Extracellular NAD+ induces a rise in [Ca2+]i in activated human monocytes via engagement of P2Y1 and P2Y11 receptors
Keywords: NAD +; NAD+; Calcium; P2 receptors; LPS; Monocytes
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Synthesis of 4-Pyridoxolactone from Pyridoxine Using a Combination of Transformed Escherichia coli Cells
Keywords: NAD +; bioconversion; 4-pyridoxolactone; Escherichia coli cells; NAD+; pyridoxine;
High-throughput assays for sirtuin enzymes: A microfluidic mobility shift assay and a bioluminescence assay
Keywords: NAD +; SIRT; HTS; Mobility shift; Bioluminescence; NAD+; Deacetylase
Benzo[a]pyrene-induced necrosis in the HepG2 cells via PARP-1 activation and NAD+ depletion
Keywords: NAD +; Cell death; PARP-1; NAD+; Necrosis; Benzo[a]pyrene; HepG2
p53-, SIRT1-, and PARP-1-independent downregulation of p21WAF1 expression in nicotinamide-treated cells
Keywords: NAD +; Nicotinamide; NAD+; SIRT1; p21WAF1; Sp1; p53; PARP-1
Reagentless amperometric formaldehyde-selective biosensors based on the recombinant yeast formaldehyde dehydrogenase
Keywords: NAD +; Formaldehyde; Recombinant formaldehyde dehydrogenase; Glutathione; NAD+; Redox polymer; Amperometric biosensor
Highly stable amplified low-potential electrocatalytic detection of NAD+ at azure-chitosan modified carbon electrodes
Keywords: NAD +; NAD+; Chitosan; Electrocatalysis; Biosensor
P2X7 receptors mediate NADH transport across the plasma membranes of astrocytes
Keywords: NAD +; NADH; NAD+; Astrocyte; Transport; P2X7 receptor; Brain
The role of poly(ADP-ribose) polymerase-1 in CNS disease
Keywords: NAD +; DNA; transcription; inflammation; cell death; oxidative stress; AIF; apoptosis-inducing factor; DPQ 3; 4-dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone; EAE; experimental allergic encephalomyelitis; GPI 6150; 1,11b-dihydro-[2H]benzopyrano[4,3,2-
Identification of a critical site in Wlds: Essential for Nmnat enzyme activity and axon-protective function
Keywords: NAD +; HSV, Herpes simplex virus; NAD+, nicotinamide adenine dinucleotide; Nmnat, nicotinamide mononucleotide adenylyltransferase; SCG, superior cervical ganglion; Wlds, Wallerian degeneration slowNmnat1; NAD+; Axon degeneration
The antiviral drug ribavirin is a selective inhibitor of S-adenosyl-l-homocysteine hydrolase from Trypanosoma cruzi
Keywords: NAD +; 2Ã YT; 2Ã yeast extract tryptone; Ado; adenosine; AdoHcy; S-adenosyl-l-homocysteine; DTT; dl-Dithiothreitol; EDTA; ethylenediaminetetraacetic acid; FPLC; fast protein liquid chromatography; Hcy; l-homocysteine; HPLC; high performance liquid chromatograp
Entamoeba histolytica: ADP-ribosylation of secreted glyceraldehyde-3-phosphate dehydrogenase
Keywords: NAD +; Ameba; Cysteine synthase A; Extracellular GAPDH; Glyceraldehyde-3-phosphate dehydrogenase phosphorylating (EC 1.2.1.12); Human parasite; Mono-ADP-ribosylation; Protozoa; NAD+; DTT; dithiothreitol; E-64; trans-Epoxysuccinyl-l-leucylamido(4-guanidino)-butan
Inhibition of telomerase activity by reduction of poly(ADP-ribosyl)ation of TERT and TEP1/TP1 expression in HeLa cells with knocked down poly(ADP-ribose) polymerase-1 (PARP-1) gene
Keywords: NAD +; Poly(ADP-ribosyl)ation; PARP; PAR; TERT; TEP1/TP1; siRNA; HeLa; NAD+; Telomerase
Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation
Keywords: NAD +; glutamate; neurotoxicity; diet; mitochondria; oxidation; stress; ACA; acetoacetate; BHB; β-hydroxybutyrate; DHE; dihydroethidium; EGTA; ethyleneglycol-bis-(β-aminoethyl ether)N,N,Nâ²,Nâ²-tetraacetic acid; FCCP; carbonyl cyanide p-[trifluoromethoxy]-ph
Crystal structure of the yeast nicotinamidase Pnc1p
Keywords: NAD +; Nicotinamidase; Sir2p; X-ray crystallography; Kinetic analyses; NAD+; Multiple isomorphous replacement; Multiwavelength anomalous diffraction
Niacin deficiency delays DNA excision repair and increases spontaneous and nitrosourea-induced chromosomal instability in rat bone marrow
Keywords: NAD +; Niacin; NAD+; Poly(ADP-ribose); Rats; DNA excision repair; Chromosomes; Aberrations; Micronuclei; Comet assay
Overactivation of poly(adenosine phosphate-ribose) polymerase 1 and molecular events in neuronal injury after deep hypothermic circulatory arrest: Study in a rabbit model
Keywords: NAD +; 19; 21; 25; ADP; adenosine diphosphate; ATP; adenosine triphosphate; CPB; cardiopulmonary bypass; DHCA; deep hypothermic circulatory arrest; NAD+; nicotinamide adenine dinucleotide; PAR; Poly(ADP-ribose); PARP-1; poly(adenosine diphosphate-ribose) polym
Spatial and functional relationship between poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in the brain
Keywords: NAD +; NMDA; mitochondria; nucleus; immunostaining; subcellular fractionation; AIF; apoptosis inducing factor; CSS; control salt solution; Cyt C; cytochrome C; GFP; green fluorescent protein; HEK; human embryonic kidney; KO; knockout; MEM; modified Eagle's med
The simultaneous measurement of nicotinamide adenine dinucleotide and related compounds by liquid chromatography/electrospray ionization tandem mass spectrometry
Keywords: NAD +; NAD+; LC/MS/MS; Electrospray ionization
Decreased cADPR and increased NAD+ in the Cd38−/− mouse
Keywords: NAD +; CD38; cADPR; NAD+; ADP-ribosyl cyclase; Pyridine nucleotides; Ca2+ signalling
In-gel activity staining of oxidized nicotinamide adenine dinucleotide kinase by blue native polyacrylamide gel electrophoresis
Keywords: NAD +; NAD+ kinase; BN–PAGE; Activity bands; NAD+; NADP+
Extracellular NAD+ metabolism modulates osteoclastogenesis
Keywords: NAD +; NAD+; Osteoclast; Cyclic ADPribose; ADPribose; NAADP+; Lymphocyte; Metabolism; ADPr; cADPr; NADase; ADPribosyl cyclase
TNF regulates cellular NAD+ metabolism in primary macrophages
Keywords: NAD +; NAD+; TNF; Metabolism; Macrophage; CD38; CD157; IDO; PBEF; NAD+ kinase; ADP-ribosyl cyclase; NAD+ synthase; Murine
Transition state analysis of adenosine nucleosidase from yellow lupin (Lupinus luteus)
Keywords: NAD +; LC/MS; liquid chromatography/mass spectrometry; KIE; kinetic isotope effect; HMDS; hexamethyldisilazine; Tris; tris(hydroxymethyl)aminomethane; SIM; selective ion monitoring; BEBOVIB; bond energy bond order vibrational analysis; RNA; ribonucleic acid; NAD
Preparation and characterization of CePtCl6 films and their electrocatalytic properties with NAD+, l-cystine and sulfur oxoanions
Keywords: NAD +; Cerium hexachloroplatinate; Film modified electrode; EQCM; Electrocatalysis; NAD+
Caffeine metabolites are inhibitors of the nuclear enzyme poly(ADP-ribose)polymerase-1 at physiological concentrations
Keywords: NAD +; Poly(ADP-ribose)polymerase-1; Oxidative stress; NAD+; Necrosis; Methylxanthines; Inhibition
Discovery of quinazolinone and quinoxaline derivatives as potent and selective poly(ADP-ribose) polymerase-1/2 inhibitors
Keywords: NAD +; PARP-1; Poly(ADP-ribose) polymerase-1; PARP-2; Poly(ADP-ribose) polymerase-2 (PARP-2); NAD+; nicotinamide adenine dinucleotide; PAR; Poly(ADP-ribose); NI site; nicotinamide-ribose binding site; AD site; adenine-ribose binding site; Poly(ADP-ribose) polyme
Theophylline prevents NAD+ depletion via PARP-1 inhibition in human pulmonary epithelial cells
Keywords: NAD +; Oxidative stress; Inflammation; Poly(ADP-ribose)polymerase-1; NAD+; COPD; Histone deacetylase; Skeletal muscle breakdown;
Decoding Tat: the biology of HIV Tat posttranslational modifications
Keywords: NAD +; HIV; Tat; Posttranslational modification; CDK9; cyclin-dependent kinase 9; GCN5; general control of amino acid synthesis 5; NAD+; nicotinamide adenine dinucleotide; nuc-1; nucleosome 1 located immediately downstream of the start of transcription at the HI
Key NAD+-binding residues in human 15-hydroxyprostaglandin dehydrogenase
Keywords: NAD +; Prostaglandins; Prostaglandin dehydrogenase; Lipoxins; NAD+;
Xylitol production from sugarcane bagasse hydrolysate
Keywords: NAD +; Ac; acetate; ATP; adenosine triphosphate; EtOH; ethanol; 'H2'; reducing equivalents; NAD+; nicotinamide adenin dinucleotide; NADP+; nicotinamide adenin dinucleotide phosphate; NADPH; reduced nicotinamide adenin dinucleotide phosphate; SBHH; sugarcane
Gold nanoparticles: Catalyst for the oxidation of NADH to NAD+
Keywords: NAD +; Gold nanoparticles; Catalyst; Oxidation; NADH; NAD+;
Stereospecificity of hydride transfer in NAD+-catalyzed 2-deoxy-scyllo-inosose synthase, the key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminocyclitol antibiotics
Keywords: NAD +; 2-Deoxy-scyllo-inosose synthase; NAD+; Stereospecificity; Hydride transfer; Aminocyclitol antibiotics;
Crystal structure of heterotetrameric sarcosine oxidase from Corynebacterium sp. U-96
Keywords: NAD +; Crystal structure; Flavoenzyme; Heterotetramer; Sarcosine oxidase; Cofactor binding; FAD; FMN; Folinic acid; NAD+; Zinc finger;
Understanding human 15-hydroxyprostaglandin dehydrogenase binding with NAD+ and PGE2 by homology modeling, docking and molecular dynamics simulation
Keywords: NAD +; 15-Hydroxyprostaglandin dehydrogenase; NAD+; PGE2; Molecular modeling; Molecular dynamics;
Role of poly(ADP-ribose) glycohydrolase (PARG) in shock, ischemia and reperfusion
Keywords: NAD +; ADP-HPD; ADP-(hydroxymethyl)pyrrolidinediol; ARF; acute renal failure; AST; aspartate aminotransferase; ATP; adenosine triphosphate; ICAM-1; intercellular adhesion molecules; IL-1; interleukin-1; IL-6; interleukin-6; I-R; ischemia-reperfusion; MCAO; m
The electrochemical self-assembly of the FAD modified zinc oxide films and their electrocatalytic properties
Keywords: NAD +; FAD; Zinc oxide; Film modified electrodes; Electrocatalysis; NAD+;
Analysis of ligation and DNA binding by Escherichia coli DNA ligase (LigA)
Keywords: NAD +; BRCT domain; DNA ligase; Ligation; NAD+; Protein-DNA binding;
Redox properties of the lipocalin α1-microglobulin: Reduction of cytochrome c, hemoglobin, and free iron
Keywords: NAD +; α1m; α1-microglobulin; C34S-α1m; α1-microglobulin mutated at amino acid position 34; K(3)T-α1m; α1-microglobulin mutated at amino acid positions 92, 118, and 130; t-α1m; truncated α1-microglobulin without C-terminal tetrapeptide LIPR; EDTA; ethyle
Influence of chronological aging on the survival and nucleotide content of Saccharomyces cerevisiae cells grown in different conditions: occurrence of a high concentration of UDP-N-acetylglucosamine in stationary cells grown in 2% glucose
Keywords: NAD +; Aging; ATP; NAD+; Saccharomyces cerevisiae; UDP-N-acetylglucosamine; Viability;
Characterization of iron hexachloroplatinate films and their electrocatalytic properties with NAD+, hemoglobin and O2
Keywords: NAD +; Iron hexachloroplatinate; Film; EQCM; NAD+; Hemoglobin; Electrocatalysis;
Brain mitochondrial injury induced by oxidative stress-related events is prevented by tamoxifen
Keywords: NAD +; Brain; Mitochondria; Neuroprotection; Oxidative stress; Tamoxifen; CsA; cyclosporin A; ÎΨm; mitochondrial transmembrane potential; GSH; reduced glutathione; GSSG; oxidized glutathione; MPP+; 1-methyl-4-phenyl-pyridinium ion; MPT; mitochondrial permeabil
Brain, aging and neurodegeneration: Role of zinc ion availability
Keywords: NAD +; [Ca++]i; intracellular Ca++ concentration; [Zn++]b; zinc concentration in the blood; [Zn++]e; extracellular free zinc ion concentration; [Zn++]i; intracellular free zinc ion concentration; [Zn++]s; synaptic zinc; Aβ; amyloid beta-peptide; AD; Alzheimer d
New insights on brain stem death: From bedside to bench
Keywords: NAD +; AIF; apoptosis-inducing factor; ANG II; angiotensin II; AT1R; angiotensin subtype 1 receptor; AT2R; angiotensin subtype 2 receptor; CCO; cytochrome c oxidase; CoQ10; coenzyme Q10; ÎΨm; mitochondrial electrochemical gradient; eNOS; endothelial nitric oxi