Keywords: cutaneous T-cell lymphoma; hereditary nonpolyposis colon cancer; Lynch syndrome; microsatellite instability; MLH1; Muir-Torre syndrome; MSH2; mycosis fungoides; ECP; extracorporeal photopheresis; HNPCC; hereditary nonpolyposis colorectal carcinoma; ICL; i
مقالات ISI (ترجمه نشده)
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Keywords: MMR mutations; Lynch syndrome; Hispanics; MLH1; MSH2; MSH6; PMS2; colon cancer;
Keywords: Mismatch repair; Castration resistant prostate cancer; MLH1; MSH2; MSH6; PMS2;
Keywords: MMR; mismatch repair; MSI; microsatellite instability; PCNA; proliferating cellular nuclear antigen; RPA; replication protein A; RFC; replication factor C; EXO1; exonuclease 1; H3K36me3; histone H3 lysine 36 trimethylation; H3K36me3; Histone methylation;
Keywords: LS; Lynch syndrome; CRC; colorectal cancer; HNPCC; hereditary non-polyposis colon cancer; MMR; mismatch repair; FAP; familial adenomatous polyposis; CFS; cancer family syndrome; MSI; microsatellite instability; IDL; insertion/deletion loop; MSH2; human mu
Keywords: Bloom syndrome; dyskeratosis congenita; genetic testing; Gorlin syndrome; Muir-Torre syndrome; nonmelanoma skin cancer; oculocutaneous albinism; Rothmund-Thomson syndrome; Werner syndrome; 5-FU; 5-fluorouracil; ADA1; adenosine deaminase 1; ADA-SCID; a
Keywords: MMR; mismatch repair; MSH; mutS homolog; MLH; mutL homolog; BER; base excision repair; NER; nucleotide excision repair; TNR; trinucleotide repeat; DM1; myotonic dystrophy type 1; HD; huntington's disease; FRDA; Friedreich's ataxia; FXD; fragile X dise
Keywords: Lynch Syndrome; microsatellite instability; mismatch repair deficiency; MLH1; MSH2; MSH6; PMS2;
Keywords: colon cancer; endometrial cancer; hereditary cancer; Lynch syndrome; microsatellite instability; mismatch repair; MutS homolog 2; MutS homolog 6; sebaceous epithelioma; sebaceous neoplasm; urothelial cancer; BerEP4; anti epCam antibody; CK; cytokeratin; E
Keywords: Constitutional mismatch repair deficiency syndrome; MLH1; MSH2; PMS2; MSH6; Microsatellite instability
DNA damage response genes mark the early transition from colitis to neoplasia in colitis-associated colon cancer
Keywords: DDR; DNA Damage Response; IBD; Inflammatory Bowel Disease; CAC; Colitis-Associated Cancer; MSI; microsatellite instability; AOM; Azoxymethane; DSS; Dextran sodium sulfate; HMSL; high magnification surgical lenses; MVT; macroscopically visible tumor; NMVT;
DNA mismatch repair in cancer
Keywords: 5-FU; 5-fluorouracil; bMMRD; Biallelic mismatch repair deficiency; CD28; cluster of differentiation 28; CIN; Chromosomal instable; CR; complete response; CRC; colorectal cancer; CTL; cytotoxic T-lymphocytes; CTLA-4; cytotoxic T lymphocyte antigen-4; DFS;
Cell cycle arrest mediated by Cd-induced DNA damage in Arabidopsis root tips
Keywords: CDKs; Cyclin-dependent kinases; CYCB1;1; Cyclin B1;1; qRT-PCR; Real time quantitative reverse transcription-polymerase chain reaction; BRCA1; Breast cancer susceptibility1; PCNA; Proliferation cell nuclear antigen; DSB; Double strand break; GR1; Gamma res
Overexpression of MutL homolog 1 and MutS homolog 2 proteins have reversed prognostic implications for stage I-II colon cancer patients
Keywords: Colon cancer; MLH1; MSH2; CEA; Mismatch repair;
Recommendations on surveillance and management of biallelic mismatch repair deficiency (BMMRD) syndrome: a consensus statement by the US Multi-Society Task Force on Colorectal Cancer
Keywords: BMMRD; biallelic mismatch repair deficiency; CMMRD; constitutional mismatch repair deficiency; CRC; colorectal cancer; GRADE; Grades of Recommendation, Assessment, Development and Evaluation; LS; Lynch syndrome; MLH; Mut L homolog 1; MSH2; Mut S homolog 2
The polymorphisms of MSH6 gene are associated with AIDS progression in a northern Chinese population
Keywords: MSH6; MSH2; SNPs; HIV-1; AIDS; Progression;
Mouse models of DNA mismatch repair in cancer research
Keywords: Mouse models; DNA mismatch repair; Msh2; Mlh1; Hereditary non-polyposis colon cancer; Lynch syndrome;
Review: Clinical aspects of hereditary DNA Mismatch repair gene mutations
Keywords: Lynch syndrome; Constitutional Mismatch Repair Deficiency syndrome; clinic; DNA Mismatch repair; MLH1; MSH2; PMS2; MSH6; review;
