Keywords: 5-chloro-2-(2-methylpyrazolo[1,5-a]pyrimidin-5-yl)phenol; 5-chloro-2-(pyrazolo [1,5-a]pyrimidin-7-yl)phenol; Phytopathogens fungi; Antifungal activityHRMS, high resolution mass spectrometry; TLC, thin-layer chromatography; Mp, melting point; IC50, half-ma
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New coumarin complexes of Zn, Cu, Ni and Fe with antiparasitic activity
Keywords: NMR, nuclear magnetic resonance; IR, infrared; UV, ultra violet; Mp, melting point; NBT, nitroblue tetrazolium; DEMEN, Dulbecco/Vogt modified Eagle’s; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NADH, nicotinamide adenine dinucleoti
Exploration of the linkage elements of porcupine antagonists led to potent Wnt signaling pathway inhibitors
Keywords: CYP, cytochrome P450; DCM, dichloromethane; DIPEA, N,N-diisopropylethylamine; DMF, N,N-dimethylformamide; DMSO, dimethyl sulfoxide; DSH, Dishevelled; HPLC, high performance liquid chromatography; mp, melting point; N-G-L, NIH3T3-GRE-Luc reporter gene assa
Design, synthesis, and antibacterial activity of novel Schiff base derivatives of quinazolin-4(3H)-one
Keywords: Schiff base derivative; Quinazolin-4(3H)-one; Synthesis; Ralstonia solanacearum; Antibacterial activityTLC, thin layer chromatography; mp, melting point; IR, Infrared; 1H NMR, proton nuclear magnetic resonance; 13C NMR, carbon nuclear magnetic resonance;
Design, synthesis and insecticidal activities of novel acetamido derivatives containing N-pyridylpyrazole carboxamides
Keywords: Acetamido derivatives; N-pyridylpyrazole carboxamides; Synthesis; Insecticidal activityP. xylostella, Plutella xylostella; mp, melting point; IR, infrared; 1H NMR, proton nuclear magnetic resonance; 13C NMR, carbon nuclear magnetic resonance; LC50, median
Anti-HIV activity of semisynthetic derivatives of andrographolide and computational study of HIV-1 gp120 protein binding
Keywords: Andrographolide derivatives; Cytotoxicity; Anti-HIV activity; Viral envelope protein gp120 bindingAZT, azidothymidine; gp120, glycoprotein 120; Mp, melting point; THF, tetrahydrofuran; Andro, andrographolide
Anti-breast cancer activity of heteroaryl chalcone derivatives
Keywords: Antiproliferative activity; Anticancer agents; Breast cancer; ChalconeCQ, chloroquine; δ ppm, part per million; DMSO, dimethyl sulfoxide; GI50, 50% growth inhibition; IR, infrared; mp, melting point; NMR, nuclear magnetic resonance; ES-MS, electro spray m
Fat, oil and grease deposits in sewers: Characterisation of deposits and formation mechanisms
Keywords: Sewers; Blockages; Fats, oils and grease; FOG; Water hardnessFOG, fat, oil and grease; N, number of samples; SEM, standard error of the mean; SEW, sewer; STW, sewage treatment works; PS, pumping station; MC, moisture content; MP, melting point; VS, volati
Oxidation of alcohols and reduction of aldehydes derived from methyl- and dimethylpyrenes by cDNA-expressed human alcohol dehydrogenases
Keywords: ADH, alcohol dehydrogenase; ALDH, aldehyde dehydrogenase; CYP, cytochrome P450; DMSO, dimethylsulphoxide; HM-MP, hydroxymethyl-methylpyrene; HMP, hydroxymethylpyrene; F-MP, formyl-methylpyrene; FP, formylpyrene; mp, melting point; PAGE, polyacrylamide gel
Lipid lowering effect of S-methyl cysteine sulfoxide from Allium cepa Linn in high cholesterol diet fed rats
Keywords: SMCS, S-methyl cysteine sulfoxide; HMG CoA, hydroxymethyl glutaraldehyde coenzyme A; LDL, low density lipoprotein; HDL, high-density lipoprotein; NADP, nicotinamide adenine dinucleotide phosphate (oxidized form); mp, melting point; TLC, thin layer chromat
Computational approaches to determine drug solubility
Keywords: αH, hydrogen-bond acidity; βH, hydrogen-bond basicity; πH, polarizability term; CLogP, calculated logP; ELogP, experimentally measured logP; logD, distribution coefficient; MP, melting point; PSA, polar surface area; R2, excess molar refraction; relVol, r