Keywords: ALS; Amyotrophic lateral sclerosis; DMD; DuchenneMuscular Dystrophy; SMA; Spinalmuscular atrophy; FAP; FamilialAmyloid Polyneuropathy; OD; Orphandisease; ORD; Officeof Rare Diseases; NIH; NationalInstitutes of Health; sALS; SporadicALS; fALS; FamilialALS;
مقالات ISI (ترجمه نشده)
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Keywords: Kainate receptors; N-terminal domain; Ligand-binding domain; Crystal structures; Ligands; Mutations; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate; iGluRs; ionotropic glutamate receptors; LBDs; ligand-binding domains; NMDA; N-methyl-d-aspartate;
Keywords: CGRP; calcitonin gene related peptide; CSD; cortical spreading depression; NSAIDs; non-steroidal anti-inflammatory drugs; 5-HT; 5-hydroxytryptamine; 5-HIAA; 5-hydroxyindoleacetic acid; NO; nitric oxide (NO); TG; trigeminal ganglion; TNC; trigeminal nucleu
Keywords: CON; control; DAG; diacylglycerol; GD; gestational day; HIP; hippocampus; iGluRs; ionotropic glutamate receptors; LTD; long-term depression; LTP; long-term potentiation; MB; mammillary body; mGluRs; metabotropic glutamate receptors; MWM; Morris water maze
Keywords: BSA; bovine serum albumin; DAPI; 4â²,6-diamidino-2-phenylindole; DRG; dorsal root ganglia; GLS; glutaminase; HRP; horseradish peroxidase; ICG; intrinsic cardiac ganglia; iGluRs; ionotropic glutamate receptors; MGI; mean gray intensity; mGluRs; metabotrop
Keywords: BCA; bicinchoninic acid; EPM; elevated plus maze; GD; gestational day; iGluRs; ionotropic glutamate receptors; LSD; least significant difference; mGluRs; metabotropic glutamate receptors; PCMS; prenatal chronic mild stress; PKC; protein kinase C; PND; pos
Keywords: AD; amygdala; ANOVA; analysis of variance; CMS; chronic mild stress; FST; forced swimming test; GD; gestational day; GluR; glutamate receptor; HIP; hippocampus; iGluRs; ionotropic glutamate receptors; mGluRs; metabotropic glutamate receptors; NMDA; N-meth
Keywords: ANOVA; analysis of variance; GABA; γ-aminobutyric acid; SEM; standard error of the mean; NMDA; N-methyl-d-aspartate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; iGluRs; ionotropic glutamate receptors; mGluRs; metabotropic glutamate recep
Ionotropic glutamate receptors (iGluRs) of the delta family (GluD1 and GluD2) and synaptogenesis
Keywords: iGluRs; GluD1; GluD2; Synaptogenesis; Autism spectrum disorder (ASD); Schizophrenia (SCZ);
Radiosynthesis and preliminary PET evaluation of 18F-labeled 2-(1-(3-fluorophenyl)-2-oxo-5-(pyrimidin-2-yl)-1,2-dihydropyridin-3-yl)benzonitrile for imaging AMPA receptors
Keywords: mGluRs; metabotropic glutamate receptors; iGluRs; ionotropic glutamate receptors; NMDA; N-methyl-d-aspartate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; PET; positron emission tomography; CNS; central nervous system; TEA[18F]; [18F]tetra
Emerging novel roles of neuropeptide Y in the retina: From neuromodulation to neuroprotection
Keywords: BrdU; 5-bromo-2â²-deoxyuridine; [Ca2+]i; intracellular calcium; CNS; central nervous system; DPP-IV; dipeptidyl peptidase IV; E18; embrionic day 18; ERK; extracellular signal-regulated kinases; GABA; γ-aminobutyric acid; GAD 65; glutamic acid decarboxyl
Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors
Keywords: AMPA; (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionate; CBG-IV; (2S,1â²R,2â²S)-2-(2â²-carboxycyclobutyl)glycine; CNS; central nervous system; iGluRs; ionotropic glutamate receptors; KA; kainate; LBD; ligand binding domain; NMDA; N-methyl-d-asp
3-Hydroxy-1H-quinazoline-2,4-dione derivatives as new antagonists at ionotropic glutamate receptors: Molecular modeling and pharmacological studies
Keywords: Ionotropic glutamate receptors; 3-Hydroxyquinazoline-2,4-diones; AMPA receptor antagonists; Kainate receptor antagonists; Neuroprotective agents; Ligand-receptor modeling studies; Glu; glutamate; iGluRs; ionotropic glutamate receptors; NMDA; N-methyl-d-
Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate
Keywords: AMPA; 2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid; ATD; amino-terminal domain; CTD; carboxy-terminal domain; iGluRs; ionotropic glutamate receptors; IPTG; isopropyl-β-d-thiogalactopyranoside; KARs; kainate receptors; LBD; ligand binding dom
Differences in glutamate-mediated calcium responses in the ventral cochlear nucleus and inferior colliculus of the developing rat
Keywords: ACSF; artificial cerebrospinal fluid; [Ca2+]i; free intracellular calcium concentration; CIC; central nucleus of the inferior colliculus; CN; cochlear nucleus; CNS; central nervous system; CHPG; (RS)-2-Chloro-5-hydroxyphenylglycine; DCN; dorsal cochlear n
Sensitization of rat facial cutaneous mechanoreceptors by activation of peripheral N-methyl-d-aspartate receptors
Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ANOVA; Analysis of variance; APV; 2-amino-5-phosphonovalerate; CGRP; Calcitonin gene-related peptide; CV; Conduction velocity; CY3; Cyanine; EC50; Half maximal effective concentration; ELISA; En
Inhibitory effects of Group I metabotropic glutamate receptors antagonists on the expression of NMDA receptor NR1 subunit in morphine tolerant rats
Keywords: CNS; central nervous system; iGluRs; ionotropic glutamate receptors; NMDAR; N-methyl-d-aspartic acid receptor; NR1; NMDA-R1 subunit; mGluRs; metabotropic glutamate receptors; mGluR1; mGlu receptor subtype 1; mGluR5; mGlu receptor subtype 5; AIDA; (RS)-1-A
GABAA and strychnine-sensitive glycine receptors modulate N-methyl-d-aspartate-evoked acetylcholine release from rat spinal motoneurons: A possible role in neuroprotection
Keywords: primary cultures; ALS; radiolabeled neurotransmitter; calcium channels; NMDA receptor subunit; ACh; acetylcholine; ACM; astrocyte-conditioned medium; ALS; amyotrophic lateral sclerosis; ANOVA; analysis of variance; DMEM; Dulbecco's modified Eagle's medium
4-Alkylated homoibotenic acid (HIBO) analogues: Versatile pharmacological agents with diverse selectivity profiles towards metabotropic and ionotropic glutamate receptor subtypes
Keywords: iGluRs; mGluRs; AMPA receptors; GluR5; Receptor selectivity;
Ionotropic glutamate receptors and glutamate transporters are involved in necrotic neuronal cell death induced by oxygen-glucose deprivation of hippocampal slice cultures
Keywords: neuroprotection; neurodegeneration; cerebral ischemia; GLT-1; GLAST; GDNF; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CNQX; 6-cyano-7-nitroquinoxaline-2,3-(1H,4H)-dione; dl-TBOA; dl-threo-beta-benzyloxyaspartate; FJ-B; Fluoro-Jade B; GDN