دانلود مقالات ISI درباره Mpep + ترجمه فارسی

Impairments of exploration and memory after systemic or prelimbic D1-receptor antagonism in rats

Keywords: D1-receptors; mGlu5; SCH23390; MPEP; Rat; Spatial memory; Object recognition; Exploration;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Effect of the metabotropic glutamate receptor type 5 antagonists MPEP and MTEP in parkinsonian monkeys

Keywords: mGluR5; Dyskinesia; Levodopa; MPTP monkey; MPEP; MTEP;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

The modified Geller-Seifter test in rats was insensitive to GABAB receptor positive modulation or blockade, or 5-HT1A receptor activation

Keywords: Geller-Seifter; GABAB receptor positive modulator; GS39783; CGP46381; Alprazolam; MPEP; 8-OH-DPAT; Predictive validity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Differences in glutamate-mediated calcium responses in the ventral cochlear nucleus and inferior colliculus of the developing rat

Keywords: ACSF; artificial cerebrospinal fluid; [Ca2+]i; free intracellular calcium concentration; CIC; central nucleus of the inferior colliculus; CN; cochlear nucleus; CNS; central nervous system; CHPG; (RS)-2-Chloro-5-hydroxyphenylglycine; DCN; dorsal cochlear n

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Energy deprivation transiently enhances rhythmic inhibitory events in the CA3 hippocampal network in vitro

Keywords: rat; network oscillations; ischemia; organotypic slice cultures; ACF; autocorrelation function; ACSF; artificial cerebrospinal fluid; CCF; cross correlation function; CPP; (R)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid; DHPG; (S)-3,5-dihydroxyphe

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Comparison of the predictive validity of the mirror chamber and elevated plus maze tests in mice

Keywords: Mirror chamber; Elevated plus maze; Locomotor activity; Anxiety; Mouse; Phenotyping; Benzodiazepines; MPEP; Buspirone; Fluoxetine; Venlafaxine; Predictive validity;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Nicotine-induced conditioned place preference in rats: Sex differences and the role of mGluR5 receptors

Keywords: Nicotine; Acetylcholine; Conditioned place preference; Sex differences; mGluR5; MPEP

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Metabotropic glutamate receptor subtype 5 antagonism in learning and memory

Keywords: Metabotropic glutamate receptor 5; Spatial learning; Fear conditioning; Avoidance learning; MPEP; MTEP; Locomotion; (Rat); (Mouse)

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Effects of early and delayed treatment with an mGluR5 antagonist on motor impairment, nigrostriatal damage and neuroinflammation in a rodent model of Parkinson's disease

Keywords: MPEP; 6-Hydroxydopamine; Microglia; Astroglia; Behaviour

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Structure–activity relationships in a novel series of 7-substituted-aryl quinolines and 5-substituted-aryl benzothiazoles at the metabotropic glutamate receptor subtype 5

Keywords: mGluR, metabotropic glutamate receptor; iGluR, ionotropic glutamate receptor; MPEP, 2-methyl-6-(phenylethynyl)pyridine; MTEP, 3-((2-methyl-4-thiazolyl)ethynyl)pyridineMetabotropic glutamate receptor subtype 5; mGluR5; MPEP; MTEP; Drug abuse

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Metabotropic Glutamate Receptor 5 Activity in the Nucleus Accumbens Is Required for the Maintenance of Ethanol Self-Administration in a Rat Genetic Model of High Alcohol Intake

Keywords: Alcohol drinking; alcoholism; caudate; LY379268; mGluR2/3; mGluR5; MPEP; nucleus accumbens; P-rats; prefrontal cortex; reinforcement; self-administration

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Endocannabinoids contribute to metabotropic glutamate receptor-mediated inhibition of GABA release onto hippocampal CA3 pyramidal neurons in an isolated neuron/bouton preparation

Keywords: CB1 receptor; mechanically dissociated neuron; patch-clamp recording; retrograde signaling; spontaneous inhibitory postsynaptic currents; CB1; cannabinoid type 1; DAG; diacylglycerol; DHPG; (RS)-3, 5-dihydroxyphenylglycine; DSI; depolarization-induced sup

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Lithium ameliorates altered glycogen synthase kinase-3 and behavior in a mouse model of Fragile X syndrome

Keywords: FMR1; Glycogen synthase kinase-3; MPEP; Lithium; Autism

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2010 سفارش ترجمه

Inhibitory effects of Group I metabotropic glutamate receptors antagonists on the expression of NMDA receptor NR1 subunit in morphine tolerant rats

Keywords: CNS; central nervous system; iGluRs; ionotropic glutamate receptors; NMDAR; N-methyl-d-aspartic acid receptor; NR1; NMDA-R1 subunit; mGluRs; metabotropic glutamate receptors; mGluR1; mGlu receptor subtype 1; mGluR5; mGlu receptor subtype 5; AIDA; (RS)-1-A

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Effects of mGluR5 and mGluR1 antagonists on anxiety-like behavior and learning in developing rats

Keywords: Metabotropic glutamate receptors; MPEP; AIDA; Anxiety; Learning; Immature rats

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Metabotropic glutamate receptor 5 (mGluR5) antagonists attenuate cocaine priming- and cue-induced reinstatement of cocaine seeking

Keywords: Relapse; Addiction; Psychostimulant; Glutamate; Metabotropic; mGluR5; MPEP; MTEP

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Chronic, systemic treatment with a metabotropic glutamate receptor 5 antagonist in 6-hydroxydopamine partially lesioned rats reverses abnormal firing of dopaminergic neurons

Keywords: Parkinson's disease; Partial lesion; MPEP; Tyrosine hydroxylase; Extracellular recording

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

2-Methyl-6-phenylethynyl-pyridine (MPEP), a non-competitive mGluR5 antagonist, differentially affects the anticonvulsant activity of four conventional antiepileptic drugs against amygdala-kindled seizures in rats

Keywords: MPEP; metabotropic glutamate receptors; conventional antiepileptic drugs; amygdala-kindled seizures

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Metabotropic Glutamate Receptors as Targets for Multipotential Treatment of Neurological Disorders

Keywords: Astrocytes; inflammation; metabotropic glutamate receptors; microglia; neuron; neuroprotection; 4CPG; (S)-4-carboxyphenylglycine; 6-OHDA; 6-hydroxydopamine; Aβ; β-amyloid; AIDA; 1-aminoindan-1, 5-dicarboxylic acid; ALS; amyotrophic lateral sclerosis; AM

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

The R6 lines of transgenic mice: A model for screening new therapies for Huntington's disease

Keywords: AdBDNF/AdNoggin; adenoviral BDNF + adenoviral noggin; AIF; apoptosis inducing factor; asialoEPO; asialoerythropoietin; BDNF; brain-derived neurotrophic factor; CGS; CGS21680; DA; dopamine; DARPP-32; dopamine and cyclic-adenosine monophosphate regulated ph

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2009 سفارش ترجمه

Activation of metabotropic glutamate 5 (mGlu5) receptors induces spontaneous excitatory synaptic currents in layer V pyramidal cells of the rat prefrontal cortex

Keywords: DHPG; MPEP; Hallucinogens; Excitatory postsynaptic currents; Medial prefrontal cortex; Glutamate; Pyramidal cells; mGlu5 receptors;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

Keywords: Fragile X syndrome; Spines; Dendrite branching; MPEP; Fenobam; Prepulse inhibition of startle; Metabotropic glutamate receptor; Primary hippocampal neuron culture

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Effect of a metabotropic glutamate receptor 5 antagonist, MPEP, on the nociceptive response induced by intrathecal injection of excitatory aminoacids, substance P, bradykinin or cytokines in mice

Keywords: Metabotropic glutamate subtype-5 receptor antagonist; MPEP; Nociception; Spinal cord; Intrathecal; Mice

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Neuroprotective effect caused by MPEP, an antagonist of metabotropic glutamate receptor mGluR5, on seizures induced by pilocarpine in 21-day-old rats

Keywords: Seizure; Pilocarpine; Young rat; Metabotropic glutamate receptor; MPEP; Oxidative stress

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Effects of the mGluR2/3 agonist LY379268 and the mGluR5 antagonist MPEP on handling-induced convulsions during ethanol withdrawal in mice

Keywords: Alcohol withdrawal; Sensitization; Seizure; Handling-induced convulsion; Metabotropic glutamate receptors; MPEP; LY379268

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Cue-induced reinstatement of alcohol-seeking behavior is associated with increased ERK1/2 phosphorylation in specific limbic brain regions: Blockade by the mGluR5 antagonist MPEP

Keywords: Alcoholism; Alcohol reinforcement; Relapse; Cue-induced reinstatement; ERK/MAPK; ERK1/2; mGluR5; MPEP; Alcohol-preferring P-rats

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Glutamate receptor ligands attenuate allodynia and hyperalgesia and potentiate morphine effects in a mouse model of neuropathic pain

Keywords: Neuropathic pain; MPEP; LY379268; AMN082; Morphine;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Research reportMGlu5 antagonism impairs exploration and memory of spatial and non-spatial stimuli in rats

Keywords: mGlu5 receptor; Antagonist; MPEP; Rat; Exploration; Maze learning; Object recognition; Prelimbic cortex;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Selective induction of metabotropic glutamate receptor 1- and metabotropic glutamate receptor 5-dependent chemical long-term potentiation at oriens/alveus interneuron synapses of mouse hippocampus

Keywords: inhibitory interneurons; plasticity; mGluR1 knockout mice; DHPG; MPEP; LY367385; ACSF; artificial cerebrospinal fluid; AMPAR; AMPA receptor; AP-5; dl-2-amino-5-phosphonovaleric acid; CI-AMPA; calcium-impermeable AMPA receptor; CP-AMPAR; calcium-permeable

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2008 سفارش ترجمه

Rational design of 7-arylquinolines as non-competitive metabotropic glutamate receptor subtype 5 antagonists

Keywords: mGluR5; Antagonist; MPEP

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Interleukin-18 mediated inhibition of LTP in the rat dentate gyrus is attenuated in the presence of mGluR antagonists

Keywords: Interleukin-18; Long-term potentiation; Metabotropic glutamate receptors; MPEP; MTPG;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Rational design, synthesis, and structure–activity relationship of benzoxazolones: New potent mglu5 receptor antagonists based on the fenobam structure

Keywords: mGluR5; Fenobam; Anxiety; MPEP; Benzoxazolone

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Synthesis and biological evaluation of fenobam analogs as mGlu5 receptor antagonists

Keywords: mGluR5; Fenobam; Anxiety; MPEP; Pharmacophore

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Blockade of metabotropic glutamate receptor 5 activation inhibits mechanical hypersensitivity following abdominal surgery

Keywords: Metabotropic glutamate receptor 5; Post-surgical pain; MPEP; Hyperalgesia;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Peripheral metabotropic glutamate receptor 5 mediates mechanical hypersensitivity in craniofacial muscle via protein kinase C dependent mechanisms

Keywords: masseter; rat; behavioral model; glutamate; AUC; area under the curve; CPCCOEt; 7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxylate ethyl ester; DHPG; R,S-3,5-dihydroxyphenylglycol; DRG; dorsal root ganglia; EAA; excitatory amino acid; mGluR; metabotropic

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

The effects of the mGluR5 antagonist MPEP and the mGluR2/3 antagonist LY341495 on rats' performance in the 5-choice serial reaction time task

Keywords: Attention; Metabotropic glutamate receptors; MPEP; LY341495; Schizophrenia; Rat

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Different effects of ionotropic and metabotropic glutamate receptor antagonists on attention and the attentional properties of nicotine

Keywords: Nicotine; Glutamate; CPP; MPEP; NMDA; mGlu5; Behaviour; Attention

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Interactive effects of the mGlu5 receptor antagonist MPEP and the mGlu2/3 receptor antagonist LY341495 on nicotine self-administration and reward deficits associated with nicotine withdrawal in rats

