کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6287729 1615633 2010 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Differences in glutamate-mediated calcium responses in the ventral cochlear nucleus and inferior colliculus of the developing rat
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی سیستم های حسی
پیش نمایش صفحه اول مقاله
Differences in glutamate-mediated calcium responses in the ventral cochlear nucleus and inferior colliculus of the developing rat
چکیده انگلیسی
Both mGluR1 and mGluR5 subtypes of group I mGluRs were present in the CIC and the VCN. However, Group I mGluR [Ca2+]i responses elicited by DHPG were two fold higher in CIC than in VCN neurons. Therefore, our findings suggest that Ca2+ signalling in auditory neurons may be differentially regulated at different levels of the auditory pathway through preferential activation of different classes of glutamate receptors, which may have implications for hierarchical auditory signal processing and plasticity, at least during the early developmental stages of hearing.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Hearing Research - Volume 267, Issues 1–2, 1 August 2010, Pages 46-53
نویسندگان
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