دانلود مقالات ISI درباره NEC-1 + ترجمه فارسی

افزایش فعالیت سیتوتوکسیک دکسوروبیسین از طریق مهار اتوفایگی در رده سلول های سرطانی سه گانه منفرد

Enhanced cytotoxic activity of doxorubicin through the inhibition of autophagy in triple negative breast cancer cell line

Keywords: NEC-1; TNBC; triple negative breast cancer; ROS; reactive oxygen species; H2DCFDA; 2′,7′-dichlorodihydrofluorescein diacetate; MTT; 3-[4,5-dimethyl-2-thiazolyl]-2,5-diphenyl-2H-tetrazolium bromide; CI value; combination index value; DXR; doxorubicin; 3-MA; 3

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

هنگامیکه فعال شدن کاسپاز مسدود می شود، سلول های سرطانی اسمک باعث ایجاد نروپتوز در سلول های کارسینوم پانکراس می شوند.

Smac mimetic triggers necroptosis in pancreatic carcinoma cells when caspase activation is blocked

Keywords: NEC-1; Necroptosis; Smac mimetic; Cell death; Pancreatic carcinoma; IAP proteins; cIAP; cellular IAP; FADD; Fas-associated protein with death domain; FCS; fetal calf serum; GAPDH; anti-glyceraldehyde 3-phosphate dehydrogenase; IAP; inhibitor of apoptosis; MLKL;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

اسموتیک و اسید اولئانولیک همکاری می کنند تا باعث مرگ سلولی در سلول های کارسینوم سلول های هپاتوسلولار انسان شوند

Smac mimetic and oleanolic acid synergize to induce cell death in human hepatocellular carcinoma cells

Keywords: NEC-1; AIF; apoptosis-inducing factor; BSO; Buthionine sulfoximine; CAM; chorioallantoic membrane; cIAP; cellular inhibitor of apoptosis; DR5; death receptor-5; ENDOG; endonuclease G; ER; endoplasmatic reticulum; FCS; fetal calf serum; HBV; hepatitis B virus; HC

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

مشارکت استرسهای اندوپلاسمی رتیکولوم در نروپتوزیس میکروگلای / ماکروفاژ پس از آسیب نخاعی

Involvement of endoplasmic reticulum stress in the necroptosis of microglia/macrophages after spinal cord injury

Keywords: NEC-1; 4-PBA; 4-phenylbutyrate; CC3; cleaved Caspase-3; CXCR4; chemokine (C-X-C motif) receptor 4; DMEM; Dulbecco's modified Eagle medium; EDTA; ethylenediaminetetraacetic acid; EM; electronic microscopic; ER; endoplasmic reticulum; FBS; fetal bovine serum; GR

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

مکانیزم های مولکولی نکروز تنظیم شده

Molecular mechanisms of regulated necrosis

Keywords: NEC-1; AIF; apoptosis-inducing factor; ANT; adenine nucleotide translocase; CsA; cyclosporin A; CYPD; cyclophilin D; Δψm; mitochondrial transmembrane potential; Fer-1; ferrostatin-1; MAMP; microbe-associated molecular pattern; MLKL; mixed lineage kinase domain

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

شیکونین موجب کاهش مرگ و میر ناشی از نکروز شده توسط پروتئین 1 و 3 پیچیده

Shikonin induces programmed necrosis-like cell death through the formation of receptor interacting protein 1 and 3 complex

Keywords: NEC-1; RIP1; receptor interacting protein 1; RIP3; receptor interacting protein3; SKN; shikonin; TNFα; tumor necrosis factor alpha; ROS; reactive oxygen species; Nec-1; necrostatin-1; zVAD; benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone; Shikonin; Progr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Necroptosis in 3-chloro-1, 2-propanediol (3-MCPD)-dipalmitate-induced acute kidney injury in vivo and its repression by miR-223-3p

Keywords: NEC-1; 3-MCPD; 3-chloro-1,2-propanediol; 3′UTR; 3′ un-translated region; AKI; acute kidney injury; BMD10; Benchmark doses; BMDL10; BMD Lower Confidence Limit; BW; body weight; CXCl; chemokine (C-X-C motif) ligand; DE; differentially expressed; DR6; death rec

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

RIP1K Contributes to Neuronal and Astrocytic Cell Death in Ischemic Stroke via Activating Autophagic-lysosomal Pathway

Keywords: NEC-1; 3-MA; 3-methyladenine; AO; Acridine Orange; DMEM; Dulbecco's Modified Eagle's Medium; GFAP; glial fibrillary acidic protein; HRP; horseradish peroxidase; LC3 II; light chain 3 II; LDH; lactate dehydrogenase; LMP; lysosomal membrane permeability; MAP2; mic

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

High-mobility group box 1 protein-mediated necroptosis contributes to dasatinib-induced cardiotoxicity

Keywords: NEC-1; HMGB1; high mobility group box 1; CML; chronic myelogenous leukemia; Ph+ALL; Philadelphia chromosome positive acute lymphoblastic leukemia; RIP1; receptor-interacting protein kinase 1; RIP3; receptor-interacting protein kinase 3; MLKL; mixed lineage kinas

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Extracellular acidification induces ROS- and mPTP-mediated death in HEK293 cells

Keywords: NEC-1; Δψ; mitochondrial membrane potential; AA; antimycin A; CI; complex I or NADH:Ubiquinone oxidoreductase; CIII; complex III or Ubiquinol-cytochrome c oxidoreductase; CsA; cyclosporin A; ETC; electron transport chain; Fer-1; ferrostatin-1; HEt; hydroethidi

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Neuroprotective Effects of DTIO, A Novel Analog of Nec-1, in Acute and Chronic Stages After Ischemic Stroke

Keywords: NEC-1; BSA; bovine serum albumin; CBF; cerebral blood flow; CSPGs; chondroitin sulfate proteoglycans; DTIO; 5-(3′,5′-dimethoxybenzal)-2-thio-imidazole-4-ketone; ELISA; enzyme-linked immunosorbent assay; GFAP; glial fibrillary acidic protein; HT22; hippocampa

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

Necrostatin-1 protects hippocampal neurons against ischemia/reperfusion injury via the RIP3/DAXX signaling pathway in rats

Keywords: NEC-1; I/R; ischemia/reperfusion; RIP3; receptor-interacting protein 3; DAXX; death-associated protein; Nec-1; necrostatin-1; HE; hematoxylin and eosin; PML-NBs; promyelocytic leukemia protein-nuclear bodies; FADD; fas-associated with death domain protein; DMSO;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

A novel RIPK1 inhibitor that prevents retinal degeneration in a rat glaucoma model

Keywords: NEC-1; CH; chemical hypoxia; CHX; cycloheximide; Cpd27; compound 27; DAPI; 4,6-diamidino-2-phenylindole; GCL; ganglion cell layer; H2O2; hydrogen peroxide; MNNG; 1-methyl-3-nitro-1 nitrosoguanidine; Nec-1; necrostatin-1; OGD; oxygen glucose deprivation; PI; prop

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Tert-butyl hydroperoxide (t-BHP) induced apoptosis and necroptosis in endothelial cells: Roles of NOX4 and mitochondrion

Keywords: NEC-1; AA; Antimycin A; ALL; Allopurinol; ASK1; Apoptosis-signaling kinase 1; DCFH2-DA; 5-(6)-carboxy-2′, 7′-dichlorodihydrofluorescein diacetate; DPI; Diphenyleneiodonium; ERK; Extracellular signal regulated kinase; H2O2; Hydrogen peroxide; JNK; c-Jun-N-ter

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Cisplatin-induced necroptosis in TNFα dependent and independent pathways

Keywords: NEC-1; RIP; receptor-interacting protein; MLKL; mixed lineage kinase domain-like protein; CypD; cyclophilin-D; ROS; reactive oxygen species; mPTP; mitochondrial permeability transition pore; TNFα; tumor necrosis factor α; CaMKII; Ca2 +-calmodulin-dependent pr

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Adhesion-induced eosinophil cytolysis requires the receptor-interacting protein kinase 3 (RIPK3)-mixed lineage kinase-like (MLKL) signaling pathway, which is counterregulated by autophagy

Keywords: NEC-1; Autophagy; eosinophil cytolysis; eosinophilic disease; necrosis; necroptosis; non-apoptotic cell death; mixed lineage kinase-like; RIP kinase; reactive oxygen species; cfeg; Cluster of free eosinophil granules; CR3; Complement receptor 3; DPI; Diphenylene

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2017 سفارش ترجمه

Inhibitions of mTORC1 and 4EBP-1 are key events orchestrated by Rottlerin in SK-Mel-28 cell killing

Keywords: NEC-1; Rottlerin; AMPK; mTOR; 4EBP-1; Autophagy; Protein synthesis; RPMI; Roswell Park Memorial Institute (RPMI); Becl-1; beclin-1; AMPK; AMP-activated protein kinase; ACC; acetyl-CoA carboxylase; mTOR; mammalian target of rapamycin; raptor; regulatory-associate

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

MLKL inhibition attenuates hypoxia-ischemia induced neuronal damage in developing brain

Keywords: NEC-1; ANOVA; analysis of variance; BHA; butylated hydroxyanisole; CCA; common carotid artery; Drp1; dynamin-related protein-1; HI; hypoxia-ischemia; MLKL; mixed lineage kinase domain-like protein; NAC; N-acetylcysteine; Nec-1; necrostatin 1; NSS; neurological s

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2016 سفارش ترجمه

Necroptosis: an alternative cell death program defending against cancer

Keywords: NEC-1; AIF; apoptosis-inducing factor; ALL; acute lymphoblastic leukemia; cIAP; cellular inhibitor of apoptosis protein; CLL; chronic lymphocytic leukemia; CYLD; cylindromatosis; DAMPs; Damage Associated Molecular Patterns; DCs; dendritic cells; Drp1; dynamin-re

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2016 سفارش ترجمه

Diarachidonoylphosphoethanolamine induces necrosis/necroptosis of malignant pleural mesothelioma cells

Keywords: NEC-1; DAPE; 1,2-diarachidonoyl-sn-glycero-3-phosphoethanolamine; MPM; malignant pleural mesothelioma; PI; propidium iodide; AV; annexin V; Nec-1; necrostatin-1; ROS; reactive oxygen species; MPT; mitochondrial permeability transition; CypD; cyclophilin D; CsA;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

24(S)-Hydroxycholesterol induces RIPK1-dependent but MLKL-independent cell death in the absence of caspase-8

Keywords: NEC-1; 24S-OHC; 24(S)-hydroxycholesterol; ACAT1; acyl-CoA:cholesterol acyltransferase 1; AD; Alzheimer's disease; cIAP; cellular inhibitor of apoptosis protein; CYP46A1; cholesterol 24-hydroxylase; JurkatCas8−/−; caspase-8-deficient Jurkat; LDH; lactate de

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of a novel synergistic induction of cell death by Smac mimetic and HDAC inhibitors in acute myeloid leukemia cells

Keywords: NEC-1; Apoptosis; Smac; Leukemia; Necroptosis; AML; acute myeloid leukemia; CI; combination index; cIAP; cellular inhibitor of apoptosis protein; FACS; fluorescence-activated cell-sorting analysis; FCS; fetal calf serum; FLT3; Fms-like tyrosine kinase 3; FSC/SSC

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2015 سفارش ترجمه

The role of RIP3 mediated necroptosis in ouabain-induced spiral ganglion neurons injuries

Keywords: NEC-1; SGN; spiral ganglion neuron; RIP3; receptor-interacting protein 3; Nec-1; necrostatin-1; ABR; auditory brain-stem response; Z-VAD; N-benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone; Spiral ganglion neuron injury; Ouabain; Necroptosis; Nec-1; RIP3; Z-VAD;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Ischemic insults induce necroptotic cell death in hippocampal neurons through the up-regulation of endogenous RIP3

Keywords: NEC-1; Actb; β-Actin; cIAP; Cellular Inhibitor of Apoptosis Protein; Ctx; Cortex; CYLD; Cylindromatosis; DG; Dentate Gyrus; DISC; Death Inducing Signaling Complex; DR; Death Receptor; FADD; Fas-associated Protein with Death Domain; Gapdh; Glyceraldehyde 3-phosp

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Sexual dimorphism in BDNF signaling after neonatal hypoxia-ischemia and treatment with necrostatin-1

Keywords: NEC-1; ANOVA; analysis of variance; BDNF; brain-derived neurotrophic factor; E2; estradiol; ELISA; enzyme-linked immunosorbent assay; ER; estrogen receptor; ERE; estrogen response element; FL.TrkB; full-length TrkB; HI; hypoxia-ischemia; nec-1; necrostatin-1;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Sorafenib overcomes the chemoresistance in HBx-expressing hepatocellular carcinoma cells through down-regulation of HBx protein stability and suppresses HBV gene expression

Keywords: NEC-1; 3-MA; 3-methyladenine; AIF; apoptosis-inducing factor; BAF; Bafilomycin A1; CQ; Chloroquine; HBV; Hepatitis B virus; HBx; Hepatitis B virus X; HCC; Hepatocellular carcinoma; IFNα; interferon alpha; LC3II; dynein light chain 3; MMP; mitochondrial membrane

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2014 سفارش ترجمه

Critical contribution of oxidative stress to TNFα-induced necroptosis downstream of RIPK1 activation

Keywords: NEC-1; BHA; butylated hydroxyanisole; cIAP1; cellular inhibitor of apoptosis protein-1; FADD; Fas-associated protein with death domain; Nec-1; necrostatin-1; RIPK1; receptor-interacting serine-threonine kinase 1; TNF; tumor necrosis factor; TRADD; TNF receptor

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Knockdown of FAM3B triggers cell apoptosis through p53-dependent pathway

Keywords: NEC-1; Bak; Bcl-2 antagonist/killer; Bax; Bcl-2-associated X protein; FADD; Fas-associated death domain; FAM3B; family with sequence similarity 3, member B; LDH; lactate dehydrogenase; MTT; 3-(4,5-cimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide; Nec-1; ne

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه