Chemical synthesis, pharmacological evaluation and in silico analysis of new 2,3,3a,4,5,6-hexahydrocyclopenta[c]pyrazole derivatives as potential anti-mitotic agents
Keywords: MT، میکروتوبول; EDG, electron donating group; EWG, electron withdrawing groups; MT, microtubule; SAR, structure activity relationshipHexahydropyrazole; Anti-mitotic; Tubulin; Docking; Tubulin binding assay; Colchicine-binding assay