Importance of universal mismatch repair protein immunohistochemistry in patients with sebaceous neoplasia as an initial screening tool for Muir-Torre syndrome
Keywords: Sebaceous neoplasia; Muir-Torre syndrome; MLH1; MSH2; MSH6; PMS2
SOX9 expression predicts relapse of stage II colon cancer patients
Keywords: dMMR; mismatch repair deficiency; IHC; immunohistochemistry; MLH1; MutL homolog 1; MMR; mismatch repair; MSH2; MutS protein homolog 2; MSH6; MutS homolog 6; MSI; microsatellite instability; pMMR; mismatch repair proficient; PMS2; postmeiotic segregation i
Absence of MutSβ leads to the formation of slipped-DNA for CTG/CAG contractions at primate replication forks
Keywords: Huntington’s disease; Trinucleotide repeats; Slippage; Repeat instability; Mismatch repair; MSH2; MSH3; Ligase I; PCNA; MutSbeta; Repeat expansions; Repeat contractions
Down-regulation of MSH2 expression by Hsp90 inhibition enhances cytotoxicity affected by tamoxifen in human lung cancer cells
Keywords: MSH2; AKT; Tamoxifen; Hsp90 inhibition; Non-small cell lung cancer;
MSH2 role in BRCA1-driven tumorigenesis: A preliminary study in yeast and in human tumors from BRCA1-VUS carriers
Keywords: BRCA1; MSH2; Hereditary breast and ovarian cancer; Yeast functional assay; Mutational analysisHBOC, hereditary breast and ovarian cancer; VUS, variants of unknown significance; MMR, mismatch repair; BASC complex, BRCA1-Associated Genome Surveillance Compl
A rare MSH2 mutation causes defective binding to hMSH6, normal hMSH2 staining, and loss of hMSH6 at advanced cancer stage
Keywords: Lynch syndrome; Mismatch repair; MSH2; MSH6; Second hit; Variants of unknown significance
MLH1 and MSH2 mutation screening in HNPCC families of Hungary – Two new MMR gene mutations
Keywords: Hereditary Non-Polyposis Colorectal Cancer; Bethesda criteria; Modified Amsterdam criteria; MLH1; MSH2
p53-Dependent suppression of genome instability in germ cells
Keywords: Medaka fish; Microsatellite instability; Radiation; Spermatogonial stem cell; msh2; p53CE, fluorescent capillary electrophoresis; DDR, DNA damage response; DSB, double-strand break; ESTR, expanded simple tandem repeat; HRM, high-resolution melting; MMR, m
Promoter hypermethylation of DNA repair genes MLH1 and MSH2 in adenocarcinomas and squamous cell carcinomas of the lung
Keywords: Adenocarcinoma; Squamous cell carcinoma; Lung; Hypermethylation; MLH1; MSH2Adenocarcinoma; Carcinoma das células escamosas; Pulmão; Hipermetilação; MLH1; MSH2
Single nucleotide polymorphism in hMLH1 promoter and risk of tobacco-related oral carcinoma in high-risk Asian Indians
Keywords: hMLH1; human MutL homolog 1; MMR; mismatch repair; SNP; single nucleotide polymorphism; OSCC; oral squamous cell carcinoma; PCR-RFLP; polymerase chain reaction-restriction fragment length polymorphism; BPDE; benzo(a)pyrene diol epoxide; DRC; DNA repair ca
Inhibition of p38 MAPK-dependent MutS homologue-2 (MSH2) expression by metformin enhances gefitinib-induced cytotoxicity in human squamous lung cancer cells
Keywords: Gefitinib; MSH2; p38 MAPK; Metformin; Non-small cell lung cancer; Cytotoxicity; Tyrosine kinase inhibitor;
Cisplatin upregulates MSH2 expression by reducing miR-21 to inhibit A549 cell growth
Keywords: microRNA; Lung cancer; MSH2; Cisplatin; Gene expression; miRNAs; microRNAs; MMR; mismatch repair; 3â²-UTR; 3â²-untranslated region; hMSH2; Human mutS homolog 2; hMLH1; human mutL homolog 1; nt; nucleotides; FACS; Flow cytometry; RT-PCR; Reverse transcri
Patients with Lynch Syndrome Mismatch Repair Gene Mutations Are at Higher Risk for Not Only Upper Tract Urothelial Cancer but Also Bladder Cancer
Keywords: Bladder cancer; Lynch syndrome; MSH2; Microsatellite instability; Mismatch repair; Genetic
PARP1 impact on DNA repair of platinum adducts: Preclinical and clinical read-outs
Keywords: ERCC1; MSH2; PARP1; Cisplatin; CDDP; Lung cancer; NSCLC biomarkers; Adjuvant chemotherapy; Immunohistochemistry; IALT-bio
DNA mismatch repair protein MSH2 dictates cellular survival in response to low dose radiation in endometrial carcinoma cells
Keywords: DNA mismatch repair; Ionizing radiation; Low dose; Hypersensitivity; Endometrial; MSH2; G2/M; Cell cycle arrest
Mouse DNA polymerase kappa has a functional role in the repair of DNA strand breaks
Keywords: Polymerase kappa; PCNA; MSH2; Strand break repair; Laser micro-irradiation
Esophageal Cancer Risk is Associated with Polymorphisms of DNA Repair Genes MSH2 and WRN in Chinese Population
Keywords: MSH2; WRN; Ku70; Single-nucleotide polymorphism; Esophageal cancer
Role of the Msh2 gene in genome maintenance and development in mouse fetuses
Keywords: DNA mismatch repair; Mutator phenotype; Mouse fetus; Developmental abnormality; Msh2; lacZ
MSH2 promoter hypermethylation in circulating tumor DNA is a valuable predictor of disease-free survival for patients with esophageal squamous cell carcinoma
Keywords: MSH2; Methylation; Real-time methylation-specific PCR (real-time MSP); Disease-free survival (DFS); Esophageal squamous cell carcinoma (ESCC)
The mismatch repair system protects against intergenerational GAA repeat instability in a Friedreich ataxia mouse model
Keywords: Friedreich ataxia; FRDA, frataxin; GAA trinucleotide repeat; Transgenic mouse model; Mismatch repair; MMR; Msh2; Msh3; Msh6; Pms2
Sebaceous neoplasms with mismatch repair protein expressions and the frequency of co-existing visceral tumors
Keywords: mismatch repair; Muir-Torre syndrome; sebaceous neoplasms; visceral malignancy; CEA; carcinoembryonic antigen; GI; gastrointestinal; GU; genitourinary; IHC; immunohistochemistry; MLH; mutL Homolog; MMR; mismatch repair; MSH2; mutS homolog 2; MSH6; mutS ho
Trypanosoma cruzi MSH2: Functional analyses on different parasite strains provide evidences for a role on the oxidative stress response
Keywords: Trypanosoma cruzi; DNA repair; MSH2; Oxidative stress; Trypanosoma brucei;
Voies de réparation de l'ADN et cancers bronchiques non à petites cellules : perspectives cliniques
Keywords: Réparation de l'ADN; cancer bronchique; CBNPC; altération des voies de réparation; biomarqueurs; ERCC1; MSH2; BRCA1; BRCA2; PARP; PARP1; DNA repair; lung cancer; NSCLC; DNA repair pathway deficiency; biomarkers; ERCC1; MSH2; BRCA1 BRCA2; PARP; PARP1;
Sublethal levels of cadmium down-regulate the gene expression of DNA mismatch recognition protein MutS homolog 6 (MSH6) in zebrafish (Danio rerio) embryos
Keywords: Cd, cadmium; hpf, hours post fertilization; MMR, DNA mismatch repair; MSH2, MutS homolog 2; MSH6, MutS homolog 6; PAGE, polyacrylamide gel electrophoresisCadmium; DNA mismatch repair; Embryo; MSH2; MSH6; Zebrafish
The effect of Msh2 knockdown on methylating agent induced toxicity in DNA glycosylase deficient cells
Keywords: Mismatch repair; Base excision repair; Msh2; Mpg; Nth1; Alkylating agents
DNA mismatch repair and the transition to hormone independence in breast and prostate cancer
Keywords: Mismatch repair; Prostate cancer; Breast cancer; Hormone independence; MSH2
DNA mismatch repair and the DNA damage response to ionizing radiation: Making sense of apparently conflicting data
Keywords: DNA mismatch repair; Ionizing radiation; Low dose; Hypersensitivity; MLH1; MSH2; RAD51; G2/M; Cell cycle arrest; Review
An Msh2 Conditional Knockout Mouse for Studying Intestinal Cancer and Testing Anticancer Agents
Keywords: Mismatch Repair; Msh2; Tumorigenesis; Chemotherapy; 5-FU; 5-fluorouracil; FOLFOX; 5-fluorouracil/leucovorin and oxaliplatin; MMR; mismatch repair; MSI; microsatellite instability; MSS; microsatellite stable; PCR; polymerase chain reaction;
Cancer genetics and reproduction
Keywords: hereditary cancer syndrome; ovarian cancer; endometrial cancer; BRCA1; BRCA2; MLH1; MSH2; hereditary non-polyposis colon cancer; lynch syndrome
Expresión de MLH1, MSH2 y MSH6 en oncocitomas y carcinomas de células cromófobas renales
Keywords: Oncocitoma renal; carcinoma de células cromófobas; MLH1; MSH2; MSH6Renal oncocytoma; chromophobe cell renal cell carcinoma; MLH1; MSH2; MSH6
Compromised repair of clustered DNA damage in the human acute lymphoblastic leukemia MSH2-deficient NALM-6 cells
Keywords: MSH2; Acute lymphoblastic leukemia (ALL); Clustered DNA lesions; DNA repair; Ionizing radiation;
Human MutL-complexes monitor homologous recombination independently of mismatch repair
Keywords: ATM; ATR; BLM; DNA double-strand break repair; MLH1; MSH2