, 17DMAG, 17-Desmethoxy-17-N,N-dimethylaminoethylamino-geldanamycin, HClMultiple myeloma; Apoptosis; STAT3; Akt; 17DMAG; HSP90

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Risk factors for multiple myeloma: A hospital-based case–control study in Northwest China

Keywords: MM، میلوم چندگانه; MM, multiple myeloma; OR, odds ratios; CI, confidence interval; NHL, non-Hodgkin lymphoma; GCP, genistein combined polysaccharide; EGCG, epigallocatechin-3-gallateMultiple myeloma; Risk factor; Case–control study; Northwest China

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular crosstalk between the proteasome, aggresomes and autophagy: Translational potential and clinical implications

Keywords: MM، میلوم چندگانه; Hsp, heat-shock protein; Ub, ubiquitin; UPS, ubiquitin+proteasome system; OS, overall survival; FDA, Federal Drug Administration; MM, Multiple Myeloma; MCL, Mantle Cell Lymphoma; ER, endoplasmic reticulum; UPR, unfolded protein response; MMCL, multiple my

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Proteasome inhibitor lactacystin augments natural killer cell cytotoxicity of myeloma via downregulation of HLA class I

Keywords: MM، میلوم چندگانه; NK, natural killer; MM, multiple myeloma; HLA, human leukocyte antigen; KIR, killer cell immunoglobulin-like receptor; MIC, MHC class I chain-related molecules; ULBP, UL16-binding proteins; LAC, lactacystin; L, ligand; Allo, allogeneic; HCT, hematopoietic

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

TGF-β-related mechanisms of bone destruction in multiple myeloma

Keywords: MM، میلوم چندگانه; MM, multiple myeloma; sFRP, secreted Frizzled-related protein; DKK1, dikkopf1; TGF-β, transforming growth factor-β; RANKL, receptor activator of nuclear factor-kappaB ligand; OC, osteoclast; BAFF, B-cell-activating factor; APRIL, a proliferation-inducing

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Successful treatment with a modified bortezomib schedule of weekly and longer intervals for patients with refractory/resistance multiple myeloma

Keywords: MM، میلوم چندگانه; NF-κB, nuclear factor kappa B; MM, multiple myeloma; AEs, adverse events; BJP, Bence–Johnes protein; BD, bortezomib and dexamethasone therapy; MP, melphalan pulse predonisolone therapy; PN, peripheral neuropathy; CR, complete response; PR, partial respons

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

NF-κB localization in multiple myeloma plasma cells and mesenchymal cells

Keywords: MM، میلوم چندگانه; NF-κB, Nuclear Factor-kappa B; MM, multiple myeloma; PCs, plasma cells; IL-6, interleukin 6; BM, bone marrow; MCs, mesenchymal cells; IF, immunofluorescence; IHC, immunohistochemistry; EMSA, Electrophoresis Mobility Shift Assay; ELISA, Enzyme-Linked Immun

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Multiple myeloma patients at peripheral blood stem cell harvest: Restricted usage of TCR beta variable families

Keywords: MM، میلوم چندگانه; RT–PCR, reverse transcription–polymerase chain reaction; TCRBV, T-cell receptor beta variable; TCR, T-cell receptor; BV, beta variable; PBMC, peripheral blood mononuclear cells; MM, multiple myeloma; PCR, polymerase chain reaction; ICT, initial chemothera

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Reduced nutritional status among multiple myeloma patients during treatment with high-dose chemotherapy and autologous stem cell support

Keywords: MM، میلوم چندگانه; Anthropometry; Biomarkers; Health-related quality of life; Intensive treatment; Multiple myelomaBMI, Body mass index; CyDex, Cyclophosphamide-dexamethasone therapy; HRQoL, Health-related quality of life; MM, Multiple myeloma; TSF, Triceps skinfold; TSH, T

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Survivin is upregulated in myeloma cell lines cocultured with mesenchymal stem cells

Keywords: MM، میلوم چندگانه; MM, multiple myeloma; ECM, extracelluar matrix; MSCs, mesenchymal stem cells; DNR, daunorubicin; TW, transwell; BM, bone marrow; ASODNs, antisense oligonucleotidesMSCs; Apoptosis; Survivin; Antisense oligonucleotides; Drug resistance

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

HDAC inhibition synergistically enhances alkylator-induced DNA damage responses and apoptosis in multiple myeloma cells

Keywords: MM، میلوم چندگانه; MM, multiple myeloma; HAT, histone acetyltransferase; HDAC, histone deacetylase; HDACi, inhibitor of HDAC; SAHA, suberoylanilide hydroxamic acid; VPA, valproic acid; TRAIL, tumor necrosis factor-related apoptosis-inducing ligand; MAPK, mitogen-activated p

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

A myeloma translocation-like model associating CCND1 with the immunoglobulin heavy-chain locus 3′ enhancers does not promote by itself B-cell malignancies

Keywords: MM، میلوم چندگانه; RR, regulatory region; LCR, locus control region; Ig, immunoglobulin; CSR, class switch recombination; ES, embryonic stem; Q-PCR, quantitative-polymerase chain reaction; MM, multiple myeloma; MCL, mantle cell lymphoma; MGUS, monoclonal gammopathy of undet

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Triptolide alters histone H3K9 and H3K27 methylation state and induces G0/G1 arrest and caspase-dependent apoptosis in multiple myeloma in vitro

Keywords: MM، میلوم چندگانه; MM, multiple myeloma; PRC2, polycomb repressive complex 2; PI, propidium iodide; DMSO, dimethylsulfoxide; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide; PBMC, peripheral blood monocular cells; SDS, sodium dodecylsulfate; TBS, Tris buffe

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Bim is the key mediator of glucocorticoid-induced apoptosis and of its potentiation by rapamycin in human myeloma cells

Keywords: MM، میلوم چندگانه; Dex, dexamethasone; ΔΨm, mitochondrial membrane potential; DiOC6(3), 3,3′-dihexyloxacarbocyanine iodide; TMRE, tetramethylrhodamine ethyl ester; MM, multiple myeloma; PS, phosphatidylserine; RT-MLPA, reverse-transcriptase multiplex ligation-dependent prob

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Anti-proliferative and cytotoxic effects of Strychnos nux-vomica root extract on human multiple myeloma cell line – RPMI 8226

Keywords: MM، میلوم چندگانه; DMSO, dimethyl sulfoxide; DAPI, 4,6,-di amidino-2-2-phenylindole; FBS, fetal bovine serum; MM, multiple myeloma; MTT, 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide; LC–MS, liquid chromatography and mass spectroscopy; PI, propidium iodide;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Personalized medicine: individualized care of cancer patients

Keywords: MM، میلوم چندگانه; CLL, chronic lymphocytic leukemia; CML, chronic myelogenous leukemia; CR, complete remission; CT, cancer-testis; IHC, immunohistochemistry; MM, multiple myeloma; Rb, retinoblastoma protein

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Cooperation between Apo2L/TRAIL and bortezomib in multiple myeloma apoptosis

Keywords: MM، میلوم چندگانه; MM, multiple myeloma; MTT, 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium bromide; PS, phosphatidylserine; ΔΨm, mitochondrial transmembrane potential; DiOC6(3), 3,3′-dihexyloxacarbocyanine iodide; TMRE, tetramethylrhodamine ethyl esterBortezomib; T

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Influx and efflux transport as determinants of melphalan cytotoxicity: Resistance to melphalan in MDR1 overexpressing tumor cell lines

Keywords: MM، میلوم چندگانه; MM, multiple myeloma; MDR1, multidrug resistance protein 1 (also known as P-glycoprotein, official symbol ABCB1); MRP1, multiple drug resistance-associated protein 1 (official symbol ABCC1); LAT, L-type amino acid transporter; TAT, T-type amino acid trans

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Concomitant downregulation of proliferation/survival pathways dependent on FGF-R3, JAK2 and BCMA in human multiple myeloma cells by multi-kinase targeting

Keywords: MM، میلوم چندگانه; aFGF, acidic fibroblast growth factor; BCMA, B-cell maturation antigen; BM, bone marrow; GEP, gene expression profile; HMCL, human multiple myeloma cell line; MM, multiple myeloma; MSC, mesenchymal stromal cellBCMA; FGF-R3; JAK2; Multiple myeloma; RPI-1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Sphingosine 1-phosphate induces Mcl-1 upregulation and protects multiple myeloma cells against apoptosis

Keywords: MM، میلوم چندگانه; S1P, sphingosine-1-phosphate; MM, multiple myeloma; S1PR, S1P receptor; PTX, pertussis toxin; MAPK, mitogen-activated protein kinase; PI3K, Phosphoinositide-3 kinase; SPK, sphingosine kinaseMultiple myeloma; Sphingosine1-phosphate; Mcl-1; Apoptosis

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Neoadjuvant therapy in a patient with clival plasmacytoma associated with multiple myeloma: a case report

Keywords: MM، میلوم چندگانه; CT, computed tomography; Gd, gadolinium; Ig, immunoglobulin; MM, multiple myeloma; MRI, magnetic resonance imaging; VAD, vincristine, adriamycin, and dexamethasoneClivus; Multiple myeloma; Neoadjuvant therapy; Plasmacytoma; Skull base

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma

Keywords: MM، میلوم چندگانه; Dkk1, Dickkopf1; MM, multiple myeloma; BMP-2, bone morphogenetic Protein-2; ALP, alkaline phosphatase; DN-β-cat, dominant negative form of β-catenin; TCF/LEF, T cell factor/Lymphocyte enhance factor.Wnt; Dkk1; BMP-2; Osteoblast; Bone disease; Myeloma

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Relationship between serum levels of vascular endothelial growth factor, hepatocyte growth factor and matrix metalloproteinase-9 with biochemical markers of bone disease in multiple myeloma

Keywords: MM، میلوم چندگانه; MM, Multiple myeloma; MMP-9, matrix metalloproteinase-9; HGF, hepatocyte growth factor; VEGF, vascular endothelial growth factor; Ntx, aminoterminal cross-linked telopeptide; PICP, carboxyterminal propeptide; ELISA, enzyme-linked immunosorbent assayMultip

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Managing and exploiting stress in the antibody factory

Keywords: MM، میلوم چندگانه; DRiPs, defective ribosomal products; ER, endoplasmic reticulum; ERAD, ER associated degradation; Ig, immunoglobulin; MM, multiple myeloma; PDI, protein disulfide isomerase; PI, proteasome inhibitors; RDP, rapidly degraded polypeptides; ROS, reactive oxyge

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Soluble HLA-G: Are they clinically relevant?

Keywords: MM، میلوم چندگانه; ALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia; B-CLL, B cell-chronic lymphocytic leukemia; CSF, cerebrospinal fluid; GB, glioblastoma; MM, multiple myeloma; MS, multiple sclerosis; NB, neuroblastoma; NIND, non-inflammatory neurological di

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Hepatitis C and Risk of Lymphoma: Results of the European Multicenter Case-Control Study EPILYMPH

Keywords: MM، میلوم چندگانه; B-NHL, B-cell non-Hodgkin’s lymphoma; DLBCL, diffuse large B-cell lymphoma; MM, multiple myeloma

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

The immunomodulator AS101 induces growth arrest and apoptosis in Multiple Myeloma: Association with the Akt/Survivin pathway

Keywords: MM، میلوم چندگانه; Inflammation; ImmunopharmacologyCdk, cyclin-dependent kinase; IAPs, inhibitors of apoptosis proteins; IGF-1, insulin-like growth factor 1; MM, Multiple Myeloma; PI, propidium iodide; PI3-K, phosphatidylinositol-3-OH kinaseAS101; Multiple Myeloma; Survivin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Standardized analysis for the quantification of Vβ CDR3 T-cell receptor diversity

Keywords: MM، میلوم چندگانه; TCR, T-Cell Receptor; PBMC, Peripheral Blood Mononuclear Cells; HIV, Human Immunodeficiency Virus; RA, Rheumatoid Arthritis; SLE, Systemic Lupus Erythematosus; MM, Multiple Myeloma; CLL, Chronic Lymphocytic Leukemia.T-cell receptor; Spectratyping; T-cell

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه