Keywords: نپریلین; Neprilysin; Zinc metalloprotease; Protein structure; Crystallography; Substrate-free;
مقالات ISI نپریلین (ترجمه نشده)
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Keywords: نپریلین; Gene expression; Immunolocalisation; Periodontitis; Alzheimer's disease; Amyloid beta precursor protein; Neprilysin;
Keywords: نپریلین; Panagrolaimus davidi; Antarctic; Nematode; Intracellular freezing; Neprilysin; Leucine-rich repeat;
Keywords: نپریلین; Amyloid-beta; Heart failure; Cognition; Prognosis; Biomarkers; Amiloide-beta; Insuficiencia cardiaca; Cognición; Pronóstico; Biomarcadores; Aβ40; amyloid-beta 1-40 peptide; CV; cardiovascular; eGFR; estimated glomerular filtration rate; HF; heart failu
Keywords: نپریلین; renin-angiotensin system; heart transplantation; angiotensin-converting-enzyme; angiotensin-converting-enzyme inhibitors; chymase; neprilysin; prolyl-carboxypeptidase;
Keywords: نپریلین; angiotensin-converting enzyme inhibitor; angiotensin receptor blocker; heart failure; neprilysin; sacubitril/valsartan;
Keywords: نپریلین; Heart failure therapies; Funny channel; Neprilysin; Sacubitril/valsartan; Ivabradine
Keywords: نپریلین; designer natriuretic peptide; drug development; heart failure; hypertension; natriuretic peptide; ANP; A-type natriuretic peptide; AS-BNP; alternatively spliced variant of BNP; BNP; B-type natriuretic peptide; BP; blood pressure; CD-NP; cenderitide; cGMP;
Keywords: نپریلین; HIBM; hereditary inclusion-body myopathy; s-IBM; sporadic inclusion-body myositis; GNE; UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; GNE/MNK; UDP-GlcNAc 2-epimerase/ManNAc kinase; DMRV; distal myopathy with rimmed vacuoles; CK; creatine
Keywords: نپریلین; Kidney; Stem cells; Regenerative medicine; Bcl2; B-cell lymphoma 2; CD10; neprilysin; CD15; 3-fucosyl-N-acetyl-lactosamine; CD133; prominin 1; CKD; chronic kidney disease; CK7; cytokeratin 7; CK8-18; cytokeratin 8-18; EMA (MUC1); anti-endomysial (mucin 1)
Keywords: نپریلین; Neprilysin; Polymorphism; β-Amyloid; Alzheimer's disease; Meta-analysis; Risk;
Keywords: نپریلین; Complex regional pain syndrome; Endothelin-1; Neprilysin; Nerve injury; Neutral endopeptidase;
Keywords: نپریلین; Neprilysin; Natriuretic peptide; RAAS; Hypertension; Heart failure;
Keywords: نپریلین; Kynurenic acid; Neprilysin; Aβ peptides; Alzheimer's disease; Neuroprotection; SH-SY5Y neuroblastoma cells; Primary neuronal cells; KYNA; kynurenic acid; NEP; neprilysin; 7-chloroKYNA; 7-chlorokynurenic acid; 5, 7-dichloroKYNA; 5, 7-dichlorokynurenic aci
Keywords: نپریلین; Amyloid precursor protein; APP intracellular domain (AICD); Histone deacetylase; Hypoxia; Mediator; Neprilysin;
Apelin, a promising target for Alzheimer disease prevention and treatment
Keywords: نپریلین; Alzheimer disease; Apelin; Amyloid beta; Central nervous system; Oxidative stress; AAA; Abdominal aortic aneurysm; ABCA1; ATP-binding cassette transporter A1; ACE; Angiotensin converting enzyme; ACh; Acetylcholine; AChE; Acetyl choline esterase; AD; Alzhe
Neprilysin inhibition and endothelin-1 elevation: Focus on the kidney
Keywords: نپریلین; Neprilysin; Thiorphan; Sacubitril; Endothelin-1; Atrial natriuretic peptide;
Chronic intermittent hypoxia induces changes on the expression and activity of neprilysin (EC 3.4.24.11) in the brain of rats
Keywords: نپریلین; Obstructive sleep apnea; Hypoxia; AlzheimeÅs disease; Neprilysin;
Protective effects of curcumin on acrolein-induced neurotoxicity in HT22 mouse hippocampal cells
Keywords: نپریلین; AD; Alzheimer disease; A; amyloid-beta peptide; ADAM-10; A-disintegrin and metalloprotease 10; APP; amyloid precursor protein; GFAP; glial fibrillary acidic protein; MAPK; mitogen-activated protein kinase; MDA; malondialdehyde; MWM; Morris water maze; NEP
Insulin-signaling Pathway Regulates the Degradation of Amyloid β-protein via Astrocytes
Keywords: نپریلین; ACE; angiotensin-converting enzyme; AD; Alzheimer's disease; AÃ; amyloid Ã-protein; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; ECE; endothelin-converting enzyme; EDTA; ethylenediaminetetraacetic acid; EGCG; epigallocatechi
Microglia-derived extracellular vesicles in Alzheimer's Disease: A double-edged sword
Keywords: نپریلین; AD; Alzheimer's Diseases; APP; Amyloid Precursor Protein; Aβ; amyloid; Bcl-2; B-cell lymphoma 2; BBB; blood brain barrier; BMECs; brain microvascular endothelial cells; CNS; central nervous system; CSF; cerebrospinal fluid; EVs; extracellular vesicles;
Substituted α-mercaptoketones, new types of specific neprilysin inhibitors
Keywords: نپریلین; BTFA; boron trifluoroacetate; DIEA; diisopropylethylamine; EtOH; ethanol; HPLC; High Performance Liquid Chromatography; LC/MS; Liquid Chromatography/Mass Spectroscopy; LDA; lithium diisopropyl amide; NEP; neprilysin; NMM; N-methylmorpholine; PMBSH; para-m
Neprilysin inhibitors: A new hope to halt the diabetic cardiovascular and renal complications?
Keywords: نپریلین; ARBs; Ang II receptor blockers; AT2R; Ang II type 2 receptors; AT1R; Ang II type 1 receptors; Ang II; angiotensin II; ARNi; angiotensin receptor neprilysin inhibitors; ACE; angiotensin-converting enzyme; ANP; atrial natriuretic peptide; BNP; B-type natriu
Rebamipide reduces amyloid-β 1-42 (Aβ42) production and ameliorates Aβ43-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells
Keywords: نپریلین; Aβ; amyloid-beta; AD; Alzheimer's disease; ADAM; a disintegrin and metalloproteinase; APP; amyloid precursor protein; ASPD; amylospheroids; BCA; bicinchoninic acid; BACE1; β-site APP-cleaving enzyme-1; BDNF; brain-derived neurotrophic factor; BSA; bov
Synergistic combinations of the dual enkephalinase inhibitor PL265 given orally with various analgesic compounds acting on different targets, in a murine model of cancer-induced bone pain
Keywords: نپریلین; ACEA; arachidonyl-2â²-chloroethylamide; AEA; N-arachidonoylethanolamide, anandamide; APN; aminopeptidase N; BNI; nor-binaltorphimine; CCI; chronic constrictive injury; CYP; cyprodime; DENKI; dual enkephalinase inhibitor; DOR; delta opioid receptor; ENK;
Putting Together the Pieces of the Natriuretic Peptide Puzzleâ
Keywords: نپریلین; biomarkers; brain natriuretic peptide; corin; heart failure; neprilysin;
Monitoring B-type natriuretic peptide in patients undergoing therapy with neprilysin inhibitors. An emerging challenge?
Keywords: نپریلین; Heart failure; B-type natriuretic peptide; BNP; Neprilysin;
Neprilysin Inhibition in the Time of Precision Medicineâ
Keywords: نپریلین; age-related macular degeneration; Alzheimer's disease; angiotensin-converting enzyme inhibitor; heart failure; neprilysin;
A Test in Context: Critical Evaluation of Natriuretic Peptide Testing in Heart Failure
Keywords: نپریلین; biological markers; BNP; neprilysin; NT-proBNP; ACC/AHA; American College of Cardiology/American Heart Association; ANP; atrial natriuretic peptide; BNP; B-type natriuretic peptide; HF; heart failure; NT-proBNP; N-terminal pro-B-type natriuretic peptide
Influence of Sacubitril/Valsartan (LCZ696) on 30-Day Readmission After Heart Failure Hospitalization
Keywords: نپریلین; hospitalization; neprilysin; readmission; sacubitril/valsartan; CEC; Clinical Endpoints Committee; CI; confidence interval; HF; heart failure; LCZ696; sacubitril/valsartan; OR; odds ratio;
Characterization of insulin-degrading enzyme-mediated cleavage of Aβ in distinct aggregation states
Keywords: نپریلین; Amyloid-beta; Insulin-degrading enzyme; Neprilysin; Alzheimer's disease; Aggregation; Aβ cleavage;
Major amyloid-β-degrading enzymes, endothelin-converting enzyme-2 and neprilysin, are expressed by distinct populations of GABAergic interneurons in hippocampus and neocortex
Keywords: نپریلین; Alzheimer's disease; Aβ degradation; Endothelin-converting enzyme; GABA; Interneuron; Neprilysin; Somatostatin; Parvalbumin;
Preventive and alleviative effects of the dual enkephalinase inhibitor (Denki) PL265 in a murine model of neuropathic pain
Keywords: نپریلین; APN; Aminopeptidase N; BBB; blood-brain barrier; CCI; Chronic constrictive injury; DENKI; Dual ENKephalinase Inhibitor; DOP; delta opioid receptor; DRG; Dorsal Rood Ganglion; i.c.v.; intracerebroventricular; MOP; mu opioid receptor; NEP; Neprilysin; PKC;
Multiple mechanisms of age-dependent accumulation of amyloid beta protein in rat brain: Prevention by dietary supplementation with N-acetylcysteine, α-lipoic acid and α-tocopherol
Keywords: نپریلین; Amyloid precursor protein; β Secretase; Neprilysin; Amyloid beta protein; Alzheimer's disease; Antioxidant;
Neprilysin in Heart Failure
Keywords: نپریلین; BNP; heart failure; neprilysin; physiology;
Prognostic Value and Kinetics of Soluble Neprilysin in Acute Heart Failure : A Pilot Study
Keywords: نپریلین; acute heart failure; neprilysin; prognosisAHF, acute heart failure; ARNi, angiotensin receptor neprilysin inhibitor; CV, cardiovascular; HF, heart failure; LVEF, left ventricular ejection fraction; NEP, neprilysin; NT-proBNP, N-terminal prohormone of brai
Amyloid beta-42 (Aβ-42), neprilysin and cytokine levels. A pilot study in patients with HIV related cognitive impairments
Keywords: نپریلین; Amyloid beta-42; Neprilysin; Pro-inflammatory cytokines; Anti-inflammatory cytokines; HIV associated neurocognitive disorders; HIV related cognitive impairments
Elevated Plasma B-Type Natriuretic Peptide Concentrations Directly Inhibit Circulating Neprilysin Activity in Heart Failure
Keywords: نپریلین; BNP; BNP-mediated neprilysin inhibition; heart failure; neprilysin; substance PADHF, acute decompensated heart failure; ANP, A-type natriuretic peptide; ARNi, angiotensin receptor-neprilysin inhibitor; BNP, B-type natriuretic peptide; CHF, chronic heart f