Keywords: LY341495; MPEP; Metabotropic glutamate receptor; Nicotine; Self-administration; Intracranial self-stimulation; Reward; Dependence; Withdrawal

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Two-methyl-6-phenylethynyl-pyridine (MPEP), a metabotropic glutamate receptor 5 antagonist, with low doses of MK801 and diazepam: A novel approach for controlling status epilepticus

Keywords: Group I metabotropic glutamate receptor; MPEP; Status epilepticus; Neuroprotection

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Metabotropic glutamate receptor ligands as possible anxiolytic and antidepressant drugs

Keywords: Anxiety; Depression; LY354740; mGlu receptors; MPEP; MTEPBehavioral test; 4PT, 4-plate test; CER, conditioned emotional response; CFC, contextual fear conditioning; CFS, conditioned fear stress; CMS, chronic mild stress; EZM, elevated zero maze; FPS, fear

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2007 سفارش ترجمه

In vitro metabolic studies on the selective metabotropic glutamate receptor sub-type 5 (mGluR5) antagonist 3-[(2-methyl-1,3-thiazol-4-yl) ethynyl]-pyridine (MTEP)

Keywords: Metabotropic glutamate receptor; Drug metabolism; CYP1A2; CYP2C; MPEP; MTEP

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

Regulation of phosphorylation of NMDA receptor NR1 subunits in the rat neostriatum by group I metabotropic glutamate receptors in vivo

Keywords: Dopamine; mGluR; Serine; Nucleus accumbens; DHPG; PHCCC; MPEP;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Transient lower esophageal sphincter relaxations in dogs are inhibited by a metabotropic glutamate receptor 5 antagonist

Keywords: Glutamate; Lower esophageal sphincter; 2-methyl-6-(phenylethynyl)-pyridine; MPEP; Gastroesophageal reflux;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2005 سفارش ترجمه

Functionalization at position 3 of the phenyl ring of the potent mGluR5 noncompetitive antagonists MPEP

Keywords: Metabotropic; mGluR5; MPEP; Antagonist;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه

Chronic exposure to ammonia alters the modulation of phosphorylation of microtubule-associated protein 2 by metabotropic glutamate receptors 1 and 5 in cerebellar neurons in culture

Keywords: hyperammonemia; MAP-2 phosphorylation; hepatic encephalopathy; glutamate receptors; rat; DHPG; (S)-3,5-dihydroxyphenylglycine; L-CCG-I; (2S,3S,4S)-CCG/(2S, 1′S,2′S)-2-(carboxycyclopropyl)glycine; MAP-2; microtubule-associated protein 2; mGluRs; metabo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Effects of metabotropic glutamate receptor 5 on latent inhibition in conditioned taste aversion

Keywords: Latent inhibition; Metabotropic glutamate receptor 5; Conditioned taste aversion; Classical conditioning; MPEP; Rat;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Role of central and peripheral mGluR5 receptors in post-operative pain in rats

Keywords: MPEP; Skin incision; Weight-bearing difference; Non-evoked post-operative pain;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Inhibition of Transient Lower Esophageal Sphincter Relaxation and Gastroesophageal Reflux by Metabotropic Glutamate Receptor Ligands

Keywords: GABA; γ-aminobutyric acid; GERD; gastroesophageal reflux disease; L-AP4; L-(+)-2-amino-4-phosphonobutyric acid; mGluR; metabotropic glutamate receptor; MPEP; 2-methyl-6-(phenylethynyl)-pyridine; MTEP; 3-([2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine; NMDA;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Methoxyphenylethynyl, methoxypyridylethynyl and phenylethynyl derivatives of pyridine: synthesis, radiolabeling and evaluation of new PET ligands for metabotropic glutamate subtype 5 receptors

Keywords: MgluR5; PET; MPEP; M-MPEP; M-PEPy; Carbon-11;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Group I metabotropic glutamate receptors reduce excitotoxic injury and may facilitate neurogenesis

Keywords: DHPG; U73122; TOAD-64; LY367385; MPEP; EPSC;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه