Keywords: گیرنده های گلوتامات یوناتروپیک; Kainate receptors; N-terminal domain; Ligand-binding domain; Crystal structures; Ligands; Mutations; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate; iGluRs; ionotropic glutamate receptors; LBDs; ligand-binding domains; NMDA; N-methyl-d-aspartate;
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Keywords: گیرنده های گلوتامات یوناتروپیک; CGRP; calcitonin gene related peptide; CSD; cortical spreading depression; NSAIDs; non-steroidal anti-inflammatory drugs; 5-HT; 5-hydroxytryptamine; 5-HIAA; 5-hydroxyindoleacetic acid; NO; nitric oxide (NO); TG; trigeminal ganglion; TNC; trigeminal nucleu
Keywords: گیرنده های گلوتامات یوناتروپیک; Ionotropic glutamate receptors; Kainate receptors; GluK1; GluK3; Phenylalanine;
Keywords: گیرنده های گلوتامات یوناتروپیک; CON; control; DAG; diacylglycerol; GD; gestational day; HIP; hippocampus; iGluRs; ionotropic glutamate receptors; LTD; long-term depression; LTP; long-term potentiation; MB; mammillary body; mGluRs; metabotropic glutamate receptors; MWM; Morris water maze
Keywords: گیرنده های گلوتامات یوناتروپیک; BSA; bovine serum albumin; DAPI; 4â²,6-diamidino-2-phenylindole; DRG; dorsal root ganglia; GLS; glutaminase; HRP; horseradish peroxidase; ICG; intrinsic cardiac ganglia; iGluRs; ionotropic glutamate receptors; MGI; mean gray intensity; mGluRs; metabotrop
Keywords: گیرنده های گلوتامات یوناتروپیک; ionotropic glutamate receptors; structural biology; pharmacology
Keywords: گیرنده های گلوتامات یوناتروپیک; AD; amygdala; ANOVA; analysis of variance; CMS; chronic mild stress; FST; forced swimming test; GD; gestational day; GluR; glutamate receptor; HIP; hippocampus; iGluRs; ionotropic glutamate receptors; mGluRs; metabotropic glutamate receptors; NMDA; N-meth
Keywords: گیرنده های گلوتامات یوناتروپیک; BCA; bicinchoninic acid; EPM; elevated plus maze; GD; gestational day; iGluRs; ionotropic glutamate receptors; LSD; least significant difference; mGluRs; metabotropic glutamate receptors; PCMS; prenatal chronic mild stress; PKC; protein kinase C; PND; pos
Keywords: گیرنده های گلوتامات یوناتروپیک; l-Glutamic acid; Ionotropic glutamate receptors; Excitatory amino acid transporters; Pyrazoline
Keywords: گیرنده های گلوتامات یوناتروپیک; ANOVA; analysis of variance; GABA; γ-aminobutyric acid; SEM; standard error of the mean; NMDA; N-methyl-d-aspartate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; iGluRs; ionotropic glutamate receptors; mGluRs; metabotropic glutamate recep
Keywords: گیرنده های گلوتامات یوناتروپیک; Ionotropic glutamate receptors; Kaitocephalin; Natural product; NMDA receptors; Structure–activity relationship study
Extracellular Application of CRMP2 Increases Cytoplasmic Calcium through NMDA Receptors
Keywords: گیرنده های گلوتامات یوناتروپیک; [Ca2+]i; intracellular calcium concentration; AP-5; (2R)-amino-5-phosphonovaleric acid; CBD3; calcium channel binding domain 3; CM; conditioned media; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; CRMP2; Collapsin Response Mediator Protein 2; FBS; fetal bov
Inhibition of the NMDA and AMPA receptor channels by antidepressants and antipsychotics
Keywords: گیرنده های گلوتامات یوناتروپیک; Ionotropic glutamate receptors; Antidepressants; Patch-clamp; Inhibition; Mechanisms; Neuropathic pain;
Pharmacological characterization and binding modes of novel racemic and optically active phenylalanine-based antagonists of AMPA receptors
Keywords: گیرنده های گلوتامات یوناتروپیک; Ionotropic glutamate receptors; AMPA; GluA2; Phenylalanine; Competitive antagonist; Chiral resolution; Molecular modeling;
