Keywords: PEG; polyethylene glycol; RGD; arginine-glycine-aspartic acid; PBS; phosphate buffer saline; FITC; fluoresceine isothiocyanate; BSA; bovine serum albumin; hFFs; human foreskin fibroblasts; TCPS; tissue culture polystyrene; mPER; mammalian protein extracti
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Identification and application of self-binding zipper-like sequences in SARS-CoV spike protein
Keywords: S; Spike protein; HR; Heptad repeat; HIV-1; Human immunodeficiency virus type I; SARS-CoV; Severe acute respiratory syndrome associated coronavirus; RBD; Receptor binding domain; FP; Fusion peptide; 6-HB; Six-helix bundle; MPER; Membrane proximal external
Exposure of the HIV-1 broadly neutralizing antibody 10E8 MPER epitope on the membrane surface by gp41 transmembrane domain scaffolds
Keywords: MPER; membrane-proximal external region; TMD; transmembrane domain; Env; HIV-1 envelope glycoprotein; MD; molecular dynamics; bNAb; broadly neutralizing antibody; CDR-H3; complementarity-determining region three of the heavy chain; HC; heavy chain; WT; wi
Development of a DNA vaccine expressing a secreted HIV-1 gp41 ectodomain that includes the membrane-proximal external region
Keywords: MPER; membrane proximal external region; FP; fusion peptide; bnAb; broadly neutralizing antibody; HIV-1; DNA vaccine; gp41; Membrane-proximal external region; Broadly neutralizing antibodies;
Functional Contacts between MPER and the Anti-HIV-1 Broadly Neutralizing Antibody 4E10 Extend into the Core of the Membrane
Keywords: MPER; membrane-proximal external region; bNAb; broadly neutralizing antibody; CDRH3; complementarity-determining region three of the heavy chain; TMD; transmembrane domain; VL; virus-like; WT; wild-type; PsV; pseudovirus particle; NBD; 4-chloro-7-nitroben
Evaluation of a novel multi-immunogen vaccine strategy for targeting 4E10/10E8 neutralizing epitopes on HIV-1 gp41 membrane proximal external region
Keywords: HIV-1; Vaccine; gp41; MPER; Rabbit; Neutralizing antibody; Antibody maturation; Next-generation sequencing; NGS;
Modulating immunogenic properties of HIV-1 gp41 membrane-proximal external region by destabilizing six-helix bundle structure
Keywords: HIV-1; gp41; MPER; Fusion intermediate;
Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection
Keywords: ADCC; Antibody-dependent cell-mediated cytotoxicity; ARV; Anti-retroviral; AZT; Zidovudine; bnAb; Broadly neutralizing antibody; CD4bs; CD4 binding site; dIgA; Dimeric IgA; FcRn; Neonatal Fc receptor; GalCer; Galactosyl ceramide; GI; Gastrointestinal; GU;
Definition of an 18-mer Synthetic Peptide Derived from the GB virus C E1 Protein as a New HIV-1 Entry Inhibitor
Keywords: Acm; acetamidomethyl; ACN; acetonitrile; Dbz; diaminobenzoyl; DHB; 2,5-dihydroxybenzoic acid; DIPEA; diisopropylethylamine; FP; fusion peptide; GBV-C; GB virus C; HAART; highly active antiretroviral therapy; HATU; 2-(1H-7-azabenzotriazole-1-yl)-1,1,3,3-te
Eliciting neutralizing antibodies against the membrane proximal external region of HIV-1 Env by chimeric live attenuated influenza A virus vaccines
Keywords: MPER; Attenuated influenza A virus; HA; HIV-1 vaccine;
Liposomal vaccines incorporating molecular adjuvants and intrastructural T-cell help promote the immunogenicity of HIV membrane-proximal external region peptides
Keywords: Liposome; Adjuvant; HIV vaccine; Lipid membrane; MPER; Nanoparticle;
Elicitation of HIV-1 neutralizing antibodies by presentation of 4E10 and 10E8 epitopes on Norovirus P particles
Keywords: Broadly neutralizing antibody; MPER; Norovirus P particle; HIV-1 vaccine;
Immunogenic properties of a trimeric gp41-based immunogen containing an exposed membrane-proximal external region
Keywords: HIV-1; gp41; MPER; Vaccine; Immunogenicity; Rabbit;
Prime/boost immunization with HIV-1 MPER-V3 fusion construct enhances humoral and cellular immune responses
Keywords: Env; envelope; Gp; glycoprotein; bNAbs; broadly neutralizing antibodies; MPER; membrane-proximal external region; APCs; antigen presenting cells; CPPs; cell penetrating peptides; NLS; nuclear localization sequence; HIV; MPER-V3; DNA vaccine; Peptide vacci
Comparative mucosal immunogenicity of HIV gp41 membrane-proximal external region (MPER) containing single and multiple repeats of ELDKWA sequence with defensin peptides
Keywords: gp41; MPER; HIV; Defensins; IgG/IgA antibodies; Neutralization
Immunogen design for HIV-1 and influenza
Keywords: HIV-1; human immunodeficiency virus-1; Env; envelope; PNGS; potential N-linked glycosylation sites; bNAb; broadly neutralizing antibody; GL; germline; T/F; Transmitted/Founder virus; MPER; membrane proximal external region; OD; Outer domain; CD4bs; CD4 bi
Construction and characterisation of replicating foamy viral vectors expressing HIV-1 epitopes recognised by broadly neutralising antibodies
Keywords: FFV; feline foamy virus; HIV-1; human immunodeficiency virus-1; MPER; membrane proximal external region; FPPR; fusion peptide proximal region; HIV-1; Neutralising antibodies; Foamy viruses; MPER;
An anti-phosphoinositide-specific monoclonal antibody that neutralizes HIV-1 infection of human monocyte-derived macrophages
Keywords: Ab; Antibody; GalCer; Galactosyl ceramide; HIV-1; Human immunodeficiency virus type 1; M-CSF; Macrophage colony stimulating factor; MPER; Membrane proximal external region; mAb; Monoclonal antibody; MDM; Monocyte-derived macrophages; PBMCs; Peripheral blo
Destabilization exerted by peptides derived from the membrane-proximal external region of HIV-1 gp41 in lipid vesicles supporting fluid phase coexistence
Keywords: MPER; HIV gp41; Membrane fusion; Lytic pore; Lipid rafts; Lo-Ld coexistence;
Assessment of antibody responses against gp41 in HIV-1-infected patients using soluble gp41 fusion proteins and peptides derived from M group consensus envelope
Keywords: HIV-1; gp41; Neutralizing antibody; MPER
Correlative association between circadian expression of mousePer2 gene and the proliferation of the neural stem cells
Keywords: neural stem cell; proliferation; BrdU incorporation; circadian; mPer2; BrdU; bromodeoxyuridine; EGF; epidermal growth factor; mPer; mousePeriod; ODNs; oligonucleotides; PBS; phosphate-buffered saline; PBSGT; phosphate-buffered saline containing 0.1% Trito
Immunogenicity of recombinant human immunodeficiency virus type 1-like particles expressing gp41 derivatives in a pre-fusion state
Keywords: HIV; gp41; MPER; Immunogen; Immunodominance; Neutralizing antibody; 2F5; 4E10; Virus-like particle; Vaccine