Keywords: جهش p53; Osteosarcoma; Che-1; Mutant p53; Cell apoptosisOS, osteosarcoma; ChIP, chromatin immunoprecipitation; AATF, apoptosis-antagonizing transcription factor; Pol II, polymerase II; DDR, DNA damage response; FBS, fetal bovine serum
مقالات ISI جهش p53 (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Mutant p53 as a therapeutic target for the treatment of triple-negative breast cancer: Preclinical investigation with the anti-p53 drug, PK11007
Keywords: جهش p53; mutant p53; breast cancer; triple-negative breast cancer; 2-sulfonylpyrimidine PK11007; PRIMA-1MET; APR-246;
Nimbolide reduces CD44 positive cell population and induces mitochondrial apoptosis in pancreatic cancer cells
Keywords: جهش p53; Pancreatic cancer; Nimbolide; Apoptosis; Mutant p53; Cancer stem cells; Mitochondria;
Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity
Keywords: جهش p53; Mutant p53; Pancreas cancer; GAPDH; AMPK; AKT; SIRT1;
Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines
Keywords: جهش p53; Mutant p53; Structure-based drug discovery; Anticancer therapy;
ReviewMolecular interplay between mutant p53 proteins and autophagy in cancer cells
Keywords: جهش p53; Mutant p53; Autophagy; Cancer;
1,25-Dihydroxyvitamin D3 suppresses gastric cancer cell growth through VDR- and mutant p53-mediated induction of p21
Keywords: جهش p53; 1,25-Dihydroxyvitamin D3; VDR; Gastric cancer; p21; Mutant p53;
Gambogic acid counteracts mutant p53 stability by inducing autophagy
Keywords: جهش p53; Gambogic acid; Autophagy; Mutant p53; Apoptosis;
Transcriptome profiling identifies genes and pathways deregulated upon floxuridine treatment in colorectal cancer cells harboring GOF mutant p53
Keywords: جهش p53; Mutant p53; Gain-of-function; Transcriptome; Colorectal cancer; Floxuridine; Chemoresistance
Mutant p53 proteins alter cancer cell secretome and tumour microenvironment: Involvement in cancer invasion and metastasis
Keywords: جهش p53; Mutant p53; Cancer; Secretome; Microenvironment; Cytokines
A rare DNA contact mutation in cancer confers p53 gain-of-function and tumor cell survival via TNFAIP8 induction
Keywords: جهش p53; Mutant p53; Gain of function; Pro-survival; TNFα; Bax; BCL-2 associated X protein; CDKN1A; cyclin-dependent kinase inhibitor 1A; CPT; camptothecin; NF-κB; nuclear factor κB; qRT-PCR; quantitative real time polymerase chain reaction; Tet; tetracycline;
Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition
Keywords: جهش p53; Autophagy; Mutant p53; Gain-of-function; Cancer; mTOR; AMPK;
Tumor suppressor p53 and its mutants in cancer metabolism
Keywords: جهش p53; Tumor suppressor; p53; Mutant p53; Metabolism;
Distinct novel quinazolinone exhibits selective inhibition in MGC-803 cancer cells by dictating mutant p53 function
Keywords: جهش p53; Mutant p53; Selective inhibition; Quinazolinone; Apoptosis;
Mutant p53 (p53-R248Q) functions as an oncogene in promoting endometrial cancer by up-regulating REGγ
Keywords: جهش p53; EC; Mutant p53; REGγ; Proliferation; Invasion; EMT;
Mutant p53 stimulates chemoresistance of pancreatic adenocarcinoma cells to gemcitabine
Keywords: جهش p53; Pancreatic adenocarcinoma; Gemcitabine; Mutant p53; Gain-of-function (GOF); Autophagy; p53-reactivating molecules
Mutant p53 exerts oncogenic effects through microRNAs and their target gene networks
Keywords: جهش p53; Mutant p53; microRNA; miRNA; Let-7; miR-130b; miR-128-2; miR-155; miR-223; miR-27a; miR-205; Gain-of-function; Invasion; Metastasis; Cancer;
VDR primary targets by genome-wide transcriptional profiling
Keywords: جهش p53; 1α,25(OH)2D3; 1α,25-dihydroxyvitamin D3; ChIP; chromatin immunoprecipitation; ChIP-Seq; ChIP-sequencing; DAVID; Database for Annotation, Visualization and Integrated Discovery; FVKM; fragments per virtual kb per million; log2fc; log2 fold change; H3K4me
Gain-of-function of mutant p53: mutant p53 enhances cancer progression by inhibiting KLF17 expression in invasive breast carcinoma cells
Keywords: جهش p53; Metastasis; KLF17; Mutant p53; Breast cancer; Chemotherapy; Invasion;
Disarming mutant p53 oncogenic function
Keywords: جهش p53; Mutant p53; Cancer; Therapeutic strategies
Mutant p53 gain of function can be at the root of dedifferentiation of human osteosarcoma MG63 cells into 3AB-OS cancer stem cells
Keywords: جهش p53; CSCs; Cancer stem cells; FISH; Fluorescent in situ hybridization; GOF; Gain of function; MMPs; Matrix metalloproteinases; Mutp53; Mutant p53; OS; Osteosarcoma; Human osteosarcoma; Cancer stem cells; Mutant p53 gain of function; Cancer cell dedifferentiati
p53 mutants induce transcription of NF-κB2 in H1299 cells through CBP and STAT binding on the NF-κB2 promoter and gain of function activity
Keywords: جهش p53; Mutant p53; Gain of function; Transactivation
para-Phenylenediamine-induced autophagy in human uroepithelial cell line mediated mutant p53 and activation of ERK signaling pathway
Keywords: جهش p53; para-Phenylenediamine; SV-HUC-1 cells; Autophagy; Mutant p53; Beclin-1;
Detection of mutant p53 using field-effect transistor biosensor
Keywords: جهش p53; Metal oxide semiconductor field-effect transistor; Biosensor; p53; Mutant p53; DNA-binding domain
PRIMA-1 cytotoxicity correlates with nucleolar localization and degradation of mutant p53 in breast cancer cells
Keywords: جهش p53; PRIMA-1; Mutant p53; Nucleolus; p53 degradation; p53 ubiquitylation; Breast cancer;
RB18A enhances expression of mutant p53 protein in human cells
Keywords: جهش p53; RB18A/TRAP220/DRIP205; Mutant p53; p53 or MDM2 promoter