Keywords: Blood-brain barrier (BBB); Peptides; N-methylation; PAMPA; Permeability;
مقالات ISI (ترجمه نشده)
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Liquid chromatography-high resolution mass spectrometric methods for the surveillance monitoring of cyanotoxins in freshwaters
Keywords: Adda; (2S,3S,8S,9S)â3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid; ANP; anabaenopeptin; CID; collision-induced dissociation; dm; demethyl; EIC; extracted ion chromatogram; HRMS; high resolution mass spectrometry; IS; internal standard
Keywords: Aluminophosphate; Crystal structure; N-methylation; Solvothermal synthesis;
Keywords: In situ; N-methylation; Zinc phosphite; Helical channel; Crystal structure;
Improving oral bioavailability of cyclic peptides by N-methylation
Keywords: Bioavailability; Cyclic peptides; N-Methylation; Peptide-based drugs; Caco-2; Peptidomimetics; Membrane transport; Cyclosporin A;
The kinetic analysis of the N-methylation of 4-phenylpyridine by nicotinamide N-methyltransferase: Evidence for a novel mechanism of substrate inhibition
Keywords: 4-PP; 4-phenylpyridine; DMSO; dimethylsulphoxide; DV; dependent variable; hNNMT; recombinant human NNMT; IV; independent variable; kcat/Km; catalytic efficiency; MeNH; 2N-methylnorharman; MMP; mitochondrial membrane potential; MPP+; 1-methyl-4-phenylpyrid
Synthesis and structure of N-methylated azacalix[4]pyridines and azacalix[1]arene[3]pyridines
Keywords: Heteracalixaromatics; Azacalix[4]pyridine; Azacalix[1]arene[3]pyridine; N-methylation; Macrocycle;
Structure and dynamics of cyclic amides: The rotational spectrum of 1,3-dimethyl-2-imidazolidinone
Keywords: Rotational spectroscopy; Supersonic expansion; Lactam; N-methylation; Internal rotation; Two equivalent methyl tops;
Impact of N-methylation of the substance P 1-7 amide on anti-allodynic effect in mice after peripheral administration
Keywords: Anti-allodynia; Spared nerve injury (SNI); Substance P (SP); SP1-7 amide; Solid phase peptide synthesis (SPPS); N-methylation;
Synthesis of fluazolate via the application of regioselective [3+2] cyclocondensation and nucleophilic substitution-cyclization strategies
Keywords: Trifluoromethylpyrazole; [3+2] Cyclocondensation; Fluazolate; Regioselective; N-methylation;
Reductive N-methylation of amines with calcium hydride and Pd/C catalyst
Keywords: CaH2; Calcium hydride; Reductive amination; N-methylation; Amine;
N4-methylation changes the conformation of (3S,6S)-3-alkyl-6-benzylpiperazine-2,5-diones from folded to extended
Keywords: Piperazine-2,5-dione; N-methylation; Folded conformation; Extended conformation; CH/π interaction; X-ray crystal structure
11C-labeling and preliminary evaluation of pimavanserin as a 5-HT2A receptor PET-radioligand
Keywords: 5-HT2A receptor; PET; Pimavanserin; Carbon-11; N-methylation;
Synthesis and cyclisation studies of (E)-2-aryl-1-methyl-3-styrylquinolin-4(1H)-ones
Keywords: (E)-2-Aryl-1-methyl-3-styrylquinolin-4(1H)-ones; Benzo[c]acridin-7(12H)-ones; 4-Arylfuro[3,2-c]quinolones; Heck reaction; N-methylation;
A simple route to [11C]N-Me labeling of aminosuberic acid for proof of feasibility imaging of the xCâ transporter
Keywords: Radiolabelling; C-11; Oxidative stress; Cystine transporter; N-methylation;
O-(Aminosulfonylation) of phenols and an example of slow hydrolytic release
Keywords: Sulfonyldiimidazole; Drug conjugate; Sulfamate ester; N-methylation; Sulfatase;
Synthesis of IB-01212 by multiple N-methylations of peptide bonds
Keywords: Me2Leu; N,N-dimethylleucine; MeLeu; N-methylleucine; MePhe; N-methylphenylalanine; MSNT; 1-(mesitylene-2-sulfonyl)-3-nitro-1,2,4-triazole; NMI; 1-methylimidazole; DIEA; N,N-diisopropylethylamine; Cbz; benzyloxycarbonyl; Depsipeptide; Macrolactonization; N
New synthetic methods for 2,3-diarylacridin-9(10H)-one and (E)-2-aryl-4-styrylfuro[3,2-c]quinoline derivatives
Keywords: N-Methylation; Heck reaction; Electrocyclization reactions; Acridin-9(10H)-ones; Furoquinolines;
Exogenously acquired 16S rRNA methyltransferases found in aminoglycoside-resistant pathogenic Gram-negative bacteria: An update
Keywords: Aminoglycoside resistance; 16S rRNA methyltransferase; 16S rRNA methylase; N-methylation; Gram-negative pathogen; Plasmid-mediated; Exogenously acquired enzyme; S-adenosyl-l-methionine; NDM-1; Metallo-β-lactamase; KPC-2; OXA-23; CTX-M-type ESBL; PMQR; Mul
Per-N-methylated analogues of an antitumor bicyclic hexapeptide RA-VII
Keywords: RA-VII; Bouvardin; N-Methylation; X-ray crystallography; Rubia cordifolia; Cytotoxicity
Synthesis of diarylethene derivatives containing various heterocycles and tuning of light-emitting properties in a turn-on fluorescent diarylethene system
Keywords: Diarylethene; Imidazole; N-Methylation; Photochromism; Fluorescence; Metal ions
Molecular machines encoded by bacterially-derived multi-domain gene fusions that potentially synthesize, N-methylate and transfer long chain polyamines in diatoms
Keywords: Diatom; Biosilica glass; Long chain polyamine biosynthesis; N-methylation; AminopropyltransferaseLCPA, long chain polyamine; ODC, ornithine decarboxylase; AdoMet, S-adenosylmethionine; AdoMetDC, S-adenosylmethionine decarboxylase; MTA, methylthioadenosine
Synthesis of novel diarylethene compounds containing two imidazole bridge units and tuning of their optical properties
Keywords: Diarylethene; Imidazole; N-Methylation; Synthesis; Photochromism; Fluorescence
The first total synthesis of heteromine B, and an improved synthesis of heteromine A; natural products with antitumor activities
Keywords: Heteromine; Purine; Reductive alkylation; N-methylation; Antitumor compounds;
Effect of N-methylation on both ground and excited states properties of 1-(9-anthryl)-2-(2-benzothiazolyl) ethene
Keywords: Intramolecular charge transfer; Dual emission; N-methylation; Benzothiazole; Semiempirical molecular orbital calculations
N-Methylation of adamantane-substituted oxalamide unit affects its conformational rigidity: A skew conformation of the oxalamide bridge
Keywords: Adamantane; N-Methylation; Oxalamides; Retropeptides; X-ray structure analysis
N-Methyldehydroamino acids promote a configuration cis of N-methylamide bond
Keywords: N-Methylation; Dehydroamino acids; Tentoxin; Microcystin; Nodularin; trans-cis isomerisation; Potential energy surface;
Dopamine/serotonin receptor ligands. Part 15: Oxygenation of the benz-indolo-azecine LE 300 leads to novel subnanomolar dopamine D1/D5 antagonists
Keywords: Dopamine receptor ligands; Azecines; LE 300; Oxygenation; N-methylation
Selective mono-N-methylation of aniline substrates on Cu1−xZnxFe2O4
Keywords: N-methylation; Spinel; Selective N-methylation; N-methylaniline; Mono-N-methylation
Synthesis, characterization of cyclopalladated ferrocenylamines possessing both central and planar chirality: The crystal structure of (RC,RN,RP)-Ï-Pd[(η5- C5H5)Fe(η5-C5H3CH2N(CH3)CHCH3C6H5)]Cl(PPh3)  · 1/2H2O
Keywords: Ferrocenylamine; N-Methylation; Cyclopalladation; Chirality; Crystal;
A novel method for preparation of imidazolium tetrafluoroborate ionic liquids
Keywords: Ionic liquid; Syntheses; N-Methylation
Synthesis, characterization of [{(N-methyl-N-benzyl)amino}methyl]ferrocenes and their cyclopalladated complexes: Crystal structure of Ï-Pd[(η5-C5H5)Fe(η5-C5H3CH2N(CH3)CH2C6H4NO2-4)]Cl(PPh3)
Keywords: Ferrocenylamines; N-methylation; Cyclopalladation; Stereoselectivity; Crystal;
Methylation sites in tris(μ-thiolato)dimolybdenum(III) complexes
Keywords: Dimolybdenum complexes; Thiolato-bridged complexes; Sulfur- and nitrogen compounds; S-methylation; N-methylation; Crystal structure
Bilayer phase transitions of N-methylated dioleoylphosphatidylethanolamines under high pressure
Keywords: Bilayer membrane; N-Methylation; Phase transition; Pressure; Unsaturated phospholipid; Vesicle
On the “Active spacer and stabilizer” role of Zn in Cu1−xZnxFe2O4 in the selective mono-N-methylation of aniline: XPS and catalysis study
Keywords: Ferrite; N-Methylation; Aniline; N-Methylaniline; XPS; TPR; Spacer; Stabilizer; Surface distribution
Conformational studies into N-methylation of alanine diamide models: A quantitative approach
Keywords: N-Methylation; Hydrogen bond; Potential energy surface; Alanine;
An insight into the mechanism of selective mono-N-methylation of aniline on Cu1âxZnxFe2O4: a DRIFTS study
Keywords: Cu1âxZnxFe2O4; Aniline; Methanol; N-Methylation; DRIFT; IR; Reaction mechanism; N-Methylaniline; Desorption limited;