دانلود مقالات ISI درباره MTX، متوترکسات + ترجمه فارسی

ارزیابی مسیرهای چندگانه برای پیشگیری از اثربخشی ضد آتروژن از مواد مخدر هدف ماکروفاژها در پلاکهای آترواسکلروز

Multiple pathway assessment to predict anti-atherogenic efficacy of drugs targeting macrophages in atherosclerotic plaques

Keywords: MTX، متوترکسات; Pred, prednisolone; MTX, methotrexate; T09, T091317; Ptero, pterostilbene; 6-MP, mercaptopurine; Simva, simvastatin; Rapa, rapamycin; LXR, liver receptor X; CIRT, cardiovascular inflammation reduction trial; rHDL, recombinant high-density lipoprotein; ER,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

سینامات انولین به عنوان وسیله ای برای تحویل داروهای کولون

Cinnamate of inulin as a vehicle for delivery of colonic drugs

Keywords: MTX، متوترکسات; FSCN, cinnamoylated fructose; DHFR, dihydrofolate reductase; INCN, cinnamoylated inulin; MTX, methotrexate; TLC, thin layer chromatography; XTT, 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilideInulin; Cinnamoylated inulin; Inulinase

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

اثربخشی لیپوزومهای چند منظوره شامل داونوروبیسین و امتین برای درمان لوسمی حاد میلوئید

Efficacy of multi-functional liposomes containing daunorubicin and emetine for treatment of acute myeloid leukaemia

Keywords: MTX، متوترکسات; AML, Acute myeloid leukaemia; DDS, Drug delivery system; DNR, Daunorubicin; DOX, Doxorubicin; Eme, Emetine; FA, Folate; FR2, Folic acid receptor 2 (β); HEPC, Hydrogenated egg phosphatidylcholine; MTX, Methotrexate; PE, Phosphatidylethanolamine; PEG, Polye

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

سلول های بنیادی بیضه پس از درمان متوترکسات پتانسیل بازسازی خود را حفظ می کنند

Adipose-derived stem cells retain their regenerative potential after methotrexate treatment

Keywords: MTX، متوترکسات; ASC, adipose-derived stem cell; BMSC, bone marrow-derived stem cell; MTX, methotrexate; CY, cytarabine; ETO, etoposide; VIN, vincristine; SVF, stromal vascular fraction; PBS, phosphate buffered saline; ORO, Oil Red O; ARS, Alizarin Red S; sGAG, sulfated g

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

سندرم گیلن باره بعد از پیوند مغز استخوان آلوژنیک: گزارش موردی و بررسی متون

Guillain–Barré syndrome after allogeneic bone marrow transplantation: Case report and literature review

Keywords: MTX، متوترکسات; Ara-C, cytarabine; BU, busulfan; HDAC, high-dose cytarabine; IDA, idarubicin; MTX, methotrexate; PSL, prednisoloneAcute inflammatory demyelinating polyneuropathy; Allogeneic bone marrow transplantation; Guillain–Barré syndrome; Intravenous immunoglobulin

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

پیامد بارداری پس از tocilizumab تراپی در اوایل بارداری، مجموعه ای از مورد از مرکز داروشناسی Embryotox آلمان

Pregnancy outcome after tocilizumab therapy in early pregnancy-a case series from the German Embryotox Pharmacovigilance Center

Keywords: MTX، متوترکسات; Pregnancy outcome; Spontaneous abortion; Tocilizumab; Rheumatoid arthritis; Birth defects; Biologic disease-modifying antirheumatic drugsTCZ, tocilizumab; Mab, monoclonal antibody; IL-6, interleukin-6-receptor; RA, rheumatoid arthritis; MTX, methotrexate;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

متوتروکسات پاسخ Th-1 با سرکوب کاسپاز 1 و سیتوکین ها در بیماران مبتلا به پسوریازیس را تنظیم می کند

Methotrexate regulates Th-1 response by suppressing caspase-1 and cytokines in psoriasis patients

Keywords: MTX، متوترکسات; MTX, methotrexate; IL-18, interleukin-18; TNF-α, tumor necrosis factor alpha; IFN-γ, interferon gammaPsoriasis; Methotrexate; Interleukin-18; Caspase-1; Th-1 immune cells

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Second Line Chemotherapy for Advanced and Metastatic Urothelial Carcinoma: Vinflunine and Beyond—A Comprehensive Review of the Current Literature

Keywords: MTX، متوترکسات; urinary bladder; urothelium; carcinoma; drug therapy; salvage therapyBSC, best supportive care; CR, complete response; EGFR, epidermal growth factor receptor; GC, gemcitabine and cisplatin; Her, human epidermal growth factor receptor; MTX, methotrexate; M

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Targeting and liposomal drug delivery to CD40L expressing T cells for treatment of autoimmune diseases

Keywords: MTX، متوترکسات; hCD40L, human CD40L; TEM, transmission electron microscopy; PEG, polyethylene glycol; MTX, methotrexate; PDI, polydispersity index; TPA, phorbol ester 12-O-tetradec-anoylphorbol-13-acetate; EAE, experimental autoimmune encephalomyelitis; mCD40L, mouse CD4

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Quantum dots loaded nanogels for low cytotoxicity, pH-sensitive fluorescence, cell imaging and drug delivery

Keywords: MTX، متوترکسات; QDs, quantum dots; NGs, nanogels; QDs-NGs, quantum dots loaded nanogels; MTX, methotrexate; PLQY, photoluminescence quantum yields; MTX-QDs-NGs, methotrexate loaded QDs-NGs; Ly, lysozyme; CMC, carboxymethylcellulose; TGA, thioglycolic acid; DMEM, Dulbecco

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA-223 and miR-143 are important systemic biomarkers for disease activity in psoriasis

Keywords: MTX، متوترکسات; AUC, Area under the curve; FCH, Fold change; FDR, False discovery rate; hs-CRP, High sensitive C-reactive protein; MTX, Methotrexate; MV, Micro-vesicles; PASI, Psoriasis area and severity index; PBMCs, Peripheral blood mononuclear cells; PBS, Phosphate-bu

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Carbon nanoparticle from a natural source fabricated for folate receptor targeting, imaging and drug delivery application in A549 lung cancer cells

Keywords: MTX، متوترکسات; CNP, carbon nanoparticles; Mtx, methotrexate; Asp, asparaginase; FITC, fluorescein isothiocyanate; DHRF, dihydrofolate reductase; NCCS, National Centre for Cell Science; FA, folic acid; DMEM, Dulbecco’s minimal eagles medium; FTIR, Fourier transform infra

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Dioscin enhances methotrexate absorption by down-regulating MDR1 in vitro and in vivo

Keywords: MTX، متوترکسات; ABC, ATP-binding cassette; Caco-2 cells, human colon adenocarcinoma cells; MDR, multidrug resistance; MDR1, multidrug resistance 1; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; MTX, methotrexate; ADR, adriamycin; Ver, verapamil; Rif,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Biomarkers for methotrexate-induced liver injury: Urinary protein profiling of psoriasis patients

Keywords: MTX، متوترکسات; ALT, alanine aminotransferase; ESI, electrospray ionization; ITIH4, inter-alpha-trypsin inhibitor heavy chain H4; MALDI-TOF MS, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry; MTX, methotrexate; PASI, psoriasis area and sever

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Noni increased the systemic exposure of methotrexate in rats through inhibition on multi-drug resistance protein 2 (MRP 2) and breast cancer resistance protein (BCRP)

Keywords: MTX، متوترکسات; MTX, methotrexate; MRPs, multi-drug resistance proteins; BCRP, breast cancer resistance protein; NSAIDs, non-steroidal anti-inflammatory drugs; HPLC, high-performance liquid chromatography; Cmax, the peak blood concentration; AUC0-t, the areas under the c

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

The isolation of CHO cells with a site conferring a high and reproducible transgene amplification rate

Keywords: MTX، متوترکسات; Fluctuation analysis; Gene amplification; Recombinant protein; CHO cells; DG44; dhfrCHO, Chinese hamster ovary; DHFR, dihydrofolate reductase; MTX, methotrexate; ADA, adenosine deaminase; dCF, deoxycoformycin; SEAP, secreted embryonic alkaline phosphatase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Reduced absorption of long-chain fatty acids during methotrexate-induced gastrointestinal mucositis in the rat

Keywords: MTX، متوترکسات; Gastrointestinal mucositis; Long-chain fatty acids; Nutrient absorption; Liver fatty acid appearance; Chemotherapy; CitrullineGC–MS, gas chromatography–mass spectrometry; LCFA, long-chain fatty acids; MPO, myeloperoxidase; MTX, methotrexate; PFA, paraform

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Hypoxia influences stem cell-like properties in multidrug resistant K562 leukemic cells

Keywords: MTX، متوترکسات; AML, Acute myeloid leukemia; ABC, ATP-Binding Cassette; BM, bone marrow; DMSO, dimethyl sulfoxide; IC50, Drug concentrations inhibiting cell growth by 50%; DOX, doxorubicin; Ara-C, cytosine arabinoside; MTX, methotrexate; VCR, vincristine; MDR, multi-drug

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Pretreatment with valproic acid, a histone deacetylase inhibitor, enhances the sensitivity of the peripheral blood micronucleus assay in rodents

Keywords: MTX، متوترکسات; ALC, alcohol; AZT, zidovudine; CP, cyclophosphamide; ERT, erythrocytes; HDAC, histone deacetylase; MN, micronucleus; MNERT, micronucleated erythrocytes; MNRET, micronucleated reticulocytes; MTX, methotrexate; PB, peripheral blood; PBMN, peripheral blood m

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibition of integrins αv/α5-dependent functions in melanoma cells by an ECD-disintegrin acurhagin-C

Keywords: MTX، متوترکسات; ECD, Glu–Cys–Asp; ECM, extracellular matrix; FITC, fluorescein isothiocyanate; HUVECs, human umbilical vein endothelial cells; MFI, mean fluorescence intensity; MTT, 3-[4, 5-dimethylthiazol-2-yl]-2, 5-diphenyl tetrazolium bromide; MTX, methotrexate; PE, p

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Association of 25-hydroxyvitamin D serum levels and metabolic parameters in psoriatic patients with and without arthritis

Keywords: MTX، متوترکسات; glucose; lipids; psoriasis; psoriatic arthritis; vitamin DBMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MTX, methotrexate; TNF, tumor necrosis factor; 25-(OH)D, 25-hydroxyvitamin D

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of novel small compounds that restore E-cadherin expression and inhibit tumor cell motility and invasiveness

Keywords: MTX، متوترکسات; MTX, methotrexate; EMT, epithelial–mesenchymal transition; FBS, fetal bovine serumColorectal cancer; Melanoma; Compound; Small molecule screen; E-cadherin; Methotrexate

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

A long-term follow-up study of methotrexate in juvenile localized scleroderma (morphea)

Keywords: MTX، متوترکسات; localized scleroderma; methotrexate; morphea; outcome; prednisone; safety; thermographyCR, clinical remission; CRM, clinical remission on medication; CSS, computerized skin score; JLS, juvenile localized scleroderma; MTX, methotrexate; SSR, skin score rat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Transdermal delivery of the anti-rheumatic agent methotrexate using a solid-in-oil nanocarrier

Keywords: MTX، متوترکسات; MTX, methotrexate; l-Arg, l-Arginine; l-Lys, l-Lysine; IPM, isopropyl myristate; F-Na, fluorescein sodium salt; PBS, phosphate buffered saline solution; YMP, Yucatan micropig; TDDS, transdermal drug delivery system; S, solid complexes, solid phase; O, oil

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Comparative study between the effect of methotrexate and valproic acid on solid Ehrlich tumour

Keywords: MTX، متوترکسات; SEC, solid Ehrlich carcinoma; MTX, methotrexate; VPA, valproic acid; CAT, catalase; GR, glutathione reductase; MDA, malondialdehyde; TNF-α, tumour necrosis factor alphaMethotrexate; Valproic; Ehrlich; Mice

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

A liquid chromatography–tandem mass spectrometry (LC–MS/MS) method for monitoring drug exposure in hematopoietic stem cell transplant recipients

Keywords: MTX، متوترکسات; Chromatography; Mass spectrometry; Calcineurin inhibitor; Corticosteroid; Methotrexate; Mycophenolic acidMMF, mycophenolate mofetil; CsA, cyclosporin A; Mtx, methotrexate; -G, glucuronide; HSCT, hematopoietic stem cell transplantation; LC–MS/MS, high-perf

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Targeting TNF superfamily members for therapeutic intervention in rheumatoid arthritis

Keywords: MTX، متوترکسات; Tumor necrosis factor superfamily; Rheumatoid arthritis; B cells; T cells; TherapyTNFRSF, tumor necrosis factor receptor superfamily; RA, rheumatoid arthritis; DC, dendritic cells; MTX, methotrexate; HL, Hodgkin’s lymphoma

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Integrated safety analysis: Short- and long-term safety profiles of etanercept in patients with psoriasis

Keywords: MTX، متوترکسات; clinical trials; etanercept; long-term treatment; psoriasis; safetyAE, adverse event; BCC, basal cell carcinoma; BIW, twice weekly; CHF, congestive heart failure; CI, confidence interval; MI, myocardial infarction; MTX, methotrexate; NMSC, nonmelanoma ski

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting

Keywords: MTX، متوترکسات; Folate receptor; Methotrexate; Poly(amidoamine) dendrimer; Targeted drug delivery; Multivalent binding; Dual activityFA, folic acid; FAR, folic acid receptor; MTX, methotrexate; PAMAM, polyamidoamine; SPR, surface plasmon resonance; DHFR, dihydrofolate re

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Development of a fluorescently labeled thermostable DHFR for studying conformational changes associated with inhibitor binding

Keywords: MTX، متوترکسات; Bs, Bacillus stearothermophilus; DHFR, dihydrofolate reductase; THF, tetrahydrofolate; MTX, methotrexate; TMP, trimethoprim; MDCC, N-[2-(1-maleimidyl)ethyl]-7-(diethylamino)coumarin-3-carboxamideProtein–ligand interactions; Dihydrofolate reductase; Confor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Novel gene markers of immunosuppressive chemicals in mouse lymph node assay

Keywords: MTX، متوترکسات; AZ, azathioprine; CPA, cyclophosphamide; CsA, cyclosporin A; DEX, dexamethasone; DMSO, dimethylsulfoxide; DNCB, dinitrochlorobenzene; LLNA, local lymph node assay; MTX, methotrexate; PSL, prednisolone; qPCR, quantitative reverse transcription-polymerase c

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Polyvalent saccharide-functionalized generation 3 poly(amidoamine) dendrimer–methotrexate conjugate as a potential anticancer agent

Keywords: MTX، متوترکسات; PAMAM, polyamidoamine; G3, generation 3; MTX, methotrexate; FA, folic acid; FR, folate receptor; SPR, Surface Plasmon Resonance; FBP, folate-binding protein; FI, fluorescein-5(6)-carboxamidohexanoic acid; PDI, polydispersity indexTargeting anticancer drug

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Underexpression of miR-224 in methotrexate resistant human colon cancer cells

Keywords: MTX، متوترکسات; MTX, methotrexate; DHFR, dihydrofolate reductase; miR and miRNA, microRNA; CRC, colorectal carcinoma; PDAC, pancreatic ductal adenocarcinoma; APRT, adenine phosphoribosyltransferase; CDS2, CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

A systematic review of morphea treatments and therapeutic algorithm

Keywords: MTX، متوترکسات; localized scleroderma; therapeuticsBB, broadband; ECDS, en coup de sabre; IV, intravenous; IVMP, intravenous methylprednisone; MSS, Modified Skin Score; MTX, methotrexate; NB, narrowband; PCMT, pulsed intravenous corticosteroids plus methotrexate; PUVA, p

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

Single anti-P ribosomal antibodies are not associated with lupus nephritis in patients suffering from active systemic lupus erythematosus

Keywords: MTX، متوترکسات; SLE, systemic lupus erythematosus; LN, lupus nephritis; ALN, active LN; AZP, azathioprine; MPN, methylprednisolone; CYC, cyclophosphamide; MFM, mycophenolate mophetyl; CHQ, chloroquine; MTX, methotrexate; PDN, prednisolone; DFZ, deflazacort; HCQ, hydroxyc

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

2,4-Diamino-5-methyl-6-substituted arylthio-furo[2,3-d]pyrimidines as novel classical and nonclassical antifolates as potential dual thymidylate synthase and dihydrofolate reductase inhibitors

Keywords: MTX، متوترکسات; TS, thymidylate synthase; dTMP, 2′-deoxythymidine-5′-monophosphate; dUMP, 2′-deoxyuridine-5′-monophosphate; DHFR, dihydrofolate reductase; dTDP, 2′-deoxythymidine-5′-diphosphate; dTTP, 2′-deoxythymidine-5′-triphosphate; MTX, methotrexate; GARFT, glycinami

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Micronucleus and comet assay in the peripheral blood of juvenile rat: Establishment of assay feasibility, time of sampling and the induction of DNA damage

Keywords: MTX، متوترکسات; CIS, cisplatin; CBL, chlorambucil; CP, cyclophosphamide; ERTs, erythrocytes; MTX, methotrexate; MN, micronucleus; MNERTs, micronucleated erythrocytes; MNRETs, micronucleated reticulocytes; PACLI, paclitaxel; PBE, peripheral blood erythrocytes; PBMN, perip

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Psoriasis in patients with HIV infection: From the Medical Board of the National Psoriasis Foundation

Keywords: MTX، متوترکسات; biologicals; HIV; phototherapy; psoriasis; systemic therapy; topical therapyCSA, cyclosporine; MTX, methotrexate; PASI, Psoriasis Area and Severity Index; PUVA, psoralen plus ultraviolet A; TNF, tumor necrosis factor; UV, ultraviolet

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Evaluation of multi-organ DNA damage by comet assay from 28 days repeated dose oral toxicity test in mice: A practical approach for test integration in regulatory toxicity testing

Keywords: MTX، متوترکسات; MTX, methotrexate; MN, micronucleus; IWGTP, International Workshop on Genotoxicity Test Procedures; REACH, Registration Evaluation Authorization Restriction of Chemicals; MDA, malondialdehyde; GSH, glutathione; RETs, reticulocytes; NCEs, normochromatic er

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Intralesional chemotherapy for nonmelanoma skin cancer: A practical review

Keywords: MTX، متوترکسات; basal cell carcinoma; bleomycin; chemotherapy; fluorouracil; interferon; intralesional; keratoacanthoma; methotrexate; squamous cell carcinomaBCC, basal cell carcinoma; CR, complete response; 5FU, 5-fluoruracil; KA, keratoacanthoma; MTX, methotrexate; NMS

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Efficacy and safety of treatments for childhood psoriasis: A systematic literature review

Keywords: MTX، متوترکسات; childhood psoriasis; efficacy; safety; treatmentLOE, level of evidence; MTX, methotrexate; NB, narrowband; PASI, Psoriasis Area and Severity Index; PUVA, psoralen plus ultraviolet A; RCT, randomized controlled trial; UV, ultraviolet

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2010 سفارش ترجمه

Methotrexate-related lymphoproliferative disorder with extensive vascular involvement in a patient with rheumatoid arthritis

Keywords: MTX، متوترکسات; EB virus; Hodgkin lymphoma; methotrexate; thrombophlebitisEB, Epstein-Barr; HL, Hodgkin lymphoma; LPD, lymphoproliferative disorder; MTX, methotrexate; MTX-LPD, methotrexate-related lymphoproliferative disorder; RA, rheumatoid arthritis

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Methotrexate in Pediatric Osteosarcoma: Response and Toxicity in Relation to Genetic Polymorphisms and Dihydrofolate Reductase and Reduced Folate Carrier 1 Expression

Keywords: MTX، متوترکسات; DHFR, Dihydrofolate reductase; GAPDH, Glyceraldehyde-3-phosphate dehydrogenase mRNA; HD-MTX, High-dose methotrexate; MTHFR, 5,10-Methylenetetrahydrofolate reductase; MTR, Methionine synthase; MTX, Methotrexate; OR, Odds ratios; RFC1, Reduced folate carrie

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Immunohistochemical diagnosis of methylthioadenosine phosphorylase (MTAP) deficiency in non-small cell lung carcinoma

Keywords: MTX، متوترکسات; NSCLC, non-small cell lung cancer; MTAP, methylthioadenosine phosphorylase; MTA, methylthioadenosine; IHC, immunohistochemistry; PCR, polymerase chain reaction; MTR1P, 5-methylthioribose-1-phosphate; MTX, methotrexate; DDATHF, dideazatetrahydrofolate; FIS

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Peptidylarginine deiminases and the pathogenesis of rheumatoid arthritis: A reflection of the involvement of transglutaminase in coeliac disease

Keywords: MTX، متوترکسات; ACPA, anti-citrullinated peptide antibody; CD, coeliac disease; DTT, dithiothreitol; EDTA, ethylenediaminetetraacetic acid; EMA, endomysial antibodies; FXIII, factor XIII; GAD, glutamic acid decarboxylase; MTX, methotrexate; PAD, peptidylarginine deiminas

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Novel insulin-like growth factor-methotrexate covalent conjugate inhibits tumor growth in vivo at lower dosage than methotrexate alone

Keywords: MTX، متوترکسات; EDC, 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride; FACS, fluorescent activated cell sorting; FCS, fetal calf serum; IGF, insulin-like growth factor; IGFPBs, circulating IGF-binding proteins; IR, insulin receptor; MTX, methotrexate; SDS-PAGE

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Gene expression profiling of leukemia T-cells resistant to methotrexate and 7-hydroxymethotrexate reveals alterations that preserve intracellular levels of folate and nucleotide biosynthesis

Keywords: MTX، متوترکسات; MTX, methotrexate; 7-OHMTX, 7-hydroxymethotrexate; IC50, the drug concentration inhibiting cell growth by 50%; DHFR, dihydrofolate reductase; TS, thymidylate synthase; RFC, reduced folate carrier; FPGS, folylpolyglutamate synthetase; FPGH, folylpolyglutam

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Alefacept with methotrexate for treatment of psoriatic arthritis: Open-label extension of a randomized, double-blind, placebo-controlled study

Keywords: MTX، متوترکسات; ACR, American College of Rheumatology; ACR20, 20% Reduction in American College of Rheumatology criteria; ALT, alanine aminotransferase; AST, aspartate aminotransferase; MTX, methotrexate; PASI, Psoriasis Area and Severity Index; PsA, psoriatic arthritis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Charged Amino Acids in a Preprotein Inhibit SecA-Dependent Protein Translocation

Keywords: MTX، متوترکسات; PMF, proton motive force; TMS, transmembrane segments; IMV, inner membrane vesicle; DHFR, dihydrofolate reductase; Mtx, methotrexate; AMP-PNP, adenosine 5′-(β,γ-imido)triphosphate; ATP-γ-S, adenosine 5′-[γ-thio]triphosphate; BSA, bovine serum albuminSecA;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Mutational ‘hot-spots’ in mammalian, bacterial and protozoal dihydrofolate reductases associated with antifolate resistance: Sequence and structural comparison

Keywords: MTX، متوترکسات; DHFR, dihydrofolate reductase; MTX, methotrexate; TMP, trimethoprim; CYC, cycloguanil; PYR, pyrimethamine; NADPH, nicotinamide adenine dinucleotide phosphate (reduced form); DHF, 7,8-dihydrofolate; THF, 5,6,7,8-tetrahydrofolate; PMTX, pemetrexed; TMTX, tr

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه