Keywords: MWM، ماریس آب موریس; CCH, chronic cerebral hypoperfusion; BCCAO, bilateral common carotid artery occlusion; MWM, Morris water maze; ORT, object recognition task; DI, discrimination index; GluR2, AMPA receptor 2; NMDAR, N-methyl-d-aspartate receptor; NR1, NMDAR1; VCI, vascular
مقالات ISI MWM، ماریس آب موریس (ترجمه نشده)
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Keywords: MWM، ماریس آب موریس; ANOVA, analysis of variance; LH, lateral hypothalamus; MORs, mu-opioid receptors; MWM, Morris water maze; OX1Rs, orexin-1 receptors; PFC, prefrontal cortexmorphine sensitization; OX1 receptors; CA1 regions; morris water maze; rat
Keywords: MWM، ماریس آب موریس; EE, enriched environment; SE, standard environment; SD, Sprague–Dawley; TEM, transmission electron microscope; DTI, diffuse tension image; MRI, magnetic resonance imaging; MWM, morris water maze; IUR, isotropic; ANOVA, one-way repeated-measures analysis o
Keywords: MWM، ماریس آب موریس; AChE, Acetylcholinesterase; ATC, Acetylthiocholine; CAT, Catalase; DTNB, Dithiobisnitrobenzoic acid; EPM, Elevated plus maze; FST, Forced swimming test; GPx, Glutathione peroxidase; MDA, Malondialdehyde; MWM, Morris water maze; NBT, Nitro blue tetrazolium
Keywords: MWM، ماریس آب موریس; REM, rapid eye movement; GDX, gonadectomized; SD, sleep deprivation; MWM, Morris water maze; WP, wide platform; LTP, long-term potentiation; BDNF, brain derived neurotrophic factor; fEPSPs, field excitatory post synaptic potentials; PPF, paired-pulse faci
Keywords: MWM، ماریس آب موریس; GA, Glatiramer acetate; CNS, central nervous system; MWM, Morris water maze; IL-6, Interleukin 6; BBB, blood–brain-barrier; self-Ag, self-antigen; CSF, cerebrospinal fluid; IGF-1, insulin-like growth factor 1; BDNF, brain-derived neurotrophic factor; NPCS
Traumatic brain injury accelerates amyloid-β deposition and impairs spatial learning in the triple-transgenic mouse model of Alzheimer’s disease
Keywords: MWM، ماریس آب موریس; Aβ, β−amyloid; AD, Alzheimer’s disease; APP, amyloid−β precursor protein; MWM, Morris water maze; TBI, traumatic brain injuryAlzheimer’s disease; Amyloid-β protein; Cognitive impairment; Traumatic brain injury; Triple-transgenic AD-model mouse
TSPO ligand PK11195 alleviates neuroinflammation and beta-amyloid generation induced by systemic LPS administration
Keywords: MWM، ماریس آب موریس; Aβ, β-amyloid protein; AD, Alzheimer’s disease; APP, amyloid precursor protein; BACE, β-site APP cleaving enzyme; BDNF, brain-derived neurophic factor; COX, cyclooxygenase; IDE, insulin-degrading enzyme; LPS, lipopolysaccharide; MWM, Morris water maze; SE
Alpha-tocopherol quinine ameliorates spatial memory deficits by reducing beta-amyloid oligomers, neuroinflammation and oxidative stress in transgenic mice with Alzheimer's disease
Keywords: MWM، ماریس آب موریس; AD, Alzheimer’s disease; Aβ, beta amyloid; α-TQ, alpha-tocopherol quinine; MWM, morris water maze; ROS, reactive oxygen species; ThS, thioflavin S; Iba-1, ionized calcium binding adaptor molecule-1; MDA, malondialdehyde; SOD, super oxide dismutase; IL-1β,
Dizocilpine (MK-801) impairs learning in the active place avoidance task but has no effect on the performance during task/context alternation
Keywords: MWM، ماریس آب موریس; AAPA, active allothetic place avoidance; ANOVA, analysis of variance; i.p., intraperitoneal application; MWM, Morris water maze; NMDA, N-methyl-d-aspartate; S.E.M., standard error of the meanTask alternation; Context alternation; Active place avoidance; M
Prenatal exposure to a novel antipsychotic quetiapine: Impact on neuro-architecture, apoptotic neurodegeneration in fetal hippocampus and cognitive impairment in young rats
Keywords: MWM، ماریس آب موریس; AAPD, atypical antipsychotic drug; QUE, quetiapine; HAL, haloperidol; CNS, central nervous system; MHRD, maximum human recommended doses; GD, gestation day; PND, postnatal day; MWM, Morris water maze; PAM, passive avoidance maze; BW, body weight; ANOVA, a
Tenuifolin, a secondary saponin from hydrolysates of polygalasaponins, counteracts the neurotoxicity induced by Aβ25–35 peptides in vitro and in vivo
Keywords: MWM، ماریس آب موریس; AD, Alzheimer's disease; Aβ, Amyloid beta-Protein; Aβ25–35, Amyloid beta-Protein Fragment 25–35; HPS, Hydrolysate of polygalasaponins; MWM, Morris water maze; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; DMEM, Dulbecco's Modified Eag
Neuronal reorganization in adult rats neonatally exposed to (±)-3,4-methylenedioxymethamphetamine
Keywords: MWM، ماریس آب موریس; 5-HT, serotonin; ANOVA, analysis of variance; CWM, Cincinnati water maze; DG, dentate gyrus; EC, entorhinal cortex; MDMA, methylenedioxymethamphetamine; MWM, Morris water maze; NAcc, nucleus accumbens; P, postnatal day; SAL, salineDevelopment; Golgi–Cox s
Quercetin improves hypoxia-ischemia induced cognitive deficits via promoting remyelination in neonatal rat
Keywords: MWM، ماریس آب موریس; CC, corpus callosum; CNS, central nervous system; HI, hypoxia-ischemia; MWM, Morris water maze; OL, oligodendrocytes; OPC, oligodendrocyte progenitor cell; PHI, perinatal cerebral hypoxia-ischemia; Que, quercetin; TEM, transmission electron microscopy; WM
Acrolein induces Alzheimer's disease-like pathologies in vitro and in vivo
Keywords: MWM، ماریس آب موریس; AD, Alzheimer's disease; Aβ, amyloid-beta peptide; ADAM-10, A-disintegrin and metalloprotease 10; APP, amyloid precursor protein; GFAP, glial fibrillary acidic protein; MAPK, mitogen-activated protein kinase; MDA, malondialdehyde; MWM, Morris Water Maze;
Developmentally-induced hypothyroidism alters the expression of Egr-1 and Arc genes and the sensitivity to cannabinoid agonists in the hippocampus. Possible implications for memory and learning
Keywords: MWM، ماریس آب موریس; CB1R, cannabinoid type 1 receptor; MWM, Morris Water Maze; T4, l-thyroxine; T3, 3,5,3′-triiodothyronine; CREB, cAMP responsive element binding protein; WIN 55,212-2, R-(+)-(2,3-dihydro-5-methyl)-3-[(morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazinyl](1
Behavioural alterations relevant to developmental brain disorders in mice with neonatally induced ventral hippocampal lesions
Keywords: MWM، ماریس آب موریس; %SA, percentage spontaneous alternation; ADHD, attention deficit hyperactivity disorder; ANOVA, analysis of variance; EPM, elevated plus maze; i.p., intraperitoneal; LARGE, large neonatal ventral hippocampal lesion; MWM, Morris water maze; NVHL, neonatal
Early cognitive stimulation compensates for memory and pathological changes in Tg2576 mice
Keywords: MWM، ماریس آب موریس; AD, Alzheimer's disease; CS, cognitive stimulation; MWM, Morris Water Maze; NOR, novel object recognition; WT, wild-typeCognitive training; hAPP transgenic mouse; Synaptic; Amyloid; Tau
The role of gangliosides in brain development and the potential benefits of perinatal supplementation
Keywords: MWM، ماریس آب موریس; DHA, docosahexaenoic acid; Cer, ceramide; CML, complex milk lipids; Gal, galactose; Glu, glucose; GMDS, Griffiths Mental Development Scale; Neu5Ac, N-acetylneuraminic acid; MWM, Morris Water Maze; NORT, Novel Object Recognition Task; SA, sialic acidGangli
Early life exposure to sevoflurane impairs adulthood spatial memory in the rat
Keywords: MWM، ماریس آب موریس; Sevoflurane; Memory; Neonate; Pediatrics; Inhalation anesthesia; Neuronal toxicityAUC, area under curve; BID, twice a day; MAC, minimum alveolar concentration; MWM, Morris Water Maze; P3D, postnatal 3 days; P7D, postnatal 7 days; P14D, postnatal 14 days;
Polydatin protects learning and memory impairments in a rat model of vascular dementia
Keywords: MWM، ماریس آب موریس; VaD, vascular dementia; MCAO, middle cerebral artery occlusion; 4-VO, four-vessel occlusion; SOD, superoxide dismutase; CAT, catalase; MDA, malondialdehyde; MWM, morris water maze; OGD, oxygen-glucose deprivation; ROS, reactive oxygen species; Cnos, const
Learning, memory, and glial cell changes following recovery from chronic unpredictable stress
Keywords: MWM، ماریس آب موریس; CUS, chronic unpredictable stress; MWM, Morris water maze; mPFC, medial prefrontal cortex; PL, prelimbicMicroglia; Astrocyte; Recovery; Chronic unpredictable stress; Change
Bright lighting conditions during testing increase thigmotaxis and impair water maze performance in BALB/c mice
Keywords: MWM، ماریس آب موریس; MWM, Morris water maze; BLC, bright light condition; DLC, dim light conditionMorris water maze task; BALB/c mice; Light condition; Thigmotaxis
Inhibition of PKA attenuates memory deficits induced by β-amyloid (1–42), and decreases oxidative stress and NF-κB transcription factors
Keywords: MWM، ماریس آب موریس; AD, Alzheimer's disease; Aβ, amyloid β; PKA, protein kinase A; NFκB, nuclear factor-κB; γ-GCS, glutamylcysteine synthetase; HO-1, hemeoxygenase-1; GSH, glutathione; SOD, superoxide dismutase; MAPK, mitogen-activated protein kinase; MWM, Morris water maze;
Intranasal administration of nerve growth factor ameliorate β-amyloid deposition after traumatic brain injury in rats
Keywords: MWM، ماریس آب موریس; Aβ, amyloid-β; AD, Alzheimer's disease; APP, amyloid protein precursor; CNS, central nervous system; ELISA, enzyme-linked immunosorbent assay; IN, intranasal; INA, intranasal application; MWM, Morris water maze; NGF, nerve growth factor; p75NTR, p75 neuro
Nicotine attenuates spatial learning deficits induced by sodium metavanadate
Keywords: MWM، ماریس آب موریس; SMV, sodium metavanadate; MWM, morris water maze; ChAT, choline acetyltransferase; VAChT, vesicular acetylcholine transporter; nAChRs, nicotinic acetylcholine receptors; MSA, medial septal area; MAPK, mitogen-activated protein kinase; CREB, cAMP response
Low-dose neonatal domoic acid causes persistent changes in behavioural and molecular indicators of stress response in rats
Keywords: MWM، ماریس آب موریس; DOM, domoic acid; CRF, corticotrophin-releasing factor; PND, postnatal day; SAL, saline; EPM, elevated plus maze; MWM, Morris water maze; AN, anterior nuclear; AM, anterior membrane/cytosol; HN, hippocampal nuclear; HM, hippocampal membrane/cytosol; PN, p
Electroacupuncture pretreatment prevents cognitive impairment induced by limb ischemia–reperfusion via inhibition of microglial activation and attenuation of oxidative stress in rats
Keywords: MWM، ماریس آب موریس; LI/R, limb ischemia–reperfusion; CA1, Cornu Ammonis area1; MWM, Morris water maze; ROS, reactive oxygen species; MDA, malondialdehyde; SOD, superoxide dismutase; DCF-DA, dichlorofluorescein diacetate; EA, electroacupuncture; Iba 1, ionized calcium binding
Stress-induced impairments in prefrontal-mediated behaviors and the role of the N-methyl-d-aspartate receptor
Keywords: MWM، ماریس آب موریس; stress; prefrontal cortex; cognition; extinction; glutamate; N-methyl-D-aspartatePFC, prefrontal cortex; NMDAR, N-methyl-d-aspartate receptor; mPFC, medial prefrontal cortex; CUS, chronic unpredictable stress; MWM, Morris water maze; DLS, dorsolateral str
Object recognition testing: Rodent species, strains, housing conditions, and estrous cycle
Keywords: MWM، ماریس آب موریس; ORT, object recognition task; T1, trial 1; T2, trial 2; e1, object exploration during trial 1; e2, object exploration during trial 2; d1, discrimination index; d2, relative discrimination index corrected for exploration time; MWM, Morris water maze; i.p,
Effect of prenatal pentylenetetrazol-induced kindling on learning and memory of male offspring
Keywords: MWM، ماریس آب موریس; prenatal seizure; pentylenetetrazol; Morris water maze; shuttle-box; learning and memoryANOVA, analysis of variance; MWM, Morris water maze; PTZ, pentylenetetrazol
Autophagy is involved in traumatic brain injury-induced cell death and contributes to functional outcome deficits in mice
Keywords: MWM، ماریس آب موریس; traumatic brain injury; autophagy; apoptosis; LC3; p62BFA, bafliomycin A1; LC3, microtubule-associated protein 1A/1B light chain 3; MWM, Morris water maze; PI, propidium iodide; PI3K, phoshatidylinositol-3-kinase; p62, p62/SQSTM1; TBI, traumatic brain inj
Post-injury administration of NAAG peptidase inhibitor prodrug, PGI-02776, in experimental TBI
Keywords: MWM، ماریس آب موریس; ATM, atmosphere; BBB, blood–brain barrier; CNS, central nervous system; FJ-B, Fluoro-Jade B; GCP II, glutamate carboxypeptidase II; i.p., intraperitoneal; mGluR3, metabotropic glutamate receptor (subtype 3); MWM, Morris water maze; NAA, N-acetylaspartate;
Davunetide (NAP) as a preventative treatment for central nervous system complications in a diabetes rat model
Keywords: MWM، ماریس آب موریس; DM, diabetes mellitus; CNS, central nervous system; STZ, streptozotocin; MWM, Morris water maze; DG, dentate gyrus; ADNP, activity-dependent neuroprotective protein; PFA, paraformaldehyde; Casp-3, caspase-3; PFC, prefrontal cortex; GFAP, glial fibrillary
Spatial and emotional memory in aged rats: a behavioral-statistical analysis
Keywords: MWM، ماریس آب موریس; aging; memory; emotion; spatial memory; emotional memoryCS, conditioned stimulus; LTP, long-term potentiation; MWM, Morris water maze; UCS, unconditioned stimulus
Exercise contributes to the effects of DHA dietary supplementation by acting on membrane-related synaptic systems
Keywords: MWM، ماریس آب موریس; DHA, docosahexaenoic acid; DHA-Exc, DHA diet-exercise; DHA-Sed, DHA diet-sedentary; GAP-43, growth-associated protein 43; MWM, Morris water maze; RD-Exc, regular diet-exercise; RD-Sed, regular diet-sedentary; STX-1, syntaxin-1; STX-3, syntaxin-3Omega-3 fa
Maternal supplementation with a complex milk lipid mixture during pregnancy and lactation alters neonatal brain lipid composition but lacks effect on cognitive function in rats
Keywords: MWM، ماریس آب موریس; ANOVA, analysis of variance; CML, complex milk lipid; DHA, docosahexaenoic acid; MWM, Morris water maze; NORT, Novel object recognition test; PC, phosphatidylcholineRat; Nutrition; Complex milk lipids; Gangliosides; Phospholipids; Growth; Behavior; Cognit
A critical review of chronic stress effects on spatial learning and memory
Keywords: MWM، ماریس آب موریس; DSM IV, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition; HPA, Hypothalamic–pituitary–adrenal; MWM, Morris water maze; NS, Non-significant; RAM, Radial arm maze; RAWM, Radial arm water maze; RM, Reference memory; WM, Working memoryHip
Repeated ethanol exposure affects the acquisition of spatial memory in adolescent female rats
Keywords: MWM، ماریس آب موریس; AUD, alcohol-use disorder; MWM, Morris water maze; PD, postnatal dayMorris water maze; Juvenile; Adult; Age-related; Alcohol; Learning and memory; Brain development; Cognition
NAP protects memory, increases soluble tau and reduces tau hyperphosphorylation in a tauopathy model
Keywords: MWM، ماریس آب موریس; NAP, NAPVSIPQ; AD, Alzheimer's disease; ADNP, activity-dependent neuroprotective protein; MWM, Morris water maze; htau, human tau; DM-Tau-tg, double mutant tau transgenic mice; NFTs, neurofibrillary tangles; w.t., wild-typeTau; Tauopathy; NAP; Neurodegene
Effect of reversible inactivation of locus ceruleus on spatial reference and working memory
Keywords: MWM، ماریس آب موریس; working memory; reference memory; Morris water maze; reversible inactivation; LC; noradrenergic systemAch, acetylcholine; DNB, dorsal noradrenergic bundle; LC, locus coeruleus; MSA, medial septal area; MWM, Morris water maze; NE, norepinephrine; PH, prepo
Intra-cornu ammonis 1 administration of the human immunodeficiency virus-1 protein trans-activator of transcription exacerbates the ethanol withdrawal syndrome in rodents and activates N-methyl-d-aspartate glutamate receptors to produce persisting spatial
Keywords: MWM، ماریس آب موریس; alcoholism; AIDS; memory; substance abuse; HIV-associated dementia; hippocampusBEL, blood ethanol level; CA1, cornu ammonis 1; EtOH, ethanol; HIV, human immunodeficiency virus; HIV-1, human immunodeficiency virus-1; MWM, Morris water maze; NMDA, N-methyl-
Arsenic moiety in gallium arsenide is responsible for neuronal apoptosis and behavioral alterations in rats
Keywords: MWM، ماریس آب موریس; As (III), arsenic; ROS, reactive oxygen species; NO, nitric oxide; ΔΨm, Mitochondrial membrane potential; AO/EB staining, Acridine orange/Ethium bromide staining; MWM, Morris Water Maze; GPx, glutathione peroxidase activity; GST, glutathione S-Transfereas
Hippocampal gene expression changes during age-related cognitive decline
Keywords: MWM، ماریس آب موریس; MWM, Morris water maze; AU, Age unimpaired; AI, Age impairedAging; Memory; Hippocampus; Morris water maze; Microarray
Supplementation with a mixture of complex lipids derived from milk to growing rats results in improvements in parameters related to growth and cognition
Keywords: MWM، ماریس آب موریس; ANOVA, analysis of variance; BMD, bone mineral density; CML, complex milk lipid; DEXA, dual-energy x-ray absorptiometry; IP, intraperitoneally; MWM, Morris water maze; NORT, Novel Object Recognition TaskRat; Nutrition; Complex milk lipids; Gangliosides; G
Hybridizing behavioral models: A possible solution to some problems in neurophenotyping research?
Keywords: MWM، ماریس آب موریس; OCD, obsessive compulsive disorder; FST, forced swim test; MWM, Morris water maze; OFT, open field test; NT, neurological tests; ST, swim testsBehavioral phenotyping; Experimental models; High-throughput testing; Research strategies; Single and multiple d
Hippocampal angiotensin II receptors play an important role in mediating the effect of voluntary exercise on learning and memory in rat
Keywords: MWM، ماریس آب موریس; AT1, Angiotensin II type I; ANOVA, analysis of variance; BDNF, brain-derived neurotrophic factor; MWM, Morris water maze; S.E.M., standard error of the mean; S.L.M., Stratum Lacunosum Moleculare; SUB., Subiculum; SUMS, Semnan University of Medical Science
Post-training CB1 cannabinoid receptor agonist activation disrupts long-term consolidation of spatial memories in the hippocampus
Keywords: MWM، ماریس آب موریس; cannabinoids; CB1 receptor; consolidation; hippocampus; spatial memory; WIN 55,212-2CB1R, cannabinoid receptor 1; CB2R, cannabinoid receptor 2; DMSO, dimethylsulfoxide; LTP, long term potentiation; MWM, Morris water maze; NMDAR, N-methyl-d-aspartate recep
Mammillary body alterations and spatial memory impairment in Wistar rats with thioacetamide-induced cirrhosis
Keywords: MWM، ماریس آب موریس; HE, hepatic encephalopathy; TAA, Thioacetamide; GFAP-IR, glial fibrillary acidic protein-immunoreactive; MWM, Morris Water Maze; MMn, medial mammillary nucleus; MMl, medial lateral mammillary nucleus; LM, lateral mammillary nucleus; BW, body weight; LW, l
Editing of the serotonin 2C receptor pre-mRNA: Effects of the Morris Water Maze
Keywords: MWM، ماریس آب موریس; Htr2c, serotonin receptor 2C; I, inosine; A, adenosine; G, guanosine; MWM, Morris Water Maze; SC, swimming control.5HT2C receptor; Inosine; Protein isoforms; Primer extension; Spatial learning; Stress