Anticonvulsant action of an antagonist of metabotropic glutamate receptors mGluR5 MPEP in immature rats
Keywords: Seizures; Ontogeny; Rat; Metabotropic glutamate receptor; MPEP;
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Stimulation of group I metabotropic glutamate receptors evokes calcium signals and c-jun and c-fos gene expression in human T cells
Keywords: iGlu; ionotropic glutamate; mGlu; metabotropic glutamate; NMDA; N-methyl-d-aspartate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; PLC; phospholipase C; AC; adenylate cyclase; [Ca2+]i; intracellular Ca2+ concentration; mAb; monoclonal anti
Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats
Keywords: Nicotine self-administration; Cue-induced reinstatement; Schedule-induction; Metabotropic glutamate receptor; mGluR5; MPEP; Rat;
Novel pharmacotherapeutic approaches for the treatment of drug addiction and craving
Keywords: 5-HT; serotonin; CRF; corticotropin-releasing factor; DA; dopamine; GABA; γ-aminobutyric acid; GR; glucocorticoid receptor; mGluR; metabotropic glutamate receptor; MPEP; 2-methyl-6-(phenylethynyl)-pyridine; nAChR; nicotinic receptor; NMDA; N-methyl-d-asp
mGluR1 and mGluR5 antagonists in the amygdala inhibit different components of audible and ultrasonic vocalizations in a model of arthritic pain
Keywords: Metabotropic glutamate receptors; Amygdala; Arthritic pain; MPEP; CPCCOEt; Audible vocalizations; Ultrasonic vocalizations; Nociception; Affect; ACSF; artificial cerebrospinal fluid; CeA; central nucleus of the amygdala; CPCCOEt; 7-(hydroxyimino)cycloprop
Periaqueductal grey CB1 cannabinoid and metabotropic glutamate subtype 5 receptors modulate changes in rostral ventromedial medulla neuronal activities induced by subcutaneous formalin in the rat
Keywords: ON-cell; OFF-cell; in vivo extracellular recordings; WIN 55,212-2; metabotropic glutamate receptors; pain; ACSF; artificial cerebrospinal fluid; CFA; complete Freund's adjuvant; CPCCOEt; T7-(hydroxyimino) cyclopropa[b]chromen-1α-carboxylate ethyl ester
Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP
Keywords: Fragile X; mGluR; MPEP; Audiogenic seizures; Open field; fmr1;