Radiosynthesis and preliminary PET evaluation of 18F-labeled 2-(1-(3-fluorophenyl)-2-oxo-5-(pyrimidin-2-yl)-1,2-dihydropyridin-3-yl)benzonitrile for imaging AMPA receptors
Keywords: گیرنده های گلوتامات یوناتروپیک; mGluRs; metabotropic glutamate receptors; iGluRs; ionotropic glutamate receptors; NMDA; N-methyl-d-aspartate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; PET; positron emission tomography; CNS; central nervous system; TEA[18F]; [18F]tetra
γ-Glutamyl-dipeptides: Easy tools to rapidly probe the stereoelectronic properties of the ionotropic glutamate receptor binding pocket
Keywords: گیرنده های گلوتامات یوناتروپیک; Glutamic acid; Dipeptides; Ionotropic glutamate receptors; Flow-chemistry; Polymer-supported reagents;
Arctigenin reduces neuronal responses in the somatosensory cortex via the inhibition of non-NMDA glutamate receptors
Keywords: گیرنده های گلوتامات یوناتروپیک; Arctigenin; Ionotropic glutamate receptors; Evoked field potentials; Rat; Brain slices; In vivo experimentsAMPA, α-amino-3-hydroxy-5-methylisoxazole-4-propionate; NMDA, N-methyl-D-aspartate; S.E.M., standard error of means
NBQX, a highly selective competitive antagonist of AMPA and KA ionotropic glutamate receptors, increases seizures and mortality following picornavirus infection
Keywords: گیرنده های گلوتامات یوناتروپیک; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole-propionate; ANOVA; Analysis of variance; ASDs; anti-seizure drugs; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; CNS; central nervous system; DA; Daniels; GABA; γ-aminobutyric acid; GFAP; glial fibrillary acidi
Central mechanism of the cardiovascular responses caused by L-proline microinjected into the paraventricular nucleus of the hypothalamus in unanesthetized rats
Keywords: گیرنده های گلوتامات یوناتروپیک; L-Proline; Paraventricular nucleus of the hypothalamus (PVN); Cardiovascular response; Ionotropic glutamate receptors; Oxide nitric
Emerging novel roles of neuropeptide Y in the retina: From neuromodulation to neuroprotection
Keywords: گیرنده های گلوتامات یوناتروپیک; BrdU; 5-bromo-2â²-deoxyuridine; [Ca2+]i; intracellular calcium; CNS; central nervous system; DPP-IV; dipeptidyl peptidase IV; E18; embrionic day 18; ERK; extracellular signal-regulated kinases; GABA; γ-aminobutyric acid; GAD 65; glutamic acid decarboxyl
Modal gating of GluN1/GluN2D NMDA receptors
Keywords: گیرنده های گلوتامات یوناتروپیک; Ionotropic glutamate receptors; Electrophysiology; Single channel recordings; NR2D
Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors
Keywords: گیرنده های گلوتامات یوناتروپیک; AMPA; (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionate; CBG-IV; (2S,1â²R,2â²S)-2-(2â²-carboxycyclobutyl)glycine; CNS; central nervous system; iGluRs; ionotropic glutamate receptors; KA; kainate; LBD; ligand binding domain; NMDA; N-methyl-d-asp
3-Hydroxy-1H-quinazoline-2,4-dione derivatives as new antagonists at ionotropic glutamate receptors: Molecular modeling and pharmacological studies
Keywords: گیرنده های گلوتامات یوناتروپیک; Ionotropic glutamate receptors; 3-Hydroxyquinazoline-2,4-diones; AMPA receptor antagonists; Kainate receptor antagonists; Neuroprotective agents; Ligand-receptor modeling studies; Glu; glutamate; iGluRs; ionotropic glutamate receptors; NMDA; N-methyl-d-
Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate
Keywords: گیرنده های گلوتامات یوناتروپیک; AMPA; 2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid; ATD; amino-terminal domain; CTD; carboxy-terminal domain; iGluRs; ionotropic glutamate receptors; IPTG; isopropyl-β-d-thiogalactopyranoside; KARs; kainate receptors; LBD; ligand binding dom
Differences in glutamate-mediated calcium responses in the ventral cochlear nucleus and inferior colliculus of the developing rat
Keywords: گیرنده های گلوتامات یوناتروپیک; ACSF; artificial cerebrospinal fluid; [Ca2+]i; free intracellular calcium concentration; CIC; central nucleus of the inferior colliculus; CN; cochlear nucleus; CNS; central nervous system; CHPG; (RS)-2-Chloro-5-hydroxyphenylglycine; DCN; dorsal cochlear n
Sensitization of rat facial cutaneous mechanoreceptors by activation of peripheral N-methyl-d-aspartate receptors
Keywords: گیرنده های گلوتامات یوناتروپیک; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ANOVA; Analysis of variance; APV; 2-amino-5-phosphonovalerate; CGRP; Calcitonin gene-related peptide; CV; Conduction velocity; CY3; Cyanine; EC50; Half maximal effective concentration; ELISA; En
Pharmacology of ionotropic glutamate receptors: A structural perspective
Keywords: گیرنده های گلوتامات یوناتروپیک; Ionotropic glutamate receptors; AMPA receptors; Kainate receptors; NMDA receptors; Neurotransmitter; Clamshell; Agonist; Antagonist; Receptor desensitization
Inhibitory effects of Group I metabotropic glutamate receptors antagonists on the expression of NMDA receptor NR1 subunit in morphine tolerant rats
Keywords: گیرنده های گلوتامات یوناتروپیک; CNS; central nervous system; iGluRs; ionotropic glutamate receptors; NMDAR; N-methyl-d-aspartic acid receptor; NR1; NMDA-R1 subunit; mGluRs; metabotropic glutamate receptors; mGluR1; mGlu receptor subtype 1; mGluR5; mGlu receptor subtype 5; AIDA; (RS)-1-A
Characterization of ionotropic glutamate receptors in insect neuro-muscular junction
Keywords: گیرنده های گلوتامات یوناتروپیک; Calliphora vicina; Ionotropic glutamate receptors; AMPA receptors
Role of excitatory amino acids in the mediation of tracheobronchial cough induced by citric acid inhalation in the rabbit
Keywords: گیرنده های گلوتامات یوناتروپیک; Airway defensive reflexes; Ionotropic glutamate receptors; Nucleus tractus solitarii; Caudal ventral respiratory group; Sneeze
Microtransplantation of ligand-gated receptor-channels from fresh or frozen nervous tissue into Xenopus oocytes: A potent tool for expanding functional information
Keywords: گیرنده های گلوتامات یوناتروپیک; TLE; temporal lobe epilepsy; nAChRs; nicotinic acetylcholine receptors; GluRs; ionotropic glutamate receptors; GABAA; γ-aminobutyric acid type A; CTLE; childhood temporal lobe epilepsy; CD; cortical dysplasia; BDNF; brain-derived neurotrophic factor; AD;
The history of the pharmacology and cloning of ionotropic glutamate receptors and the development of idiosyncratic nomenclature
Keywords: گیرنده های گلوتامات یوناتروپیک; Ionotropic glutamate receptors; NMDA receptors; AMPA receptors; Kainate receptors; History; Nomenclature;
Diabetes changes ionotropic glutamate receptor subunit expression level in the human retina
Keywords: گیرنده های گلوتامات یوناتروپیک; Diabetes; Human; Diabetic retinopathy; Ionotropic glutamate receptors
GABAA and strychnine-sensitive glycine receptors modulate N-methyl-d-aspartate-evoked acetylcholine release from rat spinal motoneurons: A possible role in neuroprotection
Keywords: گیرنده های گلوتامات یوناتروپیک; primary cultures; ALS; radiolabeled neurotransmitter; calcium channels; NMDA receptor subunit; ACh; acetylcholine; ACM; astrocyte-conditioned medium; ALS; amyotrophic lateral sclerosis; ANOVA; analysis of variance; DMEM; Dulbecco's modified Eagle's medium
NMDA and non-NMDA receptor-mediated differential Ca2+ load and greater vulnerability of motor neurons in spinal cord cultures
Keywords: گیرنده های گلوتامات یوناتروپیک; NMDA; N-methyl-d-aspartate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA); APV; α-2-amino-5-phosphonopentanoic acid; NBQX; 2-3 dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline; CCCP; carbonyl cyanide m-chlorophenyl hydrazone; EMEM;
Novel AMPA and kainate receptor antagonists containing the pyrazolo[1,5-c]quinazoline ring system: Synthesis and structure-activity relationships
Keywords: گیرنده های گلوتامات یوناتروپیک; Ionotropic glutamate receptors; AMPA receptor antagonists; KA receptor antagonists; Pyrazolo[1,5-c]quinazolines;
Cardiovascular function of a glutamatergic projection from the hypothalamic paraventricular nucleus to the nucleus tractus solitarius in the rat
Keywords: گیرنده های گلوتامات یوناتروپیک; blood pressure; barodenervation; ionotropic glutamate receptors; microinjections; sympathetic nerve activity; VGLUT2aCSF, artificial cerebrospinal fluid; AN, aortic nerve; BDA, biotinylated dextran amine; BP, blood pressure; bpm, beats/min; CVLM, caudal v
Tricyclic antidepressants, but not the selective serotonin reuptake inhibitor fluoxetine, bind to the S1S2 domain of AMPA receptors
Keywords: گیرنده های گلوتامات یوناتروپیک; Tricyclic antidepressants; Ionotropic glutamate receptors; AMPA; Fluoxetine; S1S2; Selective serotonin reuptake inhibitor
Synthesis and pharmacological characterization at glutamate receptors of erythro- and threo-tricholomic acid and homologues thereof
Keywords: گیرنده های گلوتامات یوناتروپیک; Tricholomic acid; Ionotropic glutamate receptors; Metabotropic glutamate receptors; 1,3-Dipolar cycloaddition;
The role of excitatory amino acids and substance P in the mediation of the cough reflex within the nucleus tractus solitarii of the rabbit
Keywords: گیرنده های گلوتامات یوناتروپیک; Respiratory reflexes; Ionotropic glutamate receptors; Control of breathing; Abdominal muscles; Central sensitization
Immunocytochemical and pharmacological characterization of metabotropic glutamate receptors of the vestibular end organs in the frog
Keywords: گیرنده های گلوتامات یوناتروپیک; mGluR; metabotropic glutamate receptors; iGluR; ionotropic glutamate receptors; SCC; semicircular canals; mGluR1α; group I metabotropic glutamate receptors; mGluR2/3; group II metabotropic glutamate receptors; ACPD; (1S,3R)-1-aminocyclopentane-trans-1,3-
Mechanical loading modulates glutamate receptor subunit expression in bone
Keywords: گیرنده های گلوتامات یوناتروپیک; Ionotropic glutamate receptors; Mechanical load; Osteoclast; Bone lining Cells; Immunohistochemistry; Rat;
1-Substituted pyrazolo[1,5-c]quinazolines as novel Gly/NMDA receptor antagonists: Synthesis, biological evaluation, and molecular modeling study
Keywords: گیرنده های گلوتامات یوناتروپیک; Ionotropic glutamate receptors; Gly/NMDA receptor antagonists; AMPA receptor antagonists; Pyrazoloquinazoline derivatives
Ionotropic glutamate receptors and glutamate transporters are involved in necrotic neuronal cell death induced by oxygen-glucose deprivation of hippocampal slice cultures
Keywords: گیرنده های گلوتامات یوناتروپیک; neuroprotection; neurodegeneration; cerebral ischemia; GLT-1; GLAST; GDNF; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CNQX; 6-cyano-7-nitroquinoxaline-2,3-(1H,4H)-dione; dl-TBOA; dl-threo-beta-benzyloxyaspartate; FJ-B; Fluoro-Jade B; GDN