MicroRNAs underlying memory deficits in neurodegenerative disorders
Keywords: اختلالات نوروژنیک; Neurodegenerative disorders; Dementia; miR-132; miR-124; miR-34;
مقالات ISI اختلالات نوروژنیک (ترجمه نشده)
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Synthesis and in vitro evaluation of new fluorinated quinoline derivatives with high affinity for PDE5: Towards the development of new PET neuroimaging probes
Keywords: اختلالات نوروژنیک; Quinoline; Fluorination; Phosphodiesterase 5; Radiotracer; Positron emission tomography; AD; alzheimer's disease; AllocCl; allyl chloroformate; ATR; attenuated total reflectance; cAMP; cyclic adenosine 3â²,5â²-monophosphate; cGMP; cyclic guanosine 3â²,
Synthesis and structure-activity relationship study of novel 3-heteroarylcoumarins based on pyridazine scaffold as selective MAO-B inhibitors
Keywords: اختلالات نوروژنیک; Coumarin; Pyridazine; MAO-B; Neurodegenerative disorders; Molecular modeling; ADME;
Targeting chaperones, heat shock factor-1, and unfolded protein response: Promising therapeutic approaches for neurodegenerative disorders
Keywords: اختلالات نوروژنیک; 17-AAG; 17-(allylamino)-17-demethoxygeldanamycin (tanespimycin); 17-DMAG; 17- dimethylaminoethylamino-17-demethoxygeldanamycin (alvespimycin); AAV; adeno-associated virus; Aβ; amyloid-β; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP;
REM sleep Behaviour Disorder
Keywords: اختلالات نوروژنیک; RBD; Neurodegenerative disorders; Sleep; Treatment; Neurophysiology;
Pharmacological induction of hemeoxygenase-1 activity attenuates intracerebroventricular streptozotocin induced neurocognitive deficit and oxidative stress in rats
Keywords: اختلالات نوروژنیک; Alzheimer's disease; Cognitive dysfunction; Oxidative stress; Hemeoxygenase-1; Dementia; Neurodegenerative disorders;
The use of chemometrics to study multifunctional indole alkaloids from Psychotria nemorosa (Palicourea comb. nov.). Part II: Indication of peaks related to the inhibition of butyrylcholinesterase and monoamine oxidase-A
Keywords: اختلالات نوروژنیک; Chromatographic fingerprinting; Multivariate calibration technique; Indole alkaloid; Neurodegenerative disorders; Multifunctional compounds
Dietary and donepezil modulation of mTOR signaling and neuroinflammation in the brain
Keywords: اختلالات نوروژنیک; Brain; Aging; High fat diet; Obesity; Neurodegenerative disorders; mTOR pathway; Donepezil; Neuroinflammation;
Basic NeuroscienceWhat's wrong with my mouse cage? Methodological considerations for modeling lifestyle factors and gene-environment interactions in mice
Keywords: اختلالات نوروژنیک; Environmental modifiers; Gene-environment interactions; Housing conditions; Experience-dependent plasticity; Neurological disease; Psychiatric disorders; Tandem repeat disorders; Polyglutamine disease; Neurodegenerative disorders; Alzheimer's disease; H
Characterizations of a synthetic pituitary adenylate cyclase-activating polypeptide analog displaying potent neuroprotective activity and reduced in vivo cardiovascular side effects in a Parkinson's disease model
Keywords: اختلالات نوروژنیک; Neurodegeneration; Neurodegenerative disorders; PACAP; Dopaminergic neuron survival; SH-SY5Y neuroblastoma cell survival; Vasodilation; Cq; quantification cycle; Eu3; europium(III) cryptate; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3
Drug design, synthesis, in vitro and in silico evaluation of selective monoaminoxidase B inhibitors based on 3-acetyl-2-dichlorophenyl-5-aryl-2,3-dihydro-1,3,4-oxadiazole chemical scaffold
Keywords: اختلالات نوروژنیک; 2,3-Dihydro-1,3,4-oxadiazoles; Neurodegenerative disorders; MAO-B; Docking; Molecular dynamics;
Structure-guided development of dual β2 adrenergic/dopamine D2 receptor agonists
Keywords: اختلالات نوروژنیک; G protein-coupled receptors; Dopamine receptor; β2 adrenergic receptor; Neurodegenerative disorders; Parkinson's disease; Molecular probes; Polypharmacology;
Evaluation of neuron-glia integrity by in vivo proton magnetic resonance spectroscopy: Implications for psychiatric disorders
Keywords: اختلالات نوروژنیک; Neuron-glia integrity; MRS; Neurometabolites; Neurodegenerative disorders; Psychiatric disorders;
Batwing appearance - A neuroradiologic clue to glutaric aciduria-type 1
Keywords: اختلالات نوروژنیک; Inborn errors of metabolism; Neurodegenerative disorders; Basal ganglia diseases;
Current status of neuronal cell xenotransplantation
Keywords: اختلالات نوروژنیک; Neuronal xenotransplantation; Neurons; Pig-to-primate; Neurodegenerative disorders; Stem cells
Assessment of acetylcholinesterase and tyrosinase inhibitory and antioxidant activity of Alchemilla vulgaris and Filipendula ulmaria extracts
Keywords: اختلالات نوروژنیک; Acetylcholinesterase inhibitory activity; Tyrosinase inhibitory activity; Antioxidant activity; Alchemilla vulgaris; Filipendula ulmaria; Neurodegenerative disorders
Identifying Aβ-specific pathogenic mechanisms using a nematode model of Alzheimer's disease
Keywords: اختلالات نوروژنیک; Alzheimer's disease; Neurodegenerative disorders; Neurodegeneration; Beta-amyloid; Dementia;
Identifying bvFTD Within the Wide Spectrum of Late Onset Frontal Lobe Syndrome: A Clinical Approach
Keywords: اختلالات نوروژنیک; bvFTD; frontal lobe syndrome; psychiatry; neurodegenerative disorders; early diagnosis;
Regulation of the adrenoleukodystrophy-related gene (ABCD2): Focus on oxysterols and LXR antagonists
Keywords: اختلالات نوروژنیک; LXR antagonists; Oxysterols; Adrenoleukodystrophy; Peroxisome; ABC transporters; Neurodegenerative disorders;
ReviewmicroRNAs: A connection between cholesterol metabolism and neurodegeneration
Keywords: اختلالات نوروژنیک; miRNAs; Cholesterol metabolism; Neurodegenerative disorders;
C9ORF72 repeat expansion: a genetic mutation associated with Amyotrophic Lateral Sclerosis
Keywords: اختلالات نوروژنیک; C9ORF72; Neurodegenerative disorders; Motor neuron disease;
New insights into the biological properties of Crocus sativus L.: chemical modifications, human monoamine oxidases inhibition and molecular modeling studies
Keywords: اختلالات نوروژنیک; Crocin; Crocus sativus L.; hMAO inhibitors; Depression; Neurodegenerative disorders; Safranal
Screening and identification of neuroprotective compounds relevant to Alzheimer׳s disease from medicinal plants of S. Tomé e PrÃncipe
Keywords: اختلالات نوروژنیک; Aβ; amyloid beta peptide; AD; Alzheimer׳s disease; APP; amyloid precursor protein; ATP; adenosine triphosphate; BBB; blood-brain barrier; CLogP; lipophilicity; CNS; Central nervous system; DMEM; Dulbecco׳s modified Eagle׳s medium; ESI; Electrospray
Cortical EEG oscillations and network connectivity as efficacy indices for assessing drugs with cognition enhancing potential
Keywords: اختلالات نوروژنیک; Cognition enhancers; EEG oscillations; Coherent functional network; Neurodegenerative disorders; Animal model; Translational biomarker;
Astrocyte-neuron interplay in maladaptive plasticity
Keywords: اختلالات نوروژنیک; CNS; central nervous system; GFAP; glial fibrillary acidic protein; gGTs; glial glutamate transporters; EAATs; excitatory amino acid transporters; Reactive gliosis; Neuro-glial network; Neurodegenerative disorders; Neuroinflammatory disorders; Behavioral
Mitochondrial stress extends lifespan in C. elegans through neuronal hormesis
Keywords: اختلالات نوروژنیک; Aging; C. elegans; Chemotaxis; Ciliated sensory neurons; Hormesis; Mitochondria; Neurodegenerative disorders;
Invitro free radical scavenging, cytotoxic and acetylcholinesterase inhibitory activities of Leucas martinicensis
Keywords: اختلالات نوروژنیک; Neurodegenerative disorders; Oxidative stress; Flavonoids and phenolic compounds;
Acetylcholinesterase inhibitory activity of phlorotannins isolated from the brown alga, Ecklonia maxima (Osbeck) Papenfuss
Keywords: اختلالات نوروژنیک; Acetylcholinesterase; Ecklonia maxima; Phloroglucinol derivatives; Neurodegenerative disorders;
Drain of the brain: low-affinity p75 neurotrophin receptor affords a molecular sink for clearance of cortical amyloid β by the cholinergic modulator system
Keywords: اختلالات نوروژنیک; Neurodegenerative disorders; Alzheimer's disease; p75 neurotrophin receptor; Basal forebrain cholinergic neurons; Amyloid β;
Therapeutic potential of GABAB receptor ligands in drug addiction, anxiety, depression and other CNS disorders
Keywords: اختلالات نوروژنیک; GABA; Anxiety; Addiction; Depression; Neurodegenerative disorders; CNS disorders;
An approach to developmental regression
Keywords: اختلالات نوروژنیک; developmental regression; gene therapy; neurodegenerative disorders; regression
Cognitive dysfunction and REM sleep behavior disorder: Key findings in the literature and preliminary longitudinal findings
Keywords: اختلالات نوروژنیک; Idiopathic REM sleep behavior disorder; Neuropsychological performances; Neurodegenerative disorders; Synucleinopathies; Extrapyramidal disorders
TEP/IRM hybride en neuro-imagerie
Keywords: اختلالات نوروژنیک; TEP/IRM; Neuro-imagerie; Épilepsie; Oncologie; Maladies neurodégénératives; DémencePET/MRI; Neuro-imaging; Epilepsy; Oncology; Neurodegenerative disorders; Dementias
Copper interactions with DNA of chromatin and its role in neurodegenerative disorders
Keywords: اختلالات نوروژنیک; Human brain; Chromatin; DNA; Copper; Neurodegenerative disorders
EEG bei Enzephalopathien
Keywords: اختلالات نوروژنیک; EEG; Enzephalopathie; neurodegenerative Krankheiten; vaskuläre Erkrankungen; metabolische StörungenEEG; encephalopathy; neurodegenerative disorders; vascular disorders; metabolic disorders
Dopamine
Keywords: اختلالات نوروژنیک; Neurodegenerative disorders; Parkinsonism; Dopamine; PET; Imaging biomarkers; Diagnosis; Disease progression; Therapeutic intervention;
Deficient Rab11 activity underlies glucose hypometabolism in primary neurons of Huntington’s disease mice
Keywords: اختلالات نوروژنیک; Neurodegenerative disorders; Huntington’s disease; Primary neurons; Glucose uptake; Rab11
Nanotechnology for neurodegenerative disorders
Keywords: اختلالات نوروژنیک; Nanoparticles; Nanomaterials; Neurodegenerative disorders; Brain; Blood–brain barrier
ATAXIN2 CAG-repeat length in Italian patients with amyotrophic lateral sclerosis: risk factor or variant phenotype? Implication for genetic testing and counseling
Keywords: اختلالات نوروژنیک; Spinocerebellar ataxia type 2; Ataxin 2; ATXN2; Amyotrophic lateral sclerosis; Neurodegenerative disorders; Triplet repeats; CAG; Polyglutamine disorders;
Rapid detection of large expansions in progressive myoclonus epilepsy type 1, myotonic dystrophy type 2 and spinocerebellar ataxia type 8
Keywords: اختلالات نوروژنیک; dynamic mutations; neurodegenerative disorders; repeat primed PCR (RP-PCR)mutacje dynamiczne; choroby neurodege-neracyjne; reakcja RP-PCR
PerspectivesAdvancing Alzheimer's disease diagnosis, treatment, and care: Recommendations from the Ware Invitational Summit
Keywords: اختلالات نوروژنیک; Alzheimer's disease; Neurodegenerative disorders; Dementia; Research priorities; Policy priorities; Health policy recommendations;
Nanotechnology for neurodegenerative disorders
Keywords: اختلالات نوروژنیک; Nanoparticles; Nanomaterials; Neurodegenerative disorders; Brain; Blood–brain barrier
Herpes simplex virus type 1-based amplicon vectors for fundamental research in neurosciences and gene therapy of neurological diseases
Keywords: اختلالات نوروژنیک; Amplicons; HSV-1-derived vectors; Nervous system; Neurodegenerative disorders; Experimental gene therapy
Disturbed sleep/wake rhythms and neuronal cell loss in lateral hypothalamus and retina of mice with a spontaneous deletion in the ubiquitin carboxyl-terminal hydrolase L1 gene
Keywords: اختلالات نوروژنیک; Alzheimer's disease; Circadian rhythms; Clock genes; gad; Hypocretin; Locomotor activity; Melanopsin; Neurodegenerative disorders; Orexin; Parkinson's disease; UCH-L1;
Emotion recognition in Huntington's disease: A systematic review
Keywords: اختلالات نوروژنیک; Huntington's disease; Emotion recognition; Cognition; Neurodegenerative disorders;
Characterization of the glycated human cerebrospinal fluid proteome
Keywords: اختلالات نوروژنیک; AD; Alzheimer's disease; AGEs; Advanced glycation end products; ALS; Amyotrophic lateral sclerosis; BAC; Boronate affinity chromatography; β2M; Beta-2 microglobulin; CID; Collision-induced dissociation; CJD; Creutzfeld-Jakob disease; CML; Nε-(carboxym
Functional interactions within striatal microcircuit in animal models of Huntington's disease
Keywords: اختلالات نوروژنیک; striatum; neurodegenerative disorders; interneurons; HD animal models; synaptic changes; corticostriatal pathwayA2a, adenosine receptor; ACh, acetylcholine; BDNF, brain-derived neurotrophic factor; cAMP, cyclic AMP; CB1, cannabinoid receptor type 1; ChAT,
Neuroactive steroids: focus on human brain
Keywords: اختلالات نوروژنیک; neurodegenerative disorders; mood disorders; GABA-A receptor; neurosteroidsT, testosterone; TSPO, translocator protein 18 kDa
Positive allosteric modulation of metabotropic glutamate receptor 5 down-regulates fibrinogen-activated microglia providing neuronal protection
Keywords: اختلالات نوروژنیک; BBB; blood brain barrier; CDPPB; 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide; CGC; cerebellar granule cells; CNS; central nervous system; DCGIV; (2S,2â²R,3â²R)-2-(2â²,3â²-dicarboxycyclopropyl)glycine; ERK1/2; extracellular signal-regulated kinas
Serotonin and dopamine striatal innervation in Parkinson's disease and Huntington's chorea
Keywords: اختلالات نوروژنیک; Basal ganglia; Neurodegenerative disorders; Dopaminergic striatal innervation; Serotoninergic striatal innervation; Movement disorders; 5-HT; 5-hydroxytryptamine (serotonin); CD; caudate nucleus; D; dorsal; DA; dopamine; HD; Huntington's disease; ic; in