An Aβ42 uptake and degradation via Rg3 requires an activation of caveolin, clathrin and Aβ-degrading enzymes in microglia
Keywords: نپریلین; Rg3; Aβ42; Macrophage scavenger receptor class A; Endocytosis; Neprilysin; Insulin degrading enzyme;
Estrategia multimarcador para estratificar el pronóstico en insuficiencia cardiaca. Valor de los marcadores neurohumorales: neprilisina frente a NT-proBNP
Keywords: نپریلین; Insuficiencia cardiaca; Neprilisina; NT-proBNP; Pronóstico; SupervivenciaHeart failure; Neprilysin; NT-proBNP; Prognosis; SurvivalCV, cardiovascular; hsTnT, troponina T de alta sensibilidad; IC, insuficiencia cardiaca; NT-proBNP, fracción aminoterminal de
Multimarker Strategy for Heart Failure Prognostication. Value of Neurohormonal Biomarkers: Neprilysin vs NT-proBNP
Keywords: نپریلین; Heart failure; Neprilysin; NT-proBNP; Prognosis; SurvivalInsuficiencia cardiaca; Neprilisina; NT-proBNP; Pronóstico; SupervivenciaCV, cardiovascular; HF, heart failure; hsTnT, high-sensitivity troponin T; NT-proBNP, N-terminal pro-B-type natriuretic pepti
Reduction of amyloid-beta levels in mouse eye tissues by intra-vitreally delivered neprilysin
Keywords: نپریلین; Amyloid-beta; Neprilysin; Intra-vitreal injection; C57BL/6J mouse; 5XFAD mouse; Electroretinogram; Aβ; amyloid-beta; NEP; neprilysin; sNEP; soluble catalytic domain of neprilysin; PA; phosphoramidon; ERG; electroretinogram; PBS; phosphate-buffered saline
Extra-virgin olive oil attenuates amyloid-β and tau pathologies in the brains of TgSwDI mice
Keywords: نپریلین; AD; Alzheimer's disease; Aβ; amyloid-β; APP; amyloid-β precursor protein; BBB; blood-brain barrier; BCI; brain clearance index; CAA; cerebral amyloid angiopathy; DEA; diethylamine; EVOO; extra-virgin olive oil; FA; formic acid; IDE; insulin degradi
Production of soluble Neprilysin by endothelial cells
Keywords: نپریلین; QFS; quenched fluorescent substrate; NEP; Neprilysin; CALLA; common acute lymphoblastic leukemia antigen; ADAM-17; A Disintegrin and Metalloprotease 17; ADAM; Endothelial cell; Enzymes; Exosomes; Shedding;
Combined Neprilysin and Renin-Angiotensin System Inhibition for the Treatment of Heart Failure
Keywords: نپریلین; heart failure; natriuretic peptide; neprilysin; ACE; angiotensin-converting enzyme; ANP; atrial natriuretic peptide; BNP; brain (or B-type) natriuretic peptide; CI; confidence interval; CNP; C-type natriuretic peptide; HFpEF; heart failure with preserved
Natriuretic peptides and cardio-renal disease
Keywords: نپریلین; Chronic kidney disease; Heart failure; Hypertension; Natriuretic peptide; Neprilysin;
Study on Aβ34 biology and detection in transgenic mice brains
Keywords: نپریلین; Alzheimer's disease; Aβ34; Polyclonal; Degradation; Neprilysin; Apoptosis; HEK cells; 3xTg mice; Human brain;
Prediabetes-induced vascular alterations exacerbate central pathology in APPswe/PS1dE9 mice
Keywords: نپریلین; Alzheimer's disease; Prediabetes; Hyperinsulinemia; Amyloid-β; Tau; Microglia; Insulin degrading enzyme; Neprilysin; Haemorrhage
Green tea catechin leads to global improvement among Alzheimer's disease-related phenotypes in NSE/hAPP-C105 Tg mice
Keywords: نپریلین; Catechin; Aβ-42; γ-Secretase; MAPK; Neprilysin; Pin1;
ReviewInvolvement of the opioid and cannabinoid systems in pain control: New insights from knockout studies
Keywords: نپریلین; Opioid receptor; Cannabinoid receptor; Fatty-acid amide hydrolase; Monoacylglycerol lipase; Neprilysin; Tolerance;