Keywords: 3-HK; 3-hydroxykynurenine; 3-NP; 3-nitropropionic acid; 6âOHDA; 6-hydroxidopamine; AADC; aromatic amino acid decarboxylase; ACA; anterior cerebral artery; ADP; adenosine-5â²-diphosphate; ALDH; aldehyde dehydrogenases; ALS; amyotrophic lateral sclerosis
مقالات ISI (ترجمه نشده)
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Keywords: CaMKII; Ca2+-calmodulin-dependent kinase II; ER; endoplasmic reticulum; GABAARs; type-A GABA receptors; IICR; IP3 receptor-dependent calcium release; GLT1; glutamate transporter 1; GlyR; glycine receptor GlyR; mGluRs; metabotropic glutamate receptors; nAc
Keywords: ACh; Acetylcholine; A-P; Anterior-posterior; AChE; Acetylcholinesterase; AD; Alzheimer's disease; Akt; Serine/threonine kinase; ALA; Aplpha linoleic acid; AM; Amygdala; AMPA; α-Amino- 3-hydroxy-5-methyl-4-isoxazolepropionic acid; AP-7; 2-amino-7-phosph
Keywords: CGRP; calcitonin gene related peptide; CSD; cortical spreading depression; NSAIDs; non-steroidal anti-inflammatory drugs; 5-HT; 5-hydroxytryptamine; 5-HIAA; 5-hydroxyindoleacetic acid; NO; nitric oxide (NO); TG; trigeminal ganglion; TNC; trigeminal nucleu
Keywords: AIDA; 1-Aminoindan-1,5-dicarboxylic acid; aCSF; artificial cerebrospinal fluid; ANOVA; analysis of variance; eEF-2; eukaryotic elongation factor-2; ERK-2; extracellular signal-regulated kinase 2; FMRP; fragile X mental retardation protein; mGluRs; metabot
Keywords: 1,25-D3; 1,25-Dihydroxy vitamin D3; ACF; Aberrant crypt foci; AC; Adenylate cyclase; ADH; Autosomal dominant hypocalcaemia; CaSR; Calcium-sensing receptor; cAMP; Cyclic adenosine 3â²,5â²-monophosphate; Cai2+; Â Intracellular free ionised calcium; Cao2+;
Keywords: CON; control; DAG; diacylglycerol; GD; gestational day; HIP; hippocampus; iGluRs; ionotropic glutamate receptors; LTD; long-term depression; LTP; long-term potentiation; MB; mammillary body; mGluRs; metabotropic glutamate receptors; MWM; Morris water maze
Keywords: BSA; bovine serum albumin; DAPI; 4â²,6-diamidino-2-phenylindole; DRG; dorsal root ganglia; GLS; glutaminase; HRP; horseradish peroxidase; ICG; intrinsic cardiac ganglia; iGluRs; ionotropic glutamate receptors; MGI; mean gray intensity; mGluRs; metabotrop
Keywords: ACC; anterior cingulate cortex; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CTA; conditioned taste aversion; EPSCs; excitatory postsynaptic currents; IC; insular cortex; LFS; low-frequency stimulation; LTD; long-term depression; LTP; long
Keywords: ASDs; Autism spectrum disorders; CNV; copy number variant; eIPSC; evoked IPSC; FMRP; fragile X mental retardation protein; FXS; fragile X syndrome; LOH; loss of heterozygosity; LTD; long-term depression; LTP; long-term potentiation; mEPSCs; miniature exci
Keywords: ASD; autism spectrum disorder; ELS; early-life seizure; FMRP; fragile X mental retardation protein; ID; intellectual disability; KA; kainic acid; KO; knockout; mGluRs; metabotropic glutamate receptors; mLTD; mGluR-mediated long-term depression; P; postnat
Keywords: AD; amygdala; ANOVA; analysis of variance; CMS; chronic mild stress; FST; forced swimming test; GD; gestational day; GluR; glutamate receptor; HIP; hippocampus; iGluRs; ionotropic glutamate receptors; mGluRs; metabotropic glutamate receptors; NMDA; N-meth
Keywords: BCA; bicinchoninic acid; EPM; elevated plus maze; GD; gestational day; iGluRs; ionotropic glutamate receptors; LSD; least significant difference; mGluRs; metabotropic glutamate receptors; PCMS; prenatal chronic mild stress; PKC; protein kinase C; PND; pos
Keywords: Dendritic spine; Synaptic plasticity; Neurodegenerative diseases; Psychiatric disorders; Glutamate receptor; Calcium signaling; ADHD; attention deficit hypersensitive disorders; FXS; Fragile X-syndrome; CNS; central nervous system; GABA; gamma amino butyr
Keywords: CASK; calcium/calmodulin-dependent serine protein kinase; COS-7; African green monkey kidney fibroblast-like cell line; Drp1; dynamin-related protein 1; FAK; focal adhesion kinase; hnRNPA2B1; heterogeneous nuclear ribonucleoprotein A2B1; K2P; potassium se
Keywords: ANOVA; analysis of variance; GABA; γ-aminobutyric acid; SEM; standard error of the mean; NMDA; N-methyl-d-aspartate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; iGluRs; ionotropic glutamate receptors; mGluRs; metabotropic glutamate recep
Keywords: mGluRs; Prefrontal cortex; Basolateral amygdala; Inflammatory pain; Rat;
Toll-like receptor-4 regulates anxiety-like behavior and DARPP-32 phosphorylation
Keywords: TLR4; Anxiety; Emotion; mGluRs; DARPP-32;
Astrocytes in Memory Function: Pioneering Findings and Future Directions
Keywords: AgRP; agouti-related peptide; ATP; adenosine triphosphate; CB1Rs; cannabinoid 1 receptors; ChR; channelrhodopsin; GPCRs; G-protein-coupled receptors; hAPP; human amyloid precursor protein; LTD; long-term depression; LTP; long-term potentiation; mGluRs; me
Molecular basis for the regulation of the circadian clock kinases CK1δ and CK1ε
Keywords: ATP; adenosine triphosphate; CK1; casein kinase 1; CK2; casein kinase 2; CTD; C-terminal domain; TTFL; transcriptional and translational feedback loop; GSK-3β; glycogen synthase kinase 3β; MEFs; mouse embryonic fibroblast cells; ConA; concanavalin A; LP
Effects of repeated cocaine exposure and withdrawal on voluntary ethanol drinking, and the expression of glial glutamate transporters in mesocorticolimbic system of P rats
Keywords: GLT-1; glutamate transporter type 1; xCT; cystine/glutamate transporter; GLAST; glutamate aspartate transporter; NAc; nucleus accumbens; P; alcohol preferring; mPFC; medial prefrontal cortex; GLT-1; xCT; GLAST; mGluRs; mPFC; NAc;
Radiosynthesis and preliminary PET evaluation of 18F-labeled 2-(1-(3-fluorophenyl)-2-oxo-5-(pyrimidin-2-yl)-1,2-dihydropyridin-3-yl)benzonitrile for imaging AMPA receptors
Keywords: mGluRs; metabotropic glutamate receptors; iGluRs; ionotropic glutamate receptors; NMDA; N-methyl-d-aspartate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; PET; positron emission tomography; CNS; central nervous system; TEA[18F]; [18F]tetra
Research reportCB1 receptor antagonism prevents long-term hyperexcitability after head injury by regulation of dynorphin-KOR system and mGluR5 in rat hippocampus
Keywords: CB; cannabinoid; KOR; κ opioid receptor; FPI; fluid percussion injury; PTZ; pentylenetetrazole; mGluRs; metabotropic glutamate receptors; GABA; γ-aminobutyric acid; eCBs; endocannabinoid; PTE; post-traumatic epilepsy; Post-traumatic epilepsy; Prevention
Beta-arrestin1 and 2 differently modulate metabotropic glutamate receptor 7 signaling in rat developmental sevoflurane-induced neuronal apoptosis
Keywords: AMN082; N,Nâ²-bis(diphenylmethyl)-1,2-ethanediamine dihydrochloride; CBP; CREB binding protein; CNS; central nervous system; CREB; cyclic adenosine 3â²,5â²-monophosphate response element binding protein; Curcumin; diferuloylmethane; DIV; days in vitro;
LY395756, an mGluR2 agonist and mGluR3 antagonist, enhances NMDA receptor expression and function in the normal adult rat prefrontal cortex, but fails to improve working memory and reverse MK801-induced working memory impairment
Keywords: 3,5-DHPG; 3,5-dihydroxyphenylglycine; AC; adenylate cyclase; ACPD; 1-amino-1,3-dicarboxycyclopentane; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPH; amphetamine; APDC; dihydroxyphenylglycine; cAMP; cyclic-adenosine monophosphate; DCG-I
Down-regulation of Homer1b/c attenuates group I metabotropic glutamate receptors dependent Ca2+ signaling through regulating endoplasmic reticulum Ca2+ release in PC12 cells
Keywords: mGluRs; Homer; RNAi; Calcium; Endoplasmic reticulum;
Emerging novel roles of neuropeptide Y in the retina: From neuromodulation to neuroprotection
Keywords: BrdU; 5-bromo-2â²-deoxyuridine; [Ca2+]i; intracellular calcium; CNS; central nervous system; DPP-IV; dipeptidyl peptidase IV; E18; embrionic day 18; ERK; extracellular signal-regulated kinases; GABA; γ-aminobutyric acid; GAD 65; glutamic acid decarboxyl
Enhanced excitatory synaptic network activity following transient group I metabotropic glutamate activation
Keywords: ACPD; (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid; AHP; afterhyperpolarizing; 4-AP; 4-aminopyridine; APV; d,l-2-amino-5-phosphonovaleric acid; ASCF; artificial cerebrospinal fluid; CNQX; 6-cyano-7-nitoquinoxaline-2,3-dione; DHPG; (S)-3,5-dihydroxyph
Glycine release is regulated by metabotropic glutamate receptors sensitive to mGluR2/3 ligands and activated by N-acetylaspartylglutamate (NAAG)
Keywords: Glycine release; Glutamate receptors; mGluR3; NAAG; Spinal cord synaptosomes; β-NAAG; N-acetylaspartyl-β-linked glutamate; mGluRs; metabotropic glutamate receptors; NAAG; N-acetylaspartylglutamate;
Regional regulation of glutamate signaling during cuprizone-induced demyelination in the brain
Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; BSA; bovine serum albumin; CC; corpus callosum; CNS; central nervous system; EAAT; excitatory amino acid transporter; EAE; experimental allergic encephalomyelitis; ECL; enhanced chemiluminescenc
Enhancement of long-term depression by soluble amyloid β protein in rat hippocampus is mediated by metabotropic glutamate receptor and involves activation of p38MAPK, STEP and caspase-3
Keywords: Aβ; amyloid-β protein; AD; Alzheimer's disease; AMPAR; a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; DHPG; 3,5-dihydroxyphenylglycine; EPSP; excitatory postsynaptic potential; fEPSPs; field excitatory postsynaptic potentials; LTP; lon
Metabotropic glutamate subtype 7 and 8 receptors oppositely modulate cardiac nociception in the rat nucleus tractus solitarius
Keywords: ACSF; artificial cerebrospinal fluid; AMN082; N,N'-diphenylmethyl-1,2-ethanediamine dihydrochloride; DCPG; (S)-3,4-dicarboxyphenylglycine; EMG; electromyogram; GABA; γ-aminobutyric acid; l-AP4; l-(+)-2-Amino-4-phosphonobutyric acid; mGluRs; metabotropi
System xcâ regulates microglia and macrophage glutamate excitotoxicity in vivo
Keywords: CNS; central nervous system; LPS; lipopolysaccharide; OPC; oligodendrocyte progenitor cell; GSH; glutathione; TLR; toll-like receptor; NBQX; 2,3-dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide; DAB; diaminobenzidine; DAPI; 4â²,6-diamidi
Anxiety in Parkinson's disease: A critical review of experimental and clinical studies
Keywords: Parkinson's disease; Anxiety; Clinical studies; Animal models; Review; BLA; basolateral nucleus of the amygdala; BDZs; benzodiazepines; CNS; central nervous system; DSM; Diagnostic and Statistical Manual of Mental Disorders; DA; dopamine; DOPAC; 3,4-dih
The effects of metabotropic glutamate receptor 7 allosteric agonist N,Nâ²-dibenzhydrylethane-1,2-diamine dihydrochloride on developmental sevoflurane neurotoxicity: role of extracellular signal-regulated kinase 1 and 2 mitogen-activated protein kinase si
Keywords: mGluRs; sevoflurane; neurotoxicity; MAPK; learning and memory; hippocampus; AMN082; N,Nâ²-dibenzhydrylethane-1,2-diamine dihydrochloride; EDTA; ethylenediaminetetraacetic acid; ERK1/2; extracellular signal-regulated kinase 1 and 2; FCM; Flow cytometry; H
Exploration of structure-based drug design opportunities for mGluRs
Keywords: GPCRs; mGluRs; Transmembrane domain
Molecular imaging in neuroscience research with small-animal PET in rodents
Keywords: ACh; acetylcholine; BP; binding potential; CBZ; central benzodiazepine; [18F]FDG; 2-deoxy-2-[18F]fluoro-d-glucose; FFMZ; fluoroflumazenil; GABA; γ-aminobutyric acid; 5-HT; 5-hydroxytryptamine (serotonin); KA; kainic acid; mGluRs; metabotropic glutamate r
Significance of NMDA receptor-related glutamatergic amino acid levels in peripheral blood of patients with schizophrenia
Keywords: BPRS; Brief Psychiatry Rating Scale; CSF; cerebrospinal fluid; DAO; d-amino acid-oxidase; GLS1 and GLS2; glutaminase 1 and 2; MRS; magnetic resonance spectroscopy; mGluRs; metabotropic glutamate receptors; NMDA; N-methyl d-aspartate; PCP; phencyclidine; P
A novel, extremely fast, feedback inhibition of glutamate release in the crayfish neuromuscular junction
Keywords: feedback inhibition; GPCRs; mGluRs; neurotransmitter release; glutamate release; presynaptic modulationDI, dose-inhibition; DR, dose-response; ENTC, excitatory nerve terminal current; EPSC, excitatory postsynaptic current; EPSP, excitatory postsynaptic po
Attention deficit induced by blockade of N-methyl d-aspartate receptors in the prefrontal cortex is associated with enhanced glutamate release and cAMP response element binding protein phosphorylation: role of metabotropic glutamate receptors 2/3
Keywords: NMDA receptor antagonist; LY379268; glutamate release; p-S133CREB; 5-choice serial reaction time task; attention; aCSF; artificial cerebrospinal fluid; ANOVA; analysis of variance; CPu; caudate-putamen; CREB; cAMP response element binding protein; FC; fro
The acute and chronic effects of combined antipsychotic-mood stabilizing treatment on the expression of cortical and striatal postsynaptic density genes
Keywords: PSD; postsynaptic density; mGluRs; metabotropic glutamate receptors; NMDAR; N-methyl-D-aspartate glutamate receptor; IEGs; immediate-early genes; PBS; phosphate buffered saline; SSC; saline sodium citrate solution; ROIs; regions of interest; ANOVA; analys
Dynamic regulation of midbrain dopamine neuron activity: intrinsic, synaptic, and plasticity mechanisms
Keywords: burst; pause; firing pattern; reward prediction error; disinhibition; synaptic plasticity; Ach; acetylcholine; DA; dopamine; Ih; hyperpolarization-activated cationic conductance; IP3; inositol 1,4,5-trisphosphate; LDTg; laterodorsal tegmental nucleus; mGl
Differences in glutamate-mediated calcium responses in the ventral cochlear nucleus and inferior colliculus of the developing rat
Keywords: ACSF; artificial cerebrospinal fluid; [Ca2+]i; free intracellular calcium concentration; CIC; central nucleus of the inferior colliculus; CN; cochlear nucleus; CNS; central nervous system; CHPG; (RS)-2-Chloro-5-hydroxyphenylglycine; DCN; dorsal cochlear n
Energy deprivation transiently enhances rhythmic inhibitory events in the CA3 hippocampal network in vitro
Keywords: rat; network oscillations; ischemia; organotypic slice cultures; ACF; autocorrelation function; ACSF; artificial cerebrospinal fluid; CCF; cross correlation function; CPP; (R)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid; DHPG; (S)-3,5-dihydroxyphe
Differential Roles of Peripheral Metabotropic Glutamate Receptors in Bee Venom-Induced Nociception and Inflammation in Conscious Rats
Keywords: Bee venom; mGluRs; persistent spontaneous nociception; hyperalgesia; inflammation
mGluR-mediated and endocannabinoid-dependent long-term depression in the hilar region of the rat dentate gyrus
Keywords: Endocannabinoids; mGluRs; LTD; Dentate gyrus; Synaptic plasticity; Electrophysiology
Minocycline prevents impaired glial glutamate uptake in the spinal sensory synapses of neuropathic rats
Keywords: glutamate transporters; glutamate receptors; spinal sensory processing; nociception; glia; pain; aCSF; artificial cerebrospinal fluid; DHK; dihydrokainic acid; DNQX; 6,7-dinitroquinoxaline-2,3-dione; EPSCs; excitatory postsynaptic currents; GFAP; glial fi
Inhibitory effects of Group I metabotropic glutamate receptors antagonists on the expression of NMDA receptor NR1 subunit in morphine tolerant rats
Keywords: CNS; central nervous system; iGluRs; ionotropic glutamate receptors; NMDAR; N-methyl-d-aspartic acid receptor; NR1; NMDA-R1 subunit; mGluRs; metabotropic glutamate receptors; mGluR1; mGlu receptor subtype 1; mGluR5; mGlu receptor subtype 5; AIDA; (RS)-1-A
Homocysteine-induced acute excitotoxicity in cerebellar granule cells in vitro is accompanied by PP2A-mediated dephosphorylation of tau
Keywords: Cerebellar granule cells; Excitotoxicity; Homocysteine; mGluRs; NMDA receptors; Phosphorylation; Tau protein; PP2A
Effects of activation of group III metabotropic glutamate receptors on spinal synaptic transmission in a rat model of neuropathic pain
Keywords: CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; CPPG; (RS)-α-cyclopropyl-4-phosphonophenylglycine; eEPSCs; evoked excitatory postsynaptic current; GDP-β-S; guanosine 5â²-O-(2-thiodiphosphate); IPSC; inhibitory postsynaptic current; l-AP4; l(+)-2-amino-4-ph