دانلود مقالات ISI درباره Mtorc1, Mtor Complex 1 + ترجمه فارسی

O-GlcNAcylation in Cancer Biology: Linking Metabolism and Signaling

Keywords: PI3K, phosphatidylinositol-3-kinase; AKT, protein kinase B; mTOR, mechanistic target of rapamycin; RTK, receptor tyrosine kinase; mTORC1, mTOR complex 1; SREBP-1, sterol regulatory element-binding protein 1; HIF-1α, hypoxia-inducible factor 1-alpha; LKB1,

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Differential regulation of Tregs and Th17/Th1 cells by a sirolimus-based regimen might be dependent on STAT-signaling in renal transplant recipients

Keywords: mTOR, mammalian target of rapamycin; MMF, mycophenolate mofetil; CNI, calcineurin inhibitor; SRL, sirolimus; TAC, tacrolimus; STAT, signal transducer and activator of transcription; mTORC1, mTOR complex 1; mTORC2, mTOR complex 2Calcineurin inhibitors; Reg

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Targeted deletion of Tsc1 causes fatal cardiomyocyte hyperplasia independently of afterload

Keywords: TSC, tuberous sclerosis complex; mTOR, mammalian target of rapamycin; mTORC1, mTOR complex 1; Rheb, ras homolog enriched in brain; S6K, p70S6 kinase; 4E-BP1, eukaryotic translation-initiation factor 4E-binding protein 1; AMPK, AMP-activated kinase; SMA, s

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Autophagy Modulation As a Potential Therapeutic Target for Liver Diseases

Keywords: autophagy; autophagosome; liver diseasesULK1, Uncoordinated 51-like kinase 1; mTORC1, mTOR complex 1; ER, endoplasmic reticulum; mTORC2, mTOR complex 2; NASH, Non Alcoholic Steato-Hepatitis; TG, triglyceride; HSC, hepatic stellate cells; STEBPs, sterol re

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Cap-dependent translation initiation factor, eIF4E, is the target for Ouabain-mediated inhibition of HIF-1α

Keywords: eIF4E, eukaryotic initiation factor 4E; eIF4G, eukaryotic initiation factor 4G; eIF2α, eukaryotic initiation factor 2α; HIF-1, hypoxia-inducible factor 1; mTORC1, mTOR complex 1; NLS, nuclear localization signal; GFP, green fluorescent protein; Rluc, reni

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2, and PTK6 as sensitizing targets of rapamycin activity

Keywords: RNAi, RNA interference; HDAC, Histone deacetylase; HDACi, Histone deacetylase inhibitor; mTOR, mechanistic target of rapamycin; mTORC1, mTOR complex 1; mTORC2, mTOR complex 2; LOF, loss-of-function; TRNBC, triple negative breast cancer; RSP6, ribosomal S6

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Mechanistic target of rapamycin in common carp: cDNA cloning, characterization, and tissue expression

Keywords: mTOR, mechanistic target of rapamycin; mTORC1, mTOR complex 1; mTORC2, mTOR complex 2; TOP, terminal oligopyrimidine; FKBP12, FK506 binding proteins 12; ORF, open reading frame; EB, ethidium bromide; PCR, polymerase chain reaction; ANOVA, one-way analysis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Phosphorylation of 4E-BP1 predicts sensitivity to everolimus in gastric cancer cells

Keywords: 4E-BP1, 4E-binding protein 1; DCR, disease control rate; mTOR, mammalian target of rapamycin; mTORC1, mTOR complex 1; mTORC2, mTOR complex 2; PFS, progression-free survival; PI3K, phosphoinositide 3-kinase; S6K1, S6 kinase 1mTOR inhibitor; Gastric cancer;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Co-administration of perifosine with paclitaxel synergistically induces apoptosis in ovarian cancer cells: More than just AKT inhibition

Keywords: mTORC1, mTOR complex 1; AMPK, AMP-activated protein kinase; AICAR, 5-Aminoimidazole-4-carboxamide ribotide; JNK, c-Jun N-terminal kinases; ERK, extracellular signal-regulated kinase; ROS, reactive oxygen species; HDACi, histone deacetylase inhibitor; ACC,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

mTOR regulation of autophagy

Keywords: mTOR, mammalian target of rapamycin; mTORC1, mTOR complex 1; mTORC2, mTOR complex 2; raptor, regulatory associated protein of mTOR; rictor, rapamycin insensitive companion of mTOR; Atg, Autophagy-related gene; TSC, tuberous sclerosis complex; Rheb, ras ho

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Activation of the mammalian target of rapamycin complex 1 is both necessary and sufficient to stimulate eukaryotic initiation factor 2Bɛ mRNA translation and protein synthesis

Keywords: eIF, eukaryotic initiation factor; Met-tRNAi, initiator methionyl-tRNA; GEF, guanine nucleotide exchange factor; mTOR, mammalian target of rapamycin; mTORC1, mTOR complex 1; Raptor, regulatory associated protein of mTOR; GβL, G protein β-subunit-like prot